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Public Sessions

Sessions allow users to save snapshots of the Genome Browser and its current configuration, including displayed tracks, position, and
custom track data. The Public Sessions tool allows users to easily share those sessions that they deem interesting with the rest of the
world's researchers. You can add your own sessions to this list by checking the appropriate box on the Session Management page.

See the Sessions User's Guide for more information.

Sort by: Creation (newest first)

Show 10 entries Search: protein

Screenshot Session Properties

Description: This session highlights a single nucleotide change (G to A) with
pathogenic consequences found within FOXP2, a gene associated with human speech
and language comprehension. FOXP2's association with speech was discovered
through this single nucleotide change first witnessed in the "KE family"; A pedigree in
which almost half of the members for the past three generations have developed a
speech disorder called verbal dyspraxia. The OMIM track is enabled and has a marker
representing the nucleotide change found in the KE family pedigree. This G to A allele
change results in a codon that corresponds to a different amino acid, histidine instead
of the correct amino arginine (p.R553H), and results in a faulty protein which, as seen
in the KE family, causes verbal dyspraxia. Find the story in UCSC's education module:
https://genome.ucsc.edu/training/education
Author: education
Session Name: hg19_FOXP2p.R553H
Genome Assembly: hg19
Creation Date: 2022-05-15
Views: 95

Description: Highly conserved region in GRK4 gene. High PhyloP score for first and
second nucleotides of codons reflects amino acid conservation through evolutionary
time. Third base varies (wobble) because these amino acids have multiple codons --
the third base can be anything is free to diverge through time. PFAM track shows that
this is a functionally significant region (protein kinase). Find the story in UCSC's
education module: https://genome.ucsc.edu/training/education
Author: education
Session Name: hg19_wobble2
Genome Assembly: hg19
Creation Date: 2022-05-12
Views: 59

Description: This session shows a portion of BRCA2 (exon 11), a gene associated
with breast cancer. Two dbSNP tracks are enabled and mark known variants in the
region displayed. Red boxes represent variants that disrupt effective protein production
(missense), while green boxes indicate that the variant does not change the resulting
amino acid (synonymous). Some of these missense variants have pathogenic
consequences, causing breast cancer. Find the story in UCSC's education module:
https://genome.ucsc.edu/training/education
Author: education
Session Name: hg19_BRCA2variants
Genome Assembly: hg19
Creation Date: 2022-02-03
Views: 81

Description: This session shows TRPV3 which researchers believe is involved in our
ability to sense and detect warm temperature. Scripps Research Institute scientists
have demonstrated that mice lacking the TRPV3 protein have specific deficiencies in
:
 their ability to detect temperatures.
Author: brianlee
Session Name: skin_heat_sense
Genome Assembly: hg19
Creation Date: 2022-01-03
Views: 113

Description: Close-up view if transition zone between a coding and a non-coding

region of the virus. Note the High conservation in the PhyloP track in the protein-coding
region. Find the story in UCSC's education module:
https://genome.ucsc.edu/training/education
Author: education
Session Name: ebolav_pconserv
Genome Assembly: eboVir3
Creation Date: 2021-12-22
Views: 44

Description: Ebola virus VP24 gene with PhyloP track showing high conservation in
the protein-coding region among 160+ isolates. Find the story in UCSC's education
module: https://genome.ucsc.edu/training/education
Author: education
Session Name: ebolav_phylop
Genome Assembly: eboVir3
Creation Date: 2021-12-22
Views: 51

Description: Ebola virus genome showing vp24 gene region. The PhyloP track shows
that the 100+ strains of ebola and Marburg have conservation in the protein-coding
region of the gene. Pink color indicates a positive value above the display level in the
track. Find the story in UCSC's education module:
https://genome.ucsc.edu/training/education
Author: education
Session Name: ebolav_vp24
Genome Assembly: eboVir3
Creation Date: 2021-12-22
Views: 45

Description: Zoomed-in view of ebolavirus L protein showing serine codon in the

reference that is different in many islolates distantly related to it (lower part of figure).
Find the story in UCSC's education module:
https://genome.ucsc.edu/training/education
Author: education
Session Name: ebolav_codon
Genome Assembly: eboVir3
Creation Date: 2021-12-22
Views: 51
:
 Description: Full genome of ebola virus showing proteins in the top track and
conservation among several outbreaks in the lower tracks. Find the story in UCSC's
education module: https://genome.ucsc.edu/training/education
Author: education
Session Name: ebolav_mainsession
Genome Assembly: eboVir3
Creation Date: 2021-12-22
Views: 58

Description: Sessions shows part of spike protein on SARS-CoV-2 genome. One track
shows the reference amino acids for the spike protein. A custom track at the top shows
the location of two amino acids that are substituted by prolines to hold the protein in the
pre-fusion conformation. A track near the bottom shows the Moderna and
Pfizer/BioNtech vaccines with the two prolines substituted for lysine and valine of the
reference. The last rack shows current variants of concern (VoC). Reconfigure the
vaccine track to see the "different RNA bases" by clicking the gray button to the left of
track.
Author: Example
Session Name: wuhCor1_ProPro2
Genome Assembly: wuhCor1
Creation Date: 2021-08-04
Views: 259

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