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Pfizer Inc.
Recommendation Price 12-Mo. Target Price Report Currency Investment Style
BUY « « « « « USD 30.55 (as of market close Oct 30, 2023) USD 35.00 USD Large-Cap Blend
Equity Analyst Sel Hardy
GICS Sector Health Care Summary Pfizer ranks as one of the world's largest pharmaceutical companies, offering a wide range of
Sub-Industry Pharmaceuticals drugs across a broad therapeutic spectrum.
Key Stock Statistics (Source: CFRA, S&P Global Market Intelligence (SPGMI), Company Reports)
52-Wk Range USD 54.93 - 30.02 Oper.EPS2023E USD 1.65 Market Capitalization[B] USD 172.48 Beta 0.56
Trailing 12-Month EPS USD 4.82 Oper.EPS2024E USD 3.27 Yield [%] 5.37 3-yr Proj. EPS CAGR[%] 3
Trailing 12-Month P/E 6.34 P/E on Oper.EPS2023E 18.52 Dividend Rate/Share USD 1.64 SPGMI's Quality Ranking B+
USD 10K Invested 5 Yrs Ago 8,981.0 Common Shares Outstg.[M] 5,645.00 Trailing 12-Month Dividend USD 2.04 Institutional Ownership [%] 71.0
Revenue/Earnings Data
Redistribution or reproduction is prohibited without written permission. Copyright © 2023 CFRA. This document is not intended to provide personal investment advice and it does not take into account the specific investment
objectives, financial situation and the particular needs of any specific person who may receive this report. Investors should seek independent financial advice regarding the suitability and/or appropriateness of making an investment
or implementing the investment strategies discussed in this document and should understand that statements regarding future prospects may not be realized. Investors should note that income from such investments, if any,
may fluctuate and that the value of such investments may rise or fall. Accordingly, investors may receive back less than they originally invested. Investors should seek advice concerning any impact this investment may have on
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otherwise indicated, there is no intention to update this document.
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Stock Report | October 30, 2023 | NYSE Symbol: PFE | PFE is in the S&P 500
Pfizer Inc.
Business Summary Sep 15, 2023 Corporate information
CORPORATE OVERVIEW. PFE is one of the world’s largest biopharmaceutical companies, with extensive Investor contact
operations in drug development, manufacturing, and marketing. The company’s growth is also augmented F. M. DeMartino (212 733 2323)
by frequent acquisitions. Pfizer’s largest market is the U.S., where 42% of 2022 sales were generated,
followed by developed Europe at 22%, emerging markets at 20%, and developed Rest of the World at 16%. Office
Total revenues in 2022 stood at $100.3 billion, up $19.0 billion (+23%). PFE’s new oral Covid medication, 66 Hudson Boulevard East, New York, New York, 10001-
Paxlovid, was the source of virtually all of that year-over-year increase (+$18.9 billion). The PFE Covid-19 2192
vaccine, Comirnaty, registered sales of $37.8 billion in 2022, which is considerable, but up only $1.0 billion
from 2021 (+2.7%). Telephone
212 733 2323
Excluding Corminaty and Paxlovid, the remainder of PFE grew revenues 2.1% in 2022 to $43.6 billion. Key
contributors to 2023 growth, in our view, should include the recently-acquired Nurtec and Vyndaqel/ Fax
Vyndamax (although the latter faces a loss of exclusivity in 2024). Vyndaqel is a treatment for N/A
cardiomyopathy and polyneuropathy, which generated revenues of $2.4 billion in 2022, up 21% versus 2021.
