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Review Article
*Corresponding Author Abstract: Food poisoning is a common disease condition that usually results from
Dr. Nagham Mahmood
eating food contaminated with infectious microorganisms (viral, bacterial, parasitic
Aljamali
or fungal) or toxins secreted during the different stages of food processing,
Article History production or preservation. Most cases of food poisoning are considered moderate
Received: 16.09.2021 and their symptoms resolve spontaneously within several days without treatment,
Accepted: 27.10.2021
while severe and chronic cases require hospitalization. Food poisoning can usually
Published: 01.11.2021
be prevented by keeping hands clean and preparing food in proper, hygienic and
clean ways. The majority of reported cases of foodborne illness are individual or
sporadic. The origin of this sporadic infection often cannot be determined. For
example, the majority of foodborne disease outbreaks (58%) in the USA originate in
commercial food establishments (Foodnet 2004 data). An outbreak is defined as
when two or more people are exposed to the same disease after eating food from a
common food supply. There is often more than one reason for an outbreak or
outbreak, for example, food may be left at room temperature for many hours,
allowing the growth of bacteria that accumulate through inadequate cooking of the
food, resulting in failure to eliminate or kill Bacteria levels are very dangerous.
Keywords: Poisoning, toxicity, diaries, pollution, diarrhea, bacteria, fungi, parasitic.
Copyright © 2021 The Author(s): This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International
License (CC BY-NC 4.0) which permits unrestricted use, distribution, and reproduction in any medium for non-commercial use provided the original
author and source are credited.
of the public consuming these foods. We see that strong and only cause problems with prolonged
cases of food poisoning in general are limited in exposure or frequent use of large amounts of the
developed countries, and widespread in poor poison. Others are so potent that a drop on the skin
countries [12]. Food preparation shops have the can cause severe symptoms. Some toxins cause
greatest responsibility towards the consumer by symptoms within seconds, while others cause
purchasing meat from approved and experienced symptoms only hours, days, or even years later.
food preservation places, and these stores must also Some toxins cause such obvious symptoms that vital
provide the necessary equipment for preserving organs, such as the kidneys or liver, are sometimes
meat in particular and other types of food in general. permanently damaged. Ingested (ingested) and
In order to prevent the proliferation of bacteria, absorbed toxins cause symptoms throughout the
which often need moderate temperatures for body because they often deprive the body's cells of
growth, as well as paying attention to places of oxygen or activate or block the action of enzymes
preparation in terms of sanitation, and general and receptors. Symptoms may include changes in
hygiene, as well as paying attention to workers in consciousness, body temperature, heart rate and
terms of education regarding food poisoning and breathing, and a number of other symptoms,
physical hygiene, washing hands well after depending on which organs are affected. Caustic or
defecation, and keeping patients away from the irritating substances Injury to the mucous
preparation process, especially those Who complain membranes of the mouth, throat, digestive tract, and
of stomach flu. Not leaving foods exposed or exposed lungs causes pain, coughing, vomiting and shortness
to insects or hot weather for long periods, using of breath [19, 20]. Skin exposure to toxins can cause
gloves when touching foods, getting rid of old foods various symptoms, such as rashes, pain, and blisters.
on a daily basis, not mixing old foods with fresh Also, prolonged exposure to toxins can cause skin
ones, especially getting rid of foods that change their inflammation. Eye exposure to toxins can damage
color, taste or smell, and a sense of responsibility the eye, causing eye pain, redness, and decreased
towards consumers and not acting out of purely vision [21].
materialistic [13, 14].
Bacteria
Deliberate poisoning Bacteria is one of the main underlying
Poisoning may be a deliberate attempt to causes of foodborne diseases. Where the bacteria
kill or commit suicide. Most adults who attempt involved in the infection of such diseases in the
suicide by poisoning use more than one drug and United Kingdom in 2000 were examples:
also drink alcohol. Poisoning can be used to weaken Campylobacter jejuni by 77.3%, Salmonella by
a person (for example, to rape or rob a person). In 20.9%, and E. coli O157:H7 by 1.4%, while other
rare cases, parents with a mental disorder poison types of bacteria represented no more than 0.1 % of
their children to make them ill, thereby gaining the underlying causes of foodborne diseases. It used
medical attention (a disorder called Factitious to be that bacterial infection was more common
Disorder). Foodborne diseases often result from because only a few places were able to test for
poor handling, improper preparation and norovirus, and passive surveillance for that agent
processing, and poor food storage. Noting that good was done. Noting that the symptoms of a bacterial
hygiene practices before, during and after food infection are delayed because the bacteria need a
processing reduce the chances of exposure to period of time to multiply. It is often hidden and not
foodborne diseases. A common awareness trend seen until 12-72 hours or more after eating the
among the public health community is that regular contaminated food among the most common
hand washing is one of the most effective defenses bacterial pathogens are:
against the spread of foodborne diseases. This
movement to control and control food to ensure that Campylobacter jejuni, which leads to a
it does not cause exposure to foodborne diseases is secondary form of Guillain-Barré syndrome and
known as food safety. This makes the underlying periodontitis. Clostridium perfringens, which is
cause of exposure to foodborne diseases a wide called the "cafeteria germ".
