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Alzheimer's disease

Research Proposal · January 2021

DOI: 10.13140/RG.2.2.33163.52003

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Eman Abdulghany
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 Alzheimer’s disease
Eman Anwer Abdulghany
E-mail: eman.2318101@stemkalubya.moe.edu.eg

Abstract: Alzheimer's is a type of decade, degenerative diseases of the brain

were considered to be among the most
dementia that affects thinking, memory and
mysterious and intractable disorders in
behavior. Symptoms ultimately grow
medicine. Alzheimer's disease epitomized
enough to intervene with daily tasks.
the curative nihilism and the mechanistic
Studies of the molecular basis of
ignorance that pervaded the study of
Alzheimer's disease exemplify the
neurodegeneration in humans. But research
increasingly blurred distinction between
advances in two broad areas—molecular
basic and applied biomedical research. The
genetics and biochemical pathology — have
four genes so far involved in familial
combined to offer new hope and to
Alzheimer's disease have each been shown
stimulate research. Determining the
to raise brain levels of the self-aggregating
composition of the classical brain harm and
amyloid-β protein, leading progressively to
identifying at least four genes that
deep neuronal and glial change, synaptic
predispose individuals to the disorder have
loss and dementia. Progress in
increased the understanding of the
understanding this cascade has helped to
genotype-to-phenotype relationships that
distinguish specific curative targets and
underlie inherited forms of Alzheimer’s
provides a model for clarify other
disease.
neurodegenerative disorders.

Index terms: Alzheimer- disorder-

causes- treatment
I. Introduction:
The most common cause of dementia is
Alzheimer’s. The most known cause for
Alzheimer is increasing age but senility is
not always the reason behind Alzheimer.
The most common early symptom of
Alzheimer’s is difficulty in remembering
newly learned information. Until the last
II. IDENTIFY, RESEARCH
AND COLLECT IDEA:
Alzheimer is the most common type of
dementia. Alzheimer can lead to the
dying of neurons in many areas of the
brain like hippocampus and cerebral
cortex. Alzheimer can start by being not
able to remember the new information
and then losing the ability to carry a
conversation and to respond to the
environment. Scientists do not fully
understand the causes of this disease.
There probably is not one single cause,
but several factors that affect each
person differently.
- Age is the most known cause to
Alzheimer.
- Family history. researchers believe
that genetics play an important role
in developing this disease.
- Scientists are finding more evidence
that some of the risk factors for
heart disease and stroke, such as
high blood pressure and high
cholesterol may also increase the
risk of Alzheimer’s disease
- There is evidence that mental,
physical and social activities can
reduce the risk of Alzheimer’s
disease.
it also thought to be caused by the
abnormal
build-up of
proteins in and
around brain
cells. One of
the proteins
involved is
called amyloid,
deposits of
which form Figure 1
plaques around brain cells.
The other protein is called tau, deposits
of which form tangles within brain cells.
(fig.1)
There is no cure for Alzheimer but there
are some ways to reduce the risk of
these disease:
- Social engagement
- Quality sleep
- Stress management
- Regular exercise
- Healthy diet
- Mental stimulation
- Vascular health
Alzheimer’s disease research has
developed that scientists can look
beyond treating symptoms to think
about addressing underlying disease
processes.
III. STUDIES AND FINDINGS:
In this research paper it has been known
how Alzheimer’s disease is an
irreversible, progressive brain disorder
that slowly destroys memory and
thinking skills and, eventually, the ability
to carry out the simplest tasks.
- aging is not only the cause of
Alzheimer there are some other causes
and one of them is genetic cause. And it
thought that the disorder of proteins
can be the cause of the disease.
- Researchers did not have a cure
to it but its symptoms can be
reduced by a lot of activities and
social engagement.
 Conclusion:
Alzheimer’s disease is a mental
deterioration, or dementia,
characterized by confusion and memory
loss. It can lead to death. Researchers
believe that there are various causes for
Alzheimer like proteins disorder, family
history or aging. There is no cure for this
disease but there are some ways to
reduce the symptom of it.
Citation:
- What is Alzheimer's Disease? (2020,
June 02). Retrieved from
https://www.cdc.gov/aging/aginginf
o/alzheimers.htm
View publication stats
- What Is Alzheimer's Disease? (n.d.).
Retrieved from
https://www.nia.nih.gov/health/wh
at-alzheimers-disease
- 7 Ways To Reduce The Risk Of
Alzheimer's Disease. (2015, October
19). Retrieved from
https://www.cambridgecognition.co
m/blog/entry/7-ways-to-reduce-the-
risk-of-alzheimers-disease
- Alzheimer's disease. (2018,
December 08). Retrieved from
https://www.mayoclinic.org/disease
s-conditions/alzheimers-
disease/symptoms-causes/syc-
20350447