15-Aug-21

LIQUID CRYSTALS
 Liquid crystals (LCs) can be defined as a state of matter that have properties
Cosmetic Emulsions Based between those of a conventional liquid and solid crystal.

 Liquid crystal flow like a liquid but its molecules may be oriented in a crystal
like way.
 There are three types of liquid crystal which are:

Thermotropi
By: c Liquid
Crystal
Assoc. Prof. Dr. Mohd Zul Helmi Rozaini

Metallotrop Lyotropic
ic Liquid Liquid
Crystal Crystal

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Benefits of liquid crystals in

Lyotropic Liquid Crystals formulations
 Consist of two or more components that exhibit liquid crystalline properties in  High stability against coalescence and creaming
certain concentration ranges.

 Lyotropic liquid crystal occurs with increasing concentration of surfactants  Bind water, prolonging skin hydration
solutions.

 Below are three structure phases of lyotropic liquid crystalline:  Bring structure of emulsions , creating an aesthetically
pleasing skin feel

 Create a spreadable film on the skin, enhancing water

resistance and modify behavior of water and oil soluble
actives.

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Liquid Crystal Concepts

 Currently there are two lyotropic liquid crystal systems
for cosmeceutical applications.

 Both systems are able to form lamellar phase at low

concentrations.

multilayers of
lamellar liquid
crystals
OLEOSOMES
produce a
Lyotropic liquid viscoelastic gel
phase.
crystal systems
produce a gel
HYDROSOMES network in the
continuous phase

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 15-Aug-21

What Are Oleosomes? Oleosomes

 The seeds of many plants species which store oils.
 Oleosomes are a form of liquid crystal, in which the
 They are oil spheres sizing 0.5 to 5 micrometers, a thin liquid crystals surround oil droplets.
membrane made of phospholipids and specific
proteins termed "oleosins".  Liquid crystal phase which build-up by diffusion of oil
phase into water.
 Oleosomes are capable of emulsifying a variety of oil
phase ingredients in formulations with an effective
HLB.  Diffusion from the oil droplet (=oleo)

 Oleosomes are by nature excellent cosmetic  Oil droplets surrounded by multilamellar liquid
moisturizers as well as powerful emulsifiers. crystalline phases.

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HYDROSOMES
 Hydrosome are surfactant stabilized aqueous
droplets.
 micron-sized aqueous droplets.
 Lamellar gel network build-up in continuous water
phase.

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EMULSION
Emulsions structure
 Emulsions are systems consisting of two or more liquid immiscible phases.
 Emulsions often contain a surface active agent which has two Oil in Water (O/W): Oil Water in Oil (W/O): Water
 main functions:
droplets dispersed in water droplets dispersed in oil
 (1) to decrease the interfacial tension between phases; thereby enabling
easier formation of the emulsion, and Complex (multiphase)
 (2) to stabilize the dispersed-phase against coalescence once it is formed emulsions

Emulsions can be classified into two broad groups: simple emulsions and
multiple emulsions.
W/O/W O/W/O
water
oil

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Rheology in Emulsion Sensory

 Emulsions exhibit highly varied rheological behavior that is useful and fascinating
 The stratum corneum consists of lamellar liquid
 An emulsion's macroscopic constitutive relationships between the stress and strain crystalline structures.
depend strongly on its composition, microscopic droplet structure, and
interfacial interactions.

 By controlling the droplet volume fraction, an emulsion can be changed from a

 There are obvious similarities between the natural
simple viscous liquid at low volume fraction to an elastic solid having a biological skin lipid system and the submicroscopic bi-
substantial shear modulus at high volume fraction
molecular membranes of oil-in-water skincare
 knowledge of the rheological properties is required for the design, selection, and products
operation of the equipment involved.

 Rheological studies can provide useful information on the stability and

microstructure of emulsions

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THANK YOU =)

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