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AIATS-02-(OYM + CF)-Q.104 (4) Fusion of abnormal egg (23 + X) and
Topic: Principles of Inheritance and Variation: normal sperm (22 + Y)
Genetic Disorders 4. A person inflicted with Down’s syndrome has
Number of autosomes in the somatic cell of an total 45 autosomal chromosomes in the somatic
individual inflicted with Down’s syndrome would cell. What will be the number of autosomes in
be the normal individual?
(1) 47 (2) 43 (1) 47
(2) 46
(3) 46 (4) 45
(3) 45
(4) 44

AIATS-02-(OYM + CF)-Q.116
Topic: Principles of Inheritance and Variation:
Genetic Disorders
Consider the following pedigree chart.
[Here, shaded symbols are for those individuals
who express the trait]
Practice Questions:
1. Down’s syndrome occurs due to
(1) Trisomy of chromosome number 21
(2) Trisomy of X-chromosome
(3) Trisomy of Y-chromosome
(4) Monosomy of chromosome number 21
2. Number of autosomes in somatic cell of a
normal individual is 44. What will be the number
Which of the following statements cannot be
of autosomes if a person is suffering from
disorder due to trisomy of chromosome number true for this pedigree?
20 and monosomy of chromosome number 10? (1) The trait considered here can be X-linked
(1) 45 (2) Both the parents (P) are carrier for the trait
(2) 44 (3) The probability of F1(A) for carrying the
(3) 47 allele of that particular trait is 100%
(4) 46 (4) The trait studied here is Y-linked
3. In human, a disorder ‘P’ develops due to trisomy
of chromosome. Such condition can arise due
to all of the following, except
(1) Fusion of normal (n) male and female (n)
gametes
(2) Fusion of normal egg (22 + X) and abnormal
sperm (22 + XY)
(3) Fusion of normal sperm (22 + Y) and
abnormal egg (22 + XX)

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Practice Questions: dominant trait

1. Mark the incorrect statement w.r.t. human
beings. AIATS-02-(OYM + CF)-Q.105
Topic: Principles of Inheritance and Variation:
(1) A mother transmits an allele of X-linked
Inheritance of One Gene
genes to daughters only In the Mendelian monohybrid cross, what
(2) For an X-linked recessive trait, a single percent of individuals in F2 generation receives
recessive allele is sufficient to make a male the recessive allele?
affected with the disorder (1) 12.5% (2) 50%
(3) A father transmits his allele of X-linked (3) 25% (4) 75%

genes to daughters only

(4) An individual even with a single dominant
allele will always show the dominant trait
2. An unaffected individual w.r.t. given pedigree
can be a carrier of A gene. Here, A is

Practice Questions:
1. In the Mendelian monohybrid cross, what
percent of individuals in F2 generation receives
only recessive alleles?
(1) 12.5% (2) 25%

(1) X-linked recessive (3) 50% (4) 75%

2. In the Mendelian monohybrid cross, what
(2) Y-linked percent of individuals in F2 generation receives
only dominant alleles?
(3) X-linked dominant
(1) 12.5%
(4) Autosomal dominant
(2) 25%
3. A Y-linked trait is always passed from (3) 50%
(1) Father to daughter (4) 75%
3. In the Mendelian monohybrid cross, what
(2) Mother to daughter
percent of individuals in F2 generation receives
(3) Father to son the dominant allele?
(1) 12.5%
(4) Grandmother to grandson
(2) 50%
4.
(3) 25%
(4) 75%
4. In the Mendelian monohybrid cross, what
percent of individuals in F2 generation receives
both dominant and recessive alleles?
(1) 12.5%
(2) 50%
Consider the above pedigree and mark the
correct statement. (3) 75%
(4) 25%
(1) It represents inheritance of Y-linked trait
(2) It cannot be Y-linked trait as daughter is also
AIATS-02-(OYM + CF)-Q.110
affected Topic: Principles of Inheritance and Variation:
Inheritance of Two Genes
(3) It cannot represent inheritance of autosomal
In the Mendelian dihybrid cross for seed colour
dominant trait and seed shape 2400 seeds are obtained in F 2
generation, how many seeds would be hybrid
(4) Carriers are unaffected in autosomal
yellow?

