Monday, 16 August 2021

Federal University of Technology, Owerri

Semester: Harmattan
Department: Public Health
Session: 2020/2021
Title of Course: Immunology and Immunization
Course Code: PUH 415
Continuous Assessment Test 1 (CAT) for week 1 to week 3

1. Nonspecific host defences that exist prior to exposure to antigen is called: a) acquired
immunity b) Innate immunity c) Adaptive immunity d) all of these
2. Innate immunity is also called: a) familial b) genetic c) inborn d) all of these
3. Innate immunity involves all except: a) anatomic barriers b) phagocytic c)
inflammatory mechanisms d) antibody production
4. First line of defence include: a) skin b) mucus c) lysozyme secretion d) all of these
5. Skin prevents pathogen entry: a) dead cells of the skin outer layer prevents pathogen
entry b) skin secretes oil by sebaceous gland that makes surface acidic c) skin secretes
sweat by sudoriferous gland that makes surface acidic. d) all of these
6. Stomach clear out pathogens by a) secreting HCL b) secreting digestive enzymes c)
both a & b d) none of these
7. Vaginal bacteria symbionts like lactobacilli prevents pathogen by: a) producing lactic
acid thereby reducing pH b) secreting antibiotics c) secreting toxins d) none of these
8. Bodies’internal defence or second line of defence include a) phagocytes b) fever c)
interferons d) all of these
9. The functions of macrophages include a) phagocytosis b) antigen presenting cells c)
cytokine production d) all of these
10. Kupfer cells are macrophages found on: a) lung b)bone c) nephrons d) liver
11. Neutrophils are: a) phagocytes b) short lived leucocytes c) all of these.
12. Tissue damage caused by wound or invading pathogens organisms induces a complex
sequence of events collectively known as: a) opsonization b) phagocytosis c)
inflammation d) none of these
13. Antiviral glycoproteins released by living cells in response to viral attack and induce a
viral resistant state to neighbouring cells is called as: a) natural killer cells b)
complement system c) interferons d) phagocytes
14. Complement component C3 is cleaved by: a) C3b b) C3b C3a c) factor B d) factor D
15. The membrane attack complex in the complement pathway consists of : a) C3b3b, Bb
b) C5b, C6,C7,C8,C9 c) colicins d) properdin
16. Complement component C3b: a) directly injures bacteria b) is an anaphylatoxin c) is
chemotatic d) is the inactive form of C3 d) opsonizes bacteria
17. A complement component that is strongly chemotactic for neutrophils: a) C3 b) C3b
c) C5a d) C5b e) C9
18. The classical and alternative pathways meet at complement component: a) C3 b) C4
c) C4b d) C5 e) factor D
19. The ability to ward off disease through body defences is called: a) resistance b)
immunity c) protection d) adaptation
20. Which class of antibody can cross the placenta? a) IgA b) IgD c) IgE d) IgG e) IgM