variety of toxins affecting the environment. For
more information on chemical-borne diseases, see Salmonella - Eating eggs that have not been
Food contamination. Foodborne diseases can also be cooked enough causes typhimurium infection, or
caused by pesticides or medicines in foods, in other pathogens that are transmitted between
addition to natural toxic substances, including humans and animals [22-25].
poisonous mushrooms or reef fish [15-18].
Symptoms Salmonella
Symptoms of poisoning vary depending on Escherichia coli
the poison, the amount used, the age, and the health O157:H7enterohemorrhagic causes hemolytic-
of the person using it. Some poisons are not very
© 2021: Global Academic Journal’s Research Consortium (GAJRC) 56
Nagham Mahmood Aljamali et al., Glob Acad J Pharm Drug Res; Vol-3, Iss- 4 (Nov-Dec- 2021): 54-61
µg/kg in solid fruit products and 10 µg/kg in baby location of the ingested substances. Toxins that may
food. be visible on x-rays include iron, lead, arsenic, and
phomopsin other metals, and large packets of cocaine or other
sporidismin A prohibited drugs swallowed through so-called body
stigmatocystin pounders or drug carriers (see Body Filling and
Body Filling). Batteries and magnets can also be
Tremorgenicmycotoxins - Five types of distinguished on x-rays, as well as canines, teeth,
tremorgenicmycotoxins have been reported to be cartilaginous spines, and other animal parts that
found in fermented meat. They are: Fumitremorgen may disintegrate and remain as an integral part of
B, Paxilline, Penitrem A, Verrucosidin, and the body after an animal attack or exposure to insect
Verruculogen Trichothecenes - Its sources are venom[37].
Cephalosporium, Fusarium, Myrothecium, Stucky
botris and Trichoderma. The toxins are usually Natural toxins
found in rotting corn, wheat, peanuts, and rice, as Many foods naturally contain toxins, most of
well as animal feed straw and hay. Both humans and which are not caused by bacteria. Plants in
animals suffer from four common types of particular can be poisonous; While animals are
Trichothecenes toxins: T-2 toxin, HT-2 toxin, rarely naturally poisonous. Evolutionarily speaking,
diacetoxyscirpenol (DAS) and deoxynivalenol animals have the ability to escape if they are preyed
(DON). Oral administration of these toxins upon or eaten; However, plants use only negative
subsequently results in toxic and foodborne defense techniques, including toxins and revolting
leukopenia, as well as hematological disorders, substances that taste bad, such as capsaicin in chili
aplastic anemia, thrombocytopenia and/or peppers and pungent sulfur compounds in garlic and
irritation. Skin. This prompted the US Food and Drug onions. Noting that the majority of animal toxins are
Administration to issue a document in 1993 that not made by animals themselves, but they acquire
limits the content of deoxynivalenol in human foods them by eating poisonous plants to which these
and animal feeds as an indicative. The United States animals are immune to their toxicity, or by the
of America has also published a promising patent for action of bacteria. The harmful activity of these
farmers to produce trichothecene-control crops. bacteria in the digestive system is due to
Zearalenone enterotoxins, which are divided into two groups,
Zearalenols exotoxins (toxins secreted from microorganisms
into the surrounding environment) and endotoxins
Diagnosis (which remain inside the cells of microorganisms
Determining the poison, sometimes urine and are released when cells are destroyed).
and blood tests, x-rays of the abdomen In rare cases, Exotoxins are released mainly by Gram-positive
knowledge of the poison is useful for treatment. The bacteria during their growth. They are made up
labels on the bottles and other information from the mostly of very toxic and antigenic proteins that
person, family members, or co-workers make it become active after a quiescent period. This group
easier for the doctor or poison center to identify includes toxins released by Clostridium botulinum
poisons. However, if labels are not available, the (botulin toxin, a neurotoxic globular protein), C.
