Commonly Used Otic Medications in Small

Animal General Practice

Otic medications are commonly used therapeutics in veterinary medicine. Working knowledge of the medications available is important to know in preparation for small animal general
practice.

In regard to the NAVLE®, a general knowledge of these factors is necessary, which is the goal of the PowerPage. However, this should be used only as a guide to refresh your memory.
Please refer to a drug formulary for a more detailed review and complete prescribing information.

Generic
General Name or Drug Class or
Category Brand Name Ingredients Use Route(s) Common Indications Special Considerations

Synotic Otic Fluocinolone, Corticosteroid Topically Used for acute or chronic Use at lowest effective dose
Anti- Solution DMSO applied to allergic otitis
inflammatory ears ● Reduces
Agents inflammation and
hyperplasia / edema
● Decreases related
clinical signs
(discomfort,
pruritus, etc.)
● Reduces sebaceous
and apocrine gland
secretions

Antibacterial Baytril Otic Enrofloxacin, Quinolone Topically Commonly used to treat Performing culture and
Agents Silver antibiotic applied to bacterial otitis caused by sensitivity testing is
Sulfadiazine ears Pseudomonas spp. recommended to guide
bacterial otitis treatment
plan

Combination Posatex Posaconazole/ Combination Topically Used in canine otitis externa Do not use if tympanic
Antibacterial + Orbifloxacin/ of antifungal/ applied to cases consisting of susceptible membranes are not intact
Mometasone
Corticosteroid antibiotic/ ears strains of:
+ glucocorticoid ● Malassezia
Antifungal agent pachydermatis
Agents ● Coagulase positive
Staphylococci spp.,
Pseudomonas
aeruginosa and
Enterococcus faecalis

Mometamax Gentamicin/ Combination Topically Used in canine otitis externa Gentamicin is known to be
Mometasone/ of antibiotic/ applied to cases consisting of susceptible ototoxic. Use with caution.
Clotrimazole
glucocorticoid ears strains of: Do not use if tympanic
/antifungal ● Malassezia membranes are not intact
agent pachydermatis
● Coagulase positive
Staphylococci spp,
Pseudomonas spp,
Proteus mirabilis and
beta-hemolytic
Streptococci,
Enterococcus faecalis

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 Commonly Used Otic Medications in Small
Animal General Practice

General Generic Name or Drug Class or

Category Brand Name Ingredients Use Route(s) Common Indications Special Considerations

Surolan Otic Miconazole Combination of Topically Used in canine otitis Avoid if tympanic
Suspension nitrate/ Polymyxin Antifungal/ applied to externa cases consisting of membranes are not intact
Antibiotic/
B sulfate/ ears susceptible strains of:
Glucocorticoid
Prednisolone ● Malassezia
Agent
acetate pachydermatis
● Staphylococcus
pseudintermedius

Tresaderm Neomycin/ Considered a Topically Used in bacterial, mycotic Store in refrigerator

Dexamethasone/ dermatologic applied and inflammatory skin
Thiabendazole solution conditions and in canine Clinical Tip: Some patients
and feline otitis externa may be sensitive to
cases neomycin - avoid use in
these patients

Other Gentaved Gentaved These medications are not

Combination as commonly used but
Antibacterial + may be available in some
Corticosteroid small animal general
+ practices. Make sure to
Antifungal read product insert label
Medications before use.

Animax, Nystatin/
DermaVet, Neomycin
Dermalog, sulfate/
Quadritop, Thiostrepton/
Panalog Triamcinolone
acetonide

Otomax, Tri-Otic Clotrimazole/

Gentamicin/
Betamethasone

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 Commonly Used Otic Medications in Small
Animal General Practice

General Generic Name Drug Class or

Category Brand Name or Ingredients Use Route(s) Common Indications Special Considerations

Long - acting Claro Florfenicol/ Combination Topically Used in canine otitis externa Check that tympanic
ear Terbinafine/ Antibiotic/ applied to ears cases consisting of membrane is intact
medications Mometasone Antifungal/ susceptible strains of: prior to administration
Anti- Note: Single ● Malassezia
Inflammatory use treatment pachydermatis Ensure ears have been
Otic Medication regimen ● Staphylococci thoroughly cleaned
pseudintermedius and dried prior to
administration

Treatment effect is up
to 30 days

Osurnia Florfenicol/ Combination Topically Used in canine otitis externa Check that tympanic
Terbinafine/ Antibiotic/ applied to ears cases consisting of membrane is intact
Betamethasone
Antifungal/ susceptible strains of: prior to administration
Anti- Note: applied in ● Malassezia
inflammatory clinic after ears pachydermatis Store in fridge, bring to
Otic Medication are cleaned and ● Staphylococcus room temperature
dried. Requires pseudintermedius prior to administration
2nd application
1 week after the Ensure that owners do
initial dose. not clean ears for 45
days after initial dose

References:
● Baytril Otic. Bayer. Retrieved from https://www.bayerdvm.com/products/baytril-otic-enrofloxacin-silver-sulfadiazine-emulsion/
● Claro. Bayer DVM. Retrieved from https://www.bayerdvm.com/products/claro-florfenicol-terbinafine-mometasone-furoate-otic-solution/
● Cote, Etienne. Clinical Veterinary Advisor: Dogs and Cats. 3rd edition.
● Mometamax. Merck Animal Health. Retrieved from https://www.merck-animal-health-usa.com/product/canine/Mometamax-Otic-Suspension/1
● Plumb, D.C. Plumb’s Veterinary Drug Handbook, 7th edition.
● Posatex. Merck Animal Health. Retrieved from https://www.merck-animal-health-usa.com/product/canine/Posatex-Otic-Suspension/1
● Surolan. Elanco Animal Health. Retrieved from https://www.elanco.us/products-services/dogs/surolan
● Osurnia. Elanco Animal Health. Retrieved from https://www.elanco.us/products-services/dogs/osurnia
● Tresaderm. Merial Animal Health. Retrieved from http://resources.vet-advantage.com/media/attachments/2016/10/03/Tresaderm_Promo.pdf
● Pharmacy Formulary, University of Florida.
● Veterinary Pharmacology, University of Florida

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