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Cyclic Load Testing and Ultimate Failure Strength of Suture

Anchors in the Acetabular Rim

Michell Ruiz-Suarez, M.D., M.S., Jorge Aziz-Jacobo, M.D., and F. Alan Barber, M.D.

Purpose: To determine the resistance to cyclic stress and load-to-failure strength of several suture
anchors suitable for hip arthroscopy. Methods: Ten polyetheretherketone (PEEK) PushLock, PEEK
SutureTak, and Bio-SutureTak anchors (Arthrex, Naples, FL); Lupine Loop BR anchors (DePuy
Mitek, Norwood, MA); Bio-Mini Revo anchors (ConMed Linvatec, Largo, FL); and BioRaptor 2.9
AB anchors (Smith & Nephew, Andover, MA) were inserted in rotation into different locations on
the rim of 4 matched pairs of potted acetabula clamped to the base of a servohydraulic testing
machine. The anchors’ sutures were cyclically pulled in line with the insertion angle. Displacement
at 100 and 500 cycles, yield load, ultimate failure load, and failure mode were recorded. Statistical
analysis was performed. Results: Most of the displacement observed during cyclic loading occurred
in the first 100 cycles, except for the BioRaptor 2.9 AB, which showed twice as much displacement
at 500 cycles as at 100 cycles. The Lupine Loop BR cyclic displacement was greater than that of the
PEEK PushLock (at 100 cycles also), Bio-SutureTak, and PEEK SutureTak at 500 cycles (P ⬍ .05).
The BioRaptor 2.9 AB cyclic displacement was significantly greater at 100 and 500 cycles than that
of the PEEK PushLock and Bio-SutureTak (P ⬍ .05). The mean ultimate failure loads for these
anchors ranged from 154 N (PEEK SutureTak) to 255 N (Bio-Mini Revo) and was statistically
equivalent (P ⫽ .139). Correlation analysis showed no significant associations between anchor
stiffness, cyclic load displacement, or failure load. Conclusions: Anchors with specific indications
for hip arthroscopy showed very little displacement and had consistent failure loads under cyclic
conditions in the acetabular rim. All hip anchors except the BioRaptor 2.9 AB showed less than 2.0
mm of displacement after 500 cycles. Clinical Relevance: Biomechanical testing of suture anchors
designated for hip arthroscopy should be performed in the acetabular rim before their use. Suture
anchors used for shoulder arthroscopy may not perform as well in the hip.

S uture anchors are commonly used for shoulder


capsulolabral repairs1-4 and offer advantages over
older suture fixation techniques.5 Many of the same
much the same way as shoulder glenoid surgery.
Whereas single-pull load-to-failure strength testing
provides one element of an anchor’s properties, the
arthroscopic techniques developed for use in the gle- anchors used in these labral repairs are actually sub-
nohumeral joint are now being applied to the hip. Hip jected to multiple submaximal cyclic loads. In the
labral tears can be repaired with suture anchors in glenoid labral repair, a displacement of 5 mm after
cyclic loading would constitute a clinical failure.6,7
Currently, there are no data available for hip labral
From the Instituto Nacional de Rehabilitación (M.R.-S.), Mexico repairs to suggest how much displacement would con-
City, Mexico; and Plano Orthopedic Sports Medicine and Spine stitute a clinical failure.
Center (J.A.-J., F.A.B.), Plano, Texas, U.S.A. Although many similarities exist, the acetabular rim
Supported by Arthrex, Smith & Nephew Endoscopy, ConMed Lin-
vatec, and DePuy Mitek. Research was performed at Arthrex, Naples, is different from the glenoid. Anchors placed in the
FL. acetabular rim may show different failure profiles than
Received April 12, 2009; accepted October 22, 2009.
Address correspondence and reprint requests to F. Alan Barber,
anchors placed in the glenoid rim. The number of
M.D., Plano Orthopedic Sports Medicine and Spine Center, 5228 W suture anchors approved by the Food and Drug Ad-
Plano Pkwy, Plano, TX 75093, U.S.A. ministration for use in the acetabulum is limited. Test-
© 2010 by the Arthroscopy Association of North America
0749-8063/9206/$36.00 ing of these anchors in the acetabulum with submaxi-
doi:10.1016/j.arthro.2009.10.013 mal cyclic loads should provide a test environment

