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CARBOHYDRATE
MODULE 2. TOTAL PARENTERAL • Dextrose provides the carbohydrate content of
NUTRITON PN, up to 75% of the total energy of the
Topic Outline solution. It provides 3.4 kcal/g.
1. Total Parenteral Nutrition • Glucose is the body’s main source of energy.
a. Indications • Concentration is 12.5% (maximum for
b. Composition peripheral introduction) to 25% (total
c. Ordering and Mixing PN Solutions parenteral nutrition)
d. Equipment • Restricted in ventilator patients because
e. Initial Considerations oxidation of glucose produces more carbon
f. General PN Initial Procedures dioxide than does oxidation of fat.
g. Types of Parenteral Nutrition
h. Choice of Nutrition Regimen PROTEIN
i. PN Infusion Rate • Mixture of essential and non-essential amino
j. Monitoring of Nutrition Support acids
k. TPN Procedures • Concentration 3.5 – 15%
• Quantity of amino acids depends on patients
TOTAL PARENTERAL NUTRITION estimated requirements and hepatic and renal
• It is a way of supplying all the function.
nutritional needs directly into
blood stream bypassing FAT
gastrointestinal tract. • Lipid emulsion is a soluble form of fat that
• It is administered outside the allows it to be infused safely into the blood.
digestive tract, intravenously. • Safflower and soybean oil with egg lecithin
used as an emulsifier.
INDICATIONS • Isotonic
1. When individuals cannot or should not get • Significant source of calories.
nutrition through eating. • Usual dose is 0.5 to 1 g/kg/day to supply 20-
2. When the intestines are obstructed, when the 30% of total kcal requirement.
small intestine is not absorbing nutrients • IV fat contraindicated for severe hepatic
properly or a gastrointestinal fistula (abnormal pathology, hyperlipidemia or severe egg
connection) is present. allergies.
3. When the bowels need to rest and not have any
• Used cautiously with atherosclerosis, blood
food passing through them. Bowel rest may be
coagulation disorders.
necessary in Crohn’s disease, pancreatitis,
ulcerative colitis, and with prolonged bouts of
MICRONUTRIENTS
diarrhea in young children.
• Standard multi-vitamin and trace mineral
4. Individuals with severe burns, multiple
preparations added to parenteral solutions to
fractures, and in malnourished individuals to
meet micronutrient needs.
prepare them for major surgery, chemotherapy,
or radiation treatment.
ELECTROLYTE
5. Individuals with aids or widespread infection
(sepsis). • It is dictated by patient’s blood chemistry
values and physical assessment findings.
COMPOSITION OF INGREDIENTS IN BAG
FOR IV DELIVERY ORDERING AND MIXING PN SOLUTIONS
• Usual fluid volume is 1.5 - 2.5L over a 24 hours • The physician writes the order for the TPN
period for most people. prescription.
• Actual infusion depends on: • The pharmacist mixes the TPN solution using
1. Site of infusion aseptic technique.
2. Patient’s fluid and nutrient requirements. • Prescriptions are compounded by mixing the
solutions at a 1:1 dextrose-to-amino acid ratio
and placing in 1-L bags.
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INTRAVENOUS ACCESS FOR PN INTRA-DIALYTIC
• Intravenous lines for PN may be inserted into a INTRA-DIALYTIC- administered during
number of different veins although the tip hemodialysis
(inner end) of the line will usually be located in Access:
the: 1. Vena cava; or 2. Axillary veins; or 3. • Venous port of hemodialysis tubing (into
Subclavian veins. AV shunts
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FAR EASTERN UNIVERSITY
INSTITUTE OF HEALTH SCIENCES AND NURSING
DEPARTMENT OF NURSING
INSERTION SITES
INTERNAL JUGULAR VEIN
• This site is chosen frequently as there is a high
rate of successful insertion and a low incidence
of complications such as pneumothorax
• Internal jugular veins are short, straight and
relatively large allowing easy access, however,
catheter occlusion may occur as a result of head
movement and may cause irritation in conscious
patients.
