Bacteria viruses or fungi enter the bone structure

and cause infection

Create an inflammatory response that causes

leaky blood vessels and edema in surrounding
tissues.

Eukocytes (a form of white blood cells) rush to the

affected area and secret enzymes in an attempt to
kill the foreign bacteria.

Pus is formed and causes increased pressure

within the bone pus is formed and causes
increased pressure within the bone
structuresstructures

Leads to rupture within bone structures and may

occlude blood supply, leading to ischemia and
bone death

This necrotic encapsulation is called sequestrum

(infected dead bone resulting from osteomyelitis).

Chronic osteromyelitis