762 Arthroscopy: The Journal of Arthroscopic and Related Surgery, Vol 26, No 6 (June), 2010: pp 762-768
SUTURE ANCHORS IN ACETABULAR RIM 763

more consistent with the in vivo situation. The pur-


pose of this study was to determine the resistance to
cyclic stress and load-to-failure strength of several
suture anchors suitable for hip arthroscopy. The hy-
pothesis was that new suture anchors indicated for hip
arthroscopy would show different biomechanical
characteristics in the acetabulum than anchors not
designed for that location.

METHODS
Four matched pairs of fresh-frozen acetabula (all
male specimens; age range, 53 to 65 years) were FIGURE 2. The PEEK hip PushLock anchor is a radiolucent, non-
absorbable PEEK 5.5-mm anchor with a closed 2-mm distal PEEK
thawed and stripped of all soft tissue after removal of “eyelet” that can hold several sutures and the PushLock threads.
the femur. The pelvis was cut approximately 3 inches © 2010 F. Alan Barber, used by permission.
from the acetabulum to isolate it. Drywall screws were
inserted into the pelvis around each separated acetab-
ulum and then potted in quick-setting resin with care relative to the surface of the acetabulum to allow the
taken to keep the rim free of resin. Six different suture best introduction into the acetabular bone and to avoid
anchors were inserted in rotation into different loca- cutting out of the anchor. The anchors were also
tions on the rim of each acetabulum to decrease the spaced 10 mm apart to leave spacing between anchors
effect of bone quality and density variations in the to avoid crack propagation during the cyclic and de-
different locations (Fig 1). Because different locations structive testing. All the anchors were rotated in po-
of acetabular labral injuries have been reported,8 we sition to place them an equal number of times at the
tested the topographic areas that have been previously different insertion sites. The polyetheretherketone
described as being affected by these kinds of lesions. (PEEK) PushLock anchors (Arthrex, Naples, FL)
The anchors were inserted at the 9-, 10:30-, 12-, 1:30-, were provided with 2 sutures. One of these sutures
3-, and 7:30-o’clock positions in left hips and 9-, was removed so that the PEEK PushLock anchors
10:30-, 12-, 1:30-, 3-, and 4:30-o’clock positions in tested were threaded with a single suture to be con-
right hips. The anchors were inserted at a safe angle9 sistent with the other anchors.
The anchors tested were PEEK PushLock, PEEK
SutureTak, and Bio-SutureTak (Arthrex); Lupine
Loop BR (DePuy Mitek, Norwood, MA); Bio-Mini
Revo (ConMed Linvatec, Largo, FL); and BioRaptor
2.9 AB (Smith & Nephew, Andover, MA). All an-
chors were inserted according to the manufacturers’
instrumentation and recommended techniques.
The PEEK PushLock anchor is a radiolucent, non-
absorbable PEEK 5.5-mm anchor with 2 separate
components (Fig 2). These are the PushLock eyelet
and the PushLock threads, which are premounted and
physically separate on a driver shaft. The closed distal
PEEK “eyelet” is 2 mm wide and can hold several
sutures, a segment of FiberChain (Arthrex), or a single
2-mm FiberTape (Arthrex). The tested version appli-
cable to the hip held a single No. 2 FiberWire suture.
The FiberWire suture is made of a core of multiple
strands of ultrahigh–molecular weight polyethylene
(UHMWPE) surrounded by a braided polyester cov-
FIGURE 1. Six different suture anchors were inserted in rotation into ering. The main body of the anchor is PEEK and has
different locations on each acetabulum rim to decrease the effect of
bone quality and density variations. © 2010 F. Alan Barber, used by a series of 9 ridges with a hollow core through which
permission. the driver shaft passes. After inserting the distal PEEK
764 M. RUIZ-SUAREZ ET AL.

