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Abstract
In this paper, the concept, fabrication, activation and testing of a novel synchronous micropump
based on microfabricated copper coils and polymer magnets are presented. The pump works
by the synchronized rotation of two polymer magnets in an annular SU-8 microfluidic channel.
Magnet rotation is achieved by sequentially activating a set of planar coils to repel or attract
the first magnet (traveling magnet) through the channel, while the second one is anchored
between the inlet and the outlet ports. At the end of each pumping cycle, the magnets exchange
their anchored and traveling functions. The synchronization of magnet rotation has been
achieved through programming two activation schemes that proved the high dependence of the
pump operation and performance on employed activation scheme parameters. The magnetic
forces exerted from electroplated coils on the polymer magnet were tested experimentally
using a three-dimensional force sensor. Different coil dimensions have been investigated. A
maximum force of 658 μN at an applied current of 138 mA was achieved. The micropump has
successfully pumped water with rotational speeds up to 83.33 rpm. Water flow rates in the
range of 17.3 μL min−1 at 31.25 rpm to 158.7 μL min−1 at 83.33 rpm were achieved.
(Some figures may appear in colour only in the online journal)
0960-1317/12/065027+08$33.00 1 © 2012 IOP Publishing Ltd Printed in the UK & the USA
J. Micromech. Microeng. 22 (2012) 065027 A T Al Halhouli et al
Figure 2. Pumping cycle and switching sequence for the synchronous micropump [12].
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J. Micromech. Microeng. 22 (2012) 065027 A T Al Halhouli et al
Figure 3. A microfabricated EMMP with SU-8 channel, and double 3.1. Chamber chip
layer electroplated copper coils.
The pump chamber chip consists of an SU-8 fluidic channel,
clockwise from the anchoring position and past the channel and double layer electroplated copper coils. The fluidic
inlet (figure 2(c)). At the same time the moving magnet channel includes inlet and outlet channels of 813 μm height
is attracted toward the anchoring position (figure 2(a)). The and inner and outer diameters of 5550 μm, and 8550 μm,
successive activation for the new traveling magnet and the respectively. The copper coils have two layers that contain
exchange of roles will be continually repeated and a pumping 35 turns/layer (figure 3).
action obtained. The pump chamber fabrication process begins with the
lower conductors of the double-layer coil (see figure 4, left).
After depositing a seed layer of 10 nm Cr and 275 nm Cu
3. Fabrication and optimization
onto the ceramic substrate in an LS440 sputtering machine
The final EMMP comprised a pump chamber chip, a (Von Ardenne Anlagentechnik GmbH), a mold of AZ9260 is
glass cover and two polymer magnets (see figure 3). The patterned and filled with a 13–15 μm thick copper layer by
fabrication processes and dimensions of pump components electroplating. (i) After stripping the AZ9260 mold, an SU-8
are summarized in the following sections. layer is spun onto these structures as insulation. This layer
The polymer magnet molds and the fluidic channels were provides openings for through connections to the upper coil
patterned using EPON SU-8 (from Shell Chemical). SU-8 is layer. (ii) Both connections and upper conductors are likewise
a thick, epoxy-photo-plastic, high-aspect ratio UV-sensitive structured by AZ9260 molding and copper electroplating.
negative resist. It can be spin coated in a conventional spinner After that, a second SU-8 layer serves both as insulation
in thicknesses ranging from 1 to 300 μm. Up to 2 mm between upper conductors and rotating magnets and as a
thickness can be obtained with multilayer coatings. Due to bearing layer for the rotor. (iii) Finally, the circular pump
its chemical stability and favorable mechanical and optical channels are patterned with thick SU-8 layer. (iv) An example
properties, it has been used successfully in MEMS fabrication of a fabricated chamber is shown in figure 4 (right).
(i)
(ii)
(iii)
(iv)
(a) (b)
Figure 4. (a) Pump chamber fabrication process plan, and (b) resulting chamber.
