Professional Documents
Culture Documents
Orthognathic Surgery
A Report of 1000 Cases
Megan T. Robl, DDS, MDa,*, Brian B. Farrell, DDS, MDa,b,
Myron R. Tucker, DDSb
KEYWORDS
Complications Orthognathic Surgery
KEY POINTS
Multiple complications secondary to orthognathic surgery are evaluated based on a study of 1000
consecutive procedures.
Complications may develop in the preoperative, intraoperative, and postoperative stages of patient
care.
A thorough understanding of intraoperative and postoperative complications allows the appropriate
steps to be taken to maximize an esthetic and functional endpoint.
Multiple factors come into play when treating the complications, management of these situations,
individual with a dentofacial deformity to provide and resolution of the complications.
the most esthetic and functional result.1 Because
of the precise planning required and complexity
of the surgery, a multitude of levels exist from COMPLICATIONS RESULTING FROM
which errors can occur. For even the most experi- PREOPERATIVE PLANNING ERRORS
enced surgeon, unforeseen complications may The introduction of computer-aided surgical simu-
arise. Obstacles that may lead to complications lation has greatly enhanced the efficiency and ac-
can be divided as: curacy of orthognathic surgery. Computer-aided
Preoperative surgical simulation allows dentofacial deformities
Intraoperative to be better visualized and evaluated with relation
Postoperative to roll, pitch, and yaw. This 3-dimensional virtual
plan can then be transferred to the operating
In this article, the authors review complications room via a prefabricated splint. In traditional treat-
by studying those that occur in the previously ment planning, the workup involves reproduction
listed phases of treatment. One thousand consec- of the occlusal discrepancy on a semiadjustable
utive patients who underwent orthognathic sur- articulator through facebow transfer. The occlusal
gery performed by the senior author over a relationship is referenced through measurement of
5-year time period were evaluated. These cases fixed points. Manipulation can then be completed
included 337 mandibular osteotomies, 274 maxil- with the occlusal correction subsequently re-
lary osteotomies, and 389 combined osteotomies. mounted. Errors and inaccuracies in this model
oralmaxsurgery.theclinics.com
Table 1 provides a more precise breakdown of the surgery can contribute to compounding errors
procedures. Reviewing these cases provides a that are ultimately transferred to the operating
better understanding of the most common room and patient. Often, incorrect centric relation
a
Carolinas Center for Oral and Facial Surgery, 411 Billingsley Road, Suite 105, Charlotte, NC 28211, USA;
b
Department of Oral and Maxillofacial Surgery, Louisiana State University Health Sciences Center, New
Orleans, LA, USA
* Corresponding author.
E-mail address: meganroblddsmd@gmail.com
Table 1
a nasal packing in the post anesthesia care unit.
Procedures in the 1000 cases No patient returned for bleeding problems after hos-
pital discharge. In similar studies involving compli-
Procedure n cations in orthognathic surgery, Panula and
colleagues5 reviewed 655 patients, reporting 1
Mandibular osteotomies
case of a serious bleed. Kramer and colleagues6
Total 726 found extensive bleeding in 1.1% of a prospective
Isolated Mandible 337 study of 1000 patients. A survey by Lanigan7 of
Double jaw 389 approximately 800 oral and maxillofacial surgeons
Bilateral sagittal split osteotomy 684 found 18 cases of serious intraoperative bleeding
TOVRO 35 and 21 cases of postoperative bleeding.
Subapical (total) 7 Intraoperative complications may occur sec-
Maxillary osteotomies ondary to maxillary or mandibular osteotomies.
Total 663 Hemorrhagic complications associated with os-
Isolated Maxilla 247 teotomies through the posterior maxilla have
Double jaw 389 been well documented.8 Understanding the perti-
Single piece 321 nent head and neck anatomy, common sources
Segmental 342 of hemorrhage can be elucidated. Vessels most
often involved include the descending palatine ar-
records may not be identified during the preoper- teries, pterygoid venous plexus, masseteric artery,
ative phase of treatment, only to be discovered retromandibular vein, and the facial artery. Maxil-
during the intraoperative or postoperative period. lary venous bleeding most commonly involves
Use of virtual surgical planning eliminates many the pterygoid venous plexus. If the bleed is arterial,
of the uncertainties that go into preparing a case. the vessels most commonly associated are termi-
Computer-aided surgical simulation is addressed nal branches of the maxillary artery, often the de-
in the article “Virtual Surgical Planning in Orthog- scending palatine and sphenopalatine arteries.