SUBCLAVIAN VEIN
• It is acquired by threading a central venous • This site is often chosen as there are more
catheter into any of several large veins. ❑It is recognizable anatomical landmarks, making
threaded so that the tip of the catheter rests in insertion of the device easier.
the lower third of the superior vena cava. • Because this site is positioned beneath the
clavicle there is a risk of pneumothorax during
CVP CATHETER insertion.
It is an important treatment tool used to: • A subclavian CVC is generally recommended
1. Assess right ventricular function and systemic as it is more comfortable for the patient.
fluid status.
2. Allow for rapid infusion. FEMORAL VEIN
3. Allow for infusion of hypertonic solutions and • This site provides rapid central access during an
medications that could damage veins. emergency such as a cardiac arrest.
4. Allow for serial venous blood assessment • As the CVC is placed in a vein near the groin
there is an increased risk of associated infection.
FACTORS THAT AFFECT CVP • In addition, femoral CVCs are reported to be
• Normal CVP is 2 – 6 mm hg. uncomfortable and may discourage the
• The condition of the patient and the treatment conscious patient from moving.
being administered determine how often CVP
measurement should take place. CVP RECORDING
• CVP is elevated by: • It is usually recorded at the mid-axillary line
1. Overhydration which increases venous where the manometer arm or transducer is level
return with the phlebotomid axis.
2. Heart failure or PA stenosis which limit • This is where the fourth intercostal space and
venous outflow and lead to venous midaxillary line cross each other allowing the
congestion measurement to be as close to the right atrium
3. Positive pressure breathing, straining. as possible.
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8. When ‘zeroed’ is displayed on the monitor,
USING A MANOMETER replace the cap on the three-way tap and turn
1. Explain the procedure to the patient to gain the tap on to the patient.
informed consent. 9. Observe the CVP trace on the monitor. The
2. If IV fluid is not running, ensure that the CVC waveform undulates as the right atrium
is patent by flushing the catheter. contracts and relaxes, emptying and filling with
3. Place the patient flat in a supine position if blood.
possible. Alternatively, measurements can be 10. Document the measurement and report any
taken with the patient in a semi-recumbent changes or abnormalities.
position. The position should remain the same
for each measurement taken to ensure an INTERPRETING MEASUREMENTS
accurate comparable result. 1. The normal range for CVP is 5-10cm H2O (2-
4. Line up the manometer arm with the 6mmHg) when taken from the mid-axillary line
phlebostatic axis ensuring that the bubble is at the fourth intercostal space.
between the two lines of the spirit level. 2. Many factors can affect CVP, including vessel
5. Move the manometer scale up and down to tone, medications, heart disease and medical
allow the bubble to be aligned with zero on the treatments.
scale. This is referred to as ‘zeroing the 3. A CVP measurement should be viewed in
manometer ‘. conjunction with other observations such as
6. Turn the three-way tap off to the patient and pulse, blood pressure and respiratory rate and
open to the manometer. the patients response to treatment.
7. Open the IV fluid bag and slowly fill the
manometer to a level higher than the expected POTENTIAL COMPLICATIONS
CVP 1. Hemorrhage from the catheter site
8. Turn off the flow from the fluid bag and open 2. Catheter occlusion
the three-way tap from the manometer to the 3. Infection
patient. 4. Air embolus
9. The fluid level inside the manometer should fall 5. Catheter displacement
until gravity equals the pressure in the central
veins.
10. When the fluid stops falling the CVP
measurement can be read. If the fluid moves
with the patient’s breathing, read the
measurement from the lower number.
11. Turn the tap off to the manometer.
12. Document the measurement and report any
changes or abnormalities.
USING A TRANSDUCER
1. Explain the procedure to the patient to gain
informed consent.
2. The CVC will be attached to intravenous fluid
within a pressure bag. Ensure that the pressure
bag is inflated up to 300mmHg.
3. Place the patient flat in a supine position if
possible. Alternatively, measurements can be
taken with the patient in a semi-recumbent
position. The position should remain the same
for each measurement taken to ensure an
accurate comparable result.
4. Catheters differ between manufacturers;
however, the white or proximal lumen is
suitable for measuring CVP.
5. Tape the transducer to the phlebostatic axis or
as near to the right atrium as possible.
