Biology 1819 V2 Past Paper

IFYBI002 Biology
THE NCUK INTERNATIONAL FOUNDATION YEAR
IFYBI002 Biology
Examination
2018-19
Examination Session Time Allowed

Semester Two 2 hours 40 minutes
(including 10 minutes reading time)
INSTRUCTIONS TO STUDENTS
SECTION A Answer ALL questions. This section carries 40% of the exam
marks.
SECTION B Answer 3 questions ONLY. This section carries 60% of the

exam marks.
The marks for each question are indicated in square brackets [ ].
• Answers must not be written during the first 10 minutes.

• Graph paper will be provided.
• An approved calculator may be used in the examination.
• Show ALL workings in your answer booklet.
• Examination materials must not be removed from the examination room.
DO NOT OPEN THIS QUESTION PAPER UNTIL INSTRUCTED BY THE

INVIGILATOR
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IFYBI002 Biology
NCUK NCUK NCUK NCUK NCUK NCUK NCUK NCUK NCUK NCUK NCUK
Please ignore this sheet

IFYBI002 Biology
Section A
Answer ALL questions. This section carries 40 marks.
Question A1
For questions A1 a) to e), write down the correct answer (there is only
one correct answer for each question).
a) The bond formed between two adjacent water molecules is: [1]
i. a hydrophobic interaction
ii. a hydrogen bond
iii. an ionic bond
iv. a covalent bond
b) The bond between two monosaccharides is: [1]
i. a disulphide bond
ii. an ester bond
iii. a glyosidic bond
iv. a peptide bond
c) Figure 1 shows part of a molecule.
Figure 1
H
C N
O
The bond shown in Figure 1 between N - H and N - C-O is: [1]
i. a disulphide bond
ii. an ester bond
iii. a glyosidic bond
iv. a peptide bond

IFYBI002 Biology
d) The type of reaction that forms an ester bond is: [1]
i. condensation
ii. hydrolysis
iii. oxidation
iv. reduction
e) The tertiary structure of a protein can be maintained by: [1]
i. disulphide bridges
ii. hydrogen bonds
iii. hydrophilic interactions
iv. all of the above
Question A2
Figure 2 shows an organelle from a human muscle cell.
Figure 2
P
a) Name the organelle shown in Figure 2. [1]
b) Identify the parts labelled P, Q and R of the organelle shown in

Figure 2 above. [3]
c) Briefly explain why muscles cells contain a large number of this type of
organelle. [2]
d) Name one other type of cell that would require large numbers of this type
of organelle. [1]
Section A continues on the following page.

IFYBI002 Biology
Question A3
Figure 3 shows the Krebs cycle.
Figure 3
acetyl CoA
citrate
X
oxaloacetate
X
Z
malate
-ketoglutarate
Y succinate
Z
W
Q
a) Identify molecules W, X, Y and Z in the above Figure. [4]
b) State where the Krebs cycle takes place in the cell. [1]
c) Describe how acetyl CoA is derived for use in the Krebs cycle. [3]

IFYBI002 Biology
Question A4
Figure 4 shows a section of mRNA that codes for the structural protein collagen:
Figure 4
GG*C CCC CCG GGC CCC CCG GGC
Table 1 shows the mRNA codes for the amino acids used in protein
synthesis:
Table 1
a) What is meant by a triplet code? [1]
b) Use Table 1 to translate the mRNA in Figure 4 into the collagen amino acid
sequence. [1]
c) An insertion mutation adds an adenine to the position marked with * on

Figure 4 so the codon becomes GGA.
Use Table 1 to translate the mutated mRNA into an amino acid sequence. [1]
d) Explain the effect that an insertion mutation has on the amino acid
sequence of collagen. [2]

IFYBI002 Biology
Question A5
Figure 5 shows a cross section of a human heart.
Figure 5
Y
X
a) Describe the journey of blood from point X to point Y on Figure 5. [3]
b) Briefly explain what is meant by a double circulatory system. [1]

IFYBI002 Biology
Question A6
Figure 6 shows an experiment set up to measure osmosis.
Figure 6
capillary tube
glucose solution
beaker of distilled water
thistle funnel
partially permeable
membrane
A student set up the apparatus as shown in Figure 6. He added 20 cm3 of a

1% glucose solution to the thistle funnel and sealed it with visking tubing
which is a partially permeable membrane. The thistle funnel was lowered into
a beaker containing distilled water at 25°C and the position of the glucose
solution in the capillary tube was recorded. The apparatus was left set up in
this way, and the student recorded the position of the glucose solution in the
capillary tube every 5 minutes for 30 minutes.
The results are shown in Table 2.
Table 2
Time Distance glucose
(minutes) solution moved (mm)
0 0
5 11
10 30
15 48
20 57
25 63
a) Explain why the student should have repeated the experiment at least
three times. [2]
b) Plot the data in Table 2 in a suitable form. [4]
c) Explain why the level of glucose solution in the capillary tube rises. [3]
d) By drawing a line on your plot:
i. predict the results if the temperature in the beaker had been

increased to 30°C. [1]
ii. Explain why you chose this line. [1]
Section B begins on the following page.

