Epic Pigmentation Solutions

Developed by Zein Obagi, MD

Innovative Skin Health Science
Under the guidance of Dr. Zein Obagi, ZO Skin Health, Inc., has
developed a wide spectrum of therapeutic treatments and daily
skincare solutions that create and maintain healthy skin. Based
on the latest scientific advances in skin therapy technologies,
these products and protocols help physicians provide continuous
skin health for all skin types, genders, and ages.
ZO Multi-Therapy HQ System
®

949.988.7524 www.zoskinhealth.com

ZO Non-HQ
®

Hyperpigmentation System

ZO Innovative Pigmentation Treatments for All Skin Types

®

ZO Skin Health, Inc., and Dr. Obagi have no business relationship with Obagi Medical Products, and Obagi Medical
Products does not sell or endorse using any ZO product. “ZO” is a registered trademark of ZO Skin Health, Inc. 800104 3/14
Breakthrough Advancements in Pigmentation Treatments by Zein Obagi, MD
Texture Control ZO Signature Peels

Created by Zein Obagi, MD, ZO® Pigmentation Systems are the ultimate solution for treating a wide range
of skin disorders using synergistic ZO® hydroquinone and ZO® non-hydroquinone treatments. Strength & Vitality

ZO Multi-Therapy
®

ZO Non-Hydroquinone
®

Dr. Zein Obagi’s Principles of

Hydroquinone System Hyperpigmentation System ZO Skin Health Restoration
®
Deep Renewal/Repair

First-Line Treatment Alternative Treatment

Getting Skin Ready

STABILIZATION Texture Control

Getting Skin Ready
Cleansing, toning and controlling
ZO Signature Peels

oil to improve the epidermis

by Zein Obagi, MD Hydrating and Calming

Texture and Color Control
Sun Protection Strength & Vitality Correcting through bleaching and exfoliation
The New Benchmark for
Hand/body Renewal Texture Control ZO Signature Peels
Week 1 Week 2 Week 3 Week 4 Week 5 Week 6
Strength and Vitality
Pigmentation Treatments, Stabilization aids repair of barrier
Prevention and Maintenance Deep Renewal/Repair
Strength & Vitality function and DNA

The process of stabilization helps improve and Hydrating and Calming

control skin cellular function, which enables skin Getting Skin Ready
Accelerating hydration from within
to resist the negative effects of external and
Deep Renewal/Repair
to minimize reactions
internal elements.
Hydrating and Calming
Sun Protection
Deep Renewal and Repair
ZO Medical solutions provide physicians a choice
®
Hand/body Renewal
Texture Control Stimulating and blending to improve the dermis
ZO Signature Peels

Skin Health Restoration, Conditioning, Pigmentation Stabilization, Maintenance, of hydroquinone and non-hydroquinone based
Getting Skin Ready

and Stabilization and Prevention regimens that treat a variety of skin conditions. Sun Protection
With an emphasis on bleaching, stabilization, and With an emphasis on stabilization and blending, the ZO ® Hydrating and Calming Broad spectrum protection through topical
The ZO Non-Hydroquinone System is used after agents and externally-applied melanin
® Sun Protection Strength & Vitality

blending, the ZO HQ system is safer and more effective

®
non-HQ system encompasses novel formulations and an Hand/body Renewal

for all skin types. effective protocol to control and stabilize melanocytes, completing the ZO Multi-Therapy Hydroquinone
®

• The ideal skin health restoration system

preventing additional discoloration. System or when HQ resistance or side effects
Hydrating and Calming
Hand and Body Renewal
• An alternative when HQ is contraindicated, patients are are present.
Hydrating and Calming
Sun Protection
Sun Protection Deep Renewal/Repair
Stimulating and blending to correct
• Treats any hyperpigmentation condition Hand/body Renewal

allergic to HQ, or patients are non-responsive to HQ

Hand/body Renewal
and protect skin
including melasma
• Avoids the risk of patients developing HQ resistance
• Innovative approach to correct sun damage
and side effects Hydrating and Calming ZO Signature Peels
®

• Everything needed to control treatments and

Sun Protection
Getting Skin Ready
A variety of personalized in-office
• Helps maintain the results after HQ treatments Hand/body Renewal Texture Control ZO Signature Peels
optimize results and home treatments
Hydrating and Calming
Sun Protection

Hand/body Renewal
Strength & Vitality

Innovating the Science of Skin Health

Dr. Zein Obagi continues to redefine and advance the science of skin
health restoration. Under his guidance, ZO Skin Health, Inc. is providing Deep Renewal/Repair

physicians with today’s most innovative skincare technologies, protocols

By Zein Obagi, M.D. and education programs.
Getting Skin Ready
ZO Multi-Therapy Hydroquinone System
®

