Local Literature

Types of Summary and

Title how it is related
Author/s Page/s literatures/Stud to your topic
ies
1. Phytochemical Abastillas et 171- Article
composition al., (2023) 182
and A survey of
antibacterial medicinal plants
activity of in a local
selected community in
medicinal Guimbal, Iloilo,
plants in a Philippines
local identified ten
community in plant species.
the Among them,
Philippines. Bambusa
vulgaris and
Alpinia sp. were
selected for
further study.

2. Chemical Cruz,Tiausas 6-14 Journal

composition ,& Aresas Blumea
and (2023) balsamifera, a
antimicrobial traditional
activity of the medicine used
extracts and for diuretic
essential oil of treatment of
Blumea kidney stones in
balsamifera the Philippines,
from the was investigated
Philippines. in this study for
its antibacterial
activity and
chemical
composition.
3. .Chemical Cruz, 6-14 Journal
composition Tiausas, Blumea
and Aresas, & balsamifera, a
antimicrobial Reasonable traditional
activity of the (2023) medicine used
extracts and for diuretic
essential oil of treatment of
Blumea kidney stones in
balsamifera the Philippines,
from the was investigated
Philippines. in this study for
its antibacterial
activity and
chemical
composition.
Methanol
extract, hexane
extract, and
essential oil of
Blumea
balsamifera
leaves were
analyzed.

Cano, 8-17 Journal

4. Phytochemical Pescuela, &
Screening and Antesa
Antimicrobial (2022) The study aimed
Assay of to investigate
Selected Plant the
Extracts with phytochemical
Ethnopharmac screening and
ological antibacterial
Potential for activity of
Wound ethanolic
Healing. extracts from six
herbal plants
commonly used
in the
Philippines to
 promote wound
healing. The
plants studied
were
Caesalpinia
sappan
(Sibukao),
Jatropha curcas
(Tuba-tuba),
Lantana camara
(Kantutay),
Mimosa pudica
(Makahiya),
Moringa oleifera
(Malunggay),
and Psidium
guajava (Guava)

5. Blumea None 1-3 Article Sesquiterpenes

camphor/Sam known as
bong - blumeaenes and
Herbanext samboginone as
Laboratories, well as
Inc. Herbanext antioxidant
Laboratories, flavonoids like
Inc. - Healthier blumeatin,
Solutions quercetin,
From Nature. rhamnetin,
tamarixetin, and
luteolin are
present in
Blumea
balsamifera
(Sambong).
Camphor,
borneol,
isoborneol,
terpineol,
caryophyllene,
guaiol, and
eugenol are
among the
volatile oils
extracted from
Sambong.
 Sambong has a
wide range of
pharmacological
actions,
including those
that are
anticancer,
hepatoprotectiv
e, antioxidant,
antibacterial,
anti-
inflammatory,
anti-
melanogenic,
platelet
aggregation,
wound healing,
and anti-obesity.
Kidney stones,
cuts, wounds,
rheumatism,
diarrhoea,
spasms, colds,
coughs, and
hypertension
are all treated
with it as a
herbal remedy.
The technology
for sambong
herbal medicine
tablets,
specifically for
anti-urolithiatic
reasons, has
even been
created by the
Philippine
Council for
Health Research
and
Development
and is currently
on the market.
6. Phytochemical Aguirre et 2 Article This study
Screening, al., (2023) focused on
Macronutrient three plants that
Content, the Palawan
 Antimicrobial tribe in
and Cytotoxic Bataraza,
Properties of Palawan, ate:
Selected Ardisia
Edible Plants iwahigensis
consumed by Elmer,
the Palaw’an Baccaurea
tribe in gracilis Merr.,
Bataraza, and Manihot
Palawan, glaziovii Mll.Arg.
Philippines. In particular, the
crude ethanol
extracts of the
fresh and/or air-
dried leaves'
phytochemical
components,
macronutrient
concentrations,
antibacterial
activities, and
toxicity were
identified.
Alkaloids,
flavonoids,
sterols, and
tannins were
found in both
air-dried leaves
and fresh leaves
using qualitative
phytochemical
screening.
7. Antibacterial Lozada et 1 Journal Finding organic
Activity of al., (2021) sources of
Santan (Ixora antibacterial
coccinea) Leaf, activity that are
Cacao broadly
(Theobroma accessible,
cacao) Pod environmentally
Husk, and acceptable,
Betel Palm affordable, and
(Areca possess high
catechu) Seed antibacterial
Extracts efficacy
Against continues to be
Staphylococcu difficult,
s aureus. particularly in
 poor nations like
the Philippines.
In this work, the
antibacterial
efficacy of betel
palm (Areca
catechu) seed,
chocolate
(Theobroma
cacao), and
santan (Ixora
coccinea) leaf
extracts against
Staphylococcus
aureus was
evaluated.

