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Science, Technology, and Society Socio-emotional Skills - Learners have a sense

Prelims Review of belonging to a common humanity, sharing


values and responsibilities and holding rights.
- Interactions between science and technology
- Learners show empathy,
and social, cultural, political, and economic
solidarity and respect for differences and
contexts which shape and are shaped by them;
diversity.
specific examples throughout human history of
scientific, and technological developments.” Behavioral Skills - Learners act effectively and
CHEd CMO 20 s. 2013 responsibly at local, national and global
contexts for a more peaceful and sustainable
world.

“In the face of an alarming trend toward


discrediting scientific consensus and restricting
scientific discovery, we might ask instead: can
we afford not to speak out in its defense?"

Global Citizenship (GC) & Global Citizenship


Education (GCED)

● GC described: “a sense of belonging to a


broader community, beyond national
boundaries, that emphasizes our common
humanity and draws on the interconnectedness
between the local and the global, the national
and the international.” (UNESCO, 2014)

● GCED’s 4 pillars: “learning to know”,


“learning to do”, “learning to be”, “learning to Something to ponder…
live together” (UNESCO, 1996). What is the purpose of our life in this world?
Why are we here?
What is the goal of our work and all our efforts?
GCED & Education for Sustainable What need does the earth have of us?
Development (ESD) (UNESCO, 2013)

Key conceptual dimensions of GCED and ESD 17 Sustainable Development Goals (SDGs) by
the United Nations Member States
Cognitive skills - Learners acquire knowledge,
understanding and critical thinking about global A shared blueprint for peace and prosperity for
issues and the interconnectedness/ people and the planet.
interdependency of countries and different
populations.
An urgent call for action by all countries PHILOSOPHY OF SCIENCE
(developed and developing) in a global
• Philosophy means "love of wisdom."
partnership.
• It is made up of two Greek words, philo,
It is recognized that ending poverty and other
meaning love, and sophos, meaning wisdom.
deprivations must go hand-in-hand with
strategies that improve health and education, Why We Need Philosophy?
reduce inequality, and spur economic growth –
all while tackling climate change and working to • Philosophy helps teachers to reflect on key
preserve our oceans and forests. issues and concepts in education.

• usually through such questions as:


– What is being educated?
– What is the good life?
– What is knowledge?
– What is the nature of learning?
– And what is teaching?

• PHILOSOPHERS - Philosophers think about the


meaning of things and interpretation of that
meaning.

Science Philosophical Problems

Ethical (What is the nature of VALUES?)

the study of values in human behavior or the


study of moral problems: e.g., (1) the rightness
and wrongness of actions, (2) the kinds of things
which are good or desirable, and (3) whether
actions are blameworthy or praiseworthy.
Threats in achieving any goals -Explores the nature of values
Social Theories: Two Categories
Social Darwinism Ethics: study of human conduct and examines
Social Exchange Theory moral values

Aesthetics: values beauty, nature, and aesthetic


experience (often associated with music, art,
Examples of Societal Cases to be resolved by literature, dance theater and other fine arts)
STS:
Epistemological (What is the nature of
Shortage of sustainable water KNOWLEDGE?)
Illegal wildlife trade Is the study of knowledge. In particular,
epistemology focuses on how we come to
Science in the Philippines
acquire knowledge and what types of limits through dreams, visions, and
there are to our knowledge. In other words, preexisting theories.
how do we know what is true? It is sense • Rejects the notion that facts are neutral and
experience vs. reason. objective.
• Theories are confirmed, not proven, yet every
- Logic is a key dimension to epistemology
instance that lends support corroborates the
Two kinds of logic theory.

