ASAM AMINO NON-STANDAR

 Merupakan asam amino diluar 20 mcm as. Amino standar

 Terjadi karena modifikasi yang terjadi setelah suatu asam amino standar menjadi
protein.
 Kurang lebih 300 asam amino non standar dijumpai pada sel
modifikasi serin yang mengalami fosforilasi oleh protein kinase

• modifikasi prolin  dlm proses modifikasi posttranslasi, oleh prokolagen prolin

hidroksilase.
• Ditemukan pada kolagen untuk menstabilkan struktur

• Dari modifikasi Glu oleh vit K.

•  karboksi glutamat mampu mengikat Ca  penting utk penjendalan darah.
 • Ditemukan pd protein protombin
AMINO ACID PLANT V ANIMAL
 Plants are able to make their own amino acids that they need to live - providing they
can obtain a sufficient amount of nitrate from the soil.
 They convert the nitrate into amino groups which then bond to organic groups which
are the product of photosynthesis.
 Animals however cannot manufacture 10 of the amino acids that they need (essential
amino acids) and therefore must eat protein which is then digested into amino acids.
 Animals cannot store excess amino acids, the amino group makes them toxic if too
much is present.
 The amino group is removed in a process called deamination - this takes place in the
liver in animals.
 The removed amino groups form urea and is removed in the urine.