Masagca et 105- Research This

8. Anti- al., (2020) 111 Article investigation
angiogenic examined the
properties of anti-angiogenic
“Makahiya”, properties of
Mimosa various
pudica L. concentrations
(Fabaceae) of mimosine,
aqueous root flavonoids,
extracts. tannins, etc.
from Mimosa
pudica L.
aqueous root
extract (ARE).
(Fabaceae) on
the developing
duck embryo's
chorioallantoic
membrane
(CAM).
Decoction,
grounding, and
air-drying were
used as the
extraction
techniques.
9. Antibacterial Lazarte et Article In this study, it
Activity of al., (2020) was determined
Guyabano, whether
Ulasimang guyabano,
 Bato, tsaang gubat,
Sambong, and sambong, and
Tsaang Gubat ulasimang bato
Leaf Extracts had any
against antibacterial
Common effects on
Drug-resistant common
Bacteria. Acta infections.
Medica Traditional
Philippina, . healers have
traditionally
used plants as
antimicrobials;
verifying these
practises may
result in the
discovery and
creation of
valuable herbal
medications.
10. Antibacterial Lazarte et Article In this study, it
Activity of al., (2020) was determined
Guyabano, whether
Ulasimang guyabano,
Bato, tsaang gubat,
Sambong, and sambong, and
Tsaang Gubat ulasimang bato
Leaf Extracts had any
against antibacterial
Common effects on
Drug-resistant common
Bacteria infections.
Traditional
healers have
traditionally
used plants as
antimicrobials;
verifying these
practises may
result in the
discovery and
creation of
valuable herbal
medications.
11. Antibacterial Lazarte et 17-21 Article n this study, it
Activity of al., (2020) was determined
Guyabano, whether
Ulasimang guyabano,
 Bato, tsaang gubat,
Sambong, and sambong, and
Tsaang Gubat ulasimang bato
Leaf Extracts had any
against antibacterial
Common effects on
Drug-resistant common
Bacteria. infections.
Traditional
healers have
traditionally
used plants as
antimicrobials;
verifying these
practises may
result in the
discovery and
creation of
valuable herbal
medications.
12. GREEN Paragas et 436- Journal Sambong
SYNTHESIZED al., (2020) 448 (Blumea
COPPER balsamifera)
NANOPARTICL leaves were
ES FROM used to extract
Blumea biocidal
balsamifera compounds that
LINN. LEAVES were effective
AND ITS against the
BIOCIDAL oriental fruit fly,
ACTIVITIES Bactrocera
dorsalis (Hendel)
(Diptera:
Tephritidae),
using rice wine,
rice wash, apple
cider vinegar,
and distilled
water as
solvents.
13. Philippine None Article Makahiya is a
Medical sparsely spiky
Plants. herb with many
Godofredo deflexed, bristly
Stuart / hairs that
StuartXchange spreads widely
and is half-
woody. Its
branched stems
can reach a
length of one
metre. Pinnae
and leaflets on
the leaves are
both incredibly
delicate and fold
when pressed.
Each petiole
typically has 4
digitately
arranged pinnae
that range in
length from 4 to
9 centimetres.
The leaflets are
sparsely bristly,
sessile, narrowly
oblong,
inequilateral, 1
to 1.5
centimetres
long, and pointy
at the tips. Long-
peduncled,
single, or two to
three in each
axil, the heads
have a diameter
of one
centimetre.
Pods have 3 to 5
one-sided joints
that break off
when they reach
maturity. They
are flat, slightly
recurved, and 1
to 2 centimetres
long. The upper
portion of the
flowers are red,
while the
filaments are
pink to lavender.
14. In vitro Cua (2018) Thesis The objective of
Antacid the current
Screening of study is to
the Aqueous assess I's in vitro
and Ethanolic antacid
Leaf Extracts properties.
of Ixora cockcea and M.
Coccinea using the
(Linn). and preliminary
Mimosa antacid test,
Pudica (Linn.). acid
neutralisation
capacity,
neutralising
effect, duration
of consistent
neutralisation,
and acid
buffering
capacity to
analyse pudica
ethanolic and
aqueous
extracts.
Additionally,
phytochemical
screening is
done, with an
emphasis on
how many
alkaloids are
present in plant
extracts.
15. Antioxidant K. Gonzales, 1-10 Journal This
