Voluntario 21

Tiempo (h) Cp Cp ln Cp lenta Residual Residual ln

0 0 0 0 0 0
0.25 0.24 -1.42711636 26.4568298 26.2168298 3.26640156
0.5 3.853 1.34885207 21.5866268 17.7336268 2.87546266
0.75 7.602 2.02841137 17.6129363 10.0109363 2.30367812
1 14.102 2.64631663 14.3707272 0.26872716 -1.31405869
1.5 12.975 2.56302443 9.56693238 -3.40806762 -
2 5.666 1.7344834 6.36893278 0.70293278 -0.35249401
2.5 3.978 1.38077918 4.23994893 0.26194893 -1.33960572
3 2.868 1.05361492 2.82263411 -0.04536589 -
4 1.102 0.09712671 1.25095736 0.14895736 -1.90409518
5 0.453 -0.79186315 0.5544092 0.1014092 -2.28859147
6 0.226 -1.48722028 0.24570746 0.01970746 -3.92675784
7 0.143 -1.94491065 Intercepto 3.48 e intercepto 32.43 mg/L
8- - Pendiente -0.81 h-1 0.81 kel

Pendiente -5.73 5.73 h-1 ka

Tmax -0.40 0.4 h
Cp max 20.13 mg/L

Tiempo (h) Cp log

0.25 -0.61978876 Chart Title
0.5 0.58579901 1.5
0.75 0.88092787
1 1.14928071
1
1.5 1.11310737
2 0.75327657
2.5 0.59966478 0.5
3 0.45757915
4 0.04218159 0
5 -0.3439018 0 1 2 3 4 5 6 7 8
6 -0.64589156
7 -0.84466396 -0.5

-1

ABC0-0.25 = 0.03 ABC0-4 = 1.985 Cpfinal = -1.86 mg/L

ABC0-0.5 = 0.511625 ABC0-5 = 0.7775
ABC0-0.75 = 1.431875 ABC0-6 = 0.3395 ABC0-∞ = 21.23 mg*h/L
ABC0-1 = 2.713 ABC0-7 = 0.1845
ABC0-1.5 = 6.76925
ABC0-2 = 4.66025
ABC0-2.5 = 2.411
ABC0-3 = 1.7115 ABC t-∞ 23.525
 Tiempo Cp simul Cp obs
0.05 6.77906116
0.1 11.6002848
0.15 14.9618223 25
0.2 17.2373882
0.25 18.7072536 0.24
0.3 19.5815242
0.35 20.0176227
0.4 20.1334187 20
0.45 20.0170891
0.5 19.734524 3.853
0.55 19.334888
0.6 18.8547965
0.65 18.3214521 15
0.7 17.7549996
0.75 17.1702947 7.602

Cp
0.8 16.5782309
0.85 15.986737
0.9 15.4015249 10

0.95 14.8266512
1 14.2649384 14.102
1.5 9.56088993 12.975
2 6.36858764
5
2.5 4.23992922 3.978
3 2.82263299 2.868
3.5 1.87909411
4 1.25095736 1.102
4.5 0.83279185
0
5 0.5544092 0.453 0 1 2
5.5 0.36908329
6 0.24570746 0.226
7 8 6.5 0.16357326
7 0.10889458 0.143
7.5 0.07249369 Simulacion sin puntos
8 0.04826076 0 Observada solo puntos
 Simulacion y Obs

