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Revision date: 01/02/2021 Shared
KCP Formulated
Substance of concern CAS Number Issue Summary
Personal Care

Products must not

contain a concentration
of 1,4-Dioxane greater
1,4- Dioxane 123-91-1 Carcinogenicity;
than 10 ppm in
formulated personal
care products

Residual
monomers after
Acrylates (monomer) Follow Cosmetic Limits
copolymer
formation

Must meet Global BSE

requirements. Notified
on K-C Disclosure form
Animal Derived Ingredients
and Animal derived
statement/certificate of
BSE conformance

Skin sensitisation
Benzisothiazolinone 2634-33-5 Non-Use

Reprotoxicity;
Benzophenone 119-61-9 endocrine Non-Use
disruption
Bisphenol A (4,4'-
80-05-7 Endocrine Disruption Non-Use
Isopropylidenediphenol)
10043-35-3 ; 11113-50-1 Reproductive
Boric Acid/Borates Toxicity/ Non-Use
Carcinogenicity
Butylated Hydroxylanisole
25013-16-5 Endocrine Disruption Non-Use
(BHA)
Butylated hydroxytoluene
128-37-0 Carcinogenicity Non-Use
(BHT)
Butylparaben 94-26-8 Endocrine Disruption Non-Use
Cocamide DEA 68603-42-9 Carcinogenicity Non-Use
8050-09-7 Skin sensitisation
Colophony Resins 8052-10-6 Non-Use
73138-82-6
Carcinogenicity;
Cyclopentasiloxane (D5) 541-02-6 toxicity to the Non-Use
environment
 CMR 3
Cyclotetrasiloxane (D4) (AKA (Reproductive Non-Use
293-51-6, 556-67-2
octamethylcyclotetrasiloxane) toxicity);
Carcinogenicity
Non-Use
Diethanolamine ( MEA, TEA) 111-42-2 Carcinogenicity;

Carcinogenicity,
1746-01-6 Reproductive/Dev
elopmental
Dioxins toxicity, immune
2,3,7,8- tetrachlorodibenzo system effects, Non-Use
para dioxin (TCDD) endocrine
disruption & POP

131-53-3 Reprotoxicity;
Dioxybenzone (Benzophenone-
endocrine Non-Use
8)
disruption
Ethyl paraben 120-47-8 Endocrine Disruption Non-Use
Formaldehyde 50-00-0 Carcinogenicity Non-Use
Formaldehyde
Bronopol (2-Bromo-2- Donating
52-51-7 Non-Use
Nitropropane-1,3-Diol) Preservative (PR)

Formaldehyde
78491-02-8
Donating
Diazolidinyl urea Non-Use
Preservative (PR)

Formaldehyde
6440-58-0 Donating
Non-Use
DMDM Hydantoin Preservative (PR)

Formaldehyde
Donating
Imidazolidinyl urea 39236-46-9 Non-Use
Preservative (PR)

Formaldehyde
100-97-0 Donating
Non-Use
Methenamine Preservative (PR)

Formaldehyde
Donating
Sodium 70161-44-3 Non-Use
Preservative (PR)
hydroxymethylglycinate

Heavy Metals (Lead,
Cadmium, Mercury, Nickel,
Arsenic)
Mercury (7439-97-6), Nickel
(7440-02-0); Arsenic (7440-38-
2); Cadmium (7440-43-9); Endocrine Non-Use. Ensure
Beryllium (7440-41-7); Disruption;carcino compliance with
Molybdenum (7439-98-7); gen regulatory limits.
Antimony (7440-36-0); Cobalt
(7440-48-4)

Iodopropynyl butylcarbamate
Allergen,
(IPBC); 3-iodo-2-propynyl- 55406-53-6 Non-Use
immunotoxicity
butylcarbamate

Endocrine
Isobutylparaben 4247-02-3 Non-Use
Disruption
Isocyanates Sensitisation &
Toluene Diisocyanate (TDI) 26471-62-5 irritation
Non-Use. Regulatory
2,4-Toluene diisocyanate 91-08-7
and Safety assessment if
2,6-Toluene diisocyanate 584-84-9
residual.
Diphenylmethane diisocyanate 26447-40-5
(MDI)
Endocrine
Isopropyl paraben 4191-73-5 Non-Use
Disruption
Sensitisation &
Methylchloroisothiazolinone/ 26172-55-4 /
irritation Non-use
Methylisothiazolinone 2682-20-4

Methyldibromo Glutaronitrile 35691-65-7 Allergen Non-Use

Sensitisation &
Methylisothiazolinone 2682-20-4 Non-Use
irritation
Methylparaben 99-76-3 Endocrine Disruption Non-Use

Not
biodegradeable,
Microplastics/Microbeads Non-use
bioaccumulative.
Nanomaterials/Nanoparticles:
Including, but not limited to:
Titanium Dioxide (13463-67-7)
Zinc Oxide (1314-13-2)
Silica (112945-52-5, 60676-86-
0, 7631-86-9)
Acrylates
Talc (14807-96-6)
Carbon Black (1333-86-4,
7440-44-0)
Silver (7440-22-4)
Nanomaterials/Nanoparticles:
Including, but not limited to:
Titanium Dioxide (13463-67-7)
Zinc Oxide (1314-13-2)
Silica (112945-52-5, 60676-86-
0, 7631-86-9)
Non-Use
Acrylates
Talc (14807-96-6)
Carbon Black (1333-86-4,
7440-44-0)
Silver (7440-22-4)

Natural Rubber Latex 9006-04-6 Sensitisation Non-Use

62-75-9 ; 86-30-6 Endocrine
Disruption;carcino
Safety and Regulatory
gen
Assessment Required:
Nitrosamines: N- nitrosamines must not
Nitrosodimethylamine form part of the
(NDMA), also known as composition of cosmetic
dimethylnitrosamine (DMN); products above trace
N-Nitrosodimethylamine levels that are
(NDMA) technically unavoidable
in Good Manufacturing
Practices.