nathic Surgery” by Drs Franco, Farrell, and Tucker Cauterizing the descending palatine vessels at
elsewhere in this issue. the time of surgery can prevent a postoperative
It is essential to understand the patient’s func- bleed. During pterygomaxillary dysjunction (maxil-
tional and esthetic challenges to ensure that sur- lary downfracture), the maxillary artery and its
gery will address their concerns. Proper patient branches are the most susceptible to injury.6
education is necessary to comprehend not only Bleeding may also result from a superiorly posi-
the surgery itself, but also the postoperative tioned pterygoid plate fracture after pterygomaxil-
course. Visual aids at the preoperative visits, using lary dysjunction that results in internal carotid
current computer programming software (eg, Dol- artery hemorrhage. The sharp edges of the de-
phin Aquarium, Dolphin Software, Chatsworth, CA, tached pterygoid plates forced back during the
USA) in addition to prediction imaging, can provide downfracture are implicated in lacerating the inter-
the patient with further insight into their treatment. nal carotid artery and jugular vein.6 Should
Patient willingness and motivation directly impact bleeding occur during surgery, the following steps
the patient’s satisfaction and compliance in the allow one to properly achieve hemostasis.
postoperative period.
In this series of 1000 patients, there were no 1. Initial measures include hypotensive anesthesia,
significant complications identified as a result of adequate visualization, and direct pressure.
errors in the presurgical planning phase. 2. Hemoclip or electrocautery may be utilized in
addition to local measures, such as Surgicel
(oxidized cellulose sponges; Ethicon, Somer-
INTRAOPERATIVE COMPLICATIONS
ville, NJ, USA) or Avitene (microfibrillar bovine
Hemorrhage
collagen; Medline, Mundelein, IL, USA).
A review of the literature reveals a number of reports 3. In cases where there is persistent low-pressure
concerning bleeding. All indicate that serious bleeds bleeding (pterygoid venous plexus area) packing
are rare.2–4 No intraoperative bleeding problems often stops the oozing, but once removed
requiring secondary intervention were observed in bleeding continues. In such cases, the osteot-
the 1000 cases reviewed. One patient returned to omy can be completed and fixated with packing
the operating room to control and reduce bleeding placed, leaving the tail of packing exposed
immediately after a Lefort I osteotomy. The de- through the posterior aspect of the incision. The
scending palatine vessels were recauterized and a packing is then easily removed on the following
surgical pack was placed. Three patients required day, usually with resolution of the bleeding.
Downloaded for Anonymous User (n/a) at University of Manitoba from ClinicalKey.com by Elsevier on October 30,
2023. For personal use only. No other uses without permission. Copyright ©2023. Elsevier Inc. All rights reserved.
Complications in Orthognathic Surgery 601
Downloaded for Anonymous User (n/a) at University of Manitoba from ClinicalKey.com by Elsevier on October 30,
2023. For personal use only. No other uses without permission. Copyright ©2023. Elsevier Inc. All rights reserved.
602 Robl et al
Downloaded for Anonymous User (n/a) at University of Manitoba from ClinicalKey.com by Elsevier on October 30,
2023. For personal use only. No other uses without permission. Copyright ©2023. Elsevier Inc. All rights reserved.
Complications in Orthognathic Surgery 603
separation. The different types of unfavorable Fig. 4. Facial portion of inferior border staying with
splits and their management are described. proximal segment creating a J-shaped curvature.
