PARUL UNIVERSITY

FACULTY OF PHARMACY
QUESTION BANK
B. Pharm. Semester: 3
Subject Code: BP304T
Subject Name: Pharmaceutical Engineering

Long Answers (10 Mark Each)

UNIT I
Sr. Question
No.
1. Explain Bernoulli’s theorem in detail.

2. Show neat and clean diagram of Venturi meter and discuss its principle, construction,
working, advantage, and disadvantages in detail.
3. What do you mean by Energy balance? Discuss Bernoulli’s theorem for total energy
balance with labelled diagram.
4. Describe Bernoulli’s Theorem and discuss its application in detail.
5. Outline a neat sketch of two fluid manometers and explain its working principle.
6. Explain relevant equations for calculation of flow rates using orifice meter.
7. Explain the energy losses that occur when a fluid flows through a pipe with relevant
equations.
8. Define Size reduction. Explain the mechanisms of size reduction with its application
in pharmaceutical industry.
9. Explain Objective, Mechanism & Factor affecting of Size Reduction.
10. Summarize the Principle, Construction, Working, uses, merits & demerits of Ball
mill. With neat and clean Label Diagram.
Or
Identify the mill which is working on the principle of impact & attrition. Explain the
Construction & working of that mill with label diagram.
11. Illustrate the Principle, Construction, Working, uses, merits & demerits of Fluid
Energy mill. With neat and clean Label Diagram.
12. Explain the concept of settling behaviour using water with a suitable Diagram.
13. Explain the behaviour of slurry setting of thickeners with a suitable Diagram.
14. Explain the methods Of size separation of particles in a powder using air as a
medium.
15. Explain the principles of sedimentation of particles using liquid as a Medium.
16. Explain the specific uses and applications of a scrubber. Draw the Sketch of the
equipment.
17. Demonstrate one industrial method for size separation of a powder and its
applications.
UNIT II
18. Draw a neat and clean labeled diagram of single pass or tubular heater and explain in
detail it’s principle, working, construction, advantages, disadvantages and uses.
19. Draw a neat and clean labeled diagram of multipass heater and explain in detail it’s
principle, working, construction, advantages, disadvantages and uses.
20. Draw a neat and clean labeled diagram of floating head heater and explain in detail
its principle, working, construction, advantages, disadvantages and uses.
21. Define Evaporation and explain Application of evaporation in pharmaceutical
industry.
22. Explain the principle, construction, working, uses, advantages and disadvantages of
forced circulation evaporator.

QUESTION BANK Page 1 of 6

PARUL UNIVERSITY
FACULTY OF PHARMACY
QUESTION BANK
B. Pharm. Semester: 3
Subject Code: BP304T
Subject Name: Pharmaceutical Engineering
23. Enlist the film evaporators and explain principle, construction, working, advantage
and disadvantages of climbing film evaporator.
24. Classify evaporators. Describe construction and working of a film evaporator.
25. Describe the construction and working of a distillation apparatus for the preparation
of water for injection.

26. Distinguish between plate column and packed towers. Describe the types of packing
for rectifying columns. How is absolute alcohol made?

