INDEX NUMBER

ACCRA TECHNICAL UNIVERSITY

FACULTY OF APPLIED SCIENCES
DEPARTMENT OF MEDICAL LABORATORY SCIENCES
END OF SECOND SEMESTER FULL-TIME EXAMINATION, 2019/2020 ACADEMIC YEAR
COURSE CODE: MLB 108 COURSE TITLE: BIOPHYSICS
DATE:12/09/2020
INSTRUCTIONS: Attempt all questions for 60 marks
Write only answers ( be brief and concise) in the answer booklet; copying of questions into
answer booklet will incur a penalty.

Q1.
(i) Define Surface tension of a liquid in Biological membrane
(ii) Explain briefly the existence of surface tension at the boundary of biological fluids.
(iii) State one direct and one indirect method of measuring surface tension.
[10marks]

Q2.
15 by Diffusion as applied in biological membrane.
(i) What is meant
(ii) State three factors that affect diffusion.
(iii) Write down mathematical expression of diffusion from Fick’s law.
[10marks]

Q3. According to Hagen-Poisseuill’s law the flow of fluid in Biological membrane is given by the
expression.

𝜋𝑟 4 ∆𝑃
V=
8𝑛∆𝑙
(i) Define each of the terms in the equation above
 (ii) State two methods of measuring viscosity of fluid.
(iii) State one practical application of viscosity in medical practice.
[10marks]

Q4.
(a) State the following laws as applied to Biological fluid in membrane.
(i) Vant’ Hoff’s law
(ii) Nernst law equation
(iii) Stok’s law
(b)
(i) State the significant of each law in (a) above in biological fluid flow.
(ii) Explain briefly why fluid in biological membrane must be in a state of buffer.
[10marks]
Q 5. Define the following as applied to electrical activity of cells
(i) Action Potential
(ii) Membrane Potential
(iii) Bioelectrogenesis .
[10marks]

15
Q6. The Goldman’s theory is expressed by the equation below;

(i) Define each of the terms in the equation above

(ii) State one application of the equation above.
[10marks]