Downloaded for Anonymous User (n/a) at University of Manitoba from ClinicalKey.com by Elsevier on October 30,
2023. For personal use only. No other uses without permission. Copyright ©2023. Elsevier Inc. All rights reserved.
604 Robl et al
2. Proximal segment fractures with insufficient In a review of the 684 bilateral sagittal split os-
bone for sagittal overlap (Fig. 6): The mandible teotomy surgeries, bad splits were observed in
remains intact with the osteotomy incomplete 3.9% of the cases. This included a total of 11 major
and there is a loss of a large portion of buccal fractures requiring significant revision of the os-
segment. There is inadequate bone available teotomy or alteration of the fixation technique. In
for sagittal overlap. Management involves verti- 16 cases, there were minor bone fractures that
cal ramus osteotomy on the remaining intact did not require significant modification of the in-
portion of the ramus with control of the prox- tended surgery. None of the bad splits altered
imal segment. The proximal segment can then the overall patient outcome. The patients were
be fixed to the distal segment. The buccal frag- not placed into maxillomandibular fixation and
ment can then be used to overlap the defect. there were no resulting infections.
3. Proximal segment fractures with mandible
separated (Fig. 7): The osteotomy is achieved
Oro–Antral Communication
with the mandible separated and in multiple
pieces. There is a resulting proximal segment During maxillary surgery, design of the segmental
with discontinuity. Management includes rees- osteotomy must keep in mind the relevant anat-
tablishing continuity using small bone plates. omy. Bone is thickest in the midline where tissue
The proximal segment can then be reattached is the thinnest. Osteotomies in the midline are
to the distal segment using a screw technique. more likely to result in palatal tears and these
Any areas of overlap may be helpful to allow may be less likely to heal than when a tear occurs
initial screw stabilization. laterally, in thicker tissue.17 Therefore, parasagittal
4. Lingual segment fracture (Fig. 8): Prevention of cuts for a segmental osteotomy near the lateral
lingual segment fractures may come from early aspect of the nasal floor places them over thin
removal of third molars approximately 9 months bone and thick, more elastic, vascularized tissue
to 1 year before an osteotomy.16 In addition, (Fig. 9). Despite proper site selection and careful
there should be adequate thickness of bone in surgery, violation of palatal mucosa may occur.
the lingual segment and careful separation of In most cases, small tears do not need treatment
the superior portion of the osteotomy with and heal uneventfully. If a larger opening is pre-
avoidance of fulcruming on the lingual seg- sent, it can be managed by placing a very small
ment. Management involves fixation of the amount of collagen membrane layer in the tear;
proximal segment to the distal segment using the area is dried and then sealed with dermabond
bone plates followed by screw fixation of the (Fig. 10).
lingual segment to the proximal segment. This In some cases, a persistent fistula may present.
provides stability to the distal segment as well Initial treatment includes routine sinus manage-
as the fractured lingual segment. ment with decongestants, nasal spray, and
Fig. 6. (A) Proximal segment with insufficient bone for sagittal overlap managed with vertical osteotomy of
remaining ramus. (B) Buccal fragment then used to overlap defect.
Downloaded for Anonymous User (n/a) at University of Manitoba from ClinicalKey.com by Elsevier on October 30,
2023. For personal use only. No other uses without permission. Copyright ©2023. Elsevier Inc. All rights reserved.
Complications in Orthognathic Surgery 605
POSTOPERATVE COMPLICATIONS
After orthognathic surgery, some degree of
postoperative discomfort is expected. Some pa-
tients may exhibit extreme pain, prolonged
swelling, marked bruising, and infection.2 How-
ever, all patients described an initial postoperative
complaint of a sore throat.1 Fortunately, the expec-
tant neurosensory deficit masks some of the
discomfort in the recovery period. Additionally,
every patient will have a varying degree of edema
dependent on the time in surgery, extent of tissue
manipulation, skin type, and any nonsteroidal
anti-inflammatory drug or aspirin use. For the pur-
poses of this study, bruising was recorded if there
was obvious facial discoloration at the first postop-
Fig. 7. Proximal segment fracture with the mandible erative appointment (usually 5–7 days postopera-
separated managed with reestablishing continuity
tively). Only 20% of patients showed signs of
using small bone plates. Screw technique then used
to reattach proximal to distal segment.
bruising at the first postoperative visit.
Infection
antibiotics. Obturation of open fistulas using a soft
“suck-down” material made from the final model Infection is obviously a potential complication with
usually results in significant shrinkage or complete any surgical procedure. Fortunately, the rates of
elimination of the fistula. Among the 1000 cases, infection are very low with orthognathic surgery.
