Calcutta National Medical College

3rd Trimester Examination 2023

Subject: Physiology FullMarks: 100
Attempt all questions. The figure in the mugin indicaes full marks
1. A65 years old man, whohas been suffering from hypertension for last 27 years, comes to
Outpatient Department with complaint of reduced urine output despite adequate water intake, s welling
of feet &ap, abdomen, On examunation, his BP is recorded as 220/100 mmHg, he has pedal oedema
and swelling of abdomen. He is adv ised admision &amp. laboratory cxamination of
bloodand urine is carricd out.
rWhat are thc expectecd tindings of hennoglobin, serum urea and creatininc?
b) Explain the mechanism of swelling of legs and abdomen in spite of normal water intake. c) Explain
the physiological basis of steps taken for trcatincnt of the person. d) Why is urine output reduced in
this man? What should be the daily uine produced in a healthy person? 3+5+4+3- 15

L.B How are sensory receptors classitied based on stimulus sourees. What are epicritic and protopathic
senses? Which type of exteroceptors detect these sensations?(Name the two spinal tracts for pain
sensation. ilow are they functionally diferen What is the "gate control theory'" of pain and how is it
put to therapcutic use. 3+2+5+= |5

2Apswer the followíng:

8+2=10
fA Tracethe taste pathway with suitable diagram. What is dysgeusia?
10
B) Describein detail the neuralregulation of respiration. 5+5=10
e. Deseribe the regulation of sccretion and function of insulin hormones.
3.Write short notes on following: 5 2=10
A Eunctions of gastrin
B/Functions of progesteronc
4. Explainfhe following statements: 4 x5=20
weARelaxation of skeletal múscie is active process.
he Na/K pump regulates cellvolume
Creatinine clearance is uscd to mcasure GFR
D) Prothrombintime is rarely prolonged in hemophilics with adeficiency of factors IX or VII.
The corpus striatum has no conncetions with the spinalcord and yet, it controls motor
functions.
5.Chose the correct option of each of the following: 1x10=10
1. The effect of stimulating sympathctic nerves to the urinary bladder is:
A. Increcase tone of the muscle of the bladder
B. Altcration of blood flow
CRelaxation of internal vesical sphincter
5. Contraction of internal sphincter and withholding urine in urgency.
2. Saltatory conduction in myclinatcd axons results from the fact that
A. Salt concentration is increased bencath the myelin segments
B. Nongated ion channels are present bencath the segment of myelin
C. Membrane resistance is decreased beneath the segments of myelin
D Voltage gated sodiumchannels ane concentrated at the node of Ranvier
3.Simple diffusion and facilitated ditfusion share which of the following characteristics?
A, Canbe blocked by specific inhibilors
B. Do not require adenosine triphosphate (ATP)
C. Require transporl protein
D. Saturation kinetics
4 Which condition at heA-V node will cause a decreasein heart rale?
A. Increased sodium permeabi!ity
B. Decreased acetylcholine levels
C. nereased norepinephrine levels
\D Inereased potassium perineability
5. Which phagocytes can extrude digestion products andcontinue to survive and function for many
months?
A. Neutrophils
B. Basophils
Le Macrophages
D. Eosinophils
liters, VT of 650 milliliters, ERV of 1.5
6.A patient has a dead space of 150 milliliters, FRC of 3 What is the alveolar ventilatIon (Va)?
breaths/min.
liters, T of 8liters, and respiratory rate of 15
/sL/min
B. 7.5 L/min
C. 6.0Lmin
D. 9,0 Lmi
receptor found in the dermis of hairy
7Which of the following best deseribes an c% panded tip tactile
skin that is specialized to detect continuously applicd touch sisation?
A. Free nerve endings
B. Merkel disc
C. Pacinian corpuscle
D Ruttini endings
8 Which substance will elicit the sensation of bitter taste?
A. Aldehydes
LB, AIkaloids
C. Amino acids
D. Hydrogen ions steroid?
9. Thecal cells in the follicle are not able to produce what sex
A. Estradiol
B. Testosterone
C. Progesterone
D Dihydrotestosteron secretion?
10.Wsubstances are most !ikely to produce the greatest increase in insulin
A. Amino acids
LB. Amino acids and glucose
Amino acids and somatostatin
D. Glucose
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a
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