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MULTIPLE CHOICE
REF: p. 99
REF: p. 104
REF: p. 105
4. Which of the following occurs during acute illness or trauma?
a. Negative acute-phase respondents increase.
b. Positive acute-phase respondents decrease.
c. Negative acute-phase respondents decrease.
d. Both positive and negative acute-phase respondents increase.
ANS: C
Negative acute-phase proteins are those that are negatively affected by trauma, meaning that
their levels and production decrease in response to the trauma. These include albumin,
transferrin, prealbumin, and retinol-binding protein. Positive acute-phase respondents are
those that increase in levels and production in response to trauma.
REF: p. 103
REF: p. 103
REF: p. 103
REF: p. 104
REF: p. 108
10. Which of the following manifestations will occur in iron deficiency anemia?
a. Microcytic anemia
b. Macrocytic anemia
c. High reticulocyte count
d. High MCV
ANS: A
Microcytic anemia is mostly associated with iron deficiency. Macrocytic anemia, which
would be reflected by a high MCV value, is usually caused by either folate or vitamin B12
deficiency. Reticulocytes are large, nucleated, immature red blood cells that are released in
small numbers with mature red blood cells. The presence of these may indicate erythropoiesis
in response to blood loss, hemolysis, or iron, folate, or vitamin B12 therapies.
REF: p. 105
REF: p. 105
REF: p. 105
REF: p. 109
15. Which laboratory value would be added in a comprehensive metabolic panel (compared with
a BMP)?
a. Albumin
b. Glucose
c. Blood urea nitrogen
d. White blood cells
ANS: A
The Centers for Medicare and Medicaid Services established that for the BMP, the following
tests are reimbursable: glucose, calcium, potassium, carbon dioxide, chloride, blood urea
nitrogen, and creatinine. For the CMP, the following are added: albumin, total protein,
alkaline phosphate, alanine aminotransferase, aspartate aminotransferase, and bilirubin. WBC
would appear on a CBC, which may include a differential identifying the levels of the
different types.
REF: p. 103
The percentage of glycosolated hemoglobin (hemoglobin A1C) in the blood is directly related
to the average blood glucose levels for the preceding 2 to 3 months. Homocysteine and
hs-CRP are two inflammatory markers, higher levels of which are associated with increased
risk of cardiovascular disease. Apolipoprotein B is the part of the protein present in
low-density lipoprotein, and it is also associated with increased risk of atherogenesis, possibly
through its susceptibility to oxidation by ROS and lipid peroxides.
REF: p. 109
18. BMIs of _______ are associated with increased risk of mortality in those 65 and older.
a. less than 23
b. less than 18.5
c. greater than 24.9
d. there is no association between BMI and risk of mortality
ANS: A
Differences in race, sex, and age must be considered when evaluating the BMI. BMI values
tend to increase with age, yet the relationship between BMI and mortality appears to be
U-shaped in adults aged 65 and older. The risk of mortality increased in older adults with a
BMI of less than 23.
REF: p. 113
19. In urinalysis tests, which of the following is expected to appear at some level in normal
people?
a. Glucose
b. Ketones
c. Blood
d. Protein
ANS: D
Small amounts of protein, from 2 to 8 mg/dL, are expected in normal urine. Larger amounts
are associated with damage to the kidneys. Results for glucose, ketones, and blood in the urine
are expected to be negative.
REF: p. 102