Of the infections, 21 were in the mandible and 4
in the maxilla. The results studied were divided
into minor and major infections. Minor infections
were those demonstrating superficial wound in-
fections, and were treated with small incisions
and drainage with continued antibiotic coverage.
Major infections were defined as those requiring
more aggressive debridement, bone grafting, or
both. Three such cases occurred in the mandible
and 1 in the maxilla. This accounts for an overall
infection rate of 2.4% in the mandible and 0.5%
in the maxilla.
Vascular Compromise
Problems with wound healing may be owing to a
variety of causes. In maxillary surgery particularly,
this may involve some degree of avascular necro-
sis of bone and soft tissue (Fig. 11). Contributing
factors associated with avascular necrosis include:
1. Smoking (local and systemic impact)
2. Osteotomy design
3. Flap design and management
Fig. 8. Management of lingual segment fracture 4. Segment movement/rotation
utilizing small bone plate then screw fixation of 5. Stretching and pinching of the tissue
proximal to distal segment. 6. Splints
Downloaded for Anonymous User (n/a) at University of Manitoba from ClinicalKey.com by Elsevier on October 30,
2023. For personal use only. No other uses without permission. Copyright ©2023. Elsevier Inc. All rights reserved.
606 Robl et al
Fig. 9. Illustration (A) and clinical photo (B) to illustrate design of segmental osteotomy with parasagittal cuts to
best avoid palatal tears.
Avascular necrosis may occur between osteot- the cases resulted in the loss of 2 teeth. All other
omy cuts in segmental maxillary surgery. Manage- cases were managed with local care without surgi-
ment involves the following steps: cal debridement. Two of the patients eventually re-
quired gingival grafts.
1. Verify there is no splint impingement
2. Eliminate mobility Endodontic Therapy
3. Utilize a tissue dressing such as Vaseline gauze
After orthognathic surgery, loss of vascularity to
Antibiotics (local or systemic) may be used at the dentition is rare, but initial loss of response to
the discretion of the surgeon. Hyperbaric oxygen pulpal stimulation is common. Long-term sup-
may aid in a more expedient demarcation of vital pressed response to stimulation can occur, but
and nonvital tissue; however, it does not affect does not necessarily mean a tooth requires end-
the ultimate outcome.18–20 odontic therapy. Teeth, like all other tissue, can
For more aggressive treatment, provide debride- bruise. This becomes apparent with initial discol-
ment only when and where the area of necrosis is oration. Although some teeth may eventually
well demarcated. Minimal bone should be re- have necrosis of the pulp and require endodontic
moved usually involving only conspicuous necrotic treatment, many teeth recover without treatment,
sequestra. One should allow granulation through return to normal coloration, and respond to pulp
secondary intention rather than primary closure. testing. In our group of 1000 patients, 4 teeth
Ultimately, the area may require removal of teeth adjacent to segmental surgical sites required root
with subsequent bone grafting and implant place- canal therapy. Three of the teeth were associated
ment. The authors observed cases of necrosis, pri- with maxillary surgery (0.9% of segmental cases).
marily evidenced by loss of gingival tissue. All of Four teeth in 3 other patients required endodontic
these cases were segmental maxillary surgery treatment not clearly associated with their orthog-
and all of these patients were smokers. One of nathic surgery.
Fig. 10. Management of palatal tear (A) with collagen membrane layer and dermabond at the time of surgery
and (B) 8 weeks postoperatively.
Downloaded for Anonymous User (n/a) at University of Manitoba from ClinicalKey.com by Elsevier on October 30,
2023. For personal use only. No other uses without permission. Copyright ©2023. Elsevier Inc. All rights reserved.
Complications in Orthognathic Surgery 607
Fig. 11. (A) Avascular necrosis. Tissue appearance immediately after surgery ultimately managed with Vaseline
gauze (B). (C) Appearance 2 months after surgery.
Fig. 12. Profile view (A), frontal view (B), and worm’s eye view (C) of nasal deformities after orthognathic surgery.
Tip over-rotation (A, B) illustrated along with septal deviation (C).