FIGURE 3. The PEEK SutureTak is a 3.0-mm-diameter radiolu-


cent, nonabsorbable PEEK push-in suture anchor with a series of 7
ridges instead of screw threads. © 2010 F. Alan Barber, used by
permission. FIGURE 5. The Lupine Loop BR suture anchor is an absorbable
anchor made of Biocryl Rapide (70% poly-lactide co-glycolide and
30% ␤-tricalcium phosphate) and threaded with a single strand of
No. 2 Orthocord. © 2010 F. Alan Barber, used by permission.
eyelet containing a suture into the hole in the acetab-
ular rim created using the appropriate punch, we ad-
vanced the PushLock threads down the driver shaft
until flush with the bone to secure the suture in the has an entirely different eyelet design (an insert-
bone. molded suture eyelet of braided, nonabsorbable poly-
The PEEK SutureTak is a 3.0-mm-diameter radi- ester suture) and is molded from poly-L-lactide– co-
olucent, nonabsorbable PEEK push-in suture anchor D,L-lactide. A single No. 2 FiberWire suture was
with a series of 7 ridges instead of screw threads (Fig passed through the internal suture eyelet.
3). The single eyelet is located in a traditional post The Lupine Loop BR suture anchor (Fig 5) is an
situated at the anchor top through which a single No. absorbable anchor made of Biocryl Rapide (70% poly-
2 FiberWire suture is passed. A step drill with differ- lactide co-glycolide and 30% ␤-tricalcium phosphate).
ent diameters is used to prepare the insertion site. This Of the poly-lactide co-glycolide in the Biocryl Rapide
anchor should not be confused with the similarly sized material, 85% is poly-L-lactic acid and 15% is poly-
3.0-mm biodegradable Bio-SutureTak (Fig 4), which glycolic acid. This triangular-shaped anchor is 3.9 mm
at the widest part and 9 mm long and is inserted into
a 2.9-mm drill hole. The distal anchor has a slot and
the body a hole. A short knotted suture loop passes
through the hole to hook the slot. This creates an
eyelet through which the single attached suture is
passed. The suture is No. 2 Orthocord (DePuy Mitek)
made from braided absorbable polydioxanone (62%)
and nonabsorbable UHMWPE (38%). The partially
absorbable suture is coated with a copolymer of 90%
caprolactone and 10% glycolide.
Bio-Mini Revo anchor (Fig 6) is a blue, bioabsorbable
3.1-mm-diameter (outer diameter) screw anchor made
from self-reinforced 96L/4D poly-lactic acid. The anchor
is pre-threaded with a single No. 2 Hi-Fi suture (ConMed
Linvatec) made from braided pure UHMWPE. We in-
serted the anchor by first using a 2.1-mm punch to create
a hole in the acetabulum and then a 2.4-mm tap to create
FIGURE 4. The Bio-SutureTak has an insert-molded suture eyelet threads for anchor insertion.
of braided, nonabsorbable polyester suture and a body of molded
poly-L-lactide– co-D,L-lactide. © 2010 F. Alan Barber, used by The BioRaptor 2.9 AB hip suture anchor (Fig 7) is
permission. an absorbable anchor composed of poly-L-lactic acid
SUTURE ANCHORS IN ACETABULAR RIM 765

FIGURE 6. The Bio-Mini Revo anchor is a blue, bioabsorbable


3.1-mm-diameter screw anchor made from self-reinforced 96L/4D
poly-lactic acid with a No. 2 Hi-Fi suture. © 2010 F. Alan Barber,
used by permission.