and M. Gonzales investigation
Antibacterial & Bitacura was done to
Screening of (2018) evaluate M's
Makahiya antioxidant and
(Mimosa antibacterial
pudica L.) properties.
Collected from pudica, a
Three Sites in generalist
Baybay City, species, was
Leyte, collected from
Philippines . various locations
in Baybay City,
Leyte,
 Philippines
(including a
dumpsite, an
agricultural
region, and a
pasture area),
and these
activities were
related to the
soil biophysico-
chemical
features of the
locations. The
2,2-Diphenyl-1-
picrylhydrazyl
(DPPH) radical
scavenging
activity and disc
diffusion tests
were used to
examine the
antioxidant and
antibacterial
effects of the
bioactive
compounds
after they had
been extracted
using the
maceration
procedure and
95% ethanol as
the solvent.
16. Phytochemical Monroy and  Journal The antibacterial
and Limsiaco and antifungal
Antimicrobial (2016) potentials of the
Analysis of expressed juice
“Lupo” of "Lupo"
(Alternanthera (Alternanthera
sessilis sessilis) were
L.R.BR.). evaluated in this
study, and it is
probable that
these
phytochemicals
may have
nutritional and
therapeutic
 benefits. The
tests for
alkaloids,
steroids,
anthraquinones,
flavonoids, and
tannins were
performed on
the extracts
using the
guidelines in
Guevara's 2005
book, A
Guidebook to
Plant Screening:
Phytochemical
and Biological.
The experiment
made use of the
Kirby-Bauer
approach, which
involves a
minimum
inhibitory
concentration
(MIC) and
minimum
antibacterial
concentration
(MAC).
17. INHIBITORY Molina 150– Journal
ACTIVITY OF (2015) 158
MAKAHIYA
(Mimosa
pudica Linn)
LEAF EXTRACT
TO THREE
TEST
ORGANISMS.
18. Antibacterial Valle et al., 532- Article
activities of (2015) 540
ethanol
extracts of
Philippine
medicinal
plants against
multidrug-
resistant
 bacteria. 
19. ACUTE Nogodula Journal . This study's
DERMAL (2014) main focus is on
TOXICITY AND figuring out the
ANTIBACTERIA combined leaf
L ACTIVITY extracts of
SCREENING OF Makahiya
COMBINED (Mimosa pudica)
LEAF and Bayabas
EXTRACTS OF (Psidium
MAKAHIYA guajava) for
(Mimosa their
pudica) AND antibacterial
BAYABAS efficacy against
(Psidium Staphylococcus
guajava) aureus and
Pseudomonas
aeruginosa. For
the screening
study and the
main trial,
respectively,
dosages of 1000
mg/kg and 2000
mg/kg of the
combined
extracts were
used for the
Acute Dermal
Toxicity tests.
20. Blumea Pang et al., 9453- Article This article lists
balsamifera— (2014) 9477 the essential
A elements of
Phytochemical sambong
and (Blumea
Pharmacologic balsamifera).
al Review The entire plant,
its crude
extracts, as well
as its isolated
constituents,
exhibit a wide
range of
biological
activities,
including those
that are
antitumor,
 hepatoprotectiv
e, superoxide
radical
scavenging,
antioxidant,
antimicrobial
and anti-
inflammation,
anti-plasmodial,
anti-tyrosinase,
platelet
aggregation,
enhance
percutaneous
penetration,
wound healing,
anti-obesity, as
well as insect
and disease
resistant. Even
though a great
deal of
experimental
and biological
research has
been done,
some traditional
uses, like curing
rheumatism, still
need to be
supported by
scientific
pharmacological
studies.
21. In vitro Nogodula et Journal The rise of many
Antibacterial al., (2013) diseases could
Screening of put everyone's
Santol health at risk.
(Sandoricum Nevertheless,
koetjape the Philippines is
Merr.) Leaf endowed with
Crude Extract. abundant
natural
resources that
can be used to
treat illnesses.
One of them is a
Sandoricum
 koetjape
(Santol) in which
the antibacterial
action of fresh
and dried leaf
extracts against
bacterial strains
such as
Staphylococcus
aureus,
Staphylococcus
epidermidis,
Salmonella
typhimurium,
Methicillinresist
ant
Staphylococcus
aureus (MRSA)
ATCC 43300 and
isolate, Bacillus
cereus,
Escherichia coli
0157:H7, Listeria
monocytogenes,
and
Pseudomonas
aeruginosa were
the focus of this
study.