Deductive: General to specific


Falsificationism
Inductive: Specific facts to generalization • Also rejects the context of discovery.
Metaphysical (What is the nature of REALITY?) • Confirmation of hypothesis is not enough.
• No specific number of confirmations
the study of what is really real. Metaphysics will make any hypothesis true.
deals with the so-called first principles of the • A body of science must be falsifiable.
natural order and "the ultimate generalizations • The notion of scientific progress for the
available to the human intellect.”; laws, falsificationist rests on the premise that
causation, explanation scientific theories are tentative.
-concerned with reality and existence
Conjecture and Refutation
Subdivided into two categories • Science must continue to progress through an
open quest to put existing theories to the test,
Ontology: What is the nature of existence
allowing preconceived notions of “facts,”
Cosmology: Origin and organization of the
whatever they may be, up to scientific criticism
universe
and refutation.
• Thomas Kuhn famously published The
Structures of Scientific Revolutions in
Key concept: Science is based on facts.
1962, a publication that brought
Inductivism previous theories in the history and
• Inductivism proposes and rests on a common philosophy of science into a whole new
understanding of the laws of the universe; there context.
are laws of nature, uniformities that govern • Coined the term “paradigm.”
these laws.
• Facts are observable, and that theories should
be derived from these facts by observation. “Normal Science” versus “Revolutionary
• Observation using the senses. Science”
• Seeing is believing. It is in this period of revolutionary science that
• Observable facts are objective. theories are checked, previously held
formulations are re-analyzed and possible
Hypothetico-deductivism refutations are generated, for a new paradigm,
• Rejects the context of discovery. or paradigm shift to occur.
• asserts that “facts” are not always
observable.
Solving problems is scientific progress.
• Facts have come to scientists not by
observation but rather by accident,
Scientific Method Internal Consistency (across items)

1) ASK A PROBLEM – problem • The consistency of the measurement


2) DEFINE PROBLEM STATEMENT – itself.
research
• Do you get the same results from
3) CONSTRUCT THE HYPOTHESIS –
different parts of an experiment that
hypothesize
are designed to measure the same
4) TEST THE HYPOTHESIS – experiment
thing?
5) COLLECT THE DATA – analyze
6) REPORT THE RESULT – interpret Interrater Reliability (across
researchers)

• The consistency of a measure across


Qualitative Data
raters or observers.
Diary accounts, in-depth interviews, documents,
• Do you get the same results when
focus groups, case study research, and
different people conduct the same
ethnography, open-ended surveys
experiment?
- Provide a deep understanding of how people
perceive their social realities, and in
consequence, how they act within the social Validity
world
Validity refers to how accurately a method
Quantitative Data measures what it is intended to measure. If
research has high validity, that means it
Laboratory and field experimentations, rating
produces results that correspond to real
scales, closed survey questions such as “Yes” or
properties, characteristics, and variations in
“No” which can have numerical categories
the physical or social world.
- Statistics help turn quantitative data into
Note: High reliability is one indicator that a
useful information that are crucial for decision
measurement is valid. If a method is not
making Scientifically objective and rational
reliable, it probably isn’t valid.

Face Validity
Reliability • the extent to which a measurement
method appears “on its face” to
Reliability refers to how consistently a method
measure the construct of interest. E.g.
measures something. If the same result can be
IQ test
consistently achieved by using the same
Construct Validity
methods under the same circumstances, the
• used to ensure that the measure is
measurement is considered reliable.
the actual measure of what it is
Test-Retest Reliability (across time) intended to measure (i.e. the
construct), and not other variables. E.g.
• The consistency of a measure across self-esteem questionnaire
time. Content Validity
• Do you get the same results when
your repeat the experiment?
• The extent to which the measurement
covers all aspects of the concepts being
measured. E.g. Comprehension test
Criterion Validity
• The extent to which the result of a SCIENTIFIC REVOLUTION THROUGHOUT THE
measure corresponds to other valid HISTORY OF MANKIND
measures of the same concept. E.g.
survey
Discriminant Validity
• the extent to which scores on a
measure are not correlated with
measures of variables that are
conceptually distinct. E.g. Self-esteem

Paleolithic (2M-10,000BC)
- Hand axe from Europe
- Hammerstone from Majuangou, China
- Bone Needle

