PROTECTION

LEPTOSPIROSIS MADE SIMPLE

Leptavoid®–H
can be administered at
the same time as your
HELP PROTECT YOUR CATTLE Bovilis® BVD
vaccine*
AGAINST BOTH UK STRAINS

DOUBLE PROTECTION**
* To animals of 8 months of age or older
** For the active immunization of cattle from 1 month of age against
Leptospira interrogans serovar hardjo (L. hardjo Prajitno) and Leptospira
borgpetersenii serovar hardjo (L. hardjo Bovis). To reduce shedding of
Leptospira interrogans serovar hardjo in urine. To improve herd
fertility when infertility is diagnosed as caused by Leptospira hardjo.
 UK OVERVIEW
58% of dairy farms and 33% of beef farms tested
positive for leptospirosis1.
In the UK, two strains of leptospirosis have been
identified – Leptospira interrogans serovar hardjo
and Leptospira borgpetersenii serovar hardjo 2.

If you don’t know the disease status of

your farm then speak to your vet about the
diagnostic tests available.

HEL P PROTECT YO UR CAT T LE AG AIN ST BOT H U K S T R AINS

 RISK TO YOUR CATTLE
In some cases the effects of leptospirosis can be dramatic, such as with a
recent outbreak in Ayr where the herd experienced a sudden onset drop in milk
production3.
In many cases, however, the underlying effects can
go un-noticed but cause huge financial losses. In a
Conception to first service
study looking at 529 cows in 5 herds4: 60%

50%

40%

»» Conception to first service rate was 30%

significantly reduced in infected cows 46%

30%
20%

»» For a 100 cow herd* this could mean 10%

0%
18 less cows in calf Clean cows Infected cows

* For a 100 cow herd, optimum bull ratio/AI, over 3 breeding cycles (9 weeks)

HEL P PROTECT YO UR CAT T LE AG AIN ST BOT H U K S T R AINS

 RISK TO YOU AND YOUR STAFF
Cattle farmers are at particular risk of contracting leptospirosis5 from the urine of
infected cattle, which may result in6:

»»Protracted flu-like symptoms

»»Some cases – liver and kidney failure

HEL P PROTECT YO UR CAT T LE AG AIN ST BOT H U K S T R AINS

 VACCINATION
Vaccination remains an important control measure and continues to be effective at
reducing the incidence of clinical disease7 and the risk of infection:

»»Infected herds
- Reduces urinary shedding and improves fertility
»» Non-infected (naïve herds)
- Prevents harmful effects if the disease entered the farm

HEL P PROTECT YO UR CAT T LE AG AIN ST BOT H U K S T R AINS

 LEPTAVOID®-H – LEADING THE WAY
Leptavoid®-H is the UK’s leading leptospirosis vaccine8 and the ONLY one:

»» Licensed to protect against BOTH UK strains

- Leptospira interrogans serovar hardjo
- Leptospira borgpetersenii serovar hardjo
»» Licensed to improve herd fertility where infertility is
caused by L. hardjo:
- 69% improvement in overall conception rate for
infected farms9
»» Approved to be given at the same time as a vaccine for BVD
(at different injection sites)*:
- Proven safety and efficacy of combination
- Reduced cattle handling, improving on-farm efficiency
* To animals of 8 months of age or older

HEL P PROTECT YO UR CAT T LE AG AIN ST BOT H U K S T R AINS

 RISK FACTORS
» Buying in stock with an unknown disease status
» Using a bull of unknown disease status
» Grazing near waterways
» Grazing with sheep

HEL P PROTECT YO UR CAT T LE AG AIN ST BOT H U K S T R AINS

 RECOMMENDED VACCINATION PROTOCOL
WITH LEPTAVOID®-H
It is important your herd is fully protected against bovine leptospirosis before Spring
turnout as, at grass, uninfected cattle are exposed to the urine of infected animals.

New vaccinators
New vaccinators require 2 doses
1 DOSE
st
2 DOSE
nd

6-8 weeks 2 weeks 4-6 weeks apart and the annual booster
before turnout before turnout
TURNOUT prior to turnout.
Annual Boosters
Natural service also spreads leptospirosis
2 weeks so remember to vaccinate the bull.
before turnout

HEL P PROTECT YO UR CAT T LE AG AIN ST BOT H U K S T R AINS

UK leptospirosis vaccines:
LEPTAVOID®-H
Licensed to protect against both UK strains
Licensed to improve herd fertility
Developed from a UK isolate of L.hardjo
Can be given at the same time as Bovilis BVD
Proven reduced urinary shedding
Use medicines responsibly.
For more information visit www.noah.uk/responsible
References:
1. BeefCheck and DairyCheck data, October 2013 – March 2015
2. Ellis, W.A. et al. (1998), Res Vet Sci, 44, p375-379
3. 2015, Milk drop due to leptospirosis in dairy cows, Veterinary Record, 7
March, p247-250
4. Williams, P. (1996), World Buiatrics
5. Health and Safety Executive. (2015) Leptospirosis. [Online] Available
from: http://www.hse.gov.uk/agriculture/zoonoses-data-sheets/
leptospirosis.pdf [accessed 16/11/15]
6. NHS Choices. (2015) Leptospirosis. [Online] Available from: http://www.
nhs.uk/conditions/leptospirosis/pages/introduction.aspx
7. UK Zoonoses Annual Report. (2014). Non Statutory Zoonoses Annual
Report [Online], available from: https://www.gov.uk/government/
publications/non-statutory-zoonoses-disease-surveillance-reports-2014
[accessed 16/11/15]
8. GfK data, MAT August 2015
9. Dhaliwal et al. (1996), Vet Record, 138, p334-335
77540/DEC15/IGN
Vaccine S
Leptavoid®-H is a vaccine containing Leptospira interrogans serovar hardjo
204 (inactivated). Legal category: POM-VPS . Contact your veterinary
surgeon or animal health professional for further information and advice.
Bovilis® BVD is a vaccine containing BVD virus strain C86.
Legal category: POM-V .
Bovilis BVD is only available via your veterinary surgeon from whom advice
should be sought. For information regarding side effects, precautions,
warnings and contra-indications please refer to the datasheet at
www.noahcompendium.co.uk.
Leptavoid-H and Bovilis BVD are the property of Intervet International
B.V. or affiliated companies or licensors and are protected by copyrights,
trademark and other intellectual property laws. Copyright © 2013 Intervet
International B.V. All rights reserved.
Further information is available from:
MSD Animal Health Walton Manor, Walton, Milton Keynes MK7 7AJ
Tel: 01908 685685 Fax: 01908 685555 Email: vet-support.uk@merck.com
www.msd-animal-health.co.uk