Seat No.: _____ Enrolment No.

_____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph. - SEMESTER– 3 EXAMINATION – WINTER -2022

Subject Code: BP303TP Date: 17/02/2023

Subject Name: Biochemistry
Time: 10:30am to 01:30pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) What is bioenergetics? Discuss in detail concept of free energy. 06

(b) Write a note on high energy compounds & add a note on ATP –ADP cycle. 05
(c) What are proteins? Give classification of proteins. 05
Q.2 (a) Explain tricarboxylic acid cycle. 06
(b) Write a note on Oxidative phosphorylation. Add a note on inhibitors of 05
Oxidative phosphorylation
(c) Write a note on Glycogen storage disease. 05
Q.3 (a) Explain β-oxidation of palmitic acid. 06
(b) Explain ketone bodies formation with its regulations. 05
(c) Draw the Krebs-Henseleit cycle and enlist disorders of the cycle. 05
Q.4 (a) Write a detail note on catabolism of purine nucleotide along with the disorders 06
related to it.
(b) Write a detail note on translation process and its inhibition. 05
(c) Write a note on gout. 05
Q.5 (a) What is Replication? Explain the role of DNA polymerase, DNA ligase and 06
DNA helicase in the replication of prokaryotics.
(b) Describe the Watson and Crick Model of DNA Structure. 05
(c) Explain electron Transport Chain with neat & clean diagram. 05
Q. 6 (a) Explain factors effecting enzyme activity. 06
(b) Explain diagnostic applications of enzyme. 05
(c) Explain Michaelis–Menten equation. 05
Q.7 (a) Explain role of hormones in blood glucose level maintenance. Discuss in brief 06
about diabetes mellitus
(b) Write a short note on following metabolic disorders: Phenylketonuria, Black 05
urine disease and albinism.
(c) Discuss defective metabolism of lipids. 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph. - SEMESTER–III • EXAMINATION – SUMMER -2022

Subject Code: BP303TP Date: 06/09/2022

Subject Name: Biochemistry
Time: 02:30pm to 05:30pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Discuss β-oxidation of palmitic acid. 06

(b) Describe the mechanism of enzyme action. 05
(c) Write a note on glycogen storage disease. 05
Q.2 (a) Describe electron transport chain with its mechanism. 06
(b) Explain HMP shunt pathway. 05
(c) Comment on hormonal regulation of blood glucose level and describe diabetes 05
mellitus.
Q.3 (a) Explain the genetic code in detail. 06
(b) Define: (i) Allosteric enzyme (ii) Coenzyme (iii) Isoenzyme (iv) Uncoupler (v) 05
High-energy compounds
(c) Write a note on cori’s cycle. 05
Q.4 (a) Classify amino acids. Discuss the function of protein in biological system. 06
(b) Define: (i) Mutarotation (ii) Anomers (iii) Epimers (iv) Crabtree effect (v) 05
Limit dextrin
(c) Describe fatty liver and atherosclerosis. 05
Q.5 (a) Discuss in detail about purine ribonucleotide biosynthesis. 06
(b) Explain catabolism of phenyl alanine and tyrosine. 05
(c) Define ketone bodies. Discuss its formation and utilization. 05
Q. 6 (a) Write a note on TCA cycle with its energetics. 06
(b) Discuss in brief inhibitors of protein synthesis. 05
(c) Discuss the biological significance of ATP and cyclic AMP. 05
Q.7 (a) Write a note on DNA replication. 06
(b) Describe therapeutic and diagnostic applications of enzymes and isoenzymes. 05
(c) Explain catabolism of heme. 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph. - SEMESTER– 3 EXAMINATION – WINTER -2022

Subject Code: BP303TP Date: 17/02/2023

Subject Name: Biochemistry
Time: 10:30am to 01:30pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) What is bioenergetics? Discuss in detail concept of free energy. 06

