3rd MODULE

SYLLABUS

SECOND YEAR BDS

ACADEMIC YEAR 2023-24

 MODULE DETAILS
Course BDS Year Second
Duration of each module 08 weeks
Learning outcomes The competent medical practitioner,
skillful & knowledgeable
Module assessment End-module assessment
Assessment methods BCQs
SEQs,
OSPE
VIVA

THE MODULE COMMITTEE:

Module integration committee is comprised of members from all the faculties.

MODULE COORDINATOR
Dr Doha Rajar lecturer community dentistry

COMMITTEE MEMBERS

1. Dr Faiz khoso Assistant Professor Department of Oral Pathology

2. Dr Hafiz Mehmood Associate Professor Science of dental material
3. Dr Sujaullah Assistant Professor Department of Pharmacology
 BDS MODULE III
THEME S OF NEOPLASIA, HAEMODYNAMICS & GENETICS MODULE

This educational module is divided into two segments, each spanning 8 weeks, resulting in a
total duration of 16 weeks. The primary objective of these segments is to facilitate
comprehensive learning in essential subjects, such as GENERAL PATHOLOGY, MICROBIOLOGY,
PHARMACOLOGY, AND ORAL PATHOLOGY, with a specific thematic emphasis.
THEME DURATION
NEOPLASIA WEEK 1 to 3
HAEMODYNAMICS WEEK 4 to 5
GENETICS WEEK 6 to 7

OBJECTIVES OF MODULE III:

THEME I: NEOPLASIA

1. Understanding the fundamental concepts of neoplasia, including the etiology, pathogenesis, and
classification of neoplastic diseases.

2. Recognizing the specific types of neoplasms that can occur in the oral cavity and their clinical
manifestations.

3. Exploring the principles of tumor diagnosis and assessment, such as biopsy techniques and imaging
modalities.

4. Investigating the molecular and cellular mechanisms underlying neoplastic growth and progression.

5. Identifying the risk factors associated with oral and systemic neoplastic diseases and their potential
preventive measures.

6. Explaining the principles of cancer treatment, including surgery, radiation therapy, chemotherapy,
and targeted therapies, and understanding their indications and side effects.

7. Evaluating the role of pharmacological agents in the management of neoplastic diseases, including
chemotherapy drugs, targeted therapies, and their mechanisms of action.

8. Discussing the potential interactions between drugs used in neoplasia treatment and their
implications for dental and oral healthcare.

9. Analyzing case studies and real-life scenarios to apply the knowledge gained in the neoplasia topic to
clinical practice.

10. Promoting awareness of the importance of early detection and prevention of neoplastic diseases in
oral and systemic contexts.

THEME II: HEMODYNAMICS

1.To grasp the fundamental principles of hemodynamics, including concepts like blood flow,
pressure, and resistance in the context of oral health.

2. To establish the connection between hemodynamic disturbances and oral diseases, such as
vascular lesions, bleeding disorders, and their clinical manifestations.

3. Develop the ability to identify and diagnose oral lesions or conditions related to altered
hemodynamics through clinical examination and diagnostic tools.
4. Explore the pathological mechanisms underlying hemodynamic disorders, such as
inflammation, thrombosis, and atherosclerosis.

5. Understand how hemodynamic changes can affect different organ systems, including the
heart, blood vessels, and other vital organs.

6. Investigate the association of hemodynamic disturbances with various pathological

conditions, like hypertension, aneurysms, and ischemic heart disease.

7. about pharmacological interventions used to treat hemodynamic disorders, including

antihypertensive drugs, anticoagulants, and antiplatelet agents.

8. Understand potential drug interactions and side effects associated with medications used in
the management of hemodynamic conditions.

9.Develop the skills necessary to make informed decisions regarding drug therapy for patients
with hemodynamic disorders.

THEME III: GENETICS

1. Understand the genetic factors contributing to oral health and diseases, including
conditions like oral cancer, cleft lip and palate, and inherited disorders.