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(1) 1800 Practice Questions:

(2) 1200 1. A translation unit in mRNA is the sequence of
RNA
(3) 300
(1) That contains start codon but not stop
(4) 600
codon
(2) That codes for a polypeptide which is not
required in the cell
(3) Which is flanked by start codon at 5’ end
and stop codon at 3’ end and codes for a
polypeptide
(4) That is transcribed but not translated
2. Which of the following is a translation unit?
Practice Questions: (1) 5’ AUG UUU UGG AGC AUG – 3’

1. In a typical Mendelian monohybrid cross for (2) 5’ AUG UUU UGU AUG UUU – 3’
seed colour in pea, what percent of seed would (3) 5’ GUA UUU UGA AUG AUG – 3’
be hybrid yellow in F2 generation?
(4) 5’ AUG UUU UUA AUG UAA – 3’
(1) 100% (2) 25%
3. Which of the following translation unit
(3) 50% (4) 75% synthesizes the polypeptide with maximum
number of amino acids?
2. In dihybrid cross performed by the Mendel, what
is the probability of hybrid yellow seeds in F2 (1) 5’ – AUG UUU UGA AGC UAA – 3’
generation? (2) 5’ – AUG UGA UUU AGC UAA – 3’
3
(1)
4
(3) 5’ – AUG UUU AGC AAG UAA – 3’
1 (4) 5’ – AUG UAA AGC AAG UAA – 3’
(2)
2
4. All of the following are some additional
1
(3) sequences in mRNA that are not translated,
4
except
1
(4) (1) Untranslated regions
8

3. In Mendelian monohybrid cross, what is the (2) Introns

genotypic ratio of the offspring obtained in F 2
(3) Stop codon
generation?
(4) Exons
(1) 3:1 (2) 9:3:3:1
(3) 1:2:1 (4) 1:2:1:2:4:2:1:2:1
AIATS 02 –(OYM + CF) – Q.133

AIATS 02 –(OYM+CF) – Q.135 Topic: Molecular Basis of Inheritance:

Transcription
Topic: Molecular Basis of Inheritance: The DNA sequence that is defined as gene,
Translation
codes
Which of the following is a translation unit in
mRNA that synthesizes the polypeptide with (1) Only for a polypeptide
maximum number of amino acids? (2) For hnRNA but not for other RNAs
(1) 5 – AUG UUU UGA AGC AUG – 3 (3) Only for mRNA
(2) 3 – AUG UCG AGC UGA GUG – 5 (4) For mRNA, tRNA or rRNA
(3) 5 – AUG AAG GAU UAG UAA – 3
(4) 3 – AGU AUU UCA ACG GUA – 5

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Practice Questions: 2. An hnRNA after post-transcriptional

1. A gene can code for modification contains
(A) Polypeptide (1) Only introns
(B) hnRNA (2) Exons
(C) mRNA (3) Both introns and exons
(D) tRNA (4) Neither introns nor exons
(E) rRNA 3. A polypeptide is a polymer of A and is
The correct ones are synthesized by the process of B .
(1) Only C, D & E Here A and B, respectively are
(2) Only B, C, D & E (1) Amino acids and transcription
(3) Only A & B (2) Amino acids and translation
(4) All A, B, C, D & E (3) Nucleotides and transcription
(4) Nucleotides and replication

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Answer Key

AIATS-02-(OYM + CF)-Q.104 AIATS-02-(OYM + CF)-Q.110

Topic: Principles of Inheritance and Variation: Topic: Principles of Inheritance and Variation:
Genetic Disorders Inheritance of Two Genes
1. (1) 1. (3)
2. (2) 2. (2)
3. (1) 3. (3)
4. (4) AIATS 02 –(OYM + CF) – Q.135
AIATS-02-(OYM + CF)-Q.116 Topic: Molecular Basis of Inheritance:
Topic: Principles of Inheritance and Variation: Translation
Genetic Disorders
1. (3)
1. (1)
2. (4)
2. (1)
3. (3)
3. (3)
4. (4)
4. (2)
AIATS 02 –(OYM + CF) – Q.133
AIATS-02-(OYM + CF)-Q.105
Topic: Principles of Inheritance and Variation: Topic: Molecular Basis of Inheritance:
Inheritance of One Gene Transcription

1. (2) 1. (4)
2. (2) 2. (2)
3. (4) 3. (2)
4. (2)

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