84852-15-3, 25154-52-3, Endocrine

Nonylphenol and Nonylphenol
104-40-5, 9016-45-9, Disruption
ethoxylates (also known as Non-Use
127087-87-0
Alkyl Phenol Ethoxylates)

Organotin compounds CMR, Endocrine

Monobutyltin (MBT) disruption & PBT
Dibutyltin (DBT)
Non-Use
Tributyltin (TBT)
Triphenyltin (TPT)
Dioctyltin (DOT) etc.
Endocrine
Oxybenzone
131-57-7 Disruption;carcino Non-Use
(Benzophenone-3)
gen

Palm oil and Palm derivatives Multiple Sustainable sourcing Non-Use

 Safe as used
when formulated
to be non-
Polyethylene Glycol (PEG)
Multiple irritating. PEG Non-Use
Derivatives
compounds have
Public Relations
risk in EU

335-67-1 SVHC - Toxic for

Pentadecafluorooctanoic acid
reproduction & Non-Use
(PFOA)
PBT
1763-23-1 GHS
Carc. 2
Carcinogen,
category 2
Repr. 1B Toxic to
reproduction,
category 1B
Perfluorooctane sulfonate STOT RE 1 Specific
Non-Use
(PFOS) target organ
systemic toxicity
following
repeated
exposure,
category 1

Perlide (HHCB)
(galaxolide)(1,3,4,6,7,8- Polycyclic musk - Non-Use the chemical
hexahydro-4,6,6,7,8,8- 1222-05-5 PR some used in or the fragrance
hexamethyl-cyclopenta(g)-2- Fragrances containing it
benzopyra)
PHMB (Polyaminopropyl 27083-27-8, 32289-58-0,
EU CMR Non-Use
biguanide) 133029-32-0
Phthalates: All esters of o-
phthalic acid, including but not
limited to:
Di-isononyl phthalate (DINP)
(28553-12-0)
Di(ethylhexyl) phthalate
(DEHP) (117-81-7)
Di-n-octyl phthalate (DNOP)
(117-84-0)
Di-iso-decyl phthalate (DIDP)
(26761-40-0)
Butyl benzyl phthalate (BBP)
(85-68-7)
Dibutyl phthalate (DBP) (84-74-
2)
Di-isobutyl phthalate (DiBP)
(84-69-5)
Dicyclohexyl phthatate (DCHP)
(84-61-7)
Diisooctyl phthalate (27554-
26-3)
1,2-Benzenedicarboxylic acid,
di-C7-11-branched and linear
alkyl
esters (DHNUP) (68515-42-4)
1,2-Benzenedicarboxylic acid,
di-C6-8-branched alkyl esters,
C7-
Propylparaben
Quaternium-15
Di-isononyl phthalate (DINP)
(28553-12-0)
Di(ethylhexyl) phthalate
(DEHP) (117-81-7)
Di-n-octyl phthalate (DNOP)
(117-84-0)
Di-iso-decyl phthalate (DIDP)
(26761-40-0)
Butyl benzyl phthalate (BBP)
(85-68-7)
Dibutyl phthalate (DBP) (84-74-
2)
Di-isobutyl phthalate (DiBP)
(84-69-5)
Endocrine Disruption Non-Use
Dicyclohexyl phthatate (DCHP)
(84-61-7)
Diisooctyl phthalate (27554-
26-3)
1,2-Benzenedicarboxylic acid,
di-C7-11-branched and linear
alkyl
esters (DHNUP) (68515-42-4)
1,2-Benzenedicarboxylic acid,
di-C6-8-branched alkyl esters,
C7-
rich (DIHP) (71888-89-6)
1,2-Benzenedicarboxylic acid,
dihexyl ester, branched and
94-13-3 Endocrine Disruption Non-Use
Formaldehyde
Donating
4080-31-3, 51229-78-8 Non-Use
Preservative (PR)

Reprotoxicity;
Suliisobenzone
4065-45-6 endocrine Non-Use
(benzophenone-4)
disruption
14807-96-6 Carcinogenicity Non-Use as an
Talc intentionally added
ingredient
68647-73-4 Irritation/sensitiza
Tea Tree Oil Non-Use
tion
Triclocarban ‎101-20-2 Env. Toxicity Non-Use
Environmental
Toxicity,
Triclosan 3380-34-5 Non-Use
effectiveness,
reproductive
 26523-78-4 Sensitisation &
Tris (nonylphenyl) phosphite
endocrine Non-Use
(TNPP)
disruption