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  • Obstructivejaundice 160724040224

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    Lola Cassandra Cherita
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    Obstructive jaundice can be caused by intraluminal, mural, or extrinsic blockage of the biliary tract. The document discusses the anatomy of the biliary tract and the physiology of jaundice. Labs for obstructive jaundice show increased total and direct bilirubin, as well as elevated alkaline phosphatase and GGT levels. There is also dark urine due to conjugated bilirubin and no urobilinogen due to obstruction of bilirubin entering the bowel. An algorithm is used to diagnose obstructive jaundice.

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    Obstructive jaundice can be caused by intraluminal, mural, or extrinsic blockage of the biliary tract. The document discusses the anatomy of the biliary tract and the physiology of jaundice. Labs for obstructive jaundice show increased total and direct bilirubin, as well as elevated alkaline phosphatase and GGT levels. There is also dark urine due to conjugated bilirubin and no urobilinogen due to obstruction of bilirubin entering the bowel. An algorithm is used to diagnose obstructive jaundice.

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    © All Rights Reserved
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    4 views10 pages

    Obstructivejaundice 160724040224

    Uploaded by

    Lola Cassandra Cherita
    Obstructive jaundice can be caused by intraluminal, mural, or extrinsic blockage of the biliary tract. The document discusses the anatomy of the biliary tract and the physiology of jaundice. Labs for obstructive jaundice show increased total and direct bilirubin, as well as elevated alkaline phosphatase and GGT levels. There is also dark urine due to conjugated bilirubin and no urobilinogen due to obstruction of bilirubin entering the bowel. An algorithm is used to diagnose obstructive jaundice.

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    © All Rights Reserved
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    of 10

    OBSTRUCTIVE

    JAUNDICE

    INTRODUCTION

    Dr.B.Selvaraj MS;Mch;FICS;
    Professor Of Surgery
    Melaka Manipal Medical college
    Melaka 75150 Malaysia
    Must to know core clinical
    problems
    1.Acute RLQ pain 10.Breast lumps, mastalgia & nipple discharge
    2.Acute RUQ pain 11.Neck swellings- Thyroid & non thyroidal
    3.Acute epigastric pain 12.Groin swellings
    4.Acute LLQ pain 13.Scrotal swellings
    5.Dysphagia 14.Limb ischemia- Acute & Chronic
    6.Abdominal lumps 15.Varicose veins
    7.Upper GI haemorrhage 16.Renal & ureteric colic
    8.Lower GI haemorrhage 17.Hematuria
    9.Obstructive Jaundice 18.Acute retention of urine
    Obstructive Jaundice- Introduction

    Causes of obstructive jaundice


    Anatomy of biliary tract
    Physiology of jaundice
    Labs in obstructive jaundice
    Algorithm in obstructive jaundice
    Obstructive Jaundice- Causes
    • Intraluminal causes:
    - Choledocholithiasis
    - Clonorchis sinensis
    - Ascariasis & Schitosomiasis
    • Mural causes:
    - Malignant stricture-cholangiocarcinoma
    - Benign stricture- Scelerosing cholangitis
    • Extrinsic Causes:
    - Ca Head of Pancreas
    - Periampullary Carcinoma, Portal LN
    Anatomy of Biliary Tract
    Physiology of Jaundice
    Labs in all types of Jaundice
    Labs in Obstructive Jaundice

    Bilirubin in the urine (characteristic Increased total bilirubin and direct


    dark colouration) this occurs as the bilirubin(conjugated bilirubin)
    bilirubin is conjugated and thus  Increased canalicular enzymes: alkaline
    water-soluble phosphatase and GGT
    No urobilinogen in the urine; due to Increased liver enzymes ALT and AST;
    the obstruction, no bilirubin enters not as significant as seen in
    the bowel to be converted to hepatocellular causes, but biliary
    urobilinogen.
    backpressure inevitably leads to mild
    hepatocyte damage.
    Obstructive Jaundice-
    Diagnostic Algorithm
    THANK YOU
    To watch the video version go
    to:
    youtube.com/c/surgicaleducator

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