Website
DRUG PORTFOLIO. Pfizer’s drug portfolio is among the most diverse in the global drug market, in our view.
www.pfizer.com
Not including Covid-related vaccines, the company’s top-selling drugs are Eliquis ($6.5 billion) for stroke
and embolism, which grew 9% in 2022; Ibrance ($5.1 billion, down 6%); and the Prevnar family of vaccines
($6.3 billion in 2022 sales, up 20%). Officers
It is critical for drug companies like Pfizer to consistently have successful new drugs that are in growth Executive VP and Chief Chief Financial Officer &
mode, offsetting older drugs that are declining in sales due to loss of exclusivity or competition from new Digital & Technology Executive VP
and improved treatments. An example of this type of decline is Pfizer’s arthritis drug, Celebrex, which was Officer D. M. Denton
under the recently spun-off Upjohn business’ portfolio. Celebrex sales peaked at around $2.9 billion in 2013, L. L. Fonseca
Chairman of the Board &
but had fallen to $719 million in 2019 after its U.S. patents expired in 2014. Over the next five years, Pfizer Senior VP, Controller & CEO
has several key U.S. patent expirations occurring that it hopes to offset with growth in newer drugs. Key U.S. Principal Accounting A. Bourla
patent expirations include Ibrance in 2023, Vyndaqel/Vyndamax in 2024, and Xeljanz ($2.5 billion in 2021 Officer
revenues) in 2025. J. B. Damico
MARKET PROFILE. Worldwide total prescription drug sales are projected to grow at a compound annual
growth rate (CAGR) of 7.4% between 2020 and 2026 and reach $1.4 trillion by 2026, according to forecasts Executive VP & General
from EvaluatePharma. A key driver of this growth should be the aging of developed populations, especially in Counsel
the U.S., as baby boomers age into their prime years for health care needs. Emerging markets will likely see D. M. Lankler
materially faster growth in prescription sales than developed markets through 2026, however. This is due, in
our view, to emerging market demand for pharmaceuticals being spurred by rising standards of living as Board Members
global middle classes expand and gain access to advanced health care, and also as these developing A. Bourla R. E. Blaylock
markets’ governments increase their health care spending.
C. T. Hagel S. Desmond-Hellmann
RESEARCH AND DEVELOPMENT. In an effort to continuously offset declining sales of older drugs, Pfizer
spends heavily on research and development (R&D) to keep new drugs coming out of its pipeline and into D. R. Littman S. Gottlieb
the global drug markets. Pfizer’s R&D spending dropped to $11.4 billion in 2022 (11% of sales) from $13.8 H. H. Hobbs S. J. Hockfield
billion in 2021 (17% of sales). PFE’s R&D spend over the last five-year period (2018 through 2022) indicates J. B. Quincey S. M. Nora Johnson
a weighted average of 17%, so a reduction in R&D is possible and sustainable if supplemented by M&A
activity. J. C. Smith S. Narayen
IMPACT OF MAJOR DEVELOPMENTS. Pfizer has been flush with cash following the financial success of its J. J. Echevarria
Covid-19 vaccine and medication. With the proceeds, the company has been making strategic acquisitions.
From this perspective, we see the $2.26 billion Trillium Therapeutics acquisition in 2021 as positive. Trillium Domicile Auditor
is a clinical stage immuno-oncology firm developing innovative cancer therapies serving the fast growing Delaware KPMG LLP - Klynveld Peat
oncology market. Marwick Goerdeler
On March 13, 2023, Pfizer and Seagen entered into a definitive merger agreement under which Pfizer Founded
agreed to acquire Seagen for $229 in cash per share, a 33% premium to the March 10, 2023 closing price. 1849
The deal is expected to close late 2023 or early 2024, pending regulatory approvals. The FTC is investigating Employees
the proposed merger on antitrust concerns and requested a second round of documentation mid-July. We 83,000
do not foresee a major issue and expect the transaction to close along the anticipated timelines.
Upjohn business: Pfizer and Mylan spun off Pfizer’s off-patent brand drug business, Upjohn (20% of sales), Stockholders
and all MYL assets into a new company (Viatris) in 2020. Upjohn sold many well-known drugs, like Viagra 128,767
and Lipitor, that were once major growth drivers for PFE, but have been in decline after losing patent
protection.
The Covid-19 vaccine: Pfizer jointly developed a two-dose mRNA-based vaccine with Biontech in less than a
year with a 90% efficacy to prevent Covid-19. The vaccine was the first to receive the emergency use
authorization in any developed country in December 2020, first in the U.K., then in the U.S.
