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Route, frequency, and dosage

Nursing Consideration Monitor for hyperurecemia, especially in patient with leukemia lymphoma and monitor for toxicity Check for depression of achilles tendons reflex, numbness, tingling, foot drop/ wrist drop, difficulty in walking, ataxia, and slapping gait Watch for constipation Always check the medication and asses that this medication is for IV only Asses the IV site before and after administeri ng the drug Explain the client the purpose and the possible side effect of the drug

evaluation The client doesnt develop Any adverse effect of the drug like hyper urecemia Rehydration for the client is maintained and theres no signs of constipation of the client and the nausea and vomiting of the client is tolerable Goal met

Antineoplastic Mitotic Inhibitor

Mitotic Inhibitor Arrest of Mitotic division at the stage of metaphase Interfering the genetic material in the cell multiplies IV Not to exceed 2 mg/dose

Generic name: Vincristine Sulfate

Brand Name: Oncovin Vincasar PFS




Route, frequency, and dosage

Nursing Consideration Check if patient have allergy to mercaptopurine, prior resistance to mercatopurine Check if patient have any renal disease Ensure that patient is well hydrated before and during the therapy to minimize the\e adverse effect of hyperuricemia Teach the client parent that he may experience nausea and vomiting after the treatment Monitor if patient will be having fever, chills, sore throat, unusual bleeding, yellow discoloration of the eyes or skin, abdominal pain, frank palm, joints pain, weakness and diarrhea

evaluation The patient have no allergies to mercaputorine Nausea and vomiting of the client is tolerable and theres no sign of dehydration Theres minimal adverse effect that happen to the client

Generic Antimetabolite Name: Mercaplopurin Antineoplastic

Tumorinhibiting proteins Interference with prine nucleotide sythesis RNA and DNA synthesis /dose PO qd

Brand Name: Purinethol

Lead to cell death ; cellcycle specific




Route, frequency, and dosage

Nursing Consideration Asses allergy to methotrexate Monitor pulmonary function test periodically as ordered Encourage fluid intake Monitor for any rashes, redness/ulceration in the mouth Instruct the significant others to use highly protective sun block Teach the significant other that patient may experience adverse effects of the medicines such as nausea and vomiting, drowsiness, mouth sore, blurred vission

evaluation The patient have no known allergies to methotrexate The patient tolerate nausea and vomiting and theres no signs of dehydration The patient dont develop any rashes, redness/ ulceration in the mouth The client verbalize understanding about the procedure

Antimetabolite Generic Name: Methotrexate Antineoplastic Antipsoriatic Antirheumatic Brand Name: Rheumatrex Trexall

Inhibits folic acid reductase

Leading to inhibitor of DNA synthesis and inhibitor of cellular replication Selective affects the most rapidly dividing cells

PO/IV/IM 2-6 qwk to every month