Françoise Barré-Sinoussi

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Françoise Barré-Sinoussi
Born 30 July 1947 (age 74)
Paris, France
Nationality French
Alma mater University of Paris
Known for Co-discoverer of HIV
Awards 2008 Nobel Prize in Physiology or Medicine
Scientific career
Fields Virology
Institutions Pasteur Institute

(French:  born 30 July 1947) is a French virologist and Director of the Regulation of

Retroviral Infections Division (French: Unité de Régulation des Infections Rétrovirales) and
Professor at the Institut Pasteur in Paris, France. Born in Paris, France, Barré-Sinoussi
performed some of the fundamental work in the identification of the human
immunodeficiency virus (HIV) as the cause of AIDS. In 2008, Barré-Sinoussi was awarded
the Nobel Prize in Physiology or Medicine, together with her former mentor, Luc
Montagnier, for their discovery of HIV.[2] She mandatorily retired from active research on
August 31, 2015 and fully retired by some time in 2017. [3]

Early life
Barré-Sinoussi was interested in science from a very young age. During her vacations as a
child, she would spend hours analyzing insects and animals, comparing their behaviours
and trying to understand why some run faster than others for example. Soon after, Barré-
Sinoussi realized she was very talented in the sciences compared to her humanity
courses.
She expressed interest to her parents that she would like to attend university to study
science or become a researcher. Barré-Sinoussi admitted that she was more interested in
becoming a doctor but at the time she was under the false impression that studying
medicine was both more expensive and lengthier than a career in science. After two years
studying at the university, Barré-Sinoussi attempted to find part-time work in a laboratory
to ensure that she had made the right career choice. After nearly a year of searching for
laboratory work, she was finally accepted by the Pasteur Institute. Her part-time work at
the Pasteur Institute quickly became full-time.
She began to only attend university to take the exams and had to rely on her friends’ class
notes because she was not regularly attending class. However, Barré-Sinoussi was
actually scoring higher on her exams than before, because she finally had the motivation
because she had realized a career in science was what she wanted to do.
Academic career

The human T-lymphotropic virus type 1 (HTLV-1), and the human immunodeficiency virus
(HIV).
Barré-Sinoussi joined the Pasteur Institute in Paris in the early 1970s. She received her
PhD in 1974 and interned at the U.S. National Institutes of Health before returning to the
Pasteur Institute in Montagnier's unit.
The Pasteur Institute (is a French non-profit private foundation dedicated to the study
of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who
invented pasteurization and vaccines for anthrax and rabies. The institute was founded on 4 June 1887,
and inaugurated on 14 November 1888.
For over a century, the Institut Pasteur has researched infectious diseases. This
worldwide biomedical research organization based in Paris was the first to isolate HIV, the virus that
causes AIDS, in 1983. Over the years, it has been responsible for discoveries that have enabled
medical science to control diseases such
as diphtheria, tetanus, tuberculosis, poliomyelitis, influenza, yellow fever, and plague.
Since 1908, ten Institut Pasteur scientists have been awarded the Nobel Prize for medicine
and physiology—the 2008 Nobel Prize in Physiology or Medicine was shared between two Pasteur
scientists.

