Drug Study: Montelukast

Generic Name: Montelukast Trade/Brand Name: Singulair

Contents: Montelukast is available in tablet and chewable tablet forms, with

dosages ranging from 4mg to 10mg.

Patient’s Dose: The dosage and frequency of administration will depend on the
individual's age, weight, and medical condition. Montelukast is usually taken once
daily, either in the morning or evening, with or without food.

Minimum Dose: 4mg once daily for children aged 6 to 14 years old.

Maximum Dose: 10mg once daily for adults and children aged 15 years old and
above.

Classification: Montelukast is a leukotriene receptor antagonist.

Mechanism of Action: Montelukast blocks the action of leukotrienes, which are

substances in the body that cause inflammation and narrowing of the airways in
response to asthma triggers. By blocking leukotrienes, montelukast reduces
inflammation and relaxes the airways, making it easier to breathe.

Indications: Montelukast is indicated for the treatment of asthma, including

prevention of symptoms and prevention of exercise-induced bronchoconstriction. It
is also indicated for the treatment of allergic rhinitis, including seasonal allergies.

Contraindications: Montelukast should not be used in patients with a known

hypersensitivity to any component of the product. It is also contraindicated for the

treatment of acute asthma attacks.

Side Effects: Common side effects of Montelukast include headache, stomach pain,
diarrhea, and nausea. Less common side effects may include dizziness, sleep
disturbances, and rash. Rarely, Montelukast can cause serious side effects,
including allergic reactions, changes in behavior or mood, and liver problems. If the
patient experiences any severe symptoms, they should seek medical attention
immediately.
Nursing Responsibilities:

Before administration: The nurse should assess the patient's medical history and
allergies. They should also educate the patient and family members on the proper
administration and potential side effects of the medication.

During administration: The nurse should monitor the patient for adverse
reactions, including changes in behavior or mood, and report any concerns to the
healthcare provider.

After administration: The nurse should document the administration of the

medication and any observed side effects in the patient's medical record. They
should also follow up with the patient to assess their response to the medication
and provide further education and support as needed.

References:

Singulair Prescribing Information. Merck Sharp & Dohme Corp. Updated May 2021.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/020829s071,021108s
032lbl.pdf

Montelukast. Lexicomp Online. Wolters Kluwer Clinical Drug Information, Inc.

Accessed April 3, 2023.
https://online.lexi.com/lco/action/doc/retrieve/docid/patch_f/7300199#f_adverse-
reactions

Simon F, Ward C. Montelukast. StatPearls Publishing. Updated December 2021.

https://www.ncbi.nlm.nih.gov/books/NBK555979/