Downloaded for Anonymous User (n/a) at University of Manitoba from ClinicalKey.com by Elsevier on October 30,
2023. For personal use only. No other uses without permission. Copyright ©2023. Elsevier Inc. All rights reserved.
608 Robl et al
Fig. 13. Intraoral approach to septal correction. 1. Limiting patient function and thus mobility through
heavy elastics/maxillomandibular fixation
In this 1000 case experience, 2 patients (0.2%) 2. More aggressive approach of reoperation with
who underwent a bilateral sagittal split osteotomy reinforcement of the fixation
with rigid internal fixation demonstrated malocclu- If the problem is addressed later, then fixation
sions and could not function into the splint on the may be reinforced, intraoral debridement per-
first postoperative day. These patients were re- formed, and bone grafting done, if necessary, in
turned to the operating room and the fixation was the absence of infection. This approach parallels
revised without any further complication. An impor- that for managing nonunion of a mandibular frac-
tant point to keep in mind is that subtle occlusal dis- ture. In this group of 1000 patients (726 mandibular
crepancies may be overcome with guidance elastics osteotomies), there were 2 cases of fixation failure
and improved neuromuscular reprogramming. in the mandible. One patient required debridement
and replacement of fixation; the second case
Temporomandibular Joint Dysfunction
required debridement, replacement of fixation,
In patients with preexisting temporomandibular and bone grafting.
joint dysfunction, thorough documentation of mus- In conservative management of the mobile
cle and joint dysfunction is essential. Orthognathic maxilla, consideration is given to soft diet, discon-
surgery can potentially benefit joint dysfunction tinuation or decreased strength of elastic traction,
through the establishment of a balanced, stable, modified splint to balance occlusion, local and
and reproducible occlusion; however, this is systemic management of infection, elimination of
difficult to predict with any degree of certainty. parafunctional habits, and close observation. Sur-
Temporomandibular joint symptoms may improve, gical management in a malunion or nonunion of
deteriorate, or remain similar to that before sur- the maxilla involves:
gery. Eighty-six patients had interincisal opening
of less than 40 mm after surgery. Eighty-two of 1. Recreation of the osteotomy with aggressive
the procedures were associated with mandibular mobilization
osteotomies. Forty-two of the asymptomatic pa- 2. Removal of all fibrous tissue
tients initially developed new temporomandibular 3. Passive repositioning of segments
joint symptoms. Less than 1% of these individuals 4. Rigid fixation to resist segment displacement
had symptoms that persisted for greater than (consider auxiliary fixation, transpalatal support)
6 months postoperatively, although 3 of the pa- 5. Grafting for continuity
tients did eventually require conservative therapy One case of a nonunion of the maxilla resulted in
and arthroscopy. the need for revision of the osteotomy, fixation and
bone grafting.
Fixation Failure
According to a study by Falter and colleagues,21
One of the most common, significant postoperative the need for plate removal was indicated in infec-
complications is a fixation failure of the mandibular tion, clinical irritation, hardware fracture, and patient
Downloaded for Anonymous User (n/a) at University of Manitoba from ClinicalKey.com by Elsevier on October 30,
2023. For personal use only. No other uses without permission. Copyright ©2023. Elsevier Inc. All rights reserved.
Complications in Orthognathic Surgery 609
request. In addition, resorbable plates and screws associated with Lefort I osteotomies. J Oral Maxillo-
have also been used for fixation in orthognathic sur- fac Surg 1990;48:561.
gery. In a study comparing resorbable with titanium 8. Lanigan D. Vascular complications associated with
fixation plates, greater complications rates were orthognathic surgery. Oral Maxillofac Surg Clin
noted in the group who received a resorbable plate North Am 1997;9(2):231–50.
(18.3%) compared with the titanium group (8.6%). 9. Bouloux G, Perciaccante V. Massive hemorrhage
These patients had a greater prevalence of postop- during oral and maxillofacial surgery: ligation of the
erative open bite and surgical relapse.22 external carotid artery or embolization? J Oral Max-
illofac Surg 2009;67:1547–51.
