Pathology Quiz Final

Renal Pathology

Question 1

Adult polycystic kidney is associated with all EXCEPT:

hematuria

shrunken cystic kidneys

hepatic cysts

hypertension

Question 2

Medullary sponge kidney is best described as a condition with:

death from renal failure before 40 years of age

presentation usually in childhood

usually normal renal function

uniform 2-cm renal cysts

Question 3

Renal medullary cystic disease is characterized by:

present in middle adult life

congenital urethral obstruction

 infantile polycystic kidney disease

present with renal failure

Question 4
Chronic pyelonephritis is characterized by:

swollen scarred kidney

chronic inflammation in tubulointerstitial area and calyces

disordered mesenchyme, cartilage and tubules

ongoing renal papillary necrosis

Question 5

A renal biopsy shows the following findings: hypercellularity due to mesangial

and endothelial cells, neutrophils, subepithelial electron-dense hump-like
deposits; IgG and C3 in the deposits. The most likely diagnosis is:

acute post-strep GN

rapidly-progressive GN

lupus nephritis

bacterial endocarditis

Question 6 (1 point)

An autopsy is performed in an elderly male and the kidney shows interstitial

fibrosis, chronic inflammation, papillary necrosis. Probable causes are the
following EXCEPT:

analgesic abuse
 essential HPN

benign prostatic hyperplasia (BPH)

diabetes mellitus

Question 7

A patient has abruptio placenta during the third trimester and eventually dies.
Which of the following kidney findings would most likely show on autopsy?

renal artery stenosis

horseshoe kidney

acute pyelonephritis

renal cortical necrosis

Question 8

All of the following are mediators of glomerular injury EXCEPT:

tubular cells

Neutrophils

NK cells

resident glomerular cells

Question 9

The most important morphologic feature of rapidly progressive GN is:

small deposits of fibrin within capillary lumen

enlarged hypercellular glomeruli

proliferation of epithelial cells with migration of monocytes, macrophages into the

Bowman’s space

small contracted kidneys with petechial cortical hemorrhages

Question 10

Histologically, the following lesions are seen in the kidneys in diabetes mellitus EXCEPT:

benign nephrosclerosis

Kimmelstiel-Wilson disease

uric acid nephropathy

Acute pyelonephritis
FGT Quiz

Question 1

Which of the following is the LEAST likely cause of abnormal uterine bleeding in a
29-year-old woman?

Anovulation

Chronic endometritis

Endometrial atrophy

Leiomyoma

Question 2

Which of the following features is considered characteristic of chronic

endometritis?

Eosinophils

Granulomas

Lymphoid aggregates

Plasma cells

Question 3

When a diagnosis of chocolate cyst of the ovary is made by a pathologist, this

refers to:

hemorrhagic infarction of an ovarian cyst secondary twisting of its pedicle

endometriosis
 serous cystadenoma with intracystic hemorrhage

hemorrhagic corpus luteum cyst

Question 4

Most frequent site for ectopic pregnancy is the:

pelvic peritoneum

uterine cervix

fallopian tube

Ovary

Question 5

Earliest evidence of ovulation as reflected in the endometrium:

intraluminal secretion

secretory exhaustion

subnuclear vacuolation

predecidual changes around the arterioles

Question 6

A 60-year-old woman presents with a 3-week history of a painful genital lesion

and bleeding. Physical examination reveals an exophytic, ulcerated 1-cm polypoid
mass near the external end of the urethra. What is the most likely diagnosis?

Bartholin gland cyst

Condyloma acuminatum

Lichen sclerosis

Lymphogranuloma venereum

Question 7

A 36-year-old woman presents with infertility. She complains of having had dull
pelvic pain for 9 months, which is accentuated during menstruation. Physical
examination and endocrinologic studies are normal. Laparoscopy reveals multiple,
small hemorrhagic lesions over the surface of both ovaries and fallopian tubes and
abundant pelvic scarring. Which of the following is the most likely diagnosis?

Ectopic pregnancy

Borderline serous tumor

Endometriosis

Metastatic cervical carcinoma

Question 8
A 58-year-old woman complains of recent swelling in her vagina. There is a past
medical history of prenatal exposure to diethylstilbestrol. Physical examination
reveals a 3-cm firm mass in the anterior wall of the upper vagina. Biopsy of the
vaginal mass will most likely show which of the following pathologic findings?

Clear cell adenocarcinoma

 Endodermal sinus tumor

Granular cell tumor

Mucinous adenocarcinoma

Question 9

A 59-year-old woman presents with a 2-year history of vulvar itching and burning.
Physical examination reveals a red, moist lesion of the labium major. Biopsy
reveals clusters of pale vacuolated cells within the epidermis that stain positively
for periodic acid-Schiff (PAS) and carcinoembryonic antigen (CEA). Which of the
following is the most likely diagnosis?

Extramammary Paget disease

HPV-induced papilloma

Verrucous carcinoma

Vulvar intraepithelial neoplasia

Question 10

A 35-year-old woman presents with a 6-week history of vaginal discharge, which is

occasionally blood tinged. Pelvic examination reveals a 2-cm pedunculated,
lobulated, and smooth cervical growth; it is excised. Histologic examination of the
specimen would most likely reveal which of the following?

Condyloma acuminatum

Embryonal rhabdomyosarcoma

Endocervical polyp

Leiomyosarcoma