2nd MBBS - Jan 2022 (RS4 – CBME) Batch

Pathology Revision Test -38

Pre-final-1

Answer all the questions. Date: 14/01/202

Draw the diagram wherever necessary. Duration: 3 Hrs.
Q No. 21 to 30 will have MCQs Total Marks: 100

Long Essays: 2X10=20

1) A 65-year-old female presented with bleeding per vagina. Per speculum examination showed an
ulceroproliferative lesion involving the external os which bleeds on touch.
Answer the following
a) What is the clinical diagnosis?
b) Describe the etiopathogenesis and morphology of these lesions.
c) Screening methods of this condition.
2) Classify breast tumours. Mention the risk factors and pathogenesis of breast cancer. Describe the
gross and microscopic features of Infiltrating duct carcinoma.

Short Essays: 8X5=40

3) Type II hypersensitivity reaction.
4) Blood and bone marrow picture in multiple myeloma.
5) Sideroblastic anaemia.
6) Down’s syndrome.
7) Burkitts lymphoma.
8) Transfusion reactions.
9) Mechanism of apoptosis.
10) Von Wwillebrand disease.

Short Answers: 10X3=30

11) Sago spleen.
12) Antioxidants.
13) Causes of microcytic hypochromic anaemia.
14) RBC inclusions.
15) Precancerous lesions.
16) Tests for haemoglobinuria in urine and conditions, principle of Benzidine test.
17) Causes for eosinophilia.
18) Gamna Gandy bodies.
19) Ochronosis.
20) Wintrobe’s tube.

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Multiple Choice Questions: 10X1=10
21) The peripheral blood smear of a silent carrier of α thalassemia typically appears as :
a) Normocytic , normochromic
b) Macrocytic, normochromic
c) Microcytic , hypochromic
d) Macrocytic , hpochromic
22) Laboratory findings in aplastic anemia include all of the following except :
a) Low reticulocyte count
b) Normocellular bone marrow
c) High ESR
d) Low neutrophil count
23) Leukemoid reaction is characterized by the following except :
a) Leucocytosis
b) Increased band forms
c) Shift to the right
d) Increased NAP score
24) A 42-year old man was referred with a 2 week history of fever weakness and bleeding gum.
Peripheral smear showed pancytopenia. The bone marrow examination revealed 26% blasts
frequency exhibiting Auer rods and mature myeloid cells. An occasional neutrophil with
pseudo Pelger-Huet anomaly was also detected. Which of the following cytochemical stains is
most likely to be positive?
a) Acid phosphatase
b) Non-specific esterase
c) Myeloperoxidase
d) Toluidine blue
25) The classification proposed by the International Lymphoma Study Group for non-Hodgkin
lymphoma is
a) Kiel classification
b) REAL classification
c) WHO classification
d) Rappaport classification
26) The most common secondary malignancy in a patient having retinoblastoma is:
a) Osteosarcoma
b) Renal cell carcinoma
c) Pineoblastoma
d) Osteoblastoma
27) Tumors associated with organisms are all except:
a) Hepatocellular cancer
b) Non-small Cell Carcinoma of Lung
c) Gastric cancer
d) Nasopharyngeal cancer
28) Activated partial thromboplastin time is prolonged in :
a) Hemophilia B
b) Factor VIII deficiency
c) Blood vessel disease
d) Hemophilia B & factor VIII deficiency
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 29) The most definitive diagnostic test for HCV infection is :
a) HCV Ab IgG by ELIZA
b) HCV Ab IgM by ELIZA
c) Recombinant immunoblot assay (RIBA)
d) Viral RNA by PCR
30) Anti-n-DNA antibodies in SLE are :
a) Associated with kidney affection
b) Used in diagnosis and follow up
c) Detected by IIF technique
d) All of the above

."Failure will never overtake me if my definition to succeed is strong enough." – Dr. APJ Abdul Kalam
ALL THE BEST J

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