During the early AIDS epidemic in 1981-1984, the viral cause of the outbreak had not yet
been identified. Working with Luc Montagnier, Jean-Claude Chermann and others at the
institute, Barré-Sinoussi isolated and grew a retrovirus from a biopsied swollen lymph node
of a patient at risk for AIDS. This virus would later be known as HIV-1, the causative agent
behind the outbreak. This discovery allowed for the development of diagnostic tests to aid
in controlling the spread of the virus, for informing policy on the treatment of people living
with AIDS, and for many important advancements in the science of HIV/AIDS that
ultimately saved countless lives.
Luc Montagnier  French: 18 August 1932 – 8 February 2022) was a French virologist and joint recipient,
with Françoise Barré-Sinoussi and Harald zur Hausen, of the 2008 Nobel Prize in Physiology or
Medicine for his discovery of the human immunodeficiency virus (HIV).[4] He worked as a researcher at
the Pasteur Institute in Paris and as a full-time professor at Shanghai Jiao Tong University in China.[5]
During the COVID-19 pandemic, Montagnier promoted the conspiracy theory that SARS-CoV-2, the
causative virus, was deliberately created and escaped from a laboratory.[6] Such a claim has been
rejected by other virologists.[7][8][9] He has been criticised by other academics for using his Nobel prize
status to "spread dangerous health messages outside his field of knowledge". [10]
Barré-Sinoussi started her own laboratory at the Pasteur Institute in 1988. Among Barré-
Sinoussi's many recent research contributions are studies of various aspects of the
adaptive immune response to viral infection, the role of innate immune defenses of the
host in controlling HIV/AIDS, factors involved in mother-to-child transmission of HIV, [ and
characteristics that allow a small percentage of HIV-positive individuals, known as elite
suppressors or controllers, to limit HIV replication without antiretroviral drugs. She has co-
authored over 240 scientific publications, has participated in over 250 international
conferences, and has trained many young researchers.
Barré-Sinoussi has actively contributed to several scientific societies and committees at
the Institute Pasteur as well as to other AIDS organizations, such as the National Agency
for AIDS Research in France. She has also been implicated at an international level,
notably as a consultant to the WHO and the UNAIDS-HIV.
Since the 1980s, Barré-Sinoussi has initiated collaborations with developing countries and
has managed multidisciplinary networks with dedication. In 2016, she was interviewed by
the Sunday Observer and reflected on how Jamaica is dealing with HIV. She constantly
works on establishing permanent links between basic research and clinical research with
the aim of achieving concrete improvements in the areas of prevention, clinical care, and
treatment.
Professor Barré-Sinoussi believes that scientists have made steady progress given the
development of antiretroviral treatment which UNAIDS states is being accessed by 17
million of the people globally who are living with AIDS, but finding a cure, or cures, will take
time, and a continued investment in research. As the co-chair of the 21st International
AIDS Society (IAS), she said the search for curative strategy of HIV is a goal of paramount
importance and a priority for the future of HIV research. Moreover, even though research
to achieve such cures is in a formative stage, significant advances are being made
towards a HIV cure.
In 2009, she wrote an open letter to Pope Benedict XVI in protest over his statements that
condoms are at best ineffective in the AIDS crisis.
In July 2012 Barré-Sinoussi became President of the International AIDS Society.

The International AIDS Society (IAS) is the world's largest association of HIV/AIDS professionals, with

11,600 members from over 170 countries as of July 2020, including clinicians, people living with HIV,
service providers, policy makers and others. It aims to reduce the global impact of AIDS through
collective advocacy. Founded in 1988, IAS headquarters are located in Geneva, and its president since
August 2022 is Sharon Lewin.
The IAS hosts the biennial International AIDS Conference, the IAS Conference on HIV Science, and the
HIV Research for Prevention Conference.

Awards
Barré-Sinoussi shared the 2008 Nobel Prize in Physiology or Medicine with Luc
Montagnier for their co-discovery of HIV, and with Harald zur Hausen, who discovered the
viral cause of cervical cancer that led to the development.
In addition to the Nobel Prize, Barré-Sinoussi has received awards including:

 The Sovac Prize

 The Körber European Science Prize (aka Körber Foundation Prize for the Promotion of
European Science)
 The Prize of the French Academy of Sciences (Académie des sciences)
 The King Faisal International Prize
 The International AIDS Society Prize
 Barré-Sinoussi was named an Officer of the National Order of the Legion of
Honour (Ordre national de la Légion d’honneur) in 2006 and was raised to Commander
in 2009. She was promoted to the dignity of Grand Officer in 2013. [24]
 She received an honorary Doctor of Science degree from Tulane University in May
2009, and an honorary Doctor of Medicine from the University of New South Wales in
July 2014.

Habiendo leído el texto complete la siguiente guía.

1. Observe el siguiente texto. Identifique

Identifique el género al que pertenece.

Dónde está sacado:

En su opinión quien/es lo escribió/escribieron :

Dirigido a quien:

En qué ámbito suele circular:

Para qué fue escrito:

¿Encuentra interesante esta información? ¿Para ser utilizada en qué contexto?

2.Considere y comente. Cuanto sabe (conocimientos previos) sobre la vida de este

hombre.

3. ¿Qué información puede relevar del texto ? indique y mencione qué le ayudó a
acceder a dicha información. Identifique información sobre el instituto Pasteur.
Quien fue Luc MOntagnier?

4. Identifique y resalte las marcas textuales. ¿Qué le dicen estas marcas?

5. Subraye los elementos del texto que ha podido comprender.

6. Realice un listado con aquellos elementos (cognados) o aspectos del texto que
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7. Considerando todo lo relevado hasta el momento y teniendo en cuenta su

propósito lector, identifique los conceptos clave sobre la vida de FRANCOISE
BARRE SINOUSI.
¿Qué paso en 2008?. ¿Cuáles fueron sus reconocimientos? ¿ Dónde trabajo?, subraye
(según lo entiende) que menciona el articulo. ¿Qué reconoce como paratexto?.
Reflexión sobre la lectura:
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¿Pudo notar cambios en cómo se sentía a lo largo de este proceso de lectura,

desde la primera vez que intentó “leer” el texto en inglés y a medida que avanzó
en las actividades?

¿Qué elementos le facilitaron la lectura? ¿Qué elementos le dificultaron la

lectura?