Al-Quds University

Faculty of Medicine

Medical Education Unit

Programme Evaluation & Quality Assurance Committee

Second Semester
Academic Year 2022/2023

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 Respiratory System

Course Number Credit Hours Sequence

6100221 4+1 Second Semester / Second Year
Course Coordinator
E.mail

Course Description:
This multidisciplinary five credit-hour module provides a comprehensive and integrated
coverage of anatomy, histology, physiology, embryology, pathophysiology, microbiology,
biochemistry and pharmacology relating to the respiratory system is discussed in an integrated
manner. The course includes lectures, practical sessions, small group discussion and clinically
oriented seminars will be part of this module to enhance self-directed learning.

General Objectives
Aim 1: Identify and describe the anatomical and histological appearance of different parts of the
respiratory system and their relations to physiological functions of the system.

Aim 2: Define the most common types of respiratory diseases and their treatment (Asthma,
COPD, Respiratory infections, respiratory tumours)

Intended learning outcomes of the course (ILOs)

A. Recall of knowledge and Understanding:

A1- Identify and describe the macroscopic appearance of different parts of respiratory system
(upper and lower parts).
A2- Microscopic appearance of different microscopic cells that compose different parts of
respiratory system.
A3- Description of normal embryological development of the respiratory system and the
common congenital abnormalities can take place.
A4- Describe and understand the physiology of respiratory system (inhale, exhale processes
and acid base balance).
A5- Describe normal bacteria reside the respiratory system (normal flora). Recognition and
characterization of microorganisms that cause infection of the respiratory system, their
pathogenicity and methods of identification.
underlying behavior, motivation, and emotions.
A6- Understand and discuss different respiratory diseases with emphasis asthma, COPD and
lungs tumors.
A7- Understanding the mechanisms of action, pharmacokinetics, uses and adverse effects of
commonly used drugs in the treatment of common types of respiratory diseases.

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A8- Understanding the factors and phases of asthma development include the main
immunoglobulin mediates the disease (IgE).

B- Intellectual Skills
By the end of the course, students will be able to:
B1- Integrate the basic anatomical & physiological facts of respiratory system with clinical data.
B2- Correlate functional alterations of common pathological conditions and diseases of
respiratory system with clinical data.
B3- Use problem solving skills in a variety of practical and clinical situations related to
respiratory
System.
B4- Acknowledge the relationship of respiratory system with other body systems like the central
nervous and the cardiovascular systems.

C. Professional and Practical Skills

By the end of the course, students will be able to:
C1- Determine and choose of what clinical laboratory tests must be done, and other clinical
investigations include radiography of suspected diseased tissue.
C2- Interpret and analyse microbiology lab results and other laboratories data.

D. General and Transferable Skills

By the end of the course, students will be able to:
D1- Respect superiors, colleagues and any other members of the health profession.
D2- Communicate ideas and arguments effectively.
D3- Work constructively and cooperatively within a team.
D4- Practice self and peer evaluation & Manage time effectively in respiratory System.

Course Summary:

Discipline Lectures Practical CBL*

Anatomy 6+1 1
Physiology 16 1
Histology 2 1
Biochemistry 2
Pathology 6 1
Microbiology 9 2
Immunology 2
Pharmacology 8
Multidisciplinary* 2
*
Clinical lectures 2
TOTAL 54 6 2
*Case Based Learning

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Academic Staff

Discipline Academic Staff

Anatomy Dr. Mostafa Nakhala “1section”
Dr. Motaz Bsharat “3 sections”
Dr. Mohammad Baker Abu Snieneh “2 sections”
Embryology Dr. Mohammad Baker Abu Snieneh “all sections”
Physiology Dr. Amer Rahhal & Dr. Safaa Abdulghani 3
sections each
Biochemistry Dr. Kifaya Alqam & Dr. Rula Abdulghani 3
sections each
Histology & Pathology Dr. Ghassan Balousha 4 sections & Dr. Marwan
Qubaja 2 sections
Microbiology Dr. Ibrahim Abbasi & Dr. Murad Ibrahim 3 sections
each
Immunology Dr. Suhail Hamdan “ all sections”
Pharmacology Dr. Afnan Atallah & Bilal Saleh3 sections each

Methods of Teaching:

A. Theoretical Sessions (TS):

Lect. no. Lecture Title Department
Overview of respiratory system Anatomy
1
The nose & Paranasal Sinuses
The pharynx Anatomy
2+3
The larynx
Thoracic wall Anatomy
4+5
Diaphragm and respiratory muscle
6 Trachea, Bronchial tree Pleura & lungs Anatomy
7+8 Histology of respiratory system Pathology
9 Embryology Anatomy
10+11 Types of Respiration, Functions of Respiratory Passageways Physiology
12+13 Pulmonary Ventilation: Mechanics of Ventilation Physiology
14 Overview of respiratory infections Microbiology
15+16+17 Bacterial Infections Microbiology
18+19 Thoracic wall Diaphragm and respiratory mechanism Physiology
20+21 Pulmonary Circulation Physiology
22+23 Transport of Oxygen and Carbon Dioxide in the Blood Physiology

