NISHCHAY Batch Aldehyde and ketones LECTURE-2

④ Oxidation dials : (vincinal dids):

of
Idiol) : -

i or Ho -

--i
-
or

-
↓(0]

or c =0 -

(aem dial)
is Oxidation acid) :
with HIOh (periodic
-

OH HIO4
k
-

-8
- 0
7c 0
= = -

-
OH

113 CH3 G

H- OH H-
↓- on - ->
O
CH3-k-4 .

-on HIOh
-
In
HO H
0H
O

- olf
I -

->
H20 nek-on
H
-

HO -
c -
H

↓
C3 OH
I
-or-5
-

H20 * -H
U13
-

H
a

:i HI04
>

=
?

CgOH

(ii) LTA (head tetra autate). -

BuC(N(n- P6
+2

works same as HIO4-

OH LTA
(c 7 0
=
- =
0 +

->

- H

Ammonium nitrate) :-
from
3
CAN (Ceric

(N : (No16-ct3

I + c
=
0 -

=
0

HI04 A

>↳7 LTA
a(2[) = 0

CAN
 oxidation ketones.
of
-

① Oxidation -
Bayer Villige
O

Y I MCPBA
R-- o -
R
R- -

R ->
ester
peracid
Mi
-
-
one
P-00 R- H &
O H -

R "-
-

Il
R-c -

R -- -
C

&
o -
o -
R
is
% R-C
↓
-
II
R
?
2
R I
R
- c -
0
-
↳

↓ ↓ R
-
o
-

3
⑧
Il
R -c -
o
-
R
⑧
⑧

CHI-K-CHS E
Il
113-0
-
c -

13
O
0
Il
Il

[] d 59
0
↑

Y peracid >
E
-
 -* -Cag
O
m(PBA
->
Cz
-- 0C15

113

C
-- us -
MCPBA
az--or k -
CH3

↳3 ↳
⑧

a-c-pr- m(PBA
CHz--o-Ph .

-meA
O
Il

->
II-
order
Migratory Aptitude ; 2"-3
feralkyl group
u - -
-

Ph
C-4-457-CHGy7-C3 -

is
↑
CoH5 -k-
⑧
/413 MCPBA
-- Ph-o- - a 43 -
- 3
s
ot
1413
pn-k-o-ch -
13
0 0
11 mCPBA
R-C -
H -
R--on
peracid
↓

oxidising agent
* Rule :
Popoff's
-

* 0

My--on
⑧
Il
My-- +H-c-

⑧
O
kMno/n
Il
CHz-c-CH2-CH3 A
>
Ca-- on
*
+ C3-coon
A
 sfect
Heating of dicaboxylic
* acids -

I
COM n =
0 - oxalic acid
-
O

[czln 1 Malonic aud

S
n
=
->
-

succinic acid
brow n =
2 +

n
=

3 -
Elutaric
-
and
4 +
acid
n
Adipic A
=

n
=

5 -
Pimlic aid P
-

CON A CO2 4 + 204 +

H20
-

door ↓
Burns with blue
flame
-

oxalalic and

CWH

CZCOH +C024
D
12 ->

In
malonic ad

-COH cn

[T-con -
] +
cont

--
-
or
+ H20

Succinic
anhydride
succinic and
 [I0
-
jate
[0
pathalic and
pathatic anhydride
.

0
11

[]
is
-
5. Enex

i
H
CWH
-
c ->
A

-con maleic
anhydride
.

maleic aid

COl
Ra - X -

now - H
 ⑧
II
COOM

I0
A

ils -

In

COOH

itzly
-> D
↑
CO2 +H2O

cost
COM
I
- -
[7
CO2 +120
↑

karn

↳ ⑧
->
A
X due
sing
currents
of
sing
Benzene
Got
Temphthalic acid
O

CON

knals -o I ↑

202
+

H20

corn
 effect B-ketoacids'-
Heating of
*

----on 11

B
-m
&
- -+ cort
P

:
- -z
-3
↳ Ed
->
0

· Lenal)
=

2
·

I
Itautomerism

C3-ge
⑧

8 N - cha-K-On -
A
C15NO2 +CO24
- I

effect <-position greater

the at
greater
-I

decarboxylation
will be the late
of
.

-cat-
COM Il
cot H
100 y/c
2 2
2
[
-B
2002
S
+
D

2202
-
↓

+c
* heateda
Bypaling vapours of calboxylic and over

R-I-on A
3N°
R-K-R
O

RYON+R--on zie
MnO "-R
Ric ⑧
+RYR
+ R - R

R-4P-on+ H-k-on ino

-> R-IR+ R-I-H
30° M
n
4
+
-
- .

⑰
Healing effect of calcium or Balium salt
of calling
a

(RP-ogla = R-I-R CaCO3

-
+

(R- 4-oBa BaCOs+R-K-R .

& i-o- I)-- E

⑭
processi -dicobalt ocla
carbony
-

CO2078
R-CH
=

U2 >
RCHECHECHO
+

[0H2
↓
water
gas
④ Wacker process ! -

Palle Calla it
R c -
4
R-GH= CH2
-
7

02 Bubble
i DMF/120
60-70°