2. Learn to assess the genetic risk factors for various oral pathologies and their implications
for patients' oral health.

3. Develop the skills to recognize genetic markers and mutations associated with oral
diseases through clinical and molecular diagnostic techniques.

4. Explore the fundamental molecular mechanisms of genetic disorders and their role in the
pathogenesis of diseases affecting different organ systems.

5. Learn to categorize genetic disorders based on their inheritance patterns, such as

autosomal dominant, autosomal recessive, X-linked, and mitochondrial inheritance.

6. Understand the clinical manifestations and complications of genetic diseases, including

their impact on various organ systems.

7. Gain insights into the field of pharmacogenetics, which involves understanding how
genetic variations can influence an individual's response to medications, including those
used in oral and general pathology.

8. Explore how genetic information is used in the development of personalized medicine

and targeted therapies for genetic conditions, including oral pathologies.

9. Consider the ethical and legal aspects of using genetic information in pharmacological
treatment decisions, patient consent, and confidentiality.
 WEEK-1
THEME-NEOPLASIA
PATHOLOGY

Hours Teache
S# Topics Learning Objectives Teaching Strategies Assessments r’s
name
Neoplasia Describe the definition of Interactive lecture BCQ, SEQ 1 Hour Dr. Aliya
neoplasia. Zaman
01
Describe the nomenclature of
neoplasia
Characteristic features To describe the Characteristic Interactive lecture BCQ, SEQ 1 Hour Dr. Aliya
of tumor of benign & Malignant tumour Zaman
02 To know Pathways of spread,
seeding, lymphatic and
haematogenous spread
Benign & Malignant Describe the gross and Interactive lecture BCQ, SEQ 2 Hour Dr. Aliya
Epithelial tumors microscopic features of benign Zaman
03
and malignant epithelial
tumours.
Benign & Malignant Describe the gross and Practical OSPE 2 Hour Dr. Aliya
connective tissue microscopic features of benign Zaman
04 tumors and malignant connective
tissue tumors.

ORAL PATHOLOGY

Classify white lesion of oral

mucosa according to their
Classification of white Lecture BCQ, SAQ, Dr.
01 etiology 1
lesions OSPE
Shahza
man

Epithelial dysplasia Lecture Dr.

Histological variations in oral
02 Histological slides BCQ, SAQ, OSPE 1 Seerat
mucosa
Describe hereditary white Dr. Faiz
lesions
Lecture
a) Oral epithelial
nevus
Hereditary
03 whiLeukoedemate BCQ, SAQ, OSPE 1
lesions b)

c) Follicular
keratosis

PHARMACOLOGY
1 Dr.
BCQs, SEQs,
01 Anti-neoplastic drugs Anticancer drugs-1 Lecture shujaull
OSPE
ah
1 Dr.
BCQS,
02 Anti-neoplastic drugs Anti-cancer drugs -2 Lecture shujaull
SEQS,OSPE
ah
4 Hours Dr.
Introduction to Introduction to
01 Practical OSPE shujaull
pharmacodynamics pharmacodynamics 1 & 2
ah
 BDS MODULE III
WEEK-2
THEME-NEOPLASIA
PATHOLOGY

Teaching Teacher’s
S# Topics Learning Objectives Teaching Strategies Assessments
h ours NSame
MOLECULAR BASIS Normal cell cycles and Interactive lecture BCQ, SEQ 1 Hour Dr. Shahrukh
OF CANCER -I fundamental principal Shaikh
of cancer regarding
cycle
Essential alterations in
01 malignant
transformation
teps of cell proliferation
Protooncogenes and
growth factors and
their receptors
MOLECULAR BASIS Two-hit hypothesis of Interactive lecture BCQ, SEQ 1 Hour Dr. Shahrukh
OF CANCER -II knudson Shaikh
Tumor supressor genes
Cellular changes in
tumor cells
02
DNA repair defects
Homing of tumor cells
Development of
sustained
angiogenesis
CARCINOGENIC To discuss Epidemiology Interactive lecture BCQ, SEQ 2 Hour Dr. Aliya
AGENTS of cancers
(Radiation To discuss Different
Zaman
Carcinogenesis) types of carcinogens
03
To discuss the
Mechanism of action of
radiation carcinogen