27. Explain the principle of fractional distillation and working of fractional distillation
unit.

28. Describe the principle, working and applications of steam distillation.

UNIT II
29. Explain principle, construction, working, uses, advantages and disadvantages of
drum dryer and its uses.
30. Explain the principle, construction, working, advantage and disadvantages of freeze
dryer.
31. Discuss construction,working,advantages, disadvantages and uses of spray dryer.
32. Describe in detail fluidized bed dryer.
33. Define Mixing. Explain the factor affecting of mixing. Illustrate the application of
Mixing in pharmaceutical industry.
34. Explain the principle, construction, working, advantages and Disadvantages of a
Double cone blender with the help of a neat diagram.
35. Summarize the Principle, Construction, Working, uses, merits & Demerits of
planetary mixer with neat and clean Label Diagram.
UNIT IV
36. Explain the construction, working, advantages and disadvantages of filter press.
37. Explain the theories of filtration giving the principle, mechanism and factor affecting
the process.
38. With a neat labelled diagram describe the construction and working of a suitable
industrial filter for handling of high solid containing slurries.
39. With a neat labelled diagram, describe the construction and working of an industrial
filter suitable for clarification of syrups.
40. With neat labelled diagram, describe the construction and working of a chamber
press.
41. Demonstrate the construction and working of a preferred filter suitable for filtration
of high viscous liquids.
42. What is the mechanism of filtration in membrane filter? What are its Advantages and
disadvantages of membrane filters?
43. Draw a neat and clean labeled diagram of ultra centrifuge and write in detail about its
principle, working, construction, advantages, disadvantages and uses.
44. Draw a neat and clean labeled diagram of perforated basket centrifuge and write in
detail about its principle, working, construction, advantages, disadvantages and uses.
45. Draw a neat and clean labeled diagram of Non-perforated basket centrifuge and write

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PARUL UNIVERSITY
FACULTY OF PHARMACY
QUESTION BANK
B. Pharm. Semester: 3
Subject Code: BP304T
Subject Name: Pharmaceutical Engineering
in detail about its principle, working, construction, advantages, disadvantages and
uses.
46. Draw a neat and clean labeled diagram of super centrifuge and write in detail about
its principle, working, construction, advantages, disadvantages and uses.
47. Draw a neat and clean labeled diagram of Semi-centrifuge and write in detail about
its principle, working, construction, advantages, disadvantages and uses.
48. Draw a neat and clean labeled diagram of Filtration and write in detail about its
principle, working, construction, advantages, disadvantages and uses.
UNIT V
49. Describe various types of corrosion and suggest the methods to tackle the same in
pharmaceutical industries.
50. Explain ‘galvanic corrosion and pitting’.

51. Explain the electrochemical theory of corrosion.

52. Discuss factors affecting during materials selected for Pharmaceutical plant
construction

Short Answers (5 Mark Each)

UNIT I
Sr. Question
No.
1. Show neat and clean diagram of orifice meter and discuss its principle and
construction.
2. What is Reynold’s number. Explain its importance with applications.

3. How the Reynold’s number is significant to find a type of flow? Explain the
experiment.
4. Discuss the method to determine Reynolds’s number. Explain application of

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PARUL UNIVERSITY
FACULTY OF PHARMACY
QUESTION BANK
B. Pharm. Semester: 3
Subject Code: BP304T
Subject Name: Pharmaceutical Engineering
Reynolds’s number in pharmacy.
5. Explain energy losses by Friction and loss due to fittings in fluid flow.
6. Write short note on Venturimeter.
7. Compare and contrast the advantages and disadvantages of pitot tube and rotameter
8. Illustrate the difference between orifice meter and venture meter.
9. Explain simple manometer.
10. Explain inclined manometer.
11. Summarize a note on rotameter.
12. Summarize a note on pitot tube.
13. Outline the various laws governing Size Reduction.
14. Summarize in detail about Hammer mill.
15. Justify the sentence. Fluid energy mill is better equipment for size reduction of
thermolabile Substances compared to hammer mill.
16. Why Ball mill is not useful for size reduction of fibrous material.
17. Outline the advantages and disadvantages of size reduction process.
18. Compare ideal and actual screens.What are advantages of expressing sieves by a
sieve number over Nominal size of
aperture?
19. Discuss different modes of size separation
20. List the specifications and standards for sieves
21. Explain the term blinding of screen. How is it prevented?
22. Give the classification of fine powders with definitions.
23. Explain the terminology, normal size of aperture and nominal Diameter of the wire.
24. List the methods of sieve analysis used for testing the powders. Give their relative
advantages.
25. Explain the details about the various standards fixed by the pharmacopoeia For
sieves.
26. Explain the mechanism and applications of Elutriation tank.
27. Explain construction and working of bag filter.
28. Explain principle and working of cyclone separator.
UNIT II
29. Give a short note on Fourier’s law.
30. Give a short note on LMTD theory.
31. Write a note on radiation.
32. Write a note on conduction.
33. Write a note on convection.
34. Describe in detail factors influencing evaporation.
35. Write a note on short tube evaporator.
36. Elaborate the concept of multiple effect evaporation. What specific advantages does
it offers?
37. Explain construction and working of film evaporator of any one type.
38. Explain the construction and working of a forced circulation evaporator.
39. Describe one fractionating column of your choice. List its advantages and
disadvantages.
40. Explain the principle and procedure of molecular distillation what are its

