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ANEMIAS
1. Anemia is a common condition. What happens when a person has anemia?

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A. The body produces too much iron
B. The blood does not have enough red blood cells

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C. The blood becomes thick
D. Too many white blood cells are produced

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2. What is the most common cause of anemia?
A. Too little sleep

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B. Too much sugar
C. Too little iron in the blood

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D. Exposure to X-ray radiation
3. Which of these groups is the most likely to have anemia?

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A. Men
B. Women

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C. Teenagers
D. Older adults

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4. How does anemia affect the body?
A. The blood doesn't deliver enough oxygen to the body

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B. Blood becomes thin
C. Tissues retain fluids uja
D. None of the above
5. A lack of which of these will result in abnormally large red blood cells and a condition called
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megaloblasticanemia?
A. Oxygen
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B. Vitamin C
C. Vitamin B-12 and folic acid
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D. Carbon dioxide
6. Which of these are signs of anemia?
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A. Pale gums
B. Dark circles under the eyes
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C. Bleeding
D. Numbness in hands and feet
7. How does iron-deficiency anemia affect teenagers?
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A. More trouble with written expression


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B. Can't concentrate
C. Aggravates hyperactivity
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D. A and B
8. Iron-deficiency anemia can cause pica, a rare condition in which a person craves eating
nonfood items. Which of these would he or she eat?
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A. Ice
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B. Soil
C. Clay
D. Any of the above
9. Anemia can contribute to which of these among older adults?
A. More falls
B. High blood pressure
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C. Diminished eyesight
D. Diabetes
10. which one of the following is example of normochromic normocytic anemia?

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a) megaloblastic anemia
b) iron deficiency anemia

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c) aplastic anemia
d) pernicious anemia

b.
11. In which type of anemia the MCV,MCH and MCHC values remain normal?

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a) hypochromic microcytic anemia
b) normochromic normocytic anemia
c) normochromic macrocytic anemia

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d) normochromic microcytic anemia

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12. low pcv value and decreased hemoglobin observed in…….
a) normochromic normocytic anemia

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b) hypochromic microcytic anemia
c) normochromic macrocytic anemia

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d) all of the above

13. in hypochromic microcytic anemia the smear impression is…….

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a) microcytosis
b) hypochromia uja
c) a and b both
d) none of the above
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14. which one of the following is example of hypochromic microcytic anemia?


a) megaloblastic anemia
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b) iron deficiency anemia


c) aplastic anemia
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d) pernicious anemia

15. in hypochromic microcytic anemia MCV, MCHC and MCH values ?


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a) normal
b) decreases
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c) increases
d) none of the above
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16. which type of anemia have elevated MCV& MCH and normal MCHC values ?
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a) normochromic macrocytic anemia


b)normochromic normocytic anemia
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c) hypochromic microcytic anemia


d) normochromic microcytic anemia
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17. smear impression of normochromic macrocytic anemia is?


a) macrocytosis
b) hyperchromia
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c) a and b both
d) none of above

18. clinical conditions observed in normochromic macrocytic anemia is?


a) pernicious anemia
b) anemia of folic acid and vit. B12 deficiency
c) aplastic anemia in some cases
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d) all of the above

19. in which condition reduction of MCH & MCV and normal MCHC is observed?

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a) normochromic microcytic anemia
b) normochromic normocytic anemia

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c) hypochromic microcytic anemia
d) normochromic macrocytic anemia
20. which would be common cause of post hemorrhagic anemia?

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a) minor wound

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b) bacterial infection
c) excess amount of blood loss
d) increase amount of platelates

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21. Content of reticulocytes in hemolytic anemia is:
a) 0-1‰

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b) 2-12‰
c) 20-25‰

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d) 40-50%

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22. Sideropenic syndrome is the result of lack of:
a) copper

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b) iron
c) vitamin B12 uja
d) folic acid

23. Sideroachrestic anemia is the result of:


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a) deficiency of copper
b) deficiency of iron
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c) disturbance utilization of iron by cells


d) deficiency of folic acid
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24. Mean corpuscular hemoglobin (МСН) in erythrocytes is:


a) 15,2-20,4 pg
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b) 25,4-34,6 pg
c) 35,5-43,2 pg
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d)45.6-56.3 pg

25. Mean corpuscular hemoglobin (MCH) in iron deficiency anemia is:


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a) 15,2-20,4 pg
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b) 25,4-34,6 pg
c) 35,5-43,2 pg
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d) 45.6-56.3 pg

26. Mean corpuscular hemoglobin (MCH) in vitamin B12 deficiency anemia is:
a) 15,2-20,4 pg
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b) 25,4-34,6 pg
c) 35,5-43,2 pg
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d) 45.6-56.3 pg

27. Destruction of erythrocytes in spleen is called:


a) erythropoiesis
b) erythrodiapedesis
c) erythrodieresis
d) erythrocentesis
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28. The term «poikilocytosis» means:
a) RBCs with a normal content of hemoglobin;
b) abnormally shaped RBCs;

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c) RBCs that are irregular in size.
d) abnormality in wbcs

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29. chronic blood loss is occus due to;
a) hookworm infestation

b.
b) prolonged excessive vaginal bleeding

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c) bleeding ulcers
d) all of the above

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30. In what anemia the color index is increased?
a) acute posthemorrhagic anemia
b) vitamin B12 deficiency anemia

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c) chronic posthemorrhagic anemia
d) sickle cell anemia

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31. In what anemia the count of reticulocytes is reduced?