CARCINOGENIC To discuss the Interactive lecture BCQ, SEQ 2 Hour Dr. Aliya
AGENTS Mechanism of action of
Zaman
(Chemical &Viral chemical & viral
04
Carcinogenesis) carcinogen

ORAL PATHOLOGY
1. Describe 1 Dr.
reactive white Shahzaman
lesions

a) Frictiona
l
hyperker
atosis

b) Nicotine
01 Reactive white lesions stomatiti lecture BCQ.SAQ,OSPE
s

c) Hairy
leukopla
kia

d) Hairy
tongue

Preneoplastic and 1 Dr. seerat

Lecture
02 neoplastic white Leukoplakia BCQ.SAQ,OSPE
CBL
lesions I
Preneoplastic and 1 Dr. faiz
Oral submucous Lecture
03 neoplastic white BCQ.SAQ,OSPE
fibrosis CBL
lesions II

PHARMACOLOGY
BCQS SEQS 1 Dr. shujaullah
01 Autonomic drugs Introduction to ANS Lecture
OSPE
Cholinomimetic Direct BCQS SEQS 1 Dr. shujaullah
Autonomic Drugs Lecture
Acting OSPE
Cholinomimetic BCQS SEQS 1 Dr. shujaullah
Autonomic drugs Lecture
Indirect Acting OSPE
 WEEK-3
THEME- NEOPLASIA
PATHOLOGY
Teaching Teaching Teacher ‘s
S# Topics Learning Objectives Assessments
Strategies Hours name
Clinical features, Discuss grading and staging Interactive BCQ, SEQ 1 Hour Dr. Aliya
Grading and staging system of tumors lecture Zaman
01
of Neoplasia

Tumor Viruses Classify the tumor Viruses Interactive BCQ, SEQ 1 Hour Dr. Aliya
Describe the role of tumor lecture Zaman
viruses in malignant
02 transformation.
Discuss the mechanism
involved in carcinogenesis.

Diagnostic approach Describe various methods Practical OSPE 2 Hour Dr. Shahrukh
of Neoplasia for lab diagnosis of Shaikh
03 Neoplasia.

CBL Practical OSPE 2 Hour Dr. Shahrukh

Shaikh
04

ORAL PATHOLOGY
Lichen planus 1 Dr .
Preneoplastic and shahzamn
Lecture
01 neoplastic white BCQ.SAQ,OSPE
CBL
lesions III

Preneoplastic and Lupus erythematosus 1 Dr . faiz

Lecture
02 neoplastic white BCQ.SAQ,OSPE
CBL
lesions IV
CBL Lupus erythematosus Lecture BCQ.SAQ,OSPE 1 Dr. Fozia
03 CBL

PHARMACOLOGY
01 Autonomic drugs Anticholinergic drugs Lecture BCQS SEQS OSPE 1 Dr. shujaullah
02 Autonomic drugs Sympathomimetic Lecture BCQS SEQS OSPE 1 Dr. shujaullah
Effect of epinephrine on 2 Dr. shujaullah
01 Autonomic drugs practical OSPE
Rabbit eye
Effect of Pilocarpine on 2 Dr. shujaullah
02 Autonomic drugs practical OSPE
Rabbit eye
 WEEK-4
THEME-HAEMODYNAMICS
PATHOLOGY