DRUG PRICING NEGOTIATIONS: The first list of 10 top-selling prescription drugs subject to negotiations with
Medicare was announced by the CMS on August 29, 2023. Eliquis, jointly developed and commercialized by
Bristol Myers Squibb and Pfizer is on the list. During June 2022 to May 2023, Medicare Part D spending on
Eliquis was at $16.5 billion. Eliquis’ patent protection is expected to last until 2028. Xtandi, the key drug to
treat prostate cancer, jointly commercialized by Pfizer and Astellas, could be included in the next rounds of
negotiations, in our view.
FINANCIAL TRENDS. In the four-year period 2018-2022, revenues grew at a CAGR of 25%, although were
skewed towards 2021 given the impact of PFE’s Covid-19 vaccine. Over the same period, return on capital,
which averaged 5.0% between 2019 and 2020, jumped to 15% in 2021 and almost to 20% in 2022.
Redistribution or reproduction is prohibited without prior written permission. Copyright © 2023 CFRA. 2
Stock Report | October 30, 2023 | NYSE Symbol: PFE | PFE is in the S&P 500
Pfizer Inc.
Quantitative Evaluations Expanded Ratio Analysis
Source: S&P Global Market Intelligence. Data may be preliminary or restated; before results of discontinued operations/special items. Per share data adjusted for stock dividends; EPS diluted.
E-Estimated. NA-Not Available. NM-Not Meaningful. NR-Not Ranked. UR-Under Review.
Redistribution or reproduction is prohibited without prior written permission. Copyright © 2023 CFRA. 3
Stock Report | October 30, 2023 | NYSE Symbol: PFE | PFE is in the S&P 500
Pfizer Inc.
Sub-Industry Outlook Industry Performance
Our outlook for the pharmaceutical sub-industry is more active stance on antitrust review, but has GICS Sector:Health Care
neutral. We expect an improved outlook for the not moved so far to block them. We think there Sub-Industry:Pharmaceuticals
rest of 2023, partly predicated on a return to may be increased scrutiny for potential Based on S&P 1500 Indexes
normalcy, with improved utilization and electives pharmaceutical M&A, especially following the Five-Year market price performance through Oct 28, 2023
demand. Contributions from new launches with a FTC’s lawsuit against Amgen’s acquisition of
focus on Alzheimer’s disease, obesity, and Horizon, which was later settled, and
oncology will remain key growth drivers as a successfully closed.
number of pharmaceutical firms see loss of Global minimum taxation of at least 15% on
exclusivities and face increasing competition. We multinationals with more than $890 million in
also expect tough comparisons Y/Y due to lower annual revenue proposed by the U.S. and
demand for Covid-19 vaccines and treatments. backed by 137 countries is scheduled to take
Going forward, we expect Covid-related activity to effect at the beginning of 2024. We foresee
shift to a seasonal phenomenon, like the flu. While that this would potentially hurt the bottom-line
there may be further surges in Covid-related sales, profitability of large multinational
we expect a more annuity-like pattern to such pharmaceuticals.
sales.
We expect major generic makers to continue to
One concern is the possibility of a recession, which struggle due to lower-cost emerging market
could weigh on electives demand. Yet, key competition. We think India-based generic
therapeutic areas seen as essential, such as makers will continue to take market share from
oncology and immunology, are likely to see developed nation firms due to lower production
ongoing demand, in our view, and could be costs. We also expect Chinese pharmaceuticals
relatively less susceptible to slowdowns. to shift some of their resources away from
CFRA thinks health care policy risks are on the generics and focus on more lucrative
rise. Reducing drug prices continues to be a innovative drugs, which could increase
bipartisan issue as both parties aim for more competitive pressures. We also see a rise in
affordable drug prices for Americans. The Inflation biosimilars, which, while more expensive to
Reduction Act (IRA) allows Medicare to directly produce than generics, will likely get a longer
negotiate prices on the top 10 branded drugs for period of time before the field gets crowded
Medicare Part D coverage, with revised pricing with other biosimilars in the same category.