FIGURE 8. The acetabula were positioned in the Instron machine


material. It has a series of raised ridges that are press so that the sutures of the inserted anchors were pulled in line with
the angle of anchor insertion. © 2010 F. Alan Barber, used by
fit into a 3.0-mm drilled hole. Four ridges are located permission.
proximal and three distal to a single transverse suture
eyelet. The anchor contains a single No. 2 Ultrabraid
suture (Smith & Nephew) made from uncoated, fixture was positioned to create a pull for testing that
braided UHMWPE. For hip arthroscopy, this anchor was in line with the angle of anchor insertion (Fig 8).
comes with a 4.0-mm ⫻ 6-inch drill guide and a A 1-kN load cell was attached to the Instron machine.
4.0-mm obturator. The sutures from the anchors were secured by use of
Biomechanical testing began the same day as an- a pneumatic suture clamp attached to the upward
chor insertion. The potted acetabula were clamped by actuator arm for testing. The clamp was positioned to
an adjustable angle fixture secured to the base of the create a suture gauge length of 30 mm. All anchors
Instron 8871 machine (Instron, Canton, MA), and the were threaded with their own single UHMWPE-
containing suture.
The constructs were preloaded to 10 N at 1 N/s, and
this preload was held for 5 seconds. After preloading,
the constructs were cycled from 10 to 60 N at 1 Hz for
500 cycles.7,10 After cycling, those anchors that sur-
vived the cycling were subjected to a single pull to
failure conducted at 33 mm/s. The data were plotted in
Origin Scientific Graphing and Analysis Software
(OriginLab, Northampton, MA). Cyclic displacement
at 100 and 500 cycles, yield load (start point at fail-
ure), ultimate load, and mode of failure were recorded.
Statistical Analysis
A 1-way analysis of variance test was used to com-
pare means of the data, with significance set at P ⬍
.05. A Pearson correlation analysis was performed to
FIGURE 7. The BioRaptor 2.9 AB hip suture anchor is composed investigate the association between stiffness of the
of poly-L-lactic acid and has 4 ridges located proximal to and 3
distal to a single transverse suture eyelet containing a single No. 2 suture anchor and the cyclic load failure characteris-
Ultrabraid suture. © 2010 F. Alan Barber, used by permission. tics for each anchor.
766 M. RUIZ-SUAREZ ET AL.

TABLE 1. Biomechanical Testing


Anchor Displacement at 100 Cycles (mm) Displacement at 500 Cycles (mm) Ultimate Load (N) Stiffness (N/mm)

Lupine Loop BR 5.2 ⫾ 3.3 5.4 ⫾ 3.3 196 ⫾ 99 28 ⫾ 13


PEEK PushLock 1.0 ⫾ 0.3 1.1 ⫾ 0.4 201 ⫾ 46 112 ⫾ 24
Bio-SutureTak 1.0 ⫾ 0.1 1.1 ⫾ 0.2 177 ⫾ 37 117 ⫾ 16
PEEK SutureTak 1.3 ⫾ 0.8 1.4 ⫾ 0.9 153 ⫾ 26 120 ⫾ 27
BioRaptor 2.9 AB 1.6 ⫾ 1.3 3.4 ⫾ 1.7 166 ⫾ 76 109 ⫾ 33
Bio-Mini Revo 1.6 ⫾ 0.6 1.8 ⫾ 0.6 255 ⫾ 84 78 ⫾ 7