Teaching Teacher’s name

S# Topics Learning Objectives Teaching Strategies Assessments Hours

Edema Interactive lecture BCQ, SEQ 1 Hour Dr. Alia Zaman

01
Hemorrhage, Interactive lecture BCQ, SEQ 1 Hour Dr. Alia Zaman
Hyperemia and
02
congestion

Thrombosis Practical OSPE 2 Hours Dr. Shahrukh shaikh

03
CBL Practical OSPE 2 Hours Dr. Shahrukh shaikh
04

ORAL PATHOLOGY

Discuss etiology, 1 Dr . Faiz

pathogenesis,
clinical features,
and histopathology
of
a) Congenit
al Lecture BCQS,SAQS,
01 Vascular Lesions
Hemangi CBL OSPE
oma

b) Lympha
ngioma

.Discuss etiology, 1 Dr . shahzaman

pathogenesis,
clinical features,
and histopathology
of the following
hyperplastic
lesions:
Hyperplastic Lecture BCQS, SAQs,
02 a) Epulides
lesions I CBL OSPE
b) Generali
zed
gingival
hyperpla
sia

c) Pyogenic 1 Dr . faiz
granulo
ma

d) Peripher
al giant
cell
granulo
Hyperplastic Lecture BCQs, SAQs,
03 ma
Lesions II CBL OSPE
e) Denture
Induced
Fibrous
Hyperpla
sia

PHARMACOLO
GY
BCQS SEQS 1 Dr. shujaullah
Autonomic drugs Alpha Lecture
OSPE
 blockers

Beta 1 Dr. shujaullah

BCQS SEQS
Autonomic drugs Blockers Lecture
OSPE

Effect of 2 Dr. shujaullah

Atropine
on
Autonomic drugs Practical OSPE
Rabbit
eye

Discussio 2 Dr. shujaullah

Autonomic drugs n Practical OSPE

WEEK-5
THEME- Hemodynamics

Pathology
Learning Teaching Hours Teacher
S# Topics Assessments ‘s name
Objectives Strategies
Embolism Interactive lecture BCQ, SEQ 1 Hour Dr. Aliya
01 Zaman

Infarction Interactive lecture BCQ, SEQ 1 Hour Dr.

02 Shahrukh
shaikh

Shock PRACTICAL OSPE 2 Hour Dr. Aliya

03 Zaman

CBL PRACTICAL OSPE 2 Hour Dr. Aliya

04 Zaman

ORAL PATHOLOGY

Explain the 1 Dr.

01 OSCC I etiology, Lecture BCQ.SAQ,OSPE shahzam
epidemiology an
Explain the 1 Dr .
pathogenesis of seerat
02 OSCC II Lecture BCQ.SAQ,OSPE
squamous cell
carcinoma
Explain the 1 Dr . faiz
histopathology of Lecture
03 OSCC III BCQ.SAQ,OSPE
squamous cell CBL
carcinoma

Pharmacology
1 Dr.
Drugs acting on Sedatives &
Lecture BCQS SEQS OSPE shujaulla
CNS Hypnotics
h
1 Dr.
Drugs Acting on Anti-Parkinson
Lecture BCQS SEQS OSPE shujaulla
CNS Drugs
h
2 Dr.
Drugs Acting on
Discussion Practical OSPE shujaulla
CNS
h
2 Dr.
Drugs Acting on
Discussion Practical OSPE shujaulla
CNS
h
 WEEK-6
THEME- GENETICS

Pathology
Teaching Teacher’
S# Topics Learning Objectives Teaching Strategies Assessments
hour s name
Classification of Classify genetic Interactive lecture BCQ, SEQ 1 Hour Dr. Aliya
Genetic Diseases & diseases. Zaman
01 Mutation
Define mutation and its
type

Mendelian Define mendelian Interactive lecture BCQ, SEQ 1 Hour Dr.

disorders disorders. Shahrukh
02 Shaikh
Classify mendelian
disorders

Chromosomal Classify chromosomal Interactive lecture BCQ, SEQ 1 Hour Dr. Aliya
disorders disorders. Zaman

Describe types of
03
structural and
numerical
abnormalities

Diagnosis of Discuss various method PRACTICAL OSPE 02 Hour Dr.