taking effect in January 2026, and later expanding YTD through October 13, the S&P Composite
to 20 branded drugs in 2028. The Centers for 1500 Pharmaceuticals Index was down 0.8%
Medicare & Medicaid Services published the list of vs. an 11.6% increase for the S&P Composite NOTE: A sector chart appears when the sub-industry does not have
the first 10 top-selling prescription drugs selected 1500 Index. In 2022, the S&P Pharmaceuticals sufficient historical index data.
for negotiations on August 29, 2023, which Index returned a gain of 5.5% vs. a 19.1% drop All Sector & Sub-Industry information is based on the Global Industry
includes drugs from large U.S. Pharmaceutical for the S&P Composite 1500. Classification Standard (GICS).
companies (BMY, PFE, LLY, MRK, JNJ). The Past performance is not an indication of future performance and should
negotiated maximum fair prices for these drugs / Sel Hardy not be relied upon as such.
will be published by September 1, 2024. We think Source: CFRA, S&P Global Market Intelligence
the IRA may also have implications for companies.
For example, if pharmaceutical firms know that
new blockbusters may get negotiated down, they
may price them higher at launch. The act may also
have implications as to where firms decide to
invest.
We also note that the FTC appears to be taking a
Pfizer Inc. PFE NYSE USD 30.11 170,000.0 -6.2 -34.2 6.0 15.58 5.4 23.1 37.4
AstraZeneca PLC AZN NasdaqGS USD 61.89 190,437.0 -8.9 7.4 17.0 N/A 2.3 16.8 35.8
Bristol-Myers Squibb Company BMY NYSE USD 51.02 103,813.0 -11.9 -31.6 7.0 N/A 4.5 26.9 47.1
GSK plc GSK NYSE USD 34.56 70,391.0 -6.7 5.6 11.0 N/A 3.9 33.2 46.2
Merck & Co., Inc. MRK NYSE USD 102.82 260,908.0 -1.1 3.1 33.0 N/A 2.8 N/A N/A
Novartis AG NVS NYSE USD 92.27 190,987.0 -8.0 16.0 14.0 N/A 2.5 16.5 28.5
Royalty Pharma plc RPRX NasdaqGS USD 26.21 11,766.0 -1.8 -37.6 46.0 N/A 3.1 4.7 36.2
Sanofi SNY NasdaqGS USD 43.13 107,818.0 -18.6 3.7 10.0 N/A 3.2 N/A N/A
Teva Pharmaceutical Industries Limited TEVA NYSE USD 8.12 9,100.0 -18.9 -6.6 4.0 N/A N/A -26.6 65.1
Viatris Inc. VTRS NasdaqGS USD 8.77 10,520.0 -8.6 -11.1 3.0 4.50 5.5 9.1 43.5
Zoetis Inc. ZTS NYSE USD 156.03 71,823.0 -10.7 3.2 31.0 121.26 1.0 48.0 57.8
*For Peer Groups with more than 10 companies or stocks, selection of issues is based on market capitalization.
NA-Not Available; NM-Not Meaningful.
Note: Peers are selected based on Global Industry Classification Standards and market capitalization. The peer group list includes companies with similar characteristics, but may not include all the companies within the same
industry and/or that engage in the same line of business.
Redistribution or reproduction is prohibited without prior written permission. Copyright © 2023 CFRA. 4
Stock Report | October 30, 2023 | NYSE Symbol: PFE | PFE is in the S&P 500
Pfizer Inc.
Analyst Research Notes and other Company News
October 31, 2023 We lower our target by $5 to $43, 11.4x our 2024 EPS, below PFE’s 10-year
10:35 AM ET... CFRA Retains Buy Opinion on Shares of Pfizer Inc. (PFE 29.99****): historical forward P/E average. We cut our 2023 EPS view by $0.21 to $3.44 and
We reduce our 12-month target by $5 to $35, 10.7x our 2024 EPS, a discount to 2024’s by $0.34 to $3.78. Q2 EPS of $0.78 vs. $2.04 was $0.09 above consensus,
PFE’s 10-year historical forward P/E average. We lower our 2023 EPS view by $0.02 but $0.11 below our estimate. Q2 revenues of $12.7B (-54% Y/Y) underperformed
to $1.65 and our 2024 estimate by $0.26 to $3.27. Q3 LPS of $0.17 versus EPS of consensus by $664M as revenue declines in both Comirnaty (Covid-19 vaccine, -
$1.78 was $0.17 below the S&P Capital IQ consensus and $0.18 below our estimate. 82% Y/Y) and particularly in Paxlovid (antiviral, -98% Y/Y) were above expectations.