IFYBI002 Biology
Section B
Answer 3 questions. This section carries 60 marks.
You are encouraged to use labelled diagrams in any question to help make your
answers clearer. In some questions diagrams are required.
Question B1
a) Describe the structure of the cell surface membrane and explain why it is
referred to as a fluid mosaic. [6]
b) Give an account of the arrangement and function of the membrane

system in THREE of the following:
i. mitochondria;
ii. chloroplast;
iii. nucleus;
iv. Golgi apparatus;
v. endoplasmic reticulum. [ 14 ]
Question B2
a) Give an account of the events that take place during DNA replication. [ 15 ]
b) Briefly explain the significance of the work of Meselson and Stahl in the
replication of DNA. [5]
Question B3
a) Explain the importance of meiosis in gamete production. [6]
b) Give an account of the hormonal control of the menstrual cycle. [ 14 ]
Question B4
a) Give an account of the process of gene cloning using bacterial cells. [ 10 ]
b) Give some examples where gene cloning has been useful in the production
of medical and industrial substances. [5]
c) Describe the inheritance and effects of a sex-linked genetic condition, for

example haemophilia.
Note: You may use another example other than haemophilia in your
answer. [5]

IFYBI002 Biology
Question B5
a) Draw and label a stoma showing the detailed structure of the associated
specialised cells, and state where these are found in plants. [5]
b) Describe the movement of water molecules, in plants, from the soil to the
stomata. [ 10 ]
c) Explain how stomata and their associated cells regulate water loss in a [5]
plant.
This is the end of the examination.

IFYBI002 Biology
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IFYBI002 Biology

THE NCUK INTERNATIONAL FOUNDATION YEAR

Examination Session Time Allowed

SECTION B Answer 3 questions ONLY. This section carries 60% of the

The marks for each question are indicated in square brackets [ ].

• Answers must not be written during the first 10 minutes.

DO NOT OPEN THIS QUESTION PAPER UNTIL INSTRUCTED BY THE

V2 1819 © 2019 Northern Consortium UK Ltd Page 1 of 12

Please ignore this sheet

V2 1819 © 2019 Northern Consortium UK Ltd Page 2 of 12

ii. a hydrogen bond

iii. an ionic bond

iv. a covalent bond

b) The bond between two monosaccharides is: [1]

ii. an ester bond

iii. a glyosidic bond

iv. a peptide bond

c) Figure 1 shows part of a molecule.

The bond shown in Figure 1 between N - H and N - C-O is: [1]

ii. an ester bond

iii. a glyosidic bond

iv. a peptide bond

V2 1819 © 2019 Northern Consortium UK Ltd Page 3 of 12

d) The type of reaction that forms an ester bond is: [1]

e) The tertiary structure of a protein can be maintained by: [1]

ii. hydrogen bonds

iii. hydrophilic interactions

iv. all of the above

Figure 2 shows an organelle from a human muscle cell.

a) Name the organelle shown in Figure 2. [1]

b) Identify the parts labelled P, Q and R of the organelle shown in

Section A continues on the following page.

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Figure 3 shows the Krebs cycle.

Section A continues on the following page.

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GG*C CCC CCG GGC CCC CCG GGC

a) What is meant by a triplet code? [1]

c) An insertion mutation adds an adenine to the position marked with * on

Section A continues on the following page.

V2 1819 © 2019 Northern Consortium UK Ltd Page 6 of 12

Figure 5 shows a cross section of a human heart.

a) Describe the journey of blood from point X to point Y on Figure 5. [3]

b) Briefly explain what is meant by a double circulatory system. [1]

Section A continues on the following page.

V2 1819 © 2019 Northern Consortium UK Ltd Page 7 of 12

Figure 6 shows an experiment set up to measure osmosis.

beaker of distilled water

A student set up the apparatus as shown in Figure 6. He added 20 cm3 of a

The results are shown in Table 2.

b) Plot the data in Table 2 in a suitable form. [4]

d) By drawing a line on your plot:

i. predict the results if the temperature in the beaker had been

ii. Explain why you chose this line. [1]

Section B begins on the following page.

V2 1819 © 2019 Northern Consortium UK Ltd Page 8 of 12

b) Give an account of the arrangement and function of the membrane

a) Explain the importance of meiosis in gamete production. [6]

b) Give an account of the hormonal control of the menstrual cycle. [ 14 ]

a) Give an account of the process of gene cloning using bacterial cells. [ 10 ]

c) Describe the inheritance and effects of a sex-linked genetic condition, for

V2 1819 © 2019 Northern Consortium UK Ltd Page 9 of 12

This is the end of the examination.

V2 1819 © 2019 Northern Consortium UK Ltd Page 10 of 12