ALLIED HEALTH SCIENCES

GENERAL PATHOLOGY

Approved by ; DR RAJIA LIAQAT

Associate Professor Pathology
MBBS, FCPS
Al Aleem Medical College /GDTH

1st year(CPT,MLT,ICU,OTT,RT) Pathology

STUDY GUIDE

1st year(CPT,MLT,ICU,OTT,RT) will study General Pathology topics outlined in the curriculum his
study guide.

 RATIONALE

a. To set the standards required by University of Health Sciences..

 b. To ensure that medical lab technologists are prepared to provide high quality service in
laboratories

 CONTENT OF LEARNING

1. The curriculum details the level of knowledge, its application, skill and professional behavior
that a student should acquire and demonstrate in practice to provide a high-quality service in
laboratories

2. Throughout the year students are given responsibility and independence appropriate for their
level of competence and professional development, as judged by their teachers and
facilitators.

 DURATION: Students will study General pathology for approx 38 weeks according to the
planned academic curriculum followed by their assessments.

 FACILITATOR: Dr Rajia Liaqat LECTURERS: Dr Nida Javed , Mr Nasir Faruq

 NO OF LECTURES; 2 per week DURATION OF LECTURE; 45min

 NO OF TUTORIALS; 1 per week DURATION OF TUTORIAL; 45min

 TEACHING METHODOLOGY; Interactive lectures.

 VENUE; Chest Auditorium

 MODES OF ASSESSMENT: Assignments, MCQs and Presentations

 LEARNING RESOURCES ; ROBBINS BASIC PATHOLOGY New edition, Lectures

GENERAL PATHOLOGY

Week Topic Learning Objectives Tutorial MIT (Mode of

Information transfer)/
Educational strategy
CELL INJURY At the end of this week,
student will be able to: Cellular Lectures
Week 1 adaptations Tutorial
1.Introduction to a) Define basic pathology (Hypertrophy,
pathology terminologies and discuss hyperplasia,
cellular adaptations. metaplasia,
atrophy)
b) Explain Etiology,
 2. Cellular adaptations Pathogenesis/
(Hypertrophy, Mechanism
hyperplasia, andMorphology of
metaplasia, atrophy) cellular adaptations.

At the end of this week,

student will be able to: Lectures
Irreversible cell Tutorial
Week 2 Explain Etiology, injury
Irreversible cell injury.
Mechanisms,
Morphological
alterations and
Clinico pathological
correlations of types of
injuries.

At the end of this week,

student will be able to:
Week 3 Reversible cell Lectures
Reversible cell injury Categorize types of injury Tutorial
injury and discuss
mechanisms involved in
Reversible injury and
differentiate from
irreversible cell injury.

At the end of this week,

Apoptosis student will be able to: Lectures
Week 4 & Apoptosis Tutorial
Necrosis a) Define apoptosis and & Necrosis
necrosis.
b) Explain mechanisms
involved in both,
Etiology, Types,
Mechanism,
Morphology correlations
of Apoptosis and
Necrosis.

1.Intracellular At the end of this week,

accumulations & student will be able to: Intracellular Lectures
Week 5 pigmentations accumulations, Tutorial
a) Categorize types of
2. Pathological cellular accumulations, Pathological
calcification calcification
 & aging elaborate pathological
calcification and aging.
b) Give Classification,
Mechanisms of
intracellular
accumulations and
pigmentations.

Week 6 Students At the end of this week Cell injury Presentations

Presentation student will be able to: &
Adaptations

Week 7 TEST 1
cell
injury & adaptations
INFLAMMATION, At the end of this week,
MEDIATORS OF student will be able to: Vascular
Week 8 INFLAMMATION a) Discuss Role of changes of
1. Role of inflammation in the acute Lectures
inflammation in the defense mechanisms of the inflammation Tutorial
defense mechanisms body.
of the body. b) Describe Vascular
2. Vascular changes changes in acute
of acute inflammation to
inflammation and morphological features and
their relation to its tissue effects.
morphological and c) Classify, explain
tissue effects Etiology,
Mechanism and
of vascular changes.