22. Phytochemical Nogodula Journal This study has

, Antibacterial (2012) motivated the
And researchers to
Mutagenic do
Analyses Of phytochemical
Commercially and
Available antimicrobial
Kalamansi screening of
(Citrofortunell Kalamansi juice.
a Microcarpa) A commercially
Fruit Extract available
Kalamansi fruit
extract was used
to assess the
levels of
alkaloids,
tannins, and
 saponin, while
antimicrobial
evaluation
methods
included the
Kirby-Bauer disc
diffusion
method,
minimum
inhibitory
concentration
(MIC), minimum
bactericidal
concentration
(MBC), and
potency tests.
23. Toxicological Nogodula Journal The B'laan tribe
and (2012) uses the
Antimicrobial medicinal plant
Evaluations of ekswater
Formulated (Mikania
Ointment cordata) to treat
from Eskwater wounds. It is an
(Mikania effective
cordata treatment for
Asteraceae) newly
Leaf Extract diagnosed, hard-
against to-treat
Trichophyton infections
mentagrophyt brought on by
es and Trichophyton
Methicillin- mentagrophytes
Resistant and methicillin-
Staphylococcu resistant
s aureus. Staphylococcus
aureus. This
study was
carried out to
evaluate the
acute dermal
toxicity,
antibacterial
activity,
Minimum
Inhibitory
Concentration
(MIC), potency
test with the
 standard drug,
and
mutagenicity
assay of
eskwater leaf
extract in order
to validate such
claims.
24. Xanthine Apaya et al., Article Chosen plant
oxidase (2011) species from the
inhibition of Philippines that
selected are traditionally
Philippine used for their
medicinal anti-
plants. inflammatory
extracts
characteristics
were looked
into to see if
they could stop
xanthine oxidase
in its tracks. The
extent of
Adenanthena
payonina,
Antegonon
leptopus,
Blumea
balsamifera, and
Calophyllum are
used to
suppress.Portula
ca, Gliricidia
sepium,
Michelia alba,
Cassia alata,
Cassia fistula,
Mimosa pudica,
and inophyllum
Tinosphora
rumphii,
Pogostemon
cablin, Solanum
tornum,
Olercea,
Pogostemon
cablin, and Vitex
negundo
 extracts were
measured by
taking into
account the rise
in absorbance at
295 nm that is
connected to
uric acid. It has a
connection to
gout.
25. Antibacterial Panganiban 289- Journal Theobroma
Activity of et al., 292 cacao Linn.) pulp
Cacao (2010) crude extract
(Theobroma was tested for
Cacao Linn.) antibacterial
Pulp Crude activity using
Extract the paper disc
Against diffusion
Selected method against
Bacterial a number of
Isolates. bacterial
isolates,
including
Staphylococcus
aureus ATCC
25923,
Escherichia coli
ATCC 25922,
and
Pseudomonas
aeruginosa ATCC
27853 in this
study. Using the
tube dilution
approach, it was
also possible to
estimate the
minimum
inhibitory
concentration
(MIC), minimum
bactericidal
concentration
(MBC), and the
biological
stability of cacao
against the test
pathogens.
 Additionally,
stability studies
were carried out
to see how pH
and
temperature
affected the
effectiveness of
cacao against
bacterial
isolates.
26. Roots of Balag-ey, et 23-35 Journal This established
Mimosa al., (2009) whether
pudica Linn phytochemicals
“Makahiya” as were present in
an alternative mimosa. pudica
treatment Linn and
against evaluated the
urinary tract remedial impact
infections. of its roots on
UTIs, or urinary
tract infections.
The study's ten
patients were
experimental
and control
groups received
the same
therapy, groups.
27. Phytochemical Racadio et 11-18 Journal The purpose of
and al., (2008) this
Microbiologica investigation is
l Testing of to determine
Makahiya the chemical
(Mimosa components
pudica Linn.) that are present.
Leaf Extract. in Makahiya and
examine its
potential for
microbes. It is
hoped that this
study would
serve as a
benchmark for
future research
on mahiya as a
complementary
medication.
 main objective
was to analyse
phytochemicals
and
The leaves of
the Makahiya
plant (Mimosa
pudica Linn) are
microscopic.
28. Phytochemical Racadio et 11-18 Journal The purpose of
and al., (2008) this
microbiologica investigation is
l testing of to determine
Makahiya the chemical
(Mimosa components
pudica linn.) that are present.
leaf extract. in Makahiya and
examine its
potential for
microbes. It is
hoped that this
study would
serve as a
benchmark for
future research
on mahiya as a
complementary
medication.
main objective
was to analyse
phytochemicals
and
The leaves of
the Makahiya
plant (Mimosa
pudica Linn) are
microscopic.
29. Screening of Parungao Journal Actinomycetes
Antibiotic- (2007) were examined
Producing for antimicrobial
Actinomycetes activity in this
from Marine, study after being
Brackish and isolated from
Terrestrial marine,
Sediments of brackish, and
Samal Island, terrestrial
Philippines. sediments in San
Isidro, Babak
 District, Island
Garden City of
Samal, Davao
del Norte. The
various
sediment
samples were
used to isolate a
total of 54
actinomycetes,
which were then
evaluated for
antagonistic
activity towards
Escherichia coli,
Staphylococcus
aureus, Candida
utilis, and
Aspergillus
niger.