Genetic diseases for the diagnosis of Shahrukh
04
genetic diseases. Shaikh

Oral Pathology

Describe staging and BCQ 1

01 OSCC IV grading of squamous Interactive Lecture SAQs
cell carcinoma. OSPE
Explain the etiology, 1
pathogenesis, clinical BCQ
Basal Cell
02 features, and Lecture SAQs
Carcinoma
histopathology of Basal OSPE
Cell Carcinoma.
Describe the etiology, 1
pathogenesis and
diagnostic features of
the following verruca
papillary lesions

a) Squmao
us cell
papillom BCQ
Verruca Papillary
03 a Interactive Lecture SAQs
lesions I
OSPE
b) Papillary
hyperpla
sia

c) hyperpla
sia

Pharmacology

1 Dr.
Drugs Acting on General Ansthetics-1 shujaullah
Lecture BCQS SEQS OSPE
CNS

1 Dr.
General Ansthetics-2 shujaullah
Drugs acting on CNS Lecture BCQS SEQS OSPE

Effect of lidocaine on 2 Dr.

Drugs acting on CNS rabbit eye -1 Practical OSPE shujaullah

Effect of lidocaine on 2 Dr.

Drugs acting on CNS rabbit eye -2 Practical OSPE shujaullah
 WEEK-7
THEME- GENETICS
Pathology
Learning Teaching Teaching Teacher’s
S# Topics Assessments hours name
Objectives Strategies
Inborn errors of Interactive lecture BCQ, SEQ 1 Hour Dr.Aliya
Metabolic Zaman
01
disorders

Nutritional Interactive lecture BCQ, SEQ 1 Hour Dr.Aliya

02 deficiency Zaman

Serological Differentiate Practical OSPE 2 Hour Dr.

testing among various Shahrukh
serological Shaikh
03
tests: Typhi
dot; ELISA; ICT
e.g Malaria
Practical OSPE 2 Hour Dr.
04 CBL Shahrukh
Shaikh

ORAL PATHOLOGY
Describe the 1 Dr faiz
etiology,
pathogenesis
and diagnostic
features of the
following
verruca
papillary
lesions

a) Co
nd
yl
o
ma
lat
u
m
Verruca
01 Papillary lesions b) Co Interactive lecture BCQ,SAQ,OSPE
II
nd
yl
o
ma
ac
u
mi
nat
u
m

c) Fo
cal
epi
the
lia
l
hy
 pe
rpl
asi
a

02 CBL I Leukoplakia CBL OSPE 1 Dr.Faiz

03 CBL II LichenPlanus CBL OSPE 1 Dr. Seerat
PHARMACOLOGY
Drugs Acting on Local 1 Dr.
O1 Lecture BCQs, SEQs, OSPE shujaullah
CNS Anesthetics
Drugs Acting on Anti- 1 Dr.
O2 Lecture BCQS SEQS OSPE shujaullah
CNS Depressants
Drugs Acting on 2 Dr.
O3 Revision practical OSPE shujaullah
CNS
Drugs Acting on 2 Dr.
O4 Revision practical OSPE shujaullah
CNS

WEEK-8
THEME-

Pathology
Learning Teaching Teacher ‘s name
S# Topics Assessments
Objectives Strategies
01
02

ORAL PATHOLOGY
CBL III OSF Cbl OSPE 1 Dr. Shahzaman
CBL IV OSCC Cbl OSPE 1 Dr. Seerat
CBL V • Squa 1 Dr. Faiz
mous
cell
papill
oma
• Hema
ngiom
Cbl OSPE
a
• Dentu
re
induc
edhyp
erplas
ia
\ PHARMACOLOGY
Drugs Dr. shujaullah
Anti BCQS SEQS
Acting on Lecture 1
Psychotics OSPE
CNS
Drugs Dr. shujaullah
BCQS SEQS
Acting on Alcohol Lecture 1
OSPE
CNS