drugs can often be identified by the markings and perfringens and Staphylococcus aureus. Poisoning
colors on the tablets or capsules. It is highly unlikely with St. aureus is the most common food poisoning,
that laboratory tests can identify the toxin, since and its symptoms include vomiting, diarrhea,
many drugs and toxins cannot be easily identified or stomach pain, and its main cause is food of animal
their levels measured in the hospital. However, origin, meat and its products, poultry, cheese, potato
blood and urine tests can sometimes help identify salad, and pastries). The basis of endotoxins from
the toxin. Sometimes blood tests can reveal the Gram-negative bacteria, they act as antigens and
severity of the poisoning, but these tests are limited bind tightly to the cell wall of bacteria and are
to a few toxins [34-36]. Doctors examine people for complex in nature, consisting of protein,
signs of a particular type of substance. For example, polysaccharides, and lipids. Endotoxins are
doctor’s check for needle marks or track for signs relatively stable thermally, and are generally active
that these people have injected drugs (see Using without requiring an incubation period. The toxins
Injectable Drugs). They also test people who have that cause typhoid and paratyphoid, salmonellosis
symptoms characteristic of certain types of and bacterial dysentery are of this group.
poisoning. Doctors look to see if people have traces Salmonellosis is very dangerous and is an infection
of a drug or substance on their skin, or whether drug with toxins numbering about 300 species: but they
labels for drugs absorbed through the skin are are closely related organisms. The infection is
hidden in skin folds, on the roof of the mouth, or characterized by internal fever, gastroenteritis, and
under the tongue. In some cases of poisoning, an salmonellosis septicemia: the sources of infection
abdominal x-ray may show the presence and are different, but they are closely related organisms.
The infection is characterized by endogenous fever, slicer in an Aberdeen food store, and because of the
gastroenteritis and salmonellosis septicemia: egg poor cleaning procedures of the machine, the
products, frozen poultry, ground beef, candy contamination spread to the meat stored in other
products and coca are sources of infection [38]. The boxes that were cut using the same machine. The
presence of E. coli bacteria first indicates the people of Aberdeen then ate the contaminated meat,
presence of fecal contamination, and this gives became infected and became ill. Foodborne disease
special attention. This bacterium introduces an outbreaks during the seventies of the twentieth
endotoxin strain, a particularly dangerous strain century prompted the United Kingdom to bring
that was discovered in 1983. about fundamental and drastic changes in food
safety law in the Kingdom of Britain. These
Prevention of bacterial food poisoning outbreaks included the deaths of about 19 patients
Proper frozen storage of foods helps in an outbreak that occurred at Stanley Royal
prevent food poisoning. Prevention is often the role Hospital [43] in the 1980s. And about 17 deaths in
of government, by setting strict rules for health and 1996 in Wishu from infection with E. coli O157,
public services for veterinary surveys of animal which was an indication for the establishment of the
products in the food chain, from the agricultural Food Standards Agency, which according to the
field to manufacturing and delivering products to comment of former British Prime Minister Tony
supermarkets and restaurants. Here, the organizing Blair in 1998 that the white document [44,45]: A
process includes: Traceability: the origin of the Force for Change Cm 3830 It will have executive
ingredients in the final product must be known authority and power, as well as be open and
(whether from the parent farm from which the oriented to serve the interests of consumers.
ingredients were collected, by identifying the crop or
animal sources) and where and when they were CONCLUSIONS
processed; Then the source of the disease can be Food poisoning, also known as foodborne
found, traced, and then try to find solutions to treat illness, is an illness caused by eating contaminated
it (and it may be possible to punish the responsible), food. Infectious germs, including bacteria, viruses,
in addition to providing the opportunity to dispose and parasites, or their toxins, are the most common
of the final products and withdraw them from the cause of food poisoning. Infectious germs and their
market if a problem is proven; Implementation of toxins can contaminate food at any stage of
sanitary procedures including HACCP and “cold processing or production. Contamination can also
chain” certification standards; Control, control, occur in the home if food is prepared or cooked
deterrence and law enforcement authority for incorrectly. Symptoms of food poisoning, which can
veterinarians. In the year 2006, the US Food and begin within hours of eating contaminated food,
Drug Administration in the United States of America often include nausea, vomiting or diarrhea. Often,
adopted the methodology of phage therapy, which food poisoning is mild and goes away without
includes spraying meat with viruses that infect treatment. But some patients need to go to hospital.
bacteria, thus preventing the spread of infection.
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