10. Shetty V, Bertolami C. Wound healing. In: Miloro M,
SUMMARY
editor. Peterson’s principles of oral and maxillo-
Orthognathic surgery provides an effective means facial surgery. 2nd edition. London: BC Decker;
for the correction of facial disharmonies to provide 2004. p. 3–17.
patients with a functional occlusion. With any 11. Binkert C. 2002. Embolization tools and techniques.
procedure, regardless of surgeon experience, Supplement to Applied Radiology. July 55–64.
complications may arise. In reviewing these com- 12. Svartz K, Ahlborg G, Finne K, et al. Nerve distur-
plications, a better understanding of how to not bances after sagitttal split osteotomy. Int J Oral
only manage them, but also to prevent their occur- Surg 1983;12:279.
rence can be gained. By educating all surgical pa- 13. Miloro M. Microneurosurgery. In: Miloro M, editor.
tients through informed consent, we can prepare Peterson’s principles of oral and maxillofacial
them for what will come with the surgical proce- surgery. 2nd edition. London: BC Decker; 2004. p.
dure. Most complications are common to orthog- 819–38.
nathic surgical procedures and can be discussed 14. Schendel SA, Epker BN. Results after mandibular
with the patent in detail before the procedure. advancement surgery: an analysis of 87 cases.
Continued advances in the field of orthognathic J Oral Surg 1980;38:265–82.
surgery, especially with the inclusion of virtual sur- 15. Perez D, Ellis E. Sequencing bimaxillary surgery:
gical planning, have served to modernize our mandible first. J Oral Maxillofac Surg 2011;69:
treatment planning and bring patients to an ideal 2217–24.
result. 16. Van Sickels J. Prevention and management of com-
plications in orthognathic surgery. In: Miloro M,
REFERENCES editor. Peterson’s principles of oral and maxillofacial
surgery. 2nd edition. London: BC Decker; 2004. p.
1. Kim SG, Park SS. Incidence of complications and 1247–66.
problems related to orthognathic surgery. J Oral 17. Perciaccante V, Bays R. Maxillary orthognathic sur-
Maxillofac Surg 2007;65:2438. gery. In: Miloro M, editor. Peterson’s principles of
2. Steel B, Cope M. Unusual and rare complications of oral and maxillofacial surgery. 2nd edition. London:
orthognathic surgery: a literature review. J Oral BC Decker; 2004. p. 1179–204.
Maxillofac Surg 2012;70:1678. 18. Lanigan DT, Hey JH, West RA. Aseptic necrosis
3. Morris D, Lo LJ, Margulis A. Pitfalls in orthognathic following maxillary osteotomies: report of 36 cases.
surgery: avoidance and management of complica- J Oral Maxillofac Surg 1997;55:51.
tions. Clin Plast Surg 2007;34:e17–29. 19. Epker BN. Vascular considerations in orthognathic
4. Bays R, Bouloux G. Complications of orthognathic surgery. J Oral Surg 1984;57:473.
surgery. Oral Maxillofac Surg Clin North Am 2003; 20. Pereira F, Yaedu R, SantAna A, et al. Maxillary
15:229–42. aseptic necrosis after Lefort I osteotomy: a case
5. Panula K, Finne K, Oikarinen K. Incidence of compli- report and literature review. J Oral Maxillofac Surg
cations and problems related to orthognathic sur- 2010;68:1402–7.
gery: a review of 655 patients. J Oral Maxillofac 21. Falter B, Schepers S, Vrielinck L, et al. Plate
Surg 2001;59:1128. removal following orthognathic surgery. Oral Surg
6. Kramer FJ, Baethage C, Swennen G, et al. Intra- and Oral Med Oral Pathol Oral Radiol Endod 2011;
perioperative complications of the LeFort I osteot- 112:737–43.
omy: A prospective evaluation of 1000 patients. J 22. Ahn Y, Kim S, Baik S, et al. Comparative study
Craniofacial Surg 2004;15:971. between resorbable and nonresorbable plates in
7. Lanigan DT, Hey JH, West RA. Major vascular com- orthognathic surgery. J Oral Maxillofac Surg 2010;
plications of orthognathic surgery: Hemorrhage 68:287–92.
Downloaded for Anonymous User (n/a) at University of Manitoba from ClinicalKey.com by Elsevier on October 30,
2023. For personal use only. No other uses without permission. Copyright ©2023. Elsevier Inc. All rights reserved.