Q3 revenues of $13.2B (-42% Y/Y) were $197M below consensus and $566M below While both Comirnaty and Paxlovid sales guidance for 2023 were unchanged at
our estimate as Paxlovid (antiviral to treat Covid-19) revenues of $202M (-97% Y/Y) $13.5B and $8B, respectively, PFE lowered the high end of its 2023 sales guidance
were significantly below our forecasts. PFE continued to face difficult comparisons range to $70B from $71B as it cut its non-Covid operational sales growth to 6% Y/Y
on the back of sharp declines in Covid-19-related revenues, with Comirnaty (Covid- from 8% Y/Y. To address ongoing concerns, in our view, regarding the delay or non-
19 vaccine) sales also down 70% Y/Y. Yet, PFE reaffirmed its 2023 sales and EPS completion of the $43B Seagen acquisition (which we deem low probability), Pfizer
guidance shared earlier in October. We continue to see the large $43B Seagen reconfirmed its expectation for the transaction close by Q4 2023 or early 2024,
acquisition as the next major near-term catalyst. The company received emphasizing continued collaboration with U.S. and EU regulators. / Sel Hardy
unconditional European Commission antitrust clearance on October 19 and
management expects a successful transaction close in late 2023/early 2024. / Sel May 02, 2023
Hardy 11:52 AM ET... CFRA Retains Buy Opinion on Shares of Pfizer Inc. (PFE 38.85****):
We lower our target price by $4 to $48, 11.7x our 2024 EPS, below PFE’s 10-year
October 16, 2023 historical forward P/E average. We lift our 2023 EPS estimate by $0.25 to $3.65 and
02:01 PM ET... CFRA Keeps Buy Opinion on Shares of Pfizer Inc. (PFE 33.52****): keep our 2024 EPS at $4.12. Pfizer posts Q1 EPS of $1.23 vs. $1.62 (-24% Y/Y)
We lower our target by $3 to $40, 11.3x our 2024 EPS, below PFE’s 10-year primarily due to lower Y/Y Covid-19 vaccine revenues compared to very strong Q1
historical forward P/E average. We lower our 2023 EPS view by $1.80 to $1.67 and 2022 sales. Yet, Q1 EPS was $0.28 above our estimate and $0.24 consensus as R&D
lower our 2024 EPS estimate by $0.25 to $3.53. Pfizer cut its 2023 revenue and EPS cost increases (+9% Y/Y) were below expectations. Q1 revenues of $18.3B (-29% Y/
guidance for the remainder of 2023, and we are revising our model to take into Y), beat consensus estimates by an eye-catching $1.8B, as sales of $3.1B from the
account the newly shared information regarding Covid-19-related products sales Covid-19 vaccine (Cominatry) were higher than expected despite a sharp Y/Y decline
expectations for the rest of 2023. The main reason for the revision comes from an (-77% Y/Y), combined with strong sales of $4.1B from the antiviral Paxlovid. We
estimated 7.9M Paxlovid return by the U.S. government from the Emergency Use continue to think PFE is attractive at current valuations. We expect the ex-Covid
Authorization Use authorized inventory, which is expected to result in a $4.2B sales growth to pick up in the second half of the year thanks to a number of large
revenue reversal this year. The company is also taking into account lower new product launches, while the Seagen acquisition, once approved, will have a
expectations for the Covid-19 vaccine sales for the remainder of the year and a strong contribution to oncology sales. / Sel Hardy
delay in the commercialization of Paxlovid. We maintain our long-term positive
outlook on shares of PFE, yet now forecast the company to record $60.3B in total March 13, 2023
revenue in 2023 versus $67.8B. / Sel Hardy 11:07 AM ET... CFRA Keeps Buy Opinion on Shares of Pfizer Inc. (PFE 40.09****):
PFE agrees to buy biopharma Seagen (SGEN 201 ***) for $229/share in cash, an
September 11, 2023 enterprise value of $43B. We estimate the deal at 12.9x EV to projected ‘24
03:28 PM ET... CFRA Retains Buy Opinion on Shares of Pfizer Inc. (PFE 34.06****): revenues, about 3% above SGEN’s historical forward average. PFE expects to close
In line with expectations, today the FDA approved the upgraded mRNA vaccine by early 2024, but this is dependent on both shareholder and regulatory approval.