3
J. Micromech. Microeng. 22 (2012) 065027 A T Al Halhouli et al
(i)
(ii)
(iii)
(iv)
(v)
(a) (b)
Figure 5. (a) Polymer magnet fabrication process plan, and (b) resulting magnets.
product. -450
The mold is fabricated (figure 5(a)) by first electroplating -600
a 2 μm sacrificial copper layer onto a ceramic substrate Field strength [kA/m]
(figure 5(a)) (i). A 50 μm SU-8 layer which serves as a base
Figure 6. Magnetization curve of a microfabricated polymer
plate is then patterned (ii). After that, a thick SU-8 layer is spun magnet.
on and structured to provide a filling form for the polymer
magnet (iii). The viscous polymer magnet is then inserted
The functional capability of the magnets is another
into the mold and baked out (iv). After baking, a polishing
dominant parameter. The tests have been conducted after
process follows to level the compound structure and to remove
mounting several polymer magnets with different tolerances
waste residue. By etching the sacrificial layer the magnets are
and lengths into the pump channels and running them with
detached from the substrate (v). Samples of fabricated polymer or without glass cover. Such tests have the main objective of
magnets with different shapes are shown in figure 5(b). stable magnet rotation in the channel (low friction) for a wide
Applying this method allows the fabrication of magnets range of rotational speeds.
with arbitrary shape and properties, ensuring complete Tests were extensively performed in a channel of 1500 μm
compatibility with existing process chains. Fabricated width and 813 μm height. Tolerances between magnet and
polymer magnets are then axially magnetized using special channel walls were between 50 μm and 150 μm and
magnetization equipment [19]. magnet lengths were considered as a function of coil length:
1 × length, 1.25 × length, 1.5 × length and 2 × length.
3.3. Polymer magnets and coil characterization Results showed that an optimal tolerance is in the range of 50–
60 μm and that the 1.5 × length magnet provides the most
In order to examine the magnetic flux density of stable and smooth travel.
microfabricated polymer magnets, their magnetization curve Lastly, the magnetic force generated from a electroplated
has been experimentally plotted using a vibrating sample copper coil on a polymer magnet has been measured. Since the
magnetometer (LakeShore Inc.). A total of 90% wt powder coil fabrication area available on the chip is limited, different
ratio at a structure height of 389 μm has been used. geometrical design parameters (wire width, gap between
The hysteresis curve (figure 6) shows that the simultaneous turns (g) and different number of turns (n) see
microfabricated magnets retain stronger residual magnetic table 2) that maximize the theoretical magnetic field intensity
flux density of 342 mT than previously published data [11]. within the required area were fabricated. Such parameters
Strong residual magnetic flux density is essential to obtain were selected according to a previously published study that
enough repel/attracting magnetic force required for successful estimates for the magnetic field intensity in such slightly
pumping action. curved microcoils [17].
4
J. Micromech. Microeng. 22 (2012) 065027 A T Al Halhouli et al
5
J. Micromech. Microeng. 22 (2012) 065027 A T Al Halhouli et al
Figure 9. Coil labels used in the activation scheme. (Left) 8-coil chip and labels and (right) 12-coil chip and labels.
5.2. Flow rate and volumetric efficiency Figure 10. Flow rate at various rotational speeds in the EMMP.
The flow performance in the pump is influenced by its
geometrical parameters: channel height, width and radii and its
activation parameters: activation time step and driving voltage.
The activation time step determines the pump rotational speed
and the magnetic flux overcomes the friction and inertia
forces to move the traveling magnet along the channel.
The pump rotational speed is proportional to the driving
voltage (magnetic flux), which should be adjusted to employ
simultaneous attraction/repulsion force on the magnet.
The pump was run for rotational speeds up to 83.33 rpm.
Successful flow rates in the range of 17.3 μL min−1 at 31 rpm
to 158.7 μL min−1 at 83.33 rpm were achieved (figure 10).
The flow rate shows a linear relationship with the
rotational speed above 30 rpm. Below this value, no flow
was observed. This is due to the internal leak of the working
fluid through the gap between the traveling parts and the chip Figure 11. Schematic of the pumping cycle phases.
channel’s surface. This leak shows nonlinear behavior with the
rotational speed, since the amount of working fluid flowing in where QT is the theoretical volumetric flow rate (μL min−1),
the gap depends on the activation time step given that the Vd is the fluid displaced volume per magnet revolution
pressure drop across the pump ports is constant. (μL revolution−1), and ωp is the pump rotational speed (rpm).
To estimate the pump performance, the volumetric The fluid displaced volume (Vd ) is a critical value for the
efficiency is considered and therefore the theoretical calculation of QT . It depends on the timing of when magnets
volumetric flow rate, QT, should be estimated. QT assumes no exchange their function between anchoring and moving. To
leakage and is simply the result of the fluid displaced volume clarify the calculation of this parameter, a schematic of the
(Vd) multiplied by pump rotational speed (ωp): pump activation concept considered in this work is shown in
QT = Vd ∗ ωp (1) figure 11.