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a) in the acute posthemorrhagic anemia
b) in the hemolytic anemia

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c) in the aplastic anemia
d) in chronic posthemorrhagic anemia uja
32. In what anemia the count of reticulocytes is increased?
a) acute posthemorrhagic anemia
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b) vitamin B12 deficiency anemia


c) aplastic anemia
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d) iron deficiency anemia


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33. What anemia is megaloblastic?


a) chronic posthemorrhagic anemia
b) folic acid deficiency anemia
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c) aplastic anemia
d) hemolytic anemia
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34. normal adult body contains how much amount of iron?


a)4000 mg
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b) 4000 kg
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c) 4000 pg
d) 4000 ng
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35. Syntesis of hemoglobin S is representative for:


a) thalassemia
b) sickle-cell anemia
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c) ellyptocytosis
d) pernicious anemia
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36. What enzyme deficiency in RBCs leads to ATP depletion and hemolytic anemia?
a) dehydrogenase glucose 6-phosphate
b) sodium-potassium ATPase
c) pyruvate kinase
d) hexokinase

37. which dietary factors enhance iron absorption?


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a) meat
b) fish
c) malic acid

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d) all of above

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38. which dietary factor inhibit iron absorption ?
a) coffee
b) sea food

b.
c) poultry

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d) gastric acid

39. transport and storage of iron is done by which proteins ?

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a) transferrin
b) the transferring receptors
c) ferritin

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d) all of above

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40. What kind of anemia is the result of radiation sickness?
a) aplastic anemia

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b) iron deficiency anemia
c) hemolytic anemia

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d) sickle cell anemia
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41. What kind of anemia is the result of disturbance in intrinsic Castl's factor synthesis by
gastric parietal cells?
a) hemolytic anemia
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b) iron deficiency anemia


c) vitamin В12-deficiency anemia
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d) sickle cell anemia


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42. What disturbance develops during vitamin B12 or folic acid deficiency anemia?
a) decrease of syntesis of nucleic acids
b) intensification peroxidation
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c) deranged glycolysis
d)increase synthesis of nucleic acids
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43. What factors may cause megaloblastic anemia?


a) diet deficiency in folic acid
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b) gastrectomy
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c) chronic blood loss


d) a and b both
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44. What factors may cause megaloblastic anemia?


a) intrinsic factor deficiency
b) diet exsess in folic acid
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c) chronic blood loss


d) a and b both
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45. What kind of anemia is characterized by megaloblastic type of hemapoiesis?


a) hemolytic anemia
b) chronic posthemorrhagic anemia
c) vitamin В12-deficiency anemia
d) none of the above

46. What kind of anemia is characterized by decreasing syntesis of heme?


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a) iron deficiency anemia
b) sickle-cell anemia
c) thalassemia

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d) ) hemolytic anemia

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47. in which anemia increase amount of red cell destruction is observed?
a) iron deficiency anemia
b) sickle-cell anemia

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c) thalassemia

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d) ) hemolytic anemia

48. due to corpuscular defect hemolytic anemia is classified into?

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a) intracorpuscular abnormality
b) intrinsic abnormality
c) extrinsic abnormality

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d) a and b both

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49. The causes of hemolytic anemia are
a) transfusion of mismatched blood

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b) intravenous injection of hypertonic solutions
c) malaria

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d) synthesis of hemoglobin S

50. The causes of hemolytic anemia are:


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a) severe hemorrhage
b) defective spectrin
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c) insufficiency of glucose-6-phosphate dehydrogenase in erythrocytes


d) mutation in HbS
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51. Specifications of the sickle cell anemia are:


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a) it results from abnormal hemoglobin synthesis


b) it protects against malaria
c) it is transmitted by autosome dominant trait of inheritance
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d) a and b both
52. Hemolytic anemia is not be seen until the RBCs life span is less than…….
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a) 10 days
b) 20 days
c) 30 days
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d) 40 days
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53. .what abnormal substance synthesis leads to elliptocytosis (ovalocytosis)?


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a) Hb A
b) 2,3 biphosphoglyceric acid
c) spectrin
d) HbS
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54. what abnormal substance synthesis leads to microspherocytosis?


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a) Hb A
b) 2,3 biphosphoglyceric acid
c) spectrin
d) HbS

55. The gene determining the elliptocytosis is closely linked to Rh locus on which number of
chromosome?
a) chromosome 2
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b) chromosome3
c) chromosome 1
d) chromosome 4

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56. Manifestations in patients with hemolytic anemia are:

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a) jaundice
b) increased plasma LDH
c) reticulocytosis

b.
d) all of the above

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57. What manifestations occur in patients with hemolytic anemia?
a) hemoglobinuria

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b) splenomegaly
c) increased levels of free haptoglobin
d) a and b both

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58. auto immune hemolytic anemia includes……

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a) autoantigen
b) autoantibodies

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c) haptens
d) immunogen

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59. drug induced hemolytic anemia ocuurs due to deficieny of…..
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a) hexokinase
b) glucose 6 phosphate dehydrogenase
c) pyruvate kinase
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d) aldolase

60. favism causes acute hemolytic anemia in case of……


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a) bites of snake
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b) ingestion of penicillin
c) person sensitive to fava beans
d) person sensitive to pollen seeds
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61. which one of the following is disorder is due to fundamental defect in secretion of intrinsic
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factor by the stomach?


a) hemolytic anemia
b) megaloblastic anemia
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c) pernicious anemia
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d) aplastic anemia
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