6. Turn the tap off to the patient and open to the
air by removing the cap from the three-way port
opening the system to the atmosphere.
7. Press the zero button on the monitor and wait
while calibration occurs.
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FAR EASTERN UNIVERSITY
INSTITUTE OF HEALTH SCIENCES AND NURSING
DEPARTMENT OF NURSING
MODULE 4 CARE OF CLIENTS WITH brain damaged, or patients with spinal cord
MECHANICAL VENTILATOR injuries
Topic Outline
1. Care of Clients with Mechanical Ventilator INDICATION FOR MECHANICAL
a. Purposes of Mechanical Ventilator VENTILATOR USE
b. Indications 1. Continuous decrease in oxygenation
c. Complications of long-term 2. Increase arterial carbon dioxide
ventilation 3. Persistent acidosis
d. Troubleshooting Ventilator Alarms 4. Respiratory failure:
e. What are the bundles of care to avoid a. Apnea / respiratory arrest
Ventilator-associated Pneumonia b. Inadequate ventilation(acute vs
(VAP)? chronic)
f. Closed system suctioning c. Inadequate oxygenation
g. Plan of Care for Ventilated Patients d. Chronic respiratory insufficiency with
FTT
CARE FOR PATIENT WITH MECHANICAL e. Compromised airway patency
VENTILATOR 5. Cardiac insufficiency
a. Eliminate the work of breathing
b. To reduce the oxygen consumption
6. Neurologic dysfunction
a. Central hypoventilation and frequent
apnea
b. Comatose patient with GCS < 8
c. Inability to protect the airway
7. ABG Results
8. If the patient is under the following conditions:
Patients who can’t breathe, for any reason, need to.be a. Multiple trauma
attached on a mechanical ventilator. This machine helps b. Shock
critically ill patients achieve the needed oxygen to c. Multi-organ failure
survive. The patient is then connected to the ventilator d. Drug overdose
with a tube that passes into the mouth and down to the e. Thoracic or abdominal surgery
trachea. There is some point of complexity on this type f. Neuromuscular disorders
of procedure that is why Nurses who are assigned in the g. Inhalation injury
intensive or critical unit should be competent in caring h. COPD
for the patient with mechanical ventilator.
COMPLICATIONS OF LONG-TERM
PURPOSES OF MECHANICAL VENTILATION VENTILATION
• The patient does not have to work as hard to Infections– A foreign object such as the endotracheal
breathe– their respiratory muscles rest tube in the trachea makes the patient more susceptible
• Helps the patient get adequate oxygen and to bacteria entering the lungs. This is treated with the
clears carbon dioxide use of antibiotics.
• Preserves a stable airway and preventing injury
from aspiration Pneumothorax –This is the condition when the lung/s
• Air is delivered in patients with compromised collapses. It is a complication when the lungs are
ventilation damaged because of gets over-expansion. If this
• Oxygenate the different organs of the body happened, a chest tube is inserted on the collapsed lung
• Expel the carbon dioxide in the lungs to allow it to re-expand and seal the leak.
• Provide comfortable breathing pattern to
patients experiencing shortness of breath Lung damage – The air forced in the lungs can increase
• To breathe for patients who are seriously the risk for injury.
compromised ventilation such as in comatose,
Side Effects of medications– Intubated patients are
most of the time given sedatives to allow easier
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ventilation of the machine. These medications keep the So as a nurse, how will you manage if there’s an alarm?
patient calm and sleepy. First, assess the patient if he/she is in distress. Identify
the alarm whether high pressure or low pressure. Some
Maintenance of Life– The ventilator sometimes serves mechanical ventilators have their own indicators and
as the only reason why the patient is alive. Organs fail shows the cause of the alarm, so it’s important to check
because the body is dying, this includes the lungs. your machine as well.
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• Avoid pressure ulcers. Turn patient to sides 14. Upon completion of suctioning, withdraw
every 2 hours or as needed. Apply cream or catheter, ensuring that tip is completely
ointment to bony prominences or as indicated withdrawn from airway.
by the physician. 15. Rinse suction catheter after each suctioning by
• Elevate head of bed >30 degrees. Always depressing thumb control and squeezing a new
observe aspiration precaution. saline irrigation using the 10cc syringe or
• Assess patient daily for extubation readiness. depending on the set-up of your close suction
Early extubation can greatly prevent VAP. kit.