Skin Health Restoration, Conditioning, and Stabilization Treatment ZO Multi-Therapy Hydroquinone System New Hydroquinone Facts and
®

The ZO Multi-Therapy Hydroquinone System is a safer and more effective approach to

® Recommendations all Skin Health
Professionals Should Know
1 Bleaching
treat a wide variety of pigmentation disorders using bleaching, stabilization, and blending. MELAMIN Skin Bleaching & Correcting Crème, HQ USP, 4%
™

Stimulates epidermal • Bleaches existing hyperpigmentation

• Stops new melanin formation
by Zein Obagi, MD
improvement
Skin Health Restoration • Blocks free radicals
Novel formulations and an effective
protocol to improve skin health.
2 Exfoliation GLYCOGENT Exfoliating Accelerator
™

• Resurfaces the epidermis

Accelerator
Skin Conditioning Improves skin
• Stimulates epidermal renewal

Used before and after procedures to • Anti-inflammatory and antioxidant benefits

surface texture
improve outcomes and extend results.

3 Epidermis Ossential Daily Power Defense

®

Hyperpigmentation Treatment Stabilization

• Repairs and restores skin barrier function
“Based on my years of experience with
• Helps protect and repair damaged DNA
Effective for a wide range of skin types. Improves skin renewal hydroquinone treatments, all skin
• Anti-inflammatory and antioxidant benefits
and strengthening
Week 1 Week 2 Week 3 Week 4 Week 5 Week 6 health professionals should understand
Texture Improvement the following cautions, risks and

4 Blending MELAMIX Skin Lightener & Blending Crème, HQ USP, 4%

™

recommendations.”
Treats dry, dull, and rough skin.
Improves dermal • Mixed with Tretinoin to normalize melanin distribution
stimulation • No bleaching effect
Sun Damage Repair and renewal • Anti-inflammatory benefits Hydroquinone Treatment Cautions
Exfoliation, DNA repair, antioxidants Hydroquinone must be used only under
and protection to strengthen the skin. Tretinoin USP, 0.1% and 0.05% a physician’s supervision
• Treats medical conditions (general skin repair) HQ is a valuable agent, but it carries risks
that require a physician’s care.

ZO GSR Medical System (Getting Skin Ready)

® ™ Avoid concentrations greater than 4.0%
High concentrations of HQ can cause
This system is the essential first step to achieve successful results melanocytes to rebound causing an increase
with all ZO therapeutic treatments.
®
in melanin production.

Normal to Oily Skin Normal to Dry Skin Usage should never exceed 4 to 5 months
HQ is an inflammatory agent and can become
FOAMACLEANSE ™
NORMACLEANSE ™
an allergenic, increasing hyperpigmentation.
 ild surfactants remove surface impurities
•M  leansing system
•C
Visible Results in 6 Weeks

GETTING SKIN READY

 ipid replenishers combat skin dryness
•L  eplenishes moisture balance
•R
Sun protection is essential
HQ increases photosensitivity, which can
Cleanses, corrects, exfoliates, stabilizes melanocytes, and protects all skin types.
accelerate UV damage.
VITASCRUB ™
Offects Exfoliating Polish
®

•M  echanical stimulation without irritation  echanical stimulation

•M
• Niacinamide for natural epidermal renewal without irritation Pulsed-HQ Regimens – Increased
 ntioxidant benefits
•A Efficacy with Reduced Risks
CEBATROL ™

Consider sequencing HQ treatments with ZO®

 esigned to reduce sebum
•D BALATONE ™

non-HQ therapy to increase efficacy while

 nti-acne medication and anti-
•A  alming, pH balancing
•C reducing the risks of HQ side effects.
inflammatory benefits and hydrating
• Limit HQ therapy to 3 or 4 months
• Reduce HQ dosage before completing therapy
Broad Spectrum Sun Protection • Allow the skin to stabilize after HQ therapy
PROTECT