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 24+25 Exchange of Gases between Blood Capillary and Tissues Physiology
26+27 Oxygen hemoglobin saturation curve Physiology
Contribution of respiratory system to Acid Base Balance.
28+29 Oxidative stress and free radicals: link to lung diseases Biochemistry
30 Atelectasis, ARDS and Diseases of vascular origin Pathology
31+32 Viral Infections Microbiology
33+34 Regulation of Respiration Physiology
Obstructive lung disease
35+36 Pathology
Restrictive lung disease
37+38 + 39 Drugs Used for Bronchial Asthma & COPD Pharmacology
40+41 Fungal and Parasitic Infections Microbiology
42 Histamine and H-1 Anti-Histamines Pharmacology
Drugs Used for Cough and Expectorants
43+44+45 Pharmacology
Drugs used to treat allergic rhinitis & common cold
46 Mycobacterium Tuberculosis Microbiology
47+48 Pulmonary Infections Pathology
49 Drugs Used for Tuberculosis Pharmacology
50 Lung Tumors Pathology
51+52 Immunological Diseases of Respiratory System Immunology
53 Medical Aspects of Respiratory Diseases Medicine
54 Surgical Aspects of Respiratory Diseases Surgery

B. Practical Session (PS):

1- Anatomy of Respiratory system
2- Respiration volumes and capacities, Effect of asthma, dead space, hypoxia
and hypercapnia on maximum breathing capacity and vital capacity
(Physiology)
3- Histology of Respiratory System
4- Pathology of Respiratory System
5- Identification of respiratory pathogens (Microbiology)
6- Throat cultures (Microbiology)

C. Evidence Based Medicine (EBM) and Small Group Discussion (Case Based
Learning)
1. Evidence Based Medicine Sessions (EBM)
Please write a 500-words review of the following subjects, use the following design:
o Introduction: define the basic disorder terms.
o Body: explain the evidence found in the articles for the subject
o Conclusion
o References (Use Endnote for citations).
o Plagiarism is strictly prohibited, any project with more than 15% Plagairism will
be marked zero.

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 Topic

1 Reactive oxygen species (ROS) and lung cancer

2 Oxidative stress in asthma

3 Glutathione and inflammatory disorders of the lung

The role of pulmonary surfactant in the treatment of respiratory
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distress syndrome in COVID-19.
5 Pulmonary compliance and non-elastic resistance during exercise. 

6 Using of Fluoroquinolone as first line treatment for pneumonia

7 Using of passive Immunization in RSV treatment

8 Role of peripheral neuropathy in development of respiratory failure.

Bronchio-alveolar lavage in diagnosis of malignant and infectious lung
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diseases.
Role of genetics in development of bronchial asthma.
10

11 Mitochondrial stress and lung diseases

Relevance of Glutathione Transport and Its metabolism in lung
12
disease
13 Antioxidant and treatment of COPD

14 Azithromycin use in COPD patients

15 Biological treatments for asthma

Empiric therapy for community-acquired pneumonia
16

2. Case Based Learning (CBL)

Case report related to the respiratory system, and preparation of a small presentation.
 Case presentation
 Review of the basics of the disease
 Investigations
 Treatment

Topic
Session 1 1 Asthma

2 Chronic Obstructive Pulmonary Disease

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 3 Metastatic Lung Cancer
Session 2 4 Cystic Fibrosis

5 Pneumonia

6 Upper Respiratory Tract Infections

Assessment Plan

A) Assessment Methods

Formative Assessment
It is a part of learning process and is not included in the module allocated marks. The goal of
a formative assessment is to monitor student learning to provide ongoing feedback that can
help students identify their strengths and weaknesses and target areas that need work. It also
helps faculty recognize where students are struggling and address problems immediately and
can be used by instructors to improve their teaching and by students to improve their
learning.
- Quizzes
- Draw a concept map in class to represent their understanding of a topic
- Submit one or two sentences identifying the main point of a lecture
- One-minute papers on a specific subject matter
- Lesson exit tickets to summarize what students have learnt

Summative Assessment including

- MCQs, extended matching, short answer questions and case scenarios (Assessment of
knowledge and understanding)
- Objective Structured Practical Exam – OSPE (Assessment of knowledge, understanding and
general skills)

B) Time Schedule and Grading System

Attendance / Activities: 7%

Lab Assessment: 18 %
Activities & Quizzes 8%
Final Exam (OSPE) 10 %
EBM / CBL: 10 %
End of Module, Comprehensive Final Exam: 65 %
Total 100 %

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Course Schedule:

Week Discipline
First
Second
Third
Fourth
Fifth Written Exams + OSPE

Recommended text books and Atlases:

1- Anatomy
- Clinical anatomy by systems, R.S. Snell, (latest edition)
- Grants Atlas of Anatomy or any other reasonable colored atlas of Human
Anatomy
- Before we are born. By K.L. Moore and T.V.N. Persaud, (latest Edition)
2- Physiology:
- Textbook of Medical physiology. By Guyton and Hall, Latest Edition.
3- Biochemistry:
- Textbook of Biochemistry with clinical correlations. Thomas M. Devlein (latest
edition)
4- Pharmacology
- Pharmacology, Lippincott’s Illustrated Review, (latest edition)
5- Histology & Pathology
- Basic Histology, by L.Carlos Junqueira, Jose Carneiro, Bobert O. Kelley, (latest
edition)
- Basic Pathology, Kumar, W.B. Saunders, (latest edition)
6- Microbiology & Immunology
- Review of Medical Microbiology and Immunology, Levinson, W. (latest
edition)
- Immunology: A short course (Seventh edition 2015). Richard Coico and
Geoffry Sunshine.Wiley Blackwell.

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