RESULTS 05). The stiffness of the Bio-Mini Revo anchor was


significantly lower than that of the PEEK PushLock,
Most of the displacement observed during cyclic Bio-SutureTak, PEEK SutureTak, and BioRaptor 2.9
loading occurred in the first 100 cycles, except for the AB (P ⬍ .05). No other statistical differences between
BioRaptor 2.9 AB, which showed twice as much stiffness values were found.
displacement at 500 cycles as at 100 cycles. The mean The modes of failure for the various anchors are
cyclic displacement at both 100 cycles and 500 cycles, listed in Table 2. One Lupine Loop BR and one
ultimate load-to-failure strength, and stiffness re- Bio-Mini Revo anchor failed during cycling and did
corded for the anchors tested are listed in Table 1. The not reach the ultimate load-to-failure stage. Others
cyclic displacement of the Lupine Loop BR anchor at were damaged during insertion, reducing the initial
100 cycles was significantly higher than that of the number below 10 for some anchors.
PEEK PushLock (P ⬍ .05). The cyclic displacement The correlation analysis showed no significant
of the BioRaptor 2.9 AB anchor at 100 cycles was mode of association between the suture anchor’s stiff-
significantly greater than that of the PEEK PushLock ness and its cyclic load displacement. The results are
and Bio-SutureTak (P ⬍ .05). No other statistical shown in Table 3.
differences between cyclic displacements at 100 cy-
cles exist.
The cyclic displacement for the Lupine Loop BR DISCUSSION
at 500 cycles was significantly greater than that of This comparison of acetabular labral anchors using
the PEEK PushLock, Bio-SutureTak, and PEEK cyclic loading and load-to-failure testing supports our
SutureTak (P ⬍ .05). The cyclic displacement of the hypothesis that different suture anchors indicated for
BioRaptor 2.9 AB anchor at 500 cycles was signifi- hip arthroscopy would show different biomechanical
cantly greater than that of the PEEK PushLock and characteristics. It should be noted that the Lupine
Bio-SutureTak (P ⬍ .05). No other statistical differ- Loop BR (a common shoulder labral anchor) is the
ences exist for cyclic displacements at 500 cycles. only one in this group of anchors not approved for hip
There were no statistical differences in ultimate labral fixation. It was chosen for testing as an anchor
load-to-failure strength with destructive testing after commonly used for shoulder labral repair. This fact is
500 cycles among any of the anchors (P ⫽ .139).
The stiffness of the Lupine Loop BR anchor was
significantly lower than that of all other anchors (P ⬍ TABLE 3. Correlation Coefficient Between Stiffness and
Cyclic Displacement
TABLE 2. Mode of Failure Pearson Coefficient
(r) for Stiffness/ Pearson Coefficient
No. of Anchor Eyelet Suture Cyclic Load (r) for Stiffness/
Specimens Anchor Pullout Failure Failure Displacement Load to Failure

8 BioRaptor 2.9 AB 6 2 0 Lupine Loop BR ⫺0.12 0.008


8 Bio-SutureTak 4 4 0 PEEK PushLock 0.14 0.23
8 Lupine Loop BR 5 3 0 Bio-SutureTak 0.23 0.15
7 Bio-Mini Revo* 2 5 0 PEEK SutureTak 0.33 ⫺0.69
8 PEEK SutureTak 5 3 0 BioRaptor 2.9 AB ⫺0.46 0.05
8 PEEK PushLock 0 8 0 Bio-Mini Revo ⫺0.21 0.07

*One anchor broke during insertion. NOTE. None of the coefficients showed statistical significance.
SUTURE ANCHORS IN ACETABULAR RIM 767