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PARUL UNIVERSITY
FACULTY OF PHARMACY
QUESTION BANK
B. Pharm. Semester: 3
Subject Code: BP304T
Subject Name: Pharmaceutical Engineering
applications?

41. Distinguish evaporation and distillation

42. Differentiate between plate towers and packed towers
43. State Raoult’s law.
44. Define relative volatility and write its significance.

45. Define-flash distillation’. List applications

UNIT III
46. Explain theory behind drying and rate of drying with suitable graph.
47. Compare the operations of spray dryer and tray dryer.
48. Write a detail note on vacuum dryer.
49. List the pharmaceutical applications of freeze-drying process. Give salience features
of the process.
50. Describe the rate of drying curde fibrous drugs.
51. Define drying. Write down the application of drying.
52. Write a note on mechanisms of drying process.
53. How do you classify dryers? Describe in detail the constant rate and falling rate
periods. Add a note on critical moisture content.
54. Discuss the mechanisms of Liquid & Semisolid Mixing.
55. Elaborate the mechanisms of solids mixing
56. Outline the merits and demerits of Double Cone Blender.
57. Explain the construction and working of a ribbon blender for mixing of Solids.
58. Illustrate construction & working of Sigma blade mixer with the help of neat & clean
label diagram.
59. Discuss in detail about Silverson Emulsifier.
60. Explain the turbine mixer with flow pattern.
61. Elaborate merits, demerits & applications of Planetary Mixers.
62. Compare the solid & liquid mixing.
63. Explain the principle, construction, working, advantages and Disadvantages of a
Silverson emulsifier with the help of a neat diagram.
UNIT IV
64. Distinguish surface filtration and depth Filtration.
65. What is meant by the wood sinter? List the uses and advantages of sintered glass
filter.
66. Give the neat labelled diagram of pressure sand filter. What are its Uses?
67. Explain the mechanism by which filter aids improve the rate of filtration.
68. Suggest a method of filtration using vacuum. Explain its role in the Filtration.
69. Explain the theories of filtration.
70. What are filter aids? Name the filter aids commonly used in pharmacy Practice.
71. Discuss the construction and working of a cartridge filter.
72. Explain the construction and working of filter press.
73. Explain the method of washing the residue with a suitable example of Filtration
equipment.
74. Explain the ideal properties of filter media.
75. Compare the features of filter press and filter leaf.

QUESTION BANK Page 5 of 6

PARUL UNIVERSITY
FACULTY OF PHARMACY
QUESTION BANK
B. Pharm. Semester: 3
Subject Code: BP304T
Subject Name: Pharmaceutical Engineering
76. Write the applications of perforated basket centrifuges.
77. Explain the construction and working of semicontinuous centrifuge.
78. Describe the construction and working of supercentrifuge.
79. Give pharmaceutical applications of centrifugation.
80. Explain the principle behind centrifugation.
81. What are the factors influencing centrifugal effect?
82. Define centrifugation and elaborate the objectives behind it.
UNIT V
83. Define corrosion. Give its causes. Classify corrosion.

84. Describe the mechanism of corrosion of iron

85. Explain Ferrous and nonferrous metals.
86. Explain inorganic and organic non metals.
87. Describe basics of material handling system.

MCQ from -Unit 3 and Unit 4

10 marks from Drying and Mixing
5 Marks from Filteration , Centrifugation and Plant Construction

QUESTION BANK Page 6 of 6