(b) Write a note on high energy compounds & add a note on ATP –ADP cycle. 05
(c) What are proteins? Give classification of proteins. 05
Q.2 (a) Explain tricarboxylic acid cycle. 06
(b) Write a note on Oxidative phosphorylation. Add a note on inhibitors of 05
Oxidative phosphorylation
(c) Write a note on Glycogen storage disease. 05
Q.3 (a) Explain β-oxidation of palmitic acid. 06
(b) Explain ketone bodies formation with its regulations. 05
(c) Draw the Krebs-Henseleit cycle and enlist disorders of the cycle. 05
Q.4 (a) Write a detail note on catabolism of purine nucleotide along with the disorders 06
related to it.
(b) Write a detail note on translation process and its inhibition. 05
(c) Write a note on gout. 05
Q.5 (a) What is Replication? Explain the role of DNA polymerase, DNA ligase and 06
DNA helicase in the replication of prokaryotics.
(b) Describe the Watson and Crick Model of DNA Structure. 05
(c) Explain electron Transport Chain with neat & clean diagram. 05
Q. 6 (a) Explain factors effecting enzyme activity. 06
(b) Explain diagnostic applications of enzyme. 05
(c) Explain Michaelis–Menten equation. 05
Q.7 (a) Explain role of hormones in blood glucose level maintenance. Discuss in brief 06
about diabetes mellitus
(b) Write a short note on following metabolic disorders: Phenylketonuria, Black 05
urine disease and albinism.
(c) Discuss defective metabolism of lipids. 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph. - SEMESTER–III • EXAMINATION – SUMMER-2021

Subject Code:BP303TP Date: 31/08/2021

Subject Name: Biochemistry
Time: 02:30PM to 05:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B. Pharm. - SEMESTER–III • EXAMINATION – WINTER -2021

Subject Code: BP303TP Date: 19/02/2022

Subject Name: BIOCHEMISTRY
Time: 10:30AM to 01:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Write down electron transport chain and its mechanism. 06
(b) Write about formation and utilization of ketone bodies. 05
(c) Write down therapeutic and diagnostic applications of enzymes. 05
Q.2 (a) Define Carbohydrate. Discuss Classification and biological roles of 06
Carbohydrate.
(b) Write down biological significances of steroidal hormones. 05
(c) Write down biological significances of ATP and cAMP. 05
Q.3 (a) Write a note on HMP shunt and its significances. 06
(b) Write down biosynthesis and Catabolism of Purine nucleotide. 05
(c) Write about enzyme inhibitors with suitable examples. 05
Q.4 (a) Write about concept of free energy. Discuss endergonic and exergonic reaction. 06
(b) Define Lipids. Write down biological importance of lipids. 05
(c) Explain structure of DNA and RNA. 05
Q.5 (a) Discuss synthesis and significances of Dopamine, Noradrenalin and Adrenalin. 06
(b) Write about β-Oxidation of saturated fatty acid. 05
(c) Write down various steps in protein synthesis. 05
Q. 6 (a) Define Enzymes. Write down properties and IUB classifications of enzymes. 06
(b) Explain about Hyperuricemia and Gout diseases. 05
(c) Define gluconeogenesis. Discuss its pathway and significance 05
Q.7 (a) Write about various disorders of lipid metabolisms. 06
(b) Write a note on catabolism of heme. 05
(c) Discuss strucutre and biochemical functions of Co-enzymes. 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Pharm – SEMESTER-III • EXAMINATION – SUMMER -2020

Subject Code: BP303TP Date: 28-10-2020

Subject Name: BIOCHEMISTRY
Time: 2:30 PM TO 5:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define Carbohydrate. Discuss classification and biological role of 06