relevant because it shows that common glenoid an- ever, these failure loads were not statistically differ-
chors cannot be assumed to be appropriate for hip ent.
labral repairs. The Lupine Loop BR was the only All anchors tested were threaded with high-strength
anchor that reached the 5-mm displacement level con- sutures composed either in part or entirely of UHM-
sidered equivalent to clinical failure during cycling. WPE. The cyclic loads were applied directly to these
Although the suture-tissue interface is the greatest sutures, and no case of suture breakage was observed.
area of concern for most soft-tissue repairs, its robust The mode of failure for these anchors was close to
nature makes it unlikely that sutures will pull through evenly divided between anchor pullout from the bone
the acetabular labrum. Consequently, achieving secure and anchor eyelet failure. An exception to this was the
knots and anchors that do not pull out may be more PEEK PushLock, which failed exclusively by the su-
important. Clinical failure may result if a significant ture slipping past the anchor and leaving the anchor
gap develops between the bone and capsulolabral tis- body behind in the bone. Sutures containing UHM-
sue as a result of cyclic loads. WPE have been shown to slip more readily than
In the cuff model, Burkhart et al.11 have shown that conventional braided polyester.12,13 Although the ul-
as few as 25 cycles can cause a 5-mm gap between a timate suture strength is significantly greater than that
rotator cuff tendon edge and the bone and that a of braided polyester, how the UHMWPE-containing
10-mm gap can occur after only 188 cycles. In our suture is secured (knot type or anchor type) may
study almost all of the displacement encountered for influence the most appropriate method of use.
these anchors occurred during the initial 100 cycles Hip arthroscopy is a surgical procedure that is increas-
(Table 1). This is consistent with prior cyclic loading ingly performed worldwide.9,14-20 Labral injuries are one
anchor studies.7,10 The anchor with the largest 100- of the most prevalent lesions found during this proce-
cycle and 500-cycle displacement (Lupine Loop BR) dure.21 Although there is no definite consensus on
whether to repair this type of injury or not, it is
also had 1 failure during cyclic loading, showed the
imperative that the surgeon have a firm understanding
lowest stiffness, and was 1 of the smallest anchors. It
of the characteristics of the implants used for acetab-
was the only anchor in this group not specifically
ular labral fixation and recognize that the differences
indicated for use in the acetabulum, and its perfor-
between acetabular and glenoid bone make anchor
mance in the acetabular environment was clearly dif-
performance different. Biomechanical testing of su-
ferent from the rest. The BioRaptor 2.9 AB is a
ture anchors designated for hip arthroscopy should be
designated acetabular suture anchor, and it alone performed in the acetabular rim before their use. Su-
showed an increase in cyclic displacement between ture anchors used for shoulder arthroscopy may not
the 100-cycle mark and 500-cycle mark, more than perform as well in the hip.
doubling its displacement during that interval. The Strengths of this study include the use of paired
BioRaptor 2.9 AB and Lupine Loop BR displace- human acetabular specimens, the number of tests per-
ments were significantly greater than those shown by formed, the distribution of the anchors among differ-
the PEEK PushLock and Bio-SutureTak (P ⬍ .001). ent testing sites in each of 2 acetabula from the same
Variations in stiffness were also observed (Table 1). individual, and the cyclic loading protocol. These
The Lupine Loop BR anchor showed significantly less specimens were fresh-frozen acetabula with intact la-
stiffness than all other anchors (P ⬍ .001). The Bio- brums. There is little published information about the
Mini Revo anchor stiffness was significantly less than biomechanical properties of suture anchors indicated
that of the PEEK PushLock, Bio-SutureTak, PEEK for use in the hip. This study provides information that
SutureTak, and BioRaptor 2.9 AB (P ⬍ .001). Nev- should be considered when designing rehabilitation
ertheless, it is important to mention that we found no protocols used after an acetabular labrum hip repair.
significant correlation between the suture anchors’ The limitations of this study include the fact that it
stiffness and their cyclic load displacement or load- is an in vitro study and was performed at room tem-
to-failure strength. These data suggest that the design perature in a dry (non-arthroscopic) environment.
of the suture anchor may be more important than its Variations in acetabular bone density within a single
stiffness. specimen do exist, as do variations between speci-
The ultimate loads to failure of many suture anchors mens. In addition, a load to failure in line with the
have been reported. The mean ultimate load to failure angle of anchor insertion may not replicate in vivo
for the anchors tested in this study ranged from 154 N anchor loading. This test does not have direct appli-
(PEEK SutureTak) to 255 N (Bio-Mini Revo). How- cation to the clinical setting for several reasons. The
768 M. RUIZ-SUAREZ ET AL.

cadaveric specimens had ages between 53 and 65 7. Barber FA, Coons DA, Ruiz-Suarez M. Cyclic load testing and
years, which are greater than what would be expected ultimate failure strength of biodegradable glenoid anchors.
Arthroscopy 2008;24:224-228.
clinically for labral repairs. On the other hand, bone 8. McCarthy J, Noble P, Aluisio FV, Schuck M, Wright J, Lee
density may not be significantly different from a JA. Anatomy, pathologic features, and treatment of acetabular
younger population because the acetabular rim is pre- labral tears. Clin Orthop Relat Res 2003:38-47.
9. Hernandez JD, McGrath BE. Safe angle for suture anchor
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