Neolithic (10,000BC)
Always remember CRAAP!!! - Agriculture, society, house
- Neolithic grinding stone
Currency: Is the information current? - Neolithic sickle
Relevance: Is the information important?
Authority: Who is the author/publisher/sponsor Ancient (3000BC)
of the news? - Sumerian: Plow, Cuneiform
Accuracy: Is the information supported by - Chinese: Gun powder, Great Wall, Tea & Silk
evidence? Does the author cite credible - Egyptian: Papyrus
sources? Is the information verifiable in other - Romans: Codex or Books
places? Purpose: What is the purpose of this
news? Industrial Civilization
- Combustion engine
- Thomas Edison; phonograph
- Henry Ford; automobile
- John Hall and Bryan Dorkin; commercial
canning factory, England, 1813
- Alexander Graham Bell; telephone in 1876
- Brothers Orville and Wilbur Wright: Airplane in
1903
- Peter Durand: Tin can, 1980

The Anthropocene (Present) – the rise of the


human empire
- The era in which human activity has been the
dominant influence on climate and the Global Carbon Emissions from Fossil Fuels
environment. (1900-2014)

• Scientists in the Soviet Union appear to have


used the term “Anthropocene" as early as the
1960s to refer to the Quaternary, the most
recent geological period.
• The term was widely popularized in 2000 by
atmospheric chemist Paul J. Crutzen, who
regards the influence of human behavior on
Earth's atmosphere in recent centuries as so
significant as to constitute a new geological
time.
Plastic Use
Issues that have identified the Anthropocene: • Plastics, initially developed in the 1900s, have
grown rapidly since the 1950s, and we now
Nuclear Weapons produce 500 million tons a year.
• Warfares have left their mark on geology. • Sediments containing plastics will be a clear
• When the first nuclear weapon was detonated sign of the Anthropocene.
on 16 July 1945 in New Mexico

Fossil Fuels
• Burning fossil fuels mark Anthropocene age.
• Current rates of carbon emission are thought
to be higher than at any time in the last 65
million years.

Carbon Emissions

Changed Geology
• A patch of rainforest destroyed changes the
future of Earth’s geology.
• Over 50% of Earth’s land area have been
transformed for our own purpose
• Deforestation, farming, drilling, mining,
Global Greenhouse Gas Emissions by Gas landfills, dambuilding and coastal reclamation
are all having widespread effects on human’s sense or ability and augments it and
sedimentary processes. makes it more powerful. So for example, I wear
• Disrupting how layers of rock are laid down, contact lenses or glasses; that is a technology
which will be detectable thousands of years in that enhances my human ability of vision and
the future. makes it better.”
Use of Fertilizers
• Our attempts to feed an increasing population The Essence of Technology
will leave clear indicators, too. • Science and Technology: responsible for the
• Levels of nitrogen and phosphorus in soils ways society is continuously being modernized.
have doubled in the last century because of our • However, this omnipresence of S&T must not
increased use of fertilizers. overlap the basic tenets of ethics and morality.
• We produce 23.5 million tons of phosphorus a
year. Martin Heidegger (1977): The Question
• Human activity had the biggest impact on the Concerning Technology
nitrogen cycle for 2.5 billion years. - Defined technology as (1) Instrumental and
(2) Anthropological
Global Warming
• Unusually rapid increase in Earth’s average Instrumental: Technology is a means to an end.
surface temperature over the past century Technology is not an end in itself, it is a means
primarily due to the greenhouse gases released to an end.
as people burn fossil fuels. - Aimed as to how things get done.
• Rate of temperature increase has nearly - Technology is viewed as a tool available to
doubled in the last 50 years. individuals, groups, and communities that
• Average global sea levels are higher than at desire to make an impact on society.
any point in the past 115,000 years and are
rising rapidly, which may also be detectable in Anthropological: Technology is a human
future. activity • Human activity to achieve an end and
to produce and use a means to an end is, by
6th Mass Extinction itself. • The production or invention of
• The moment of extinction is generally technological equipment, tools and machines,
considered to be the death of the last individual the products and inventions, and the purpose
of the species. and functions they serve are what define
• Mass extinctions sparked by massive global technology.
changes mark the Anthropocene period.
Technology as a way of Revealing
“There are dangers, but only dangers if people • Heidegger: true can only be pursued by the
don’t understand where technology is taking correct
us.” -Michio Kaku -What are correct leads to what is true.
-envisioned technology as a way of revealing
“bringing forth”
TECHNOLOGY AND THE FUTURE OF HUMANITY
Technological Advantages
“What defines a technological tool- one • Efficiency, Time, Communication, Jobs,
historical definition- is something that takes a Education, Transportation, Creation, Etc
The Dangers of Technology
• The sword of Damocles an analogy to
technology in a dangerous world.
• In summary, what is the story all about?
• Explain why technology in the modern world
is like the Sword of Damocles?
Sword of Damocles: “with great fortune and What is DNA, RNA, and a protein molecule?
power comes also great danger” What is DNA replication? What is the purpose
• Lies in how humans let themselves be of this process? What is transcription? What is
consumed by it. the significance of this process? What is
• Humans think nature needs to be saved, Translation? What is the significance of this
whereas mother nature would remain even if process?
humans cease to exist.
• We must not be consumed by technology lest Genomics and Proteomics
we lose the essence of who we are as humans. ▪ Genomics - deals with the DNA sequence
organization, function, and evolution of genes.
Technology in a dangerous modern world with ▪ Proteomics - aims to identify all the proteins
respect to: in a cell or organism including any
1. Terrorism posttranslational modified forms, as well as
2. Environmental remediation their cellular localization, functions and
3. Socio-technical systems interactions.
4. Imagination of disaster ▪ Genomics was made possible by the invention
5. e-learning of techniques of recombinant DNA, also known
6. e-Commerce as gene cloning or genetic engineering.
7. Human Trafficking and cybersex
8. Drug trafficking Biotechnology - The use of living organisms in
9. Social Media any form for the convenience of life.