• Daily interruption of sedation. 16. Repeat suctioning process until the patient’s
airway is clear.
CLOSED SYSTEM SUCTIONING 17. Discard personal protective equipment and
EQUIPMENT wash hands.
• Sterile Closed Suction Kit 18. Evaluate patient’s condition by auscultating the
• Normal Saline Irrigation lung fields and by monitoring patient’s
• Suctioning machine or device: wall or portable oxygenation using pulse oximeter.
• Oxygen source
PLAN OF CARE FOR VENTILATED PATIENTS
• Personal protective equipment
• Promote effective breathing pattern
• 10 cc syringe
• Promoted adequate gas exchange
• Pulse oximeter
• Improve the nutritional status that the body
• Stethoscope needs
• Prevent patient from developing pulmonary
PROCEDURE
infection.
1. Check the guidelines or standard procedure of
your unit for closed-suctioning system. • Prevent patient from developing problems
related to immobility.
2. Prepare all needed equipment. Position all
supplies so that they are easily accessible. • Patient and/or family will demonstrate
Check suction setup for correct functioning. understanding of the purpose for mechanical
Read instructions of the closed-suction kit. ventilation
3. Explain the procedure to the client. Explain the
benefits of closed-suctioning system and how it References
can prevent infection. Hinkle, J.L. & Cheever, K.H. (2018). Brunner &
4. Assess patient first. Auscultate patient’s lung Suddarth's Textbook of Medical-Surgical
fields for abnormal breath sounds. Attach Nursing (14th ed.). Philadelphia: Wolters
patient to continuous pulse oximeter Kluwer.
monitoring device.
5. Wear personal protective equipment. Perform Ignatavicius, D.D., Workman, M.L., & Rebar, C.R.
hand hygiene (2018). Medical-Surgical Nursing: Concepts for
6. Attach closed suction catheter system between Interprofessional Collaborative Care (9th ed.).
ventilator circuit and patient airway. St. Louis: Elsevier.
7. Ensure that wall or portable suction is turned on
(no higher than 120 mmHg). Set vacuum setting Lewis, S.L., Dirksen, S.R., Heitkemper, M.M., Bucher,
according to policy of your unit. L., & Harding, M.M. (2017). Medical-Surgical
8. Attach suction tubing from setup to suction port Nursing: Assessment and Management of
of catheter. Clinical Problems (10th ed.). St. Louis: Elsevier.
9. Hyper-oxygenate patient to 100% 02 for 2 – 5
minutes.
10. Attach saline to irrigation port. You may use
also a 10 cc syringe for introducing saline
irrigation or depending upon the set-up of your
closed-suction kit.
11. Introduce catheter before instilling saline –
lavage on inspiration.
12. Introduce catheter until a restriction is met or
until you can stimulate cough reflex.
13. Withdraw the catheter slowly while applying
intermittent suction. Suction should not be
applied for more than 15-20 seconds.
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FAR EASTERN UNIVERSITY
INSTITUTE OF HEALTH SCIENCES AND NURSING
DEPARTMENT OF NURSING
Figure 1. Dialysis
Indications: for patients with Figure 2. Hemodialysis system. Blood from an artery is pumped
• Fluid overload (A) into a dialyzer, where it flows through the synthetic capillary
tubes (B), which act as the semipermeable membrane (inset). The
• Increasing levels of serum K+ dialysate, which has a particular chemical composition, flows into
• Impending pulmonary edema the dialyzer around the capillary tubes that the blood flows through.
• Increasing acidosis The waste products in the blood diffuse across the semipermeable
• Poisoning or medication overdose membrane into the dialysate solution.
