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Dfgjukl
Dfgjukl
body by the blood–brain barrier. Lymph from the meningeal lymphatic vessels in the
CNS drains to the deep cervical lymph nodes.[7]
Size
Upper limit of lymph node sizes in adults
Generally 10 mm[8][9]
Inguinal 10[10] – 20 mm[11]
Pelvis 10 mm for ovoid lymph nodes, 8 mm for rounded[10]
Neck
Generally (non-retropharyngeal) 10 mm[10][12]
Jugulodigastric lymph nodes 11mm[10] or 15 mm[12]
Retropharyngeal 8 mm[12]
Lateral retropharyngeal: 5 mm[10]
Mediastinum
Mediastinum, generally 10 mm[10]
Superior mediastinum and high paratracheal 7mm[13]
Low paratracheal and subcarinal 11 mm[13]
Upper abdominal
Retrocrural space 6 mm[14]
Paracardiac 8 mm[14]
Gastrohepatic ligament 8 mm[14]
Upper paraaortic region 9 mm[14]
Portacaval space 10 mm[14]
Porta hepatis 7 mm[14]
Lower paraaortic region 11 mm[14]
Subdivisions
Histology of a normal lymphoid follicle, showing dark, light, mantle and marginal
zones
A lymph node is divided into compartments called nodules (or lobules), each
consisting of a region of cortex with combined follicle B cells, a paracortex of T
cells, and a part of the nodule in the medulla.[15] The substance of a lymph node
is divided into the outer cortex and the inner medulla.[3] The cortex of a lymph
node is the outer portion of the node, underneath the capsule and the subcapsular
sinus.[15] It has an outer part and a deeper part known as the paracortex.[15] The
outer cortex consists of groups of mainly inactivated B cells called follicles.[4]
When activated, these may develop into what is called a germinal centre.[4] The
deeper paracortex mainly consists of the T cells.[4] Here the T-cells mainly
interact with dendritic cells, and the reticular network is dense.[16]
The medulla contains large blood vessels, sinuses and medullary cords that contain
antibody-secreting plasma cells. There are fewer cells in the medulla.[4]
The medullary cords are cords of lymphatic tissue, and include plasm