0 1 2 3 4 5 6 7 8 9

Tiempo en hora

Cp obs Cp simul
mulacion sin puntos
bservada solo puntos
 Tiempo Cp simul
0 0
0.05 6.77906116
0.1 11.6002848
0.15 14.9618223 25
0.2 17.2373882
0.25 18.7072536
0.3 19.5815242
0.35 20.0176227
0.4 20.1334187
20
0.45 20.0170891
0.5 19.734524
0.55 19.334888
0.6 18.8547965
0.65 18.3214521
0.7 17.7549996 15
0.75 17.1702947
0.8 16.5782309
0.85 15.986737
0.9 15.4015249
0.95 14.8266512
10
1 14.2649384
1.5 9.56088993
2 6.36858764
2.5 4.23992922
3 2.82263299
3.5 1.87909411 5
4 1.25095736
4.5 0.83279185
8 9 5 0.5544092
5.5 0.36908329
6 0.24570746
0
6.5 0.16357326 0 5
7 0.10889458
7.5 0.07249369
8 0.04826076 Esta cinetica se suma a la ecuacion
8.05 6.78915074
8.1 11.61755
8.15 14.9840907
8.2 17.2630434
8.25 18.7350964
8.3 19.6106683
8.35 20.0474158
8.4 20.1633841
8.45 20.0468814
8.5 19.7638958
 8.55 19.363665
8.6 18.8828589
8.65 18.3487207
8.7 17.7814252
8.75 17.19585
8.8 16.602905
8.85 16.0105308
8.9 15.4244477
8.95 14.8487183
9 14.2861696
9.5 9.57511982
10 6.37806629
10.5 4.24623969
11 2.82683404
11.5 1.88189085
12 1.25281921
12.5 0.83403133
13 0.55523435
13.5 0.36963262
14 0.24607316
14.5 0.16381671
15 0.10905665
15.5 0.07260159
16 0.25807022
16.05 6.84310386
16.1 11.7098742
16.15 15.1031687
16.2 17.4002321
16.25 18.8839835
16.3 19.7665135
16.35 20.2067319
16.4 20.3236218
16.45 20.2061932
16.5 19.9209587
16.55 19.5175473
16.6 19.0329203
16.65 18.4945373
16.7 17.9227335
16.75 17.3325048
16.8 16.7348477
16.85 16.1377659
16.9 15.5470252
16.95 14.9667205
17 14.3997012
17.5 9.65121294
18 6.42875255
18.5 4.2799844
 19 2.84929878
19.5 1.89684617
20 1.26277532
20.5 0.84065935
21 0.55964678
21.5 0.37257007
22 0.2480287
22.5 0.16511856
23 0.10992332
23.5 0.07317855
24 0.04871669
 Cp simul

5 10 15 20 25

e suma a la ecuacion 32.47

32.73
25 30
Voluntario 6
Tiempo (h) Cp Cp ln Cp lenta Residual Residual ln
0 0 0 0 0 0
0.25 0.128 -2.05572502 25.9255072 25.7975072 3.25027787
0.5 2.31 0.83724752 22.4235064 20.1135064 3.00139155
0.75 5.103 1.6298286 19.3945536 14.2915536 2.65966871
1 6.878 1.92832791 16.7747498 9.89674984 2.2922064
1.5 10.434 2.3450697 12.5489844 2.11498441 0.74904744
2 9.202 2.21942085 9.38774118 0.18574118 -1.6834011
2.5 9.23 2.22245905 7.02285392 -2.20714608 Err:502
3 5.069 1.62314356 5.2537108 0.1847108 -1.68896391
4 2.274 0.8215404 2.94016171 0.66616171 -0.40622283
5 1.581 0.45805756 1.64541811 0.06441811 -2.74236046
6 1.044 0.04305949 0.92083396 -0.12316604 Err:502
7 0.336 -1.09064412 Intercepto 3.40 e intercepto 29.97 mg/L
8 0.414 -0.88188931 Pendiente -0.58 h-1 0.58 kel

Pendiente -2.78 2.78 h-1 ka

Tmax -0.71 0.71 h
Cp max 15.69 mg/L

Tiempo (h) Cp log

0.25 -0.89279003 Cp log
0.5 0.36361198 1.5
0.75 0.70782557
1 0.83746217
1
1.5 1.01845083
2 0.96388223
2.5 0.9652017 0.5
3 0.70492229
4 0.35679046 0
0 1 2 3 4 5 6 7 8 9
5 0.19893187
6 0.0187005
-0.5
7 -0.47366072
8 -0.38299966
-1

ABC0-0.25 = 0.016 ABC0-4 = 3.6715 Cpfinal = 0.31 mg/L

ABC0-0.5 = 0.30475 ABC0-5 = 1.9275
ABC0-0.75 = 0.926625 ABC0-6 = 1.3125 ABC0-∞ = 28.30 mg*h/L
ABC0-1 = 1.497625 ABC0-7 = 0.69
ABC0-1.5 = 4.328
ABC0-2 = 4.909
ABC0-2.5 = 4.608
ABC0-3 = 3.57475 ABC t-∞ 27.76625
Tiempo Cp simul Cp obs
0.05 3.0352655 Chart Title
0.1 5.58951868
0 1 2 3 4 5
0.15 7.72771158 12
0.2 9.50628995
0.25 10.9743 0.128 10

0.3 12.1743515 8
0.35 13.1434552
6
0.4 13.9137522
0.45 14.5131481 4
0.5 14.9658646 2.31
2
0.55 15.2929199
0.6 15.5125462 0
0 1 2 3 4 5
0.65 15.6405533
0.7 15.6906445 Cp obs
0.75 15.674692 5.103
0.8 15.602976
0.85 15.4843927
0.9 15.3266359
0.95 15.1363542
1 14.9192879 6.878
1.5 12.0873453 10.434
2 9.27288534
2.5 6.99427778 9.23
3 5.24660105 5.069
3.5 3.92846765
4 2.93972161 2.274
4.5 2.19938938
5 1.64539087 1.581
5.5 1.23091031
6 0.92083228 1.044
6.5 0.68886416
7 0.51533103 0.336
7.5 0.38551287
8 0.28839746 0.414
 Chart Title
2 3 4 5 6 7 8 9
18
16
14
12
10
8
6
4
2
0
2 3 4 5 6 7 8 9