• Uremia
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FUNCTIONS OF HEMODIALYSIS • Gore-Tex or bovine carotid artery as artificial
1. Cleanses the blood of accumulated waste vein for blood flow
products • Procedure involves the anastomosis of the graft
2. Removes the by-products of protein to the artery
metabolism (urea, creatinine & uric acid) • Advantages: less danger of clotting and
3. Removes excessive fluids bleeding, can be used indefinitely, decreased
4. Maintains or restores the buffer system of the incidence of infection, and no external dressing
body required
5. Maintains or restores electrolyte levels • Disadvantages: cannot be immediately used
after insertion, venipuncture is required for
HEMODIALYSIS ACCESS dialysis, infiltration of needles (hematoma),
1. Subclavian vein catheter aneurysm in the fistula, and arterial steal
• Short-term, temporary, up to 6 weeks syndrome
• Filled with heparin and capped to maintain • Common complications: stenosis, infection,
patency between dialysis treatment. and thrombosis
• At risk for infection if left longer than 6
weeks HEMODIALYSIS COMPLICATIONS
• Chest pain
2. Femoral vein catheter- short-term, temporary • Dysrhythmias- may results from electrolyte
and pH changes or from removal or
3. External Arteriovenous shunt- direct catheter antiarrhythmic drugs during dialysis.
insertion at the artery and vein in the forearm or • Air embolism- rare but can occur if air enters
leg the vascular system
• Advantages: immediately used, no • Anemia- compounded by blood lost during
venipuncture hemodialysis)
• Disadvantages: external danger of • Gastric ulcers- may result from the
disconnecting and dislodging; risk for physiologic stress of chronic illness,
infection and skin erosion medication, and pre-existing medical
conditions
4. Internal Arteriovenous fistula- preferred • Patients with uremia report a metallic taste
method of permanent access for dialysis • Nausea and vomiting- due to rapid shift of
• Connects an artery to a vein (anastomosis) fluids and hypotension
• Needles are inserted into the vessel to • Bone pain and fractures- due to poor calcium
blood flow adequate to pass through the metabolism and renal osteodystrophy
dialyzer. • Itchiness- phosphorus deposits in the skin
• Requires time (2-3 months) to mature • Sleep disturbances- due to early morning or
before it can be used late afternoon dialysis schedules
• Uses stress ball for faster maturity • Shortness of breath- fluid accumulation in
• Maturity is required before the fistula is between dialysis treatments
used • Hypotension- occurs when fluid is removed
• Advantages: less danger of clotting and • Painful muscle cramps- occurs late in the
bleeding, can be used immediately, dialysis when electrolytes rapidly leave the
decreased incidence of infection, and no extracellular space
external dressing required • Disturbances of lipid metabolism
• Disadvantages: cannot be immediately (hypertriglyceridemia)
• Heart failure, coronary heart disease, angina,
used after insertion, venipuncture is
required for dialysis, infiltration of needles stroke, and peripheral vascular insufficiency
(hematoma), aneurysm in the fistula, and
HEMODIALYSIS NURSING MANAGEMENT
arterial steal syndrome
1. Promote Pharmacologic therapy
5. Internal Arteriovenous graft 2. Promote Nutritional and Fluid therapy
• Can be created by subcutaneously • Restriction of dietary protein, sodium,
potassium, phosphorus, and fluid intake
interposing a biologic, semibiologic, or
synthetic graft material between an artery 3. Meeting Psychosocial needs
4. Teach patient self-care
and vein
5. Continuing of care
• Usually, a graft is created when the
patient’s vessels are not suitable for
creation of an AVF
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PERITONEAL DIALYSIS • 5 to 2.5 liters of fluid per exchange
• In PD, the peritoneal membrane that covers the • Each exchange takes 30-40 minutes
abdominal organs and lines the abdominal wall
serves as the semipermeable membrane. A AUTOMATED PERITONEAL DIALYSIS (APD)
sterile dialysate fluid is introduced into the • aka Continues Cyclic PD (CCPD)/APD
peritoneal cavity through an abdominal catheter • Uses a machine to exchange the fluids
at intervals. • Each session lasts from 10-12 hours
• The goals of PD are to remove toxic substances • Usually done at night while patient sleeps
and metabolic wastes and to reestablish normal • Machine has 3 main functions:
fluid and electrolyte balance. o Heats PD fluid to body temperature
• PD may be the treatment of choice for patients o Controls time of exchange & amount of
with kidney disease who are unable or fluid used
unwilling to undergo hemodialysis or kidney o Monitors treatment (safety alarms)
transplantation.
