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  • Molecular Genetics - Mutations

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    This document discusses two types of mutations in molecular genetics: point mutations, which involve a single base change and can result in silent, missense, or nonsense mutations; and frameshift mutations, which shift the reading frame by inserting or deleting bases and change all downstream coding.

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    Molecular Genetics_ Mutations

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    This document discusses two types of mutations in molecular genetics: point mutations, which involve a single base change and can result in silent, missense, or nonsense mutations; and frameshift mutations, which shift the reading frame by inserting or deleting bases and change all downstream coding.

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    © All Rights Reserved
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    6 views1 page

    Molecular Genetics - Mutations

    Uploaded by

    Nat 2.0
    This document discusses two types of mutations in molecular genetics: point mutations, which involve a single base change and can result in silent, missense, or nonsense mutations; and frameshift mutations, which shift the reading frame by inserting or deleting bases and change all downstream coding.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
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    Molecular Genetics: Mutations

    Point Mutations

    - Single base change


    - Base-pair substitution
    - Silent mutation: no change🡪 wobble
    - Missense: change amino acid
    - Nonsense: change stop codon

    Frameshift Mutations

    - Shift in the reading frame


    - Changes everything ‘downstream’
    - Insertions: adding base(s)
    - Delectrions: losing base(s)

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