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J. Micromech. Microeng. 22 (2012) 065027 A T Al Halhouli et al
The pumping cycle has two phases. The first phase is the
pumping phase and it begins when the traveling magnet (MT)
is located at coil 5 and the anchoring magnet (MA) is set at
coil 1 (figure 11, left). During this phase the MT moves in steps
from coil 5 to coil 9 while MA is stationary (figure 11, right).
The second phase is the switching phase. During this phase,
the two magnets exchange their function between anchoring
and traveling. The traveling magnet moves from coil 9 to coil
1 and stops there (becomes anchored), while the anchored one
moves toward coil 5 and becomes the traveling magnet which
is the same situation as in figure 11, left.
The displaced volume per revolution Vd can be calculated
from the volume of the fluid displaced by the magnet piston MT
as it rotates between coil 5 and coil 9. Referring to figure 11,
Vd is given by
θ Figure 12. The pump volumetric efficiency as a function of its
Vd = ro2 − ri2 h (2) rotational speed.
2
where ro and ri are, respectively, the outer and inner radii
of the flow channel, h is its height and θ is the included the pump speed is explained with equation (1). The internal
angle in radians between the leading edges of MT in the two leakage decreases at high speed.
locations. For a flow channel with ro = 4275 μm, ri = 2775 μm, In comparison with other pumping concepts, achieved
h = 813 μm, θ = 23 π , Vd was found to be 9.0 μL. flow rates proved to be comparative (see table 4). For
The volumetric efficiency, ηv , is an important performance more information, a comprehensive overview of major
parameter that describes the amount of leakage or losses in issues, working principles and performance parameters of
macroscale positive displacement pump. It refers to the ratio micropumps for biomedical applications has been recently
of actual volumetric flow rate to that obtained without leakage, presented in [20].
and is defined as An important observation that has been noticed during
QA testing is that the moving magnet pushes the small bubbles
ηv = (3) entering the pump chamber through the fluidic channel without
QT
any problems. This opens the way to a near-future study on
where QA is the actual (experimental) volumetric flow rate (μL
the pump capability for working as self-priming and bubble
min−1). Table 3 lists the flow rates, the volumetric efficiency
tolerance.
and the calculated pump pressure head. Figure 12 shows the
volumetric efficiency as a function of the pump speed.
The shape of the plot shown in figure 12 is typical for 6. Conclusions
macroscale positive displacement pumps and indicates the
internal leakage effect. At low speed the internal leakage is The paper introduced the concept, fabrication, activation
high and becomes dominant, while the theoretical flow out of and testing of a novel synchronous micropump based on
the pump is low. The dependence of the theoretical flow on microfabricated copper coils and polymer magnets. The pump
7
J. Micromech. Microeng. 22 (2012) 065027 A T Al Halhouli et al
works by the synchronized rotation of two polymer magnets [4] Rhie W and Higuchi T 2010 Design and fabrication of
in an annular microfluidic channel. An 8-coil model and a a screw-driven multi-channel peristaltic pump for
portable microfluidic devices J. Micromech. Microeng.
12-coil model were fabricated and tested in this work. EPON
20 085036
SU-8 was used for patterning the polymer magnet molds and [5] Woias P 2005 Micropumps—past, progress and future
the fluidic channels. The permanent magnets are realized by prospects Sensors Actuators B 105 28–38
embedding a viscous polymer magnet in a microfabricated [6] Al-Halhouli A T 2009 Recent advances in on-disk viscous
SU-8 mold. The mold is fabricated onto a 2 μm sacrificial micropumps J. Microelectron. Electron. Packag. 6 240–9
[7] Hatch A, Kamholz A E, Holman G, Yager P
copper layer electroplated onto a ceramic substrate.