Carbohydrates.
(b) Write down biological significance of cholesterol. 05
(c) Write a detail note on structure of protein. 05
Q.2 (a) Describe the hexose monophosphate shunt. Write about its significance. 06
(b) Write down β-Oxidation of saturated fatty acid. 05
(c) Write down catabolism of Tyrosine. Discuss its metabolic disorders. 05
Q.3 (a) Write down biosynthesis of purine and pyrimidine nucleotides in briefs. 06
(b) Write about the process of replication of DNA. 05
(c) Explain about hormonal regulation of blood glucose level in body. 05
Q.4 (a) Write down biological significances of ATP and cyclic AMP. 06
(b) What are lipids? Classify lipids with example. 05
(c) Write a note on Genetic Code. 05
Q.5 (a) Define following terms: 06
1. Enthalpy
2. Entropy
3. Redox Potential
(b) Explain formation and utilization of ketone bodies. 05
(c) Write a note on Protein synthesis. 05
Q. 6 (a) Write down electron transport chain (ETC) and its mechanism. 06
(b) Write about structure of RNA. 05
(c) Discuss structure and biochemical functions Coenzymes 05
Q.7 (a) Define enzymes. Discuss properties and classifications of enzymes. 06
(b) Write about urea cycle and its disorder. 05
(c) Discuss synthesis and significance of Dopamine. 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph.- SEMESTER–III • EXAMINATION – WINTER -2020

Subject Code:BP303TP Date: 03/03/2021

Subject Name: Biochemistry
Time: 02:30PM TO 04:30PM Total Marks: 54
Instructions:
1. Attempt any THREE questions from Q-1 to Q-6.
2. Q.7 is compulsory to attempt.
3. Make suitable assumptions wherever necessary.
4. Figures to the right indicate full marks.

Q.1 (a) Discuss Aerobic Glycolysis with energetic. 06

(b) Discuss the Synthesis of Glucose from Non-Carbohydrate sources. 05
(c) Write a note on citric acid cycle & explaining its amphibolic nature. 05
Q.2 (a) Discuss components and reactions of the electron transport chain. 06
(b) Define oxidative phosphorylation and discuss inhibitors of oxidative 05
phosphorylation.
(c) Write a note on Glycogen Storage Disease. 05
Q.3 (a) What are carbohydrates? Give classification of carbohydrates with examples & 06
function of it.
(b) (1) Differentiate Saturated and Unsaturated Fatty Acids. 05
(2) Define (i) Iodine number (ii) Saponification number (iii) Acid number
(c) Define bioenergetics and discuss concept of free energy. 05
Q.4 (a) Discuss β-oxidation of fatty acids. 06
(b) What do you mean by ketone bodies? Discuss its formation and utilization. 05
(c) Discuss in detail Cholesterol Biosynthesis. 05
Q.5 (a) Write in brief Genetic code. Add a note on various inhibitors for protein 06
synthesis.
(b) Define Enzyme. Give the brief classification of enzymes with suitable 05
examples.
(c) Define Enzyme inhibition. Explain reversible and irreversible inhibition of 05
enzyme.
Q. 6 (a) Write about reaction of Krebs-Henseleit cycle and enlist disorders of the cycle. 06
(b) Describe in detail transamination and deamination reactions for amino acids 05
metabolism.
(c) Write in brief about atherosclerosis and jaundice. 05
Q.7 (a) Discuss in detail about purine biosynthesis. 06
OR
(a) Discuss the Watson and Crick model of DNA structure. 06
OR
(a) Describe in brief DNA replication. 06

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM - SEMESTER– 3 EXAMINATION – SUMMER -2019

Subject Code: BP303TP Date: 01-06-2019

Subject Name: Biochemistry
Time: 02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Enlist unsaturated fatty acids and discuss oxidation of omega-3 fatty acid 06
(b) Discuss amphibolic nature of citric acid cycle. 05
(c) Explain β-oxidation of fatty acid 05
Q.2 (a) Explain the properties and identification tests of carbohydrate 06
(b) Define: Iodine number, Saponification number, Acid number, 05
Rancidity, Mutarotation
(c) Write a note on TCA cycle 05
Q.3 (a) Discuss importance of Cori’s cycle 06
(b) Discuss the Synthesis of Glucose from Non-Carbohydrate sources 05
(c) Write a note on regulation of enzyme activites 05
Q.4 (a) Write a note on galactose and fructose 06
(b) Write a note on cholesterol biosynthesis 05
(c) Discuss the transport mechanism across cell membrane 05
Q.5 (a) Describe the structures and function of mucopolysaccharides 06
(b) Describe the Watson and Crick Model of DNA Structure 05
(c) Discuss enzyme kinetics in brief and its mechanism of action 05
Q. 6 (a) Explain Metals and Vitamins as Co-enzyme and their Significance 06
(b) Write a note on protein synthesis and inhibitors. 05
(c) Write a note on Lipid Storage Diseases 05
Q.7 (a) Explain the genetic code with its characteristics 06
(b) Explain in detail the process of RNA synthesis. 05
(c) Describe significance of melatonin and dopamine. 05

