Stephanie,

Great post. If melanoma spreads, it will usually begin spreading through channels in the

skin (lymphatics) to the nearest group of glands (lymph nodes). Lymph nodes are part of the

body's immune system. They help remove unwanted bacteria and particles from the body and

play a role in activating the immune system (Davis et al., 2019). A diagnosis of melanoma will

usually begin with an examination of the skin. Sometimes, GPs take digital photographs of a

suspected tumor so they can email them to a specialist for assessment. As melanoma is a

relatively rare condition, many GPs will only see a case every few years. It's important for the

patient to monitor their moles and return to the GP if they notice any changes. Taking photos to

document any changes will help with diagnosis.

Reference

Davis, L. E., Shalin, S. C., & Tackett, A. J. (2019). Current state of melanoma diagnosis and

treatment. Cancer Biology & Therapy, 20(11), 1366-1379.

https://doi.org/10.1080/15384047.2019.1640032

Stacey,

Thank you for this great piece of information. Chlamydial infection is the most common

sexually transmitted bacterial infection in the United States. It is thought that another million

cases of chlamydia remain unreported. Chlamydia is often insidious and asymptomatic. In

women, genital chlamydial infection may result in urethritis, cervicitis, pelvic inflammatory

disease (PID), infertility, ectopic pregnancy, and chronic pelvic pain (O’Connor et al., 2022).

Chlamydial infection during pregnancy is related to adverse pregnancy outcomes including

miscarriage, premature rupture of membranes, preterm labor, low birth weight, and infant
mortality. There is direct evidence that screening reduces complications of chlamydial infection

in women who are at increased risk, with a moderate magnitude of benefit. Such complications

include pelvic inflammatory disease, infertility, and premature delivery (O’Connor et al., 2022).

Reference

O’Connor, N. P., Burke, P. C., Worley, S., Kadkhoda, K., Goje, O., & Foster, C. B. (2022).

Outcomes After Positive Syphilis Screening. Pediatrics, 150(3).

https://doi.org/10.1542/peds.2022-056457

Hello Melissa,

You have comprehensively described the characteristics of papulosquamous eruptions in

children. I want to add that Papulosquamous disorders are skin lesions consisting of red or purple

papules or plaques with scales. These constitute a common group among the wide spectrum of

skin diseases in children (Gandhi et al., 2022). In children, they may be due to genetic factors,

viral or bacterial infections, or have an autoimmune etiology. These disorders have acute to

chronic patterns, persisting from weeks to months, and sometimes up to years. The spectrum

varies from inflammatory diseases like psoriasis that have a relapsing-remitting pattern to self-

limiting diseases like pityriasis rosea to treatment-resistant diseases as parapsoriasis (Gandhi et

al., 2022). Papulosquamous disorders account for a large number of the overall dermatoses,

belonging to both the adult and pediatric populations.

Reference
Gandhi, J., Agrawal, S., Gupta, S., Verma, K., & Mohite, A. (2022). Pattern of Papulosquamous

Disorders in Children: A Clinico-Epidemiological Study. Cureus, 14(1).

https://doi.org/10.7759/cureus.21194