Scribd Logo
Upload

Welcome to Scribd!

  • Obstetrics

    Uploaded by

    mohamed abd elsalam
    7 views8 pages
    This document discusses endometrial carcinoma (cancer of the uterus). It describes the etiology as being related to unopposed estrogen exposure, most commonly seen in post-menopausal women. The cancer spreads directly through the uterus and also via lymphatic and blood vessels. Early stage 1 disease is confined to the uterus, while stage 4 involves distant metastasis. Symptoms include abnormal vaginal bleeding and discharge, as well as pain from the local effects of tumor growth or spread. Risk factors include increased age, white race, diabetes, obesity, and excess estrogen exposure.

    Original Description:

    Obstetrics

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    This document discusses endometrial carcinoma (cancer of the uterus). It describes the etiology as being related to unopposed estrogen exposure, most commonly seen in post-menopausal women. The cancer spreads directly through the uterus and also via lymphatic and blood vessels. Early stage 1 disease is confined to the uterus, while stage 4 involves distant metastasis. Symptoms include abnormal vaginal bleeding and discharge, as well as pain from the local effects of tumor growth or spread. Risk factors include increased age, white race, diabetes, obesity, and excess estrogen exposure.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    7 views8 pages

    Obstetrics

    Uploaded by

    mohamed abd elsalam
    This document discusses endometrial carcinoma (cancer of the uterus). It describes the etiology as being related to unopposed estrogen exposure, most commonly seen in post-menopausal women. The cancer spreads directly through the uterus and also via lymphatic and blood vessels. Early stage 1 disease is confined to the uterus, while stage 4 involves distant metastasis. Symptoms include abnormal vaginal bleeding and discharge, as well as pain from the local effects of tumor growth or spread. Risk factors include increased age, white race, diabetes, obesity, and excess estrogen exposure.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 8

    Endometrial carcinoma

    Endometrial carcinoma
    general scheme
    endometrial carcinoma
    endometrium malignancy
    uterus direct

    Etiology

    unopposed hyper estrogenemia

    macroscopy
    specules
    cauliflower
    malignant ulcer
    infiltrated

    microscopic
    adeno-carcinoma

    tumor
    Spread
    stages
    spread

    Page | 1
    Endometrial carcinoma

    direct 
    lymphatic 
    blood 

    endometrial carcinoma
    spread
    direct spread

    peritonitis

    lymphatic
    cancer cervix
    cancer ovary
    Internal iliac
    external iliac
    common iliac
    para aortic
    cisterna chyeli
    thoracic duct
    wirchow lymph node

    blood
    late , rare

    1,2,3,4 stages

    lies to organs stage 1

    a,b stage4
    4a rectum , bladder
    4b distant metastasis

    Stage 2,3

    schema

    Page | 2
    Endometrial carcinoma

    Schema

    Clinical pictures

    symptoms, signs

    symptoms
    ( general , abdominal , local )

    general
    anemia , cachexia , Hge , jaundice

    swollen abdomen
    swollen local
    swollen local
    cause of death defect

    tumors
    Cancer cervix , cancer ovary , cancer endometrium
    vagina vulva

    symptoms
    bleeding
    cancer endometrium
    bleeding
    ( any post menopausal bleeding is considered endometrial carcinoma until proved otherwise )

    60

    ovary 60

    estrogen

    Page | 3
    Endometrial carcinoma

    E1

    supra real gland


    testosterone

    1945
    testosterone
    supra renal

    fat tissue by aromatase to E1

    E1 is carcinogenic

    bleeding
    post menopause

    bleeding

    endogenous
    poly cystic ovary
    exiogenous
    E abuse

    etiology
    60 Age
    white races Race

    paragraph

    Hyper estrogenimia

    diabetic , hypertensive , obese

    Page | 4
    Endometrial carcinoma

    pre menopausal

    symptoms
    discharge

    mucoid
    muco purulent

    2ry infection

    Any female genital tract cancer is considered potentially infected

    leukoria

    symptom
    pain

    intermitted colicy lower abdominal pain

    Constant lower abdominal pain

    cervix
    malignant cell

    hematometra

    Page | 5
    Endometrial carcinoma

    Genital malignancy is considered infected

    pyometra hematometra

    pus … pus

    abcess
    abcess
    Constant dull aching lower abdominal colicy pain

    pain

    pyometria

    pain
    pain

    visceral pain somatic pain

    pain
    abdomen

    dykainasia
    dysurea

    late early
    very very late

    Malignant cyst

    stage
    stage 4
    Stage 4
    Stage 4 a

    Page | 6
    Endometrial carcinoma

    endometrium
    visceral pain rectum , bladder

    somatic pain

    down shouting pain

    Pri sacral plexus

    lower segment

    Utrosacral ligament

    late early

    visceral pain
    rectum , bladder

    somatic pain
    prisacral plexus

    constant dull aching lower abdominal pain

    symptoms
    bleeding
    discharge
    tear
    swelling

    Page | 7
    Endometrial carcinoma

    swelling

    small atrophic uterus

    1a

    D&C
    swelling
    Anemia , cachexia

    Fibroid
    2- associated pyometria

    pyometria

    www.facebook.com/dr.tafreegh

    Page | 8

    You might also like