Local Studies

Title Author/s Page/s Types of Summary and

literatures/studies how it is
related to your
topic
1. angiogenesis Supas & 40 Research Paper The goal of this
modulatory Camarillo study is to
activity of (2018) determine
makahiya whether
(Mimosa Makahiya
pudicalinn) (Mimosa
METHANOLIC leaf pudica Linn)
extracts using methanolic leaf
duck extract has the
embryochorioalla ability to
ntoic membrane modulate
(CaM) assay angiogenesis in
duck embryo
chorioallantoic
membrane
(CAM). The
 setups included
retinol as a
positive
control,
distilled water
as a negative
control, and
Makahiya
pudica
methanolic leaf
extract in
concentrations
of 10 mg/mL,
20 mg/mL, and
40 mg.
2. Antimicrobial Manalang et 25 Thesis In this study,
potential and al., (2017) the
phytochemical phytochemical
analysis of profile of
Mimosa pudica L. Mimosa pudica
(makahiya) L. was analysed
aqueous and in relation to its
methanolic leaf antibacterial
crude extracts. activity. On
Escherichia coli,
Staphylococcus
aureus,
Klebsiella
pneumoniae,
and Salmonella
enteritidis,
aqueous and
methanolic leaf
crude extracts
(Makahiya)
were used. A
two-part
experimental
investigation
that used six
treatments in
triplicates,
including a
positive control
(ciprofloxacin),
a negative
control (sterile
water), and
 aqueous and
methanolic leaf
crude extract of
Mimosa pudica
L. The study
also included
tests for
antimicrobial
susceptibility.
against the
aforementione
d four (4)
bacterial test
species at two
(2) different
concentrations.
3. The Medicinal Acio (2017). 7-12 Research Paper The purpose of
Prospects of the current
Makahiya investigation is
(Mimosa Pudica to determine
Linn) Plant. the medicinal
prospects of
the plant
Mimosa pudica
Linn. The
researcher
identified the
phytochemicals
present in the
plant using a
qualitative
analysis in
order to
achieve this
goal. Analysis
was done on
the ability of
the plant
extract to stop
the growth of
three different
types of
bacteria,
including
Staphyloccus
aureus, Bacillus
subtilis, and
Candida
 albicans.
4. SAMPLE Content Rien (2016) 42 Research Paper
ANTIMICROBIAL
ACTIVITY OF
HAGONOY,PANSI
T PANSITAN,
MAKAHIYA
AGAINST
MICROBES IN
PACKED FRUITS.
5. The antibacterial Alpuerto (2003) 1-2 Thesis/ This study
activity of Dissertation focused on
Mimosa pudica figuring out
Linn. (Makahiya) how
leaf extract antibacterial
against fresh Makahiya
Escherichia coli leaves were.
and Using 95% ethyl
Staphylococcus alcohol as the
aureus solvent,
extraction by
maceration was
used to prepare
the extractive
made from
fresh Makahiya
leaves. Once
obtained, the
extractive was
concentrated
until it was
alcohol-free.
The extract was
created using
33% Test
Solution and
100% Test
Extract. The
positive control
was 10 g of
Gentamicin
Sensi Disc.
Sterilised water
served as the
negative
control.