Maximum protection against OCLIPSE-C SPF 50

™ • Resume HQ treatments only if needed
Before Treatment After Treatment UVA, UVB and HEV  road protection with a UVA/UVB sunscreen
•B
ZO Multi-Therapy
®
• F or patients not responding to HQ,
Hydroquinone System and HEV protection with natural melanin use the ZO® Non-HQ System
ZO Non-Hydroquinone Hyperpigmentation System
®
Pigmentation Stabilization, Maintenance and Prevention
This innovative ZO Non-Hydroquinone System is used following the ZO Multi-Therapy
® ®
System, or when HQ is not indicated. It is designed to even skin tone without bleaching
and help stimulate collagen and elastin production for a firm, smooth appearance.
Visible Clinical Results
Clarifies and evens skin color and tone.
Before Treatment
ZO Non-Hydroquinone Hyperpigmentation System ZO 3-STEP PEEL
® ® ™
®
A Truly Universal Peel
1 Blending BRIGHTENEX Skin Brightener & Correcting Crème
™
• Non HQ melanocyte activity stabilization
Improves epidermis The ZO® 3-Step Peel can replace any
and targets the stages • Restores even distribution of melanin
of skin discoloration • Anti-inflammatory and antioxidant benefits
exfoliating peel for all skin types and ages.
Epidermal Stimulation This highly innovative peel developed by
This innovative system uses novel Dr. Zein Obagi, is an in-office peel that
2 Epidermis Ossential Daily Power Defense
®
bioengineered ingredients to support provides unmatched control of epidermal
• Repairs and restores skin barrier function
barrier function, DNA repair, and anti-
Stabilization and dermal stimulation.
• Helps protect and repair damaged DNA
Improves skin renewal
inflammatory activity, while reducing and strengthening • Anti-inflammatory and antioxidant benefits • P
 rovides texture improvement
UV light damage and minimizing and anti-aging benefits
3
skin reactions. Deep Renewal RETAMAX Active Vitamin A Micro Emulsion
™
• Improves sun-damaged pigmentation
Dermal activation • Retinol micro-emulsion helps epidermal • Restores soft, smoother skin
Skin Brightening and stimulation stabilization and dermal stimulation
with Hydroquinone • Improves texture with anti-aging benefits
• Minimal patient downtime
This system is for hyperpigmentation
4 Hydration &
or melasma in patients who are not RESTORACALM Soothing Recovery Crème
™
Use monthly or as needed to enhance
• Anti-irritation and anti-inflammatory benefits
improving with HQ or are allergic to HQ. Calming ZO® Hyperpigmentation Treatments
• Helps restore epidermal and dermal hydration
Stimulates the skin’s
Maintaining the Results of natural recovery process by hyaluronic acid up-regulation STEP 1.
Hydroquinone Treatments Peel Solution
After completing a course of hydroquinone, ZO GSR Medical System (Getting Skin Ready)
® ™
An exclusive blend of exfoliants:
this regimen can be used as a skin health This system is the essential first step to achieve successful results salicylic acid, trichloracetic acid
with all ZO therapeutic treatments.
®
and lactic acid removes
maintenance system. It is designed to
the outermost layers of skin.
restore a natural even-blended skin tone. Normal to Oily Skin Normal to Dry Skin
•A
 cid cocktail with cofactor
• Strong blending FOAMACLEANSE ™
NORMACLEANSE ™
for self neutralization
 ild surfactants remove surface impurities  leansing system
GETTING SKIN READY
• Stabilizes melanocytes •M •C
• Prevents skin discoloration  ipid replenishers combat skin dryness
•L  eplenishes moisture balance
•R STEP 2.
• Maintains even skin tone VITASCRUB ™
Offects Exfoliating Polish
® Retinol Crème 6%
•M  echanical stimulation without irritation  echanical stimulation
•M An effective collagen regulation
• Niacinamide for natural epidermal renewal without irritation agent that stimulates skin for
 ntioxidant benefits
•A maximum benefits.
CEBATROL ™
 esigned to reduce sebum
•D •P
 otent Retinol for epidermal
BALATONE ™
 alming, pH balancing
•C
and dermal stimulation
 nti-acne medication and anti-
•A
inflammatory benefits and hydrating •A
 nti-inflammatory and
antioxidant benefits
Broad Spectrum Sun Protection
STEP 3.
PROTECT Maximum protection against OCLIPSE-C SPF 50 ™
Calming Crème –
UVA, UVB and HEV  road protection with a UVA/UVB sunscreen
•B
and HEV protection with natural melanin
Post Procedure Relief
Used after the peel solution
and retinol creme.
ZO 3-STEP PEEL – After Treatment
® ™
•A
 dvanced anti-inflammatory
SUPPORT
Supports ZO Non-Hydroquinone
®
ZO 3-STEP PEEL
® ™
and anti-irritant properties
After Treatment
ZO® Non-Hydroquinone Hyperpigmentation Treatments,  xfoliating peel with dermal stimulation
•E •H
 ydrates to restore
Hyperpigmentation System for all skin types supports epidermal and dermal restoration moisture balance