Patient Name: Marquez, Louise

Drug Action Indication/ Contraindication Nursing responsibilities

Generic Name: Mechanism of Action:  Indication:   12 Rights
nalbuphine  Monitor for allergic reactions
 Narcotic agonist-analgesic of kappa opiate  For the relief of moderate to severe pain.  Monitor IV site for VIP Score
receptors and partial antagonist of mu  Monitor Respiratory depression
Brand Name: Nubian opiate receptors; inhibits ascending pain Contraindication:
pathways, thus altering response to pain;  Significant respiratory depression
Classification: produces analgesia, respiratory depression,
opioid analgesics and sedation
 Diarrhea associated with toxins,
gastrointestinal obstruction, including
Dosage:  Side Effects: pseudomembranous colitis
 10mg q6h  drowsiness;
 dizziness, spinning sensation;  Acute or severe bronchial asthma,
Route: IV  dry mouth; bradycardia, inflammatory bowel disease
 headache;
 sweating;
 cold, clammy skin; or.
 nausea, vomiting.
 Patient Name: Marquez, Louise

Drug Action Indication/ Contraindication Nursing responsibilities

Generic Name: Mechanism of Action:  Indication:   12 Rights
promethazine  Monitor for allergic reactions
 Promethazine is an antagonist of histamine  Promethazine tablets and suppositories are  Monitor IV site for VIP Score
H1, post-synaptic mesolimbic dopamine, indicated to treat rhinitis, allergic  Monitor respiratory function in patients
Brand Name: alpha adrenergic, muscarinic, and NMDA conjunctivitis, allergic reactions to blood or with respiratory problems, particularly
Phenadoz receptors. The antihistamine action is used plasma, dermographism, anaphylactic children. Drug may suppress cough
to treat allergic reactions. Antagonism of reactions, sedation, nausea, vomiting, pain, reflex and cause thickening of bronchial
Classification: muscarinic and NMDA receptors contribute motion sickness, and allergic skin reactions secretions
Promethazine HCl to its use as a sleep aid, as well as for Promethazine cough syrup with
anxiety and tension. Antagonism of phenylephrine and codeine is indicated to
histamine H1, muscarinic, and dopamine relieve cough and upper respiratory
Dosage: 
receptors in the medullary vomiting center symptoms, and nasal congestion associated
 20mg/1ml q6h make promethazine useful in the treatment with allergy or the common cold.
of nausea and vomiting.
Route: IV Contraindication:
Before taking promethazine, tell your doctor or
Side Effects: pharmacist if you are allergic to it; or to any other
 Drowsiness phenothiazines (such as prochlorperazine); or if
 Dizziness you have any other allergies. This product may
 Constipation contain inactive ingredients, which can cause
 blurred vision allergic reactions or other problems. Talk to your
 dry mouth may occur. pharmacist for more details.
 Patient Name: Marquez, Louise

Drug Action Indication/ Contraindication Nursing responsibilities

Generic Name: Mechanism of Action:  Indication:   12 Rights
oxytocin  Monitor for allergic reactions
 Oxytocin increases the amplitude and  Pitocin is indicated for the initiation or  Monitor IV site for VIP Score
frequency of uterine contractions, which improvement of uterine contractions, where  Monitor FHT
Brand Name: transiently impede uterine blood flow and this is desirable and considered suitable for  Discontinue infusion if pt has uterine
Pitocin decrease cervical activity, causing dilation reasons of fetal or maternal concern, in hyperactivity and/or fetal distress
and effacement of the cervix. Oxytocin order to achieve vaginal delivery. It is
Classification: causes contraction of the myoepithelial indicated for (1) induction of labor in
Promethazine HCl cells surrounding the alveolar ducts of the patients with a medical indication for the
of the breast. initiation of labor, such as Rh problems,
Side Effects: maternal diabetes, preeclampsia at or near
Dosage: 
term, when delivery is in the best interests
 10 units/mL  Slow heart rate of mother and fetus or when membranes are
q12hrs  Fast heart rate prematurely ruptured and delivery is
 Premature ventricular complexes and other indicated.
Route: IV irregular heartbeats (arrhythmias)
 Permanent central nervous system (CNS) or Contraindication:
brain damage, and death secondary to
 Significant cephalopelvic disproportion
suffocation
 Unfavorable fetal positions or
 Neonatal yellowing of skin or eyes
presentations, e.g., transverse lies, which
(jaundice)
are undeliverable without conversion before
 Fetal death delivery
 Low Apgar score (5 minutes)  Obstetric emergencies that favor surgery
 Fetal distress where delivery is not
imminent
 Where adequate uterine activity fails to
achieve satisfactory progress
 Hyperactive or hypertonic uterus
 Patient Name: Marquez, Louise