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Seat No.: _____ Enrolment No. _____________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.Ph. - SEMESTER–III • EXAMINATION – WINTER -2019

Subject Code: BP303TP Date: 19/11/2019

Subject Name: BIOCHEMISTRY
Time:10:30AM TO 01:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define and classify carbohydrate with suitable examples. Also explain 06
biological role of carbohydrates.
(b) Define bioenergetics and give relationship between free energy, enthalpy and 05
entropy and redox potential.
(c) Draw flow chart of Glycolysis – Pathway and discuss its energetics and 05
significance
Q.2 (a) Write a note on Electron transport chain (ETC) and its mechanism 06
(b) Explain Oxidative phosphorylation & its mechanism. 05
(c) Give brief note on β-Oxidation of saturated fatty acid. 05
Q.3 (a) Discuss Biological significance of cholesterol and conversion of cholesterol 06
into bile acids and vitamin D.
(b) Give a brief note on De novo synthesis of fatty acids 05
(c) Give a detail note on urea cycle and its disorders 05
Q.4 (a) Write a brief note on catabolism of heme and discuss hyperbilirubinemia 06
(b) Give brief note on Protein synthesis and inhibitors 05
(c) Draw the Structure of DNA and RNA and discuss their functions. 05
Q.5 (a) Give detail on regulation of enzymes. 06
(b) Define and classify enzyme. 05
(c) Discuss Enzyme inhibitors with examples 05

Q. 6 (a) Give Therapeutic and diagnostic applications of enzymes 06

(b) Give hormonal regulation of blood glucose level. 05
(c) Write in brief Gluconeogenesis- Pathway. 05
Q.7 (a) Define energy rich compounds and give its classification and biological 06
significance.
(b) Give a brief note on Uncouplers. 05
(c) Write a brief on Enzyme kinetics 05

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Seat No.: ________ Enrolment No.______________

GUJARAT TECHNOLOGICAL UNIVERSITY

B.PHARM – SEMESTER – 3- EXAMINATION –WINTER - 2018

Subject Code:BP303TP Date: 06/12/2018

Subject Name: Biochemistry
Time:10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Classify carbohydrates. Describe the structure and functions of 06

polysaccharides.
(b) Define following: 05
i) Anomers ii) Enantiomers iii) Epimers iv) Invert sugar v) Mutarotation
(c) Write a note on TCA cycle with energetics. 05
Q.2 (a) Define following: 06
Co-enzymes ii) Essential amino acid iii) Co-factor
Allosteric site v) Apoenzyme vi) Feedback inhibition of enzyme
(b) Discuss synthesis and significance of biological substances 5-HT and 05
dopamine.
(c) Discuss jaundice in detail. 05
Q.3 (a) Discuss in detail β-oxidation of saturated fatty acids with energetics. 06
(b) Write a note on formation and utilization of ketone bodies. 05
(c) Classify energy rich compounds and give significance of ATP. 05
Q.4 (a) Explain catabolism of phenylalanine and tyrosine. 06
(b) Discuss the role of hormones in blood sugar homeostasis. 05
(c) Define oxidative phosphorylation. Describe in detail substrate level 05
phosphorylation.
Q.5 (a) Give biosynthesis and significance of Cholesterol. 06
(b) Discuss following diseases: 05
i) Atherosclerosis ii)Albinism
(c) Explain catabolism of heme. 05
Q. 6 (a) Discuss competitive and non competitive enzyme inhibiton. 06
(b) Discuss Michealis-Menten kinetic model for enzymes. 05
(c) Explain in detail about the enzyme involved in biological oxidation. 05
Q.7 (a) Discuss Watson and Crick model of DNA structure. 06
(b) Explain structure and functions of different types of RNAs. 05
(c) Discuss purine nucleotides catabolism and Gout disease. 05

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