CORD-CHD
COLLABORATION
Many hospitals throughout the
US and Canada are working
with us to do this study!
WHY PARTICIPATE IN
RESEARCH?
Research allows us to learn and
to improve.
Traditionally, children have
been excluded from research
and this has prevented us from
delivering the best care
possible. By participating in
this research study, you will
help us to take better care of
children born with congenital
CORD-CHD Parent Brochure v. 1, 10.30.2023
CORD-CHD CORD-CHD
VIEW OUR STUDY WEBSITE AND
VIDEO HERE:
CORD CLAMPING AMONG
NEONATES WITH
CONGENITAL HEART
HOW DO I JOIN DISEASE
THE STUDY? A multi-site study sponsored by
the National, Heart, Lung, and
Blood Institute
If you want to be in the CORD-
CHD study, we ask that you
contact your local study
coordinator or doctor.
The study team will need to
talk with you further and
document your consent for you
and your baby to be in this
study. Thank you for taking the
time to review this information!
Scan this QR Code
to View our Study
Website and
This study is listed on the
Video!
heart disease. National Institutes of Health
ClinicalTrials.gov website.

CORD-CHD Parent Brochure v. 1, 10.30.2023

 CORD-CHD
ABOUT THE STUDY
WHAT ARE WE TRYING TO
LEARN?
The CORD-CHD study will see if
a 120 second delay in clamping
the umbilical cord at birth
results in better outcomes
among babies born with
congenital heart disease, as
opposed to a 30-second delay in
clamping.
When it comes to babies born
with congenital heart disease,
they are frequently excluded
from large studies involving
delayed cord clamping.
CORD-CHD will be the 1st large
multi-center study that focuses
on finding out if delayed cord
clamping would be beneficial
among babies diagnosed with
congenital heart disease.
WHO CAN PARTICIPATE?
Both mom and baby will be in
the study. We are mainly looking
to see how delayed umbilical
cord clamping at two different
time points impacts your baby.
However, we also want to see if
this has any impact on you.
CORD-CHD Parent Brochure v. 1, 10.30.2023
CORD-CHD
WHAT WILL
HAPPEN?
BEFORE YOU DELIVER
The study team will review the
ultrasounds of your baby and
wait to see if you give birth
between 37 and 42 weeks. Only
mothers who deliver in the above
window, will be in the study.
DURING DELIVERY
When you are ready to deliver
and if it is between 37-42 weeks
gestation, you will be randomly
assigned to either the 120
seconds or 30 seconds cord
clamping group. Your care team
will still provide all necessary
care to you and your baby in
either group.
AFTER DELIVERY
The study team will continue to
collect information from your
and your baby’s medical record
until you both go home. We will
also watch your baby’s progress
through 26 months of age.
There will be three follow up
CORD-CHD
RISKS & BENEFITS
POTENTIAL BENEFITS
Your doctor will always do what
is best for you and your baby.
Your child may get additional
developmental tests as part of
this study.
You will also have the chance to
give your opinion on what
matters most to families and
caregivers who have a baby with
heart disease.
POTENTIAL RISKS
Both times for clamping the
umbilical cord will not make your
baby’s heart disease worse.
Clamping at 30 or 120 seconds
are considered “usual care” and
could be offered to you without
being in this study.
Sometimes waiting to cut the
cord is not best for you or your
baby, which may mean cutting
the umbilical cord early.
There are no known risks for
either group aside from jaundice.
In the 120 second delay group,
babies may have a greater risk of
having jaundice (yellowing of the
 time points when your baby
reaches the ages of: 3-4
months, 9-12 months, 22-26
months. These follow-up
appointments will take place
over telehealth and the study
team will help you schedule
these.
CORD-CHD Parent Brochure v. 1, 10.30.2023
skin and eyes) due to getting
more blood. This may require
treatment by placing your baby
under special lights. This is a
common treatment for jaundice
and widely available.