against Covid-19 from Pfizer and Moderna targeting the new omicron variant Given that SGEN is trading at about a 13% discount to the deal price, we think the
XBB.1.5. The speed of the approval was as anticipated, as Covid-19 cases and market is pricing in some concern over antitrust hurdles. The combination adds to
hospitalizations have been rapidly rising in recent weeks. Next, the CDC will PFE’s core oncology area ($12B in revenues in 2022, versus SGEN’s $2B), but also
recommend who is eligible to receive the shots, which is expected to take place brings in a potential $10B in sales by 2030. If approved, the deal goes a long way
during the advisory panel meeting tomorrow. We consider the news positive for both towards replacing about $17B in revenues that PFE has projected to be at risk
Pfizer and Moderna (MRNA 106 ****). Pfizer expects to generate $13.5B in Covid- between 2025 and 2030 following patent expirations. PFE plans to fund the deal
19 vaccine sales this year and, per CEO A. Bourla, the updated vaccine is expected to with about $31B in new long-term debt, the remainder from available liquidity. If
be available in the next days, pending CDC recommendations. MRNA stated earlier approved, the deal nearly doubles PFE’s long-term debt (to $64B from current
that the company is ready to start delivering doses in September and expects $6B- $33B), but only about $4.2B matures through 2025. / Stewart Glickman, CFA
$8B from vaccine sales in 2023. We keep our target for PFE at $43, 11.4x our 2024
EPS, below PFE’s 10-year historical forward P/E average. We raise our 2023 EPS
view by $0.03 to $3.47 and maintain our 2024 EPS estimate at $3.78. / Sel Hardy
Note: Research notes reflect CFRA's published opinions and analysis on the stock at the time the note was published. The note reflects the views of the equity analyst as of
the date and time indicated in the note, and may not reflect CFRA's current view on the company.
Redistribution or reproduction is prohibited without prior written permission. Copyright © 2023 CFRA. 5
Stock Report | October 30, 2023 | NYSE Symbol: PFE | PFE is in the S&P 500
Pfizer Inc.
Analysts Recommendations Wall Street Consensus Opinion
Buy/Hold
For fiscal year 2023, analysts estimate that PFE will earn
USD 1.59. For fiscal year 2024, analysts estimate that PFE's
earnings per share will grow by 102.43% to USD 3.21.
No. of
Recommendations % of Total 1 Mo.Prior 3 Mos.Prior
Buy 9 36 7 8
Buy/Hold 2 8 3 3
Hold 14 56 15 15
Weak hold 0 0 0 0
Sell 0 0 0 0
No Opinion 0 0 0 0
Total 25 100 25 26
Fiscal Year Avg Est. High Est. Low Est. # of Est. Est. P/E
2024 3.21 3.75 2.36 20 9.38
2023 1.59 1.65 1.45 15 18.99
2024 vs. 2023 p 102% p 127% p 63% p 33% q -51%
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Stock Report | October 30, 2023 | NYSE Symbol: PFE | PFE is in the S&P 500
Pfizer Inc.
Glossary
Redistribution or reproduction is prohibited without prior written permission. Copyright © 2023 CFRA. 7
Stock Report | October 30, 2023 | NYSE Symbol: PFE | PFE is in the S&P 500
Pfizer Inc.
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