Cp obs Cp simul
Tiempo Cp simul
0 0
0.05 3.0352655 Cp simul
0.1 5.58951868 18
0.15 7.72771158 16
0.2 9.50628995
14
0.25 10.9743
12
0.3 12.1743515
0.35 13.1434552 10
0.4 13.9137522 8
0.45 14.5131481 6
0.5 14.9658646
4
0.55 15.2929199
2
0.6 15.5125462
0.65 15.6405533 0
0 5 10 15
0.7 15.6906445
0.75 15.674692
0.8 15.602976
0.85 15.4843927
0.9 15.3266359
0.95 15.1363542
1 14.9192879
1.5 12.0873453
2 9.27288534
2.5 6.99427778
3 5.24660105
3.5 3.92846765
4 2.93972161
4.5 2.19938938
5 1.64539087
5.5 1.23091031
6 0.92083228
6.5 0.68886416
7 0.51533103
7.5 0.38551287
8 0.28839746 Esta cinetica se suma a la ecuacion
8.05 3.06446915
8.1 5.64329795
8.15 7.80206335
8.2 9.59775422
8.25 11.0798887
8.3 12.2914864
8.35 13.2699143
8.4 14.0476227
8.45 14.6527856
8.5 15.1098579
 8.55 15.4400599
8.6 15.6617994
8.65 15.7910381
8.7 15.8416113
8.75 15.8255053
8.8 15.7530992
8.85 15.633375
8.9 15.4741004
8.95 15.2819878
9 15.0628331
9.5 12.2036431
10 9.36210392
10.5 7.06157286
11 5.29708095
11.5 3.96626519
12 2.96800599
12.5 2.22055069
13 1.66122191
13.5 1.24275345
14 0.92969202
14.5 0.69549203
15 0.52028926
15.5 0.38922206
16 0.25807022
16.05 3.09060181
16.1 5.6914219
16.15 7.86859646
16.2 9.67960031
16.25 11.1743739
16.3 12.3963036
16.35 13.3830752
16.4 14.1674156
16.45 14.7777391
16.5 15.2387092
16.55 15.571727
16.6 15.7953574
16.65 15.9256982
16.7 15.9767026
16.75 15.9604593
16.8 15.8874358
16.85 15.7666906
16.9 15.6060578
16.95 15.412307
17 15.1912834
17.5 12.3077112
18 9.44194047
18.5 7.12179134
 19 5.3422525
19.5 4.00008803
20 2.99331604
20.5 2.23948673
21 1.6753882
21.5 1.25335119
22 0.93762008
22.5 0.70142293
23 0.5247261
23.5 0.3925412
24 0.29365527
 Cp simul

5 10 15 20 25 30

e suma a la ecuacion 30.26

30.52
Voluntario 3
Tiempo (h) Cp Cp ln Cp lenta Residual Residual ln
0 0 0 0 0 0
0.25 0.251 -1.38230234 26.7176737 26.4666737 3.27588635
0.5 2.017 0.70161126 23.0977976 21.0807976 3.04836256
0.75 3.777 1.32893004 19.9683647 16.1913647 2.78447806
1 3.781 1.32998852 17.2629268 13.4819268 2.60135004
1.5 4.335 1.46672161 12.9020372 8.56703717 2.14792195
2 3.592 1.27870915 9.64277754 6.05077754 1.80018678
2.5 7.972 2.0759354 7.20685869 -0.76514131 -
3 5.65 1.73165555 5.38629165 -0.26370835 -
4 3.189 1.15970739 3.00869097 -0.18030903 -
5 1.355 0.30380145 1.68060364 0.32560364 -
6 0.708 -0.34531119 0.93875663 0.23075663 -
7 0.63 -0.46203546 Intercepto 3.4309133 e intercepto 30.90 mg/L
8 0.326 -1.1208579 Pendiente -0.58 h-1 0.58 kel

Pendiente -0.85 0.85 h-1 ka

Tmax -1.41 1.41 h
Cp max 4.25 mg/L

Tiempo h Cp log
0.25 -0.60032628
0.5 0.3047059 Chart Title
0.75 0.57714698 1
1 0.57760668
0.8
1.5 0.6369891
2 0.55533633 0.6
2.5 0.90156729 0.4
3 0.75204845 0.2
4 0.50365452
0
5 0.1319393 0 1 2 3 4 5 6 7 8 9
6 -0.14996674 -0.2
7 -0.20065945 -0.4
8 -0.4867824
-0.6

