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Strong Opioid Agonists Are
Strong Opioid Agonists Are
The two most commonly used centrally acting opioid receptor antagonists are naloxone and
naltrexone. Naloxone comes in intravenous, intramuscular, and intranasal formulations and is
FDA-approved for the use in an opioid overdose and the reversal of respiratory depression
associated with opioid use.