ADVANCEMENTS IN SCIENCE AND Traditional Biotechnology


TECHNOLOGY - Used in food preservation and
production of foods
A. Cloning and GMOs - Fermentation-process where
microorganisms are used to produce a
Biological technologies could shape the society product
• Genomics & proteomics
• Biotechnology including cloning, genetic Modern Biotechnology
engineering, CRISPR - gives scientists molecular tools for
• Synthetic Biology obtaining a better understanding of the
But before you proceed, let us review the structure and function of genes in living
central dogma of biology and the genetic code organisms. (GMO, animal cloning,
table. recombinant drugs, gene therapy, plant
hybridization, biopharming, antibody
Central Dogma of Biology production, stem cell therapy)
• process by which identical copies of an
BIOTECHNOLOGY (Chapter 9- STS book- organism are made.
McNamara, SJ et al.) • The copy, or clone, possesses the same
• The Biodiversity International has released a genetic material as the original organism.
module titled “Law and Policy of relevance to • Cloning can occur naturally through asexual
the management of plant genetic resources” reproduction, wherein a single organism creates
(Bragdon et al., 2005) which aims to help a genetically identical copy of itself.
professionals in:
• Managing, Genetic Engineering
• Conserving, and • differs from cloning in keyways.
• Using plant genetic resources for food and • Whereas cloning produces genetically exact
agriculture copies of organisms, genetic engineering refers
to processes in which scientists manipulate
• Biotechnology uses biological systems, living genes to create purposefully different versions
organisms, or derivatives thereof, to make or of organisms—and, in some cases, entirely new
modify products or processes for a specific use. living things.
• Genetic engineering is a technique that allows • Geneticists have even introduced genes from
genes and DNA to be transferred from one one species to another.
source to another.
Biotechnology via gene cloning
• It leads to the production of living modified
organisms (LMOs) or genetically modified
organisms (GMOs) or obtaining a better
understanding of the structure and function of
genes in living organisms.
• Modern biotechnology gives scientists
molecular tools for obtaining a better
understanding of the structure and function of
genes in living organisms.

AIMS OF MODERN BIOTECHNOLOGY:


• Develop new precision tools and diagnostics;
• Speed up breeding gains and efficiency; GENETICALLY MODIFIED ORGANISMS (GMOs)
• Develop pest- and disease-resistant crops; ∙ Are products of artificial manipulation and
• Combat salinity, drought, and problems of alternation of a species’ genetic material in a
agriculture; laboratory using genetic engineering.
• Enhance the nutritional quality of food; ∙ Are organisms whose genetic makeup has
• Increase crop varieties and choice; been modified using recombinant DNA methods
• Reduce inputs and production costs; and (also called gene splicing), gene modification,
• Increase profits (Bragdon et al., 2005) or transgenic technology.
∙ Plant, animal, bacteria, and virus genes may be
CLONING VS GENETIC ENGINEERING combined or may be crossbred to produce
Cloning another kind of species that do not naturally
occur in the environment.
∙ Also called as transgenic organisms since the
process involves the transfer of genes. B. Medical Technologies: Targeted Medications
∙ Aims to address issues about food security,
agriculture, drug production, and nutrition. C.R.I.S.P.R. technology
∙ Herbert Boyer and Stanley Cohen - first • Means Clustered Regularly Interspaced Short
scientists to genetically modify an organism by Palindromic Repeats
combining genes from two different E. coli. • shorthand for CRISPR-CaS9
∙ Pros: • CRISPR=DNA snippets of viruses in a bacterial
✔increased crop yield DNA (new DNA becomes part of their own)
✔pest resistance • CaS 9- enzyme that acts like a pair of
∙ Cons: molecular scissors, capable of cutting strands of
✔Growing concern with how GMOs may affect DNA.
consumers’ health and the environment • Genetic engineering tool that uses a CRISPR
✔Concerns on human rights sequence of DNA and its associated protein
(Cas9) to edit the base pairs of a gene.
✔Accident in genetically engineering a virus or
• Adapted from the natural defense
bacteria may cause a serious epidemic.
mechanisms of bacteria and archaea
• Foil attacks by viruses and other foreign
∙ Humulin- first GMO approved by the Food and
bodies by chopping up and destroying the DNA
Drugs Administration (FDA), type of insulin
of a foreign invader
produced using genetically engineered E.coli
• Enable scientists to repair genetic defects
bacteria.
(genetic diseases) or use genetically modified
∙ bovine somatotropin (bST)- FDA approved
human cells as therapies.
metabolic protein hormone used to increase
milk production in dairy cows for commercial
use.
∙ Flavr Savr- FDA approved tomato for sale on
grocery stores which delays its ripening effect
and gives it a longer shelf life compared with
natural tomatoes.
∙ Bt potatoes and corn, roundup ready
soybeans
∙ Golden Rice- developed in the Philippines to
address vitamin A deficiency, which is a public
health issue in Asian countries where rice is a
staple food crop. Variety of Oryza sativa
7 Diseases that can be cured by CRISPR:
genetically modified to biosynthesize
1. Cancer
betacarotene, a precursor of Vitamin A, in the
2. Blood disorders
edible parts of rice.
3. Blindness
∙ Yorkshire pig - genetically modified to produce
4. AIDS
offspring that produce the enzyme phytase in
5. Cystic fibrosis
their saliva to digest plant phosphorus, unlike
6. Muscular dystrophy
that of normal pigs.
7. Huntington’s Disease
∙ Bt toxins in the blood of pregnant women in
eastern Quebec
Designer babies •According to US Food and Drug
• Is this kind of technology ethical? Administration,
▪ A baby genetically engineered in vitro for
specially selected traits or a baby whose genetic Types of Tests
makeup has been altered or chosen to provide There are two different types of tests –
the desired genome diagnostic tests and antibody tests.
▪ Pre-implantation genetic diagnosis- selecting 1. Diagnostic test- show if you have an active
the best egg; simplest method and used since coronavirus infection and should take steps to
1988 quarantine or isolate yourself from others.
▪ TALENS (Transcription Activator-like Effector • molecular tests, such as RT-PCR tests, that
Nucleases) detect the virus’s genetic material
▪ CRISPR • antigen tests that detect specific proteins on
the surface of the virus.
2. Antibody test- looks for antibodies that are
made by your immune system in response to a
threat, such as a specific virus. Antibodies can
help fight infections. Antibodies can take
several days or weeks to develop after you have
an infection and may stay in your blood for
several weeks or more after recovery. Because
of this, antibody tests should not be used to
diagnose an active coronavirus infection.

SYNTHETIC BIOLOGY
▪ Defined as the design and construction of new
biological parts, devices, and systems and the
re-design of existing, natural biological systems
for useful purposes.
▪ Engineer’s approach to biology

Coronavirus testing basics

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