-0.8

ABC0-0.25 = 0.031375 ABC0-4 = 4.4195 Cpfinal = 0.30 mg/L

ABC0-0.5 = 0.2835 ABC0-5 = 2.272
ABC0-0.75 = 0.72425 ABC0-6 = 1.0315 ABC0-∞ = 21.68 mg*h/L
ABC0-1 = 0.94475 ABC0-7 = 0.669
ABC0-1.5 = 2.029 ABC0-8 = 0.478
ABC0-2 = 1.98175
ABC0-2.5 = 2.891
ABC0-3 = 3.4055 ABC t-∞ 21.161125
Tiempo Cp simul Cp obs
0.05 0.3968184
0.1 0.76576605
0.15 1.10832744 9
0.2 1.42591601
0.25 1.71987741 0.251
0.3 1.99149252 8
0.35 2.24198043
0.4 2.47250124
0.45 2.68415877
0.5 2.87800309 2.017 7

0.55 3.05503302
0.6 3.21619846
0.65 3.36240264 6
0.7 3.49450424
0.75 3.61331949 3.777
0.8 3.71962409
5
0.85 3.81415511
0.9 3.89761274
0.95 3.97066205
1 4.03393458 3.781 4
1.5 4.24684356 4.335
2 3.98003506 3.592
2.5 3.50195573 7.972 3
3 2.96232376 1.08597401
3.5 2.4397248
4 1.97109826 0.67859088
2
4.5 1.56979295
5 1.23645641 1.355
5.5 0.96546891
6 0.74863698 0.708 1
6.5 0.5772242
7 0.44299174 0.63
7.5 0.33866363 0
0 1
8 0.25807022 0.326
 Chart Title

1 2 3 4 5 6 7

Cp obs Cp simul
 Tiempo Cp simul
0 0
0.05 0.3968184
0.1 0.76576605
4.5 0.15 1.10832744
0.2 1.42591601
0.25 1.71987741
4
0.3 1.99149252
0.35 2.24198043
0.4 2.47250124
0.45 2.68415877
3.5 0.5 2.87800309
0.55 3.05503302
0.6 3.21619846
3 0.65 3.36240264
0.7 3.49450424
0.75 3.61331949
0.8 3.71962409
2.5
0.85 3.81415511
0.9 3.89761274
0.95 3.97066205
2 1 4.03393458
1.5 4.24684356
2 3.98003506
1.5 2.5 3.50195573
3 2.96232376
3.5 2.4397248
4 1.97109826
1
4.5 1.56979295
5 1.23645641
5.5 0.96546891
0.5 6 0.74863698
6.5 0.5772242
7 0.44299174
0 7.5 0.33866363
6 7 8 9
8 0.25807022 Esta cinetica se suma a la ecuacion
8.05 0.40013203
8.1 0.77216056
8.15 1.1175825
8.2 1.43782309
8.25 1.7342392
8.3 2.00812243
8.35 2.26070203
8.4 2.4931478
8.45 2.70657277
8.5 2.90203578
 8.55 3.080544
8.6 3.24305525
8.65 3.39048029
8.7 3.52368501
8.75 3.64349242
8.8 3.75068472
8.85 3.84600511
8.9 3.93015965
8.95 4.00381896
9 4.06761985
9.5 4.28230672
10 4.01327024
10.5 3.53119872
11 2.98706057
11.5 2.46009766
12 1.98755787
12.5 1.58290146
13 1.24678141
13.5 0.97353104
14 0.75488845
14.5 0.5820443
15 0.44669093
15.5 0.34149164
16 0.25807022
16.05 0.40344565
16.1 0.77855507
16.15 1.12683756
16.2 1.44973016
16.25 1.748601
16.3 2.02475234
16.35 2.27942363
16.4 2.51379436
16.45 2.72898677
16.5 2.92606848
16.55 3.10605498
16.6 3.26991203
16.65 3.41855795
16.7 3.55286578
16.75 3.67366535
16.8 3.78174535
16.85 3.87785512
16.9 3.96270657
16.95 4.03697587
17 4.10130512
17.5 4.31776988
18 4.04650542
18.5 3.56044171
 19 3.01179738
19.5 2.48047053
20 2.00401747
20.5 1.59600998
21 1.2571064
21.5 0.98159316
22 0.76113993
22.5 0.58686439
23 0.45039013
23.5 0.34431964
24 0.26238024
 Simulacion de
5

4.5

3.5

2.5
Cp

1.5

0.5

0
0 5 10 15

Tiempo a 3 d

e suma a la ecuacion 31.16

31.42
Simulacion de 3 dosis

10 15 20 25 30

Tiempo a 3 dosis