1.Role of cellular At the end of this week,

Week 9 components in student will be able to:
inflammation Mediators Lectures
a)Discuss role of cellular of Tutorial
components in inflammatio
2. Chemical mediators inflammation. n
of b) EnlistChemical
inflammation,Arachid mediators of
onic acid metabolism, inflammation.c)
Role of products of Explain Arachidonic
Arachidonic acid acid metabolism, Role
of products of
 metabolism in Arachidonic acid
inflammation. metabolism in
inflammation.
At the end of this week,
Week 1.Acute student will be able to:
10 inflammation Chronic
a) Elaborate inflammatio Lectures
Morphological patterns n Tutorial
and outcomes of acute
2.Chronic and chronic
inflammation inflammation.
b) Discuss Types,
causes, mechanism,
clinical features and
outcomes of acute and
chronic inflammation.

At the end of this week,

1.Granulomatous student will be able to:
Week 11 inflammation Inflammatio Lectures
Explain n Tutorial
2.Revision Etiopathogenesis and assessment
Morphology of
Granulomatous
inflammation.

Week 12 Student
Presentations on
Inflammation
Week 13 TEST 2
Inflammation
Week 1st term assessment
14, 15

At the end of this week,

Week 16 WOUND student will be able to: Cell cycle Lectures
HEALING
1. Repair and a) Define wound Tutorial
regeneration. healing.
2. Cell cycle b) Discuss
Mechanisms of repair
and regeneration.
 At the end of this week, Lectures
1.Wound healing by student will be able to: Tutorial
first and second Cutaneous
Week 17 intention. a) Explain Wound wound
healing by first and healing
second intention.
b) Explain Etiology and
Pathogenesis of
wounds.
c) Enlist Clinical
features and
Morphology of wound
healing.

Week 18 Factors that At the end of this week, Factors Lectures

influence wound student will be able to: affecting Tutorial
healing Enlist Factors that wound
influence wound healing
healing.

At the end of this week, Lectures

Week 19 1.Complications of student will be able to: Complicatio Tutorial
wound healing ns of wound
a) Enlist Complications healing
of wound healing
b) Elaborate
Mechanism and
Morphology of various
wound complications.
Week 20 Student
Presentations
Wound healing
Week 21 TEST 3; healing &
repair

DISORDERS OF At the end of this week, Lectures

CIRCULATION student will be able to: Tutorial

Week 22 1. Thrombosis. a) Explain Thrombosis. Thrombosis

2. Consequences of b) Describe its
thrombosis Etiology, Types,
Pathogenesis,
Morphology and
Consequences.
 At the end of this week,
1. Embolism student will be able to: Embolism Lectures
Week 23 2.Difference Tutorial
between arterial and a) Classify various
venous emboli types of emboli and
differentiate between
arterial and venous
emboli.
b) Explain
Classification,
Etiology,
Clinical features and
Morphology of emboli.
At the end of this week,
Week 24 1.Hemorrhage, student will be able to: Lectures
Hyperemia, edema, Infarction Tutorial
congestion. a) Discuss Hemorrhage,
Hyperemia, edema and
congestion
2.Infarction b) Elaborate Infarction
and describe their
Etiology,
Types,
Pathogenesis and
Morphology.

At the end of this week,

Week 25 1.Shock student will be able to: Lectures
2. Compensatory Tutorial
mechanisms a) Categorize various Shock
involved in shock Types of shock and
elaborate
Compensatory
mechanisms involved in
shock.
b) Discuss their Types,
Causes and
Clinicopathological
features

Week 26 Students
Presentation;
Disorders of
circulation
Week 27 TEST 4; Disorders .
of circulation

Week 28 Assessment 2nd

term
Week 29 GROWTH At the end of this week, Nomenclatur
DISORDERS / student will be able to: e
NEOPLASIA & difference Lecture
1.Classify benign & between Tutorial
Introduction of malignant tumors benign and
neoplasia malignant
2. difference benign and neoplasm
malignant neoplasm

Week 30 At the end of this week,

1.Etiology of student will be able to: Etiology of Lecture
neoplasia neoplasia Tutorial
1.Describe
2. Pathogenesis etiopathogenesis of
neoplasm.

Week 31 1.Grading of tumors At the end of this week, Grading & Lecture
2.Staging of tumors student will be able to: staging Tutorial

Differentiate between
grading and staging of
tumors

Week 32 Tumor markers At the end of this week, Tumor

student will be able to: markers
Lecture
1.Define tumor markers Tutorial
2.Enlist tumor makers

Week 33 Student
presentations
Neoplasia
Week 34 TEST 5; Neoplasia
Week Sendup exam
35, 36