• Patients who are susceptible to the rapid fluid, PROCEDURE FOR PERITONEAL DIALYSIS
electrolyte, and metabolic changes that occur I. PREPARING THE PATIENT:
during hemodialysis experience fewer of these 1. Explain the procedure & obtain a signed
problems with the slower rate of PD. consent
• Ultrafiltration (water removal) occurs in PD 2. Record baseline vital signs, weight & serum
through an osmotic gradient created by using a electrolytes
dialysate fluid with a higher glucose 3. Encouraged to empty bladder &bowel
concentration than the blood. 4. Administer broad-spectrum antibiotic agents as
ordered to prevent infection.
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SPECIAL CONSIDERATIONS: NURSING hypotension due to the combined effect
MANAGEMENT OF THE HOSPITALIZED of fluid removal with the dialysis
PATIENTS ON DIALYSIS treatment and the medication
1. Protecting vascular access 8. Preventing infection
• Assess the vascular access for patency • Patients with ESKD commonly have
• The extremity with the vascular access low WBC counts (and decreased
must not be used for taking blood pressure phagocytic ability), low RBC counts
or for obtaining blood specimens (anemia), and impaired platelet
• Tight dressings, restraints, or jewelry over function. Together, these pose a high
the vascular access must be avoided risk of infection and potential for
• Evaluate the bruit/ thrill at least every shift. bleeding after even minor trauma
Absence of palpable thrill or audible bruit 9. Caring for the catheter site
may indicate blockage or clotting in the • Recommended daily or 3 or 4 times-
vascular access weekly routine catheter site care is
2. Taking precautions during Intravenous typically performed during showering
therapy or bathing.
• The IV rate must be slow as possible • The exit site should not be submerged
• Accurate I&O records are essential in bathwater.
3. Monitoring symptoms of Uremia • The most common cleaning method is
• As metabolic end products accumulate, soap and water; liquid soap is
symptoms of uremia worsen. Patients recommended.
whose metabolic rate accelerates (those • During care, the nurse and patient need
receiving corticosteroid medications or to make sure that the catheter remains
parenteral nutrition, those with infections secure to avoid tension and trauma.
or bleeding disorders, those undergoing • The patient may wear a gauze or
surgery) accumulate waste products more semitransparent dressing over the exit
quickly and may require daily dialysis. site.
These same patients are more likely than 10. Administering medications
other patients receiving dialysis to • All medications and the dosage
experience complications. prescribed for any patient on dialysis
4. Detecting cardiac and respiratory must be closely monitored to avoid
complications those that are toxic to the kidneys and
• Cardiac and respiratory assessment must may threaten remaining renal
be conducted frequently. As fluid builds function.
up, fluid overload, heart failure, and • Medications are also scrutinized for
pulmonary edema develop. Crackles in the potassium and magnesium content;
bases of the lungs may indicate pulmonary those medications that contain them
edema. are avoided.
5. Controlling electrolyte levels and diet 11. Providing psychological support
6. Managing discomforts & pain
• Complications such as pruritus and pain
secondary to neuropathy must be LEARNING RESOURCES:
managed • https://youtube.com/watch?v=EU2skU3bgS8&fe
• Antihistamines for pruritus and ature=share
analgesics for pain
• Keep the skin clean and well REFERENCES:
Smeltzer, S. Bare, B., Hinkle, J. & Cheever, K
moisturized using bath oils, superfatted
(2010). Brunner & Suddarth’s Textbook
soap, and creams or lotions helps
of Medical-Surgical Nursing, 12th ed. Wolters
promote comfort and reduce itching. Kluwer/ Lippincott Williams& Wilkins,
• Instruct the patient to keep the nails Philadelphia, USA
trimmed to avoid scratching and Sole, M., Klein, D. & Moseley, M. (2013). Introduction to
excoriation also promotes comfort. Critical Care Nursing (6th ed.). Elsevier Inc. St.
7. Monitoring blood pressure Louis, Missouri, USA
• Hypertension in kidney disease is
common. It is usually the result of fluid
overload and, in part, oversecretion of
renin.
• Antihypertensive agents must be
withheld before dialysis to avoid
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