Oncology Our scientists take a rigorous, comprehensive approach to understanding cancer biology and drug discovery. Challenge ‘We have made great strides in our understanding of cancer, but more needs 10 be done, Historically cancer was treated asa single dlseaso, but wo now know that there are more than 200 diferent types, each with different behavious, rates of growth and stages of progression. Several ‘cancer types and subtypes remain stubbornly difficult to treat and major inequalities stil exist terms ‘of outcomes. This, tled with our growing and ageing population, anc new and emerging factors (diet, ‘emironmert, exposure, etc), constitute an ever-increasing burden on society, (Our ultimate vision isto prevent and provide cures for cancer in alits forms. As no single interventions Leo to achieve this, we sack to comprehonsively understand the disease, is complexities and ts impact ‘on pationts, By giving our researchers the freedom to explore the cutting edge of science and technology we deepen our understanding ofthe biology and immunology of cancer to make this sion @ reality sooner,Focus For more than 60 years, we have developed innovative medicines and diagnostics that help prevent, detect, diagnose, treat and monitor cancer We strive to transform the ves of people wth cancer, as well as those who support them, Our focus thus les in pushing for progress in cancer prevention, increasing disease awareness, develoging innovative screering and diagnostic technologies, and ‘advancing our understanding ofthe disease andits causes, With our leasing Pharmaceuticals and Diagnostics businesses under one oof, and a strong R&D pipalne, we are better positioned to deliver personalized healthcare than ary other company. Cases in detail ES” AEG S\N Cancer immunotherapy > For more than 80 years, Roche has been develozing medicines with the goal ‘to redefine treatment n oncology. Today, wee investing more than ever to bring personalised immunotherapy to people with cancer Breast cancer 2 Breast cancer isa hugely complex disease. Our research and solutions aim to {further our understanding of breast cancer and improve outcomes for ‘everyone affected by this dlsease Liver cancer 2 aa Lung cancer > Lung cancer isa complex disease, but ongoing research, advances clinical trials and inestigatonal medicines in the pineline wil continue to uncover ‘answers that save and improve lve. Haematology > Haematology isa complex and challenging area of medicine. At Roche, ‘inging innovative solutions for those affected by diseases of the bloods a rarity Skin cancer >HCCis known asasilent kil’ asthe symptoms often appear toolate for We have been studying stn cancer for over 20 years, continuously expanding ‘curative treatments, Learn more about the signs, symptoms and risk factors. our understanaing of the disease inorder to bring the best solutions to patients affected by skin cancer Cervical cancer 2 [At Roche, women's health sa priority and that starts with cervical cancer Other case examples fae Bo Understanding the impact of bladder cancer Colorectal cancer November 03,2027 November 03,2021 Diagnostics in oncology Every cancer s unique. Throughout each person's journey, diagnostic testing helps to uncover key insights that support better outcomes, Read moreStories of Oncology Fromidea, to molecule, to me May 23,2028 © Video Margareth Lasut, Indonesia February 02,2025, Seemore stories —> Tailoring the way patients receive treatment May 17,2028More focus areas B+ Cardiometabolic diseases Discover more > Viewallfocus areas > Diabetes > Haematology > Innovation Partnering > [At Rache Partnering, we are passionate about science: yours and ours, Through partnerships, we hope that together we can buld a better future vith medicines that make a rel difference to patients, Innovation Clinical trials > Cincal trials are essortial to determine whether new drugs or ciagnostics are safe and effective when used to diagnose or treat people, About Roche The frontrunner in personalised healthcare > Shifting away from a one-size-is all approach to delivering the best care for ‘each person.