Drug Action Indication/ Contraindication Nursing responsibilities

Generic Name: Mechanism of Action:  Indication:   12 Rights
Celecoxib  Avoid taking other NSAIDs
 Celecoxib is chemically designated as 4-[5-  CELEBREX is indicated for the  Avoid alcohol
(4-methylphenyl)- 3-(trifluoromethyl)-1H- management of the signs and symptoms of  Discontinue if positive with skin rash
Brand Name: pyrazol-1-yl] benzenesulfonamide and is a osteoarthritis, rheumatoid arthritis, juvenile
CeleBREX diaryl-substituted pyrazole. The mechanism rheumatoid arthritis in patients 2 years and
of action of celecoxib is due to selective older, and ankylosing spondylitis; for the
Classification: inhibition of cyclooxygenase-2 (COX-2), management of acute pain in adults, and for
NSAIDs which is responsible for prostaglandin the management of primary dysmenorrhea.
synthesis, an integral part of the pain and
inflammation pathway. This pharmacologic
Dosage:  Contraindication:
activity gives celecoxib its analgesic, anti-
 400mg/cap OD inflammatory, and antipyretic effects.  Known hypersensitivity to celecoxib or any
q5days post- Celecoxib does weakly inhibit COX-1 and, components of the drug product or
sebum therefore, may affect platelet function to a sulfonamides
lesser extent as compared to aspirin.  History of asthma, urticaria, or other
Route: Oral allergic-type reactions after taking aspirin
or other NSAIDs
Side Effects:
 In the setting of CABG surgery
 stomach pain, heartburn, gas, diarrhea,
constipation, nausea, vomiting;
 swelling in your hands or feet;
 dizziness; or
 cold symptoms such as stuffy nose,
sneezing, sore throat
 Patient Name: Marquez, Louise

Drug Action Indication/ Contraindication Nursing responsibilities

Generic Name: Mechanism of Action:  Indication:   12 Rights
cefuroxime  Monitor signs of allergic reactions and
 Cefuroxime is a bactericidal agent that acts  Lower Respiratory Tract Infections, anaphylaxis including pulmonary
by inhibition of bacterial cell wall including pneumonia, caused by symptoms (tightness in the throat and
Brand Name: synthesis. Cefuroxime has activity in the Streptococcus pneumoniae, haemophiles chest, wheezing, cough dyspnea) or skin
Zinacef presence of some beta-lactamases, both influenzae (including ampicillin-resistant reactions (rash, pruritus, urticaria). Notify
penicillinases and cephalosporinases, of strains), Klebsiella spp., Staphylococcus physician or nursing staff immediately if
Classification: Gram-negative and Gram-positive bacteria. aureus (penicillinase-and non-penicillinase- these reactions occur.
cephalosporin antibiotic producing strains), Streptococcus pyogenes,  Monitor renal, hepatic, and hematologic
and Escherichia coli. function periodically with prolonged
Side Effects: therapy. Monitor prothrombin time in
 Urinary Tract Infections caused by
Dosage:   hives, patients at risk of prolongation during
Escherichia coli and Klebsiella spp.
 500mg/tab BID cephalosporin therapy (nutritionally-
 difficulty breathing,  Klebsiella spp., and Enterobacter spp.
q7days post- deficient, prolonged treatment, renal or
 swelling of face, lips, tongue, or throat,  Meningitis caused by Streptococcus hepatic disease).
cebum  dark urine, pneumoniae, Hemophilus influenzae
 easy bruising or bleeding, (including ampicillin-resistant strains),
Route: IM  fast, pounding, or irregular heartbeat, Neisseria meningitidis, and Staphylococcus
 seizures, aureus (penicillinase-and non-penicillinase-
 unusual weakness, producing strains).
 yellowing of the eyes or skin (jaundice) Contraindication:
 Allergic to the cephalosporin group of
antibiotics.
 diarrhea from an infection with Clostridium
difficile bacteria
 chronic kidney disease stage 4 (severe)
 chronic kidney disease stage 5 (failure)
 Patient Name: Marquez, Louise

Drug Action Indication/ Contraindication Nursing responsibilities

Generic Name: Mechanism of Action:  Indication:   12 Rights
Multivitamins and  In case of accidental overdose or at
 Clusivol OB (Calcium Carbonate) acetate,  It is indicated for the prevention and
Minerals the first sign of any adverse reaction,
when taken with meals, combines with treatment of vitamin and mineral
discontinue use and seek professional
dietary phosphate to form an insoluble deficiencies during pregnancy and lactation.
Brand Name: assistance immediately.
Clusivol OB (Calcium Carbonate)
 Monitor blood pressure and oxygenation
Clusivol OB phosphate complex, which is excreted in
the feces, resulting in decreased serum Contraindication:
Classification: phosphorus concentration.  This product is contraindicated in patients
multivitamins with who are allergic (hypersensitive) to its
minerals Side Effects: active ingredients listed under Description.
 Do not exceed recommended daily
 Overdosage: diarrhea, nausea, constipation, dose/amount.
Dosage:  abdominal discomfort, excessive supply of  Product contains iron which could be
 1 Tab qDaily vitamin A (hyper-vitaminosis A) and D harmful to children if taken in large doses.
(hyper-vitaminosis D).
 If the patients is taking other vitamin
 CNS: rarely - a state of arousal. supplement, which may also contain
Route: Oral
 Cardiovascular system: rarely - pain in the Vitamin A, make sure to read the label to
heart, tachycardia. ensure that the patient do not exceed the
 Allergic reactions: rarely - urticaria. upper tolerable intake levels of 3000 mcg
RE (retinol equivalent)/day. Excessive
amount of Vitamin A during pregnancy
may be harmful.
 Use in Pregnancy & Lactation - excessive
amount of Vitamin A during pregnancy
may be harmful.