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Maxilact®
Generations of winning lactase. We make it happen
Presenter name

January, 2015
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Lactase leader since 1964

• It was a groundbreaking innovation when DSM was the first to come
with a solution to help everyone enjoy the benefits of healthy
dairy.
• In the meantime, DSM has grown to become the world’s largest
suppliers of dairy health ingredients.
• What has not changed – we continue to be the primary producer of
lactase in the world.

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Maxilact® LGi vs LG
DSM is changing the Maxilact® portfolio to raise the overall quality standard
• The core of the Maxilact® product range consists of Maxilact® LGi, LGX and LAGX.
• Since the introduction of Maxilact® LGi in 2013, customers have confirmed a
consistent equal or better performance of Maxilact® LGi compared to Maxilact® LG.
• Maxilact® LG does not provide any benefits over Maxilact® LGi or LGX. Therefore it
has been decided to discontinue the LG range per January 1st 2016

Maxilact® LG versus LGi

Product Available
Activity Shelf life Features Benefits
range pack sizes

• 5 kg
Maxilact® 5000
• 20 kg 24 months • High purity • Good flavor stability
LG NLU/g
• 1200 kg

• 5 kg • High purity • Excellent flavor stability

Maxilact® 5000
• 20 kg 24 months • Free of arylsulfatase • Ideal for sugared dairy products
LGi NLU/g
• 1000 kg • Free of invertase • Label friendly

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Clean flavor expert

• The shelf life of lactose-free products can be limited because of
taste deterioration.
• During extensive scientific research, DSM found that arylsulfatase –
a common impurity in lactase preparations - is causing this off-
flavor by converting a natural component in milk (s-cresol).
• This patented technology has enabled us to develop arylsulfatase-
free Maxilact®.

para-cresol
s-cresol, naturally occuring in milk, is converted in
p-cresol by arylsulfatase. p-cresol is a component
also present in pig odor and human sweat.

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Clean flavor expert

• Application tests validate the absence of arylsulfatase and improved
quality of arylsulfatase-free Maxilact® in an accelerated shelf life test.

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Invertase free Maxilact® LGi

• Invertase is a common lactase

impurity:
– It breaks down sugar
(sucrose) into fructose
and glucose.
– This changes the
ingredient composition.
– It can result in changes in
texture, sugar taste or
mouth feel during shelf
life.
• Maxilact® LGi improves
product stability over shelf
life in sugared lactose-free
dairy products.

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Sweetness enhancement explained

• Natural enzyme Maxilact® breaks down lactose into better digestible and sweeter
forms of sugar. These components have a higher relative sweetness than lactose.
• This allows for a sugar reduction of 1-2g /100g of yogurt
• Maxilact® range contains unique products specifically suited for natural sweetness
enhancement or sugar reduction.

Relative Sweetness:
Sucrose 100
Lactose 22
Glucose 45
Galactose 42
Fructose 135

Graph 4. Sweetness intensity of different sugars in time. Adapted from Hull

P. (2010) Glucose Syrups: Technology and Applications, Wiley Blackwell

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 Why Maxilact® LGi?

• Maxilact® is the leading lactase in the market of the highest purity:

Proprietary technology to prevent off-flavor development

Invertase-free lactase: ideal for sugared dairy products

• DSM is the primary producer of lactase and has an excellent track record in
quality, reliability and security of supply;

• DSM offers a unique portfolio of health ingredients – including vitamins,

minerals, omega’s and other value-adding ingredients.

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 While making reasonable efforts to ensure that all information in this presentation is accurate
and up to date, DSM makes no representation or warranty of accuracy, reliability, or
completeness of the information. The information provided herein is for the informational
purposes only.

This publication does not constitute or provide scientific advice and is without warranty of any
kind, express or implied. In no event shall DSM be liable for any damage arising from the reader’s
reliance upon, or use of, this presentation. The reader shall be solely responsible for any
interpretation or use of the materials contained herein.
FOR INTERNAL USE ONLY

Maxilact® product range

Lactase portfolio

Product Available
Activity Shelf life Features Benefits
range pack sizes

• 5 kg • High purity • Excellent flavor stability

Maxilact® 5000
• 20 kg 24 months • Free of arylsulfatase • Ideal for sugared dairy products
LGi NLU/g
• 1000 kg • Free of invertase • Label friendly

• 5 kg 5000 • Very high purity

Maxilact® • Excellent flavor stability
• 20 kg NLU/g 24 months • Free of arylsulfatase
LGX • Label friendly
• 1000 kg • Suitable for sterile filtration

2000 • Aseptic packaging suitable

Maxilact® • 5.75 kg • Suitable for aseptic dosing
NLU/g 12 months for FlexDos
LAGX • 11.5 kg • Excellent flavor stability
• Free of arylsulfatase

• Processing aid for producing:

 Refined acid-whey hydrolyzates
Maxilact® 5000 Acid lactase (liquid) for whey
20 kg 24 months  Lactose-reduced whey powders
A4 ALU/g processing
 Sweeter tasting acid-whey
permeate

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Quality improvement in 2015

Off-flavor test
• Introduction to specifications and COA for Maxilact® LGi, LGX and LAGX
• Application test in milk with trained panel to detect flavor defects
• Official DSM QC release test – if flavor defects are observed, batch will be blocked

Enterobacteriaceae
• Are considered superior to coliforms as
indicators of sanitation GMPs
• Coliforms are able to ferment lactose, while the
Enterobacteriaceae ferment glucose
• Introduced as a spec (≤1CFU/ml) for LGi/LGX

Arylsulfatase
• DSM patent EP1954808B1
• Production of a dairy product with a lactase with
low/no arylsulfatase
• To be introduced as a spec for LGi/LGX/LAGX

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Analytical methods for residual lactose

determination in lactose-free dairy products

HPAEC-PAD UF method Cryoscopy method MilkoScan

Description High Performance Standard Freezing point Equipment for
Anion-Exchange photometric method method standard lactose
Chromatography with with enzymatic levels in milk
Pulsed Amperometric hydrolysis of residual
Detection. lactose
Residual
<0.01% 0.1% Not recommended Not recommended
lactose levels
Comments Most accurate Bhoeringer An indicative Can only be
method available in BioAnalysis method which applied when
the market Lactose/Galactose does not deliver equipment is
Test Kit reliable residual adapted by Foss
lactose results for low lactose
contents

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