and Böhringer K F 2001 A ferrofluidic magnetic
The forces generated from the coils on the microfabricated micropump J. Microelectromech. Syst. 10 215–21
polymer magnet were tested using a three-axis force sensor [8] Nguyen N T and Chai M F 2009 A stepper micropump for
and were found to vary almost linearly with applied current. ferrofluid driven microfluidic systems Micro Nanosystems
A maximum force of 658 μN was achieved at 138 mA. 1 17–21
[9] Al-Halhouli A T, Kilani M I and Büttgenbach S 2010
A number of activation schemes were tested using the 8
Development of a novel electromagnetic pump for
and 12 planar electroplated coils chips. The best scheme for bio-medical applications Sensors Actuators A 162 172–6
exciting the 8-coil chip was found to be the generation of an [10] Lorenz H, Despont M, Fahrni N, Brugger J, Vettiger P
attractive magnetic force in the holding coils and on one of and Renaud P 1998 High-aspect-ratio, ultrathick,
the activation coils while the rest of coils repel. As for the negative-tone near-UVB photoresist and its application for
MEMS Sensors Actuators A 64 33–9
12-coil chip, best results were achieved when the anchored
[11] Büttgenbach S, Burisch A and Hesselbach J 2011 Design and
magnet is attracted by applying on attractive force on the Manufacturing of Active Microsystems (Berlin: Springer)
holding coils and is repelled from the two neighboring front [12] Al-Halhouli A T and Büttgenbach S 2010 Numerical analysis
and back coils (C2, C11). This combination of forces employs of mixing in a multifunction electromagnetic micropump
enough holding force against the pumped fluid and squeezes it ICNMM 2010 (Montreal, Canada) FEDSM-
ICNMM2010-30971
between the inlet and outlet ports. The coils (C2–C11) create
[13] Lorenz H, Despont M, Fahrni N, Brugger J, Vettiger P
a simultaneous moving magnetic field on the traveling magnet and Renaud P 1998 High-aspect ratio, ultrathick,
to create pumping action on the fluid. It has been found that at negative-tone near-UV photoresist and its applications for
least two separating coils before switching are required in order MEMS Sensors Actuators A 64 33–9
to avoid uncontrolled movement (slipping) of the anchored [14] Conradie E H and Moore D F 2002 SU-8 thick photoresist
processing as a functional material for MEMS applications
or traveling magnets due to the repelling forces between the
J. Micromech. Microeng. 12 368–74
magnets themselves. [15] Al-Halhouli A T, Kampen I, Krah T and Büttgenbach S 2008
The pump was run for rotational speeds up to 83.33 rpm. Nanoindentation testing of SU-8 photoresist mechanical
Successful flow rates in the range of 17.3 μL min−1 at 31 rpm properties Microelectron. Eng. 85 942–4
to 158.7 μL min−1 at 83.33 rpm were achieved. The volumetric [16] Choi Y, Powers R, Vernekar V, Frazier A B, LaPlaca M C
and Allen M G 2003 High aspect ratio SU-8 structures for
efficiency was found to increase with rotational speed due to
3-D culturing of neurons ASME Micro-Electromechanical
the diminishing relative effect of internal pump leakage. Systems Division Publication (MEMS) pp 651–4
[17] Al-Halhouli A T 2009 Electromagnetic field analysis on a
Acknowledgments novel electromagnetic actuator for fluid handling
applications PowerMEMS 2009 (Washington, DC, USA)
pp 308–11
This work has been funded by the German Research [18] Tibrewala A, Phataralaoha A and Büttgenbach S 2009
Foundation (DFG) within the framework of the Research Grant Development, fabrication and characterization of a 3D
BU 340/28-1 ‘Development of an Integrated Electromagnetic tactile sensor J. Micromech. Microeng. 19 125005
Micropump for Biomedical Applications’. One of the authors [19] Waldschik A, Feldmann M and Büttgenbach S 2008 Novel
synchronous linear and rotatory micro motors based on
(SB) gratefully acknowledges the financial support of the
polymer magnets with organic and inorganic insulation
Volkswagen Foundation. layers Sensors Transducers J. 3 3–13
[20] Ashraf M, Tayyaba S and Afzulpurkar N 2011 Micro
electromechanical systems (MEMS) based microfluidic
References devices for biomedical applications Int. J. Mol. Sci.
12 3648–704
[1] Zhang C, Xing D and Li Y 2007 Micropumps, microvalves, [21] Ahn S and Kim Y 1998 Fabrication and experiment of a planar
and micromixers within PCR microfluidic chips: advances micro ion drag pump Sensors Actuators A 70 1–5
and trends Biotechnol. Adv. 25 483–514 [22] Yamahata C, Lotto C, Al-Assaf E and Gijs M 2005 A PMMA
[2] Andersson H, van der Wijngaart W, Nilsson P, Enoksson P valveless micropump using electromagnetic actuation
and Stemme G 2001 A valve-less diffuser micropump for Microfluid Nanofluid 1 197–207
microfluidic analytical systems Sensors Actuators B [23] Lemoff A and Lee A 2000 An ac magnetohydrodynamic
72 259–65 micropump Sensors Actuators B 63 179–85
[3] Al-Halhouli A T, Demming S, Feldmann M, Büttgenbach S, [24] Zhou Y and Amirouche F 2011 An
Kilani M I and Al-Salaymeh A 2008 Performance electromagnetically-actuated all-PDMS valveless
characterization of a miniature spiral-channel viscous pump micropump for drug delivery Micromachines
Sensors Actuators A 142 256–62 2 345–55