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RESEARCH AND EDUCATION

Influence of the postpolymerization type and time on the flexural


strength and dimensional stability of 3D-printed interim resins
Nathalia R. Silva, DDS, MSc, PhD,a Fernanda G. de G. Moreira, DDS, MSc,b Ana B. de C. Cabral, DDS,a
Marco A. Bottino, DDS, MSc, PhD,c Renata M. de M. Marinho, DDS, MSc, PhD,d and
Rodrigo O.A. Souza, DDS, MSc, PhDe

ABSTRACT
Statement of problem. The mechanical strength of 3-dimensionally (3D) printed interim resins is unclear but influenced by printing
parameters. Evidence regarding standardization of the postpolymerization type and time for 3D-printed interim resins is sparse.
Purpose. The purpose of this in vitro study was to evaluate the influence of postpolymerization type and time on flexural strength and
dimensional stability of 3D-printed resins for interim restorations.
Material and methods. A total of 288 bars were 3D printed (Form 2; Formlabs, stereolithography—SLA, 50 µm, 30 degrees), (25×2×2 mm;
International Organization for Standardization—ISO 4049:2019) abraded and randomly divided into 9 groups (n=30) according to
postpolymerization (Ultraviolet device—UV; Microwave with water—MWA; Microwave without water—MW) and time (15, 20, and
30 minutes for UV; and 5, 8, and 10 minutes for MW and MWA). Each bar was then measured with digital calipers at 11 points for length,
thickness, and width before and after postpolymerization to analyze dimensional stability. The flexural strength was then measured
(σ; 980.6 N, 1 mm/minute) and the fractured surfaces were analyzed with scanning electron microscopy. The σ (MPa) data were evaluated
by using a 2-way analysis of variance (ANOVA) and the Tukey honestly significant difference (HSD) pairwise comparisons test (α=.05).
Dimensional stability data (mm) were analyzed by using the Kruskal-Wallis test and Dwass-Steel-Critchlow-Fligner multiple comparisons.
The Weibull analysis was performed with σ data.
Results. The 2-way ANOVA revealed that all factors and their interaction were significant for σ (P<.001). The UV groups presented the
highest σ values, being statistically higher than all MW and MWA groups. The Weibull analysis revealed that postpolymerization UV groups
found the highest values regarding the characteristic strength, although the MW 8-minute group (13.71) found the highest value for the
Weibull modulus. Furthermore, the Kruskal-Wallis test revealed that only the postpolymerization factor was significant for dimensional
stability (P<.001). The postpolymerization microwave groups found greater expansion variations at all times, with the MW 8-minute group
(0.78 ±0.54) presenting the greatest variation in dimensional stability.
Conclusions. UV was determined to be the most suitable type of postpolymerization for interim printed resin among the
postpolymerization methods, regardless of the application time. The postpolymerization MW groups found greater variations in
dimensional stability. (J Prosthet Dent xxxx;xxx:xxx-xxx)

Presented at the Brazilian Society for Research in Dentistry (SBPQO), Annual Meeting, Campinas, São Paulo, Brazil, September 2022.
Funding: Supported in part by the Coordination for the Development of Higher Education Personnel (CAPES) (finance code 001), Brazil. Materials used in study were
provided by Oral Way Laboratory (Natal/RN, Brazil) and Yller (Pelotas/RS, Brazil).
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this article.
a
Researcher, Department of Dentistry, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
b
PhD student, Department of Dentistry, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
c
Professor, São Paulo State University (UNESP), Institute of Science and Technology, São Paulo, Brazil.
d
Researcher, São Paulo State University (UNESP), Institute of Science and Technology, São Paulo, Brazil.
e
Professor, Department of Dentistry, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.

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MW postpolymerization has been reported to improve


Clinical Implications the degree of conversion of composite resin and denture
Resins for manufacturing 3D-printed interim base acrylic resins.30–33 However, evidence for its use for
restorations should preferably be postpolymerized postpolymerization of printed resins is lacking.
The present study aimed to evaluate the influence of
with ultraviolet light because it promotes better
mechanical characteristics and less dimensional postpolymerization type and time on the flexural
change in relation to alternative strength and dimensional stability of 3D-printed interim
postpolymerization protocols in a microwave oven. resins. The research hypotheses were that the post­
polymerization type would influence the flexural
strength of the 3D-printed interim resin specimens, that
Computer-aided design and computer-aided manu­ a longer postpolymerization time would increase the
facturing (CAD-CAM) technology enabled producing flexural strength of the 3D-printed resin, and that di­
interim and definitive restorations with satisfactory mensional stability would be influenced by the post­
precision and adaptation through a digital workflow.1 polymerization type and times.
The use of 3-dimensional (3D) printing has become
popular for making interim restorations2 and has the
MATERIAL AND METHODS
advantage of reducing working time, with greater pre­
dictability and comfort for the patient compared with The specimens were designed in a software program
conventional fabrication techniques.3–5 (Meshmixer; Autodesk Inc) and a standard tessellation
Interim restorations must be able to resist mastica­ language file was obtained, which was then exported to
tory loads and have adequate dimensional stability so the printer software program (PreForm; Formlabs Inc),
that the restoration adapts to the tooth preparation. and the specimens printed by the stereolithography
Printed interim restorations have been reported to have technique in a 3D printer (Form 2; Formlabs Inc). Before
greater hardness6 and better flexural strength when than printing, the angle of the bars was configured in a
autopolymerized acrylic resins.7 However, the low me­ software program (PreForm; Formlabs Inc) with a
chanical strength of printed resins has also been re­ 30-degree angle and with a 50-μm print layer thickness.
ported.8 Then, 288 bars (26×2.2×2.2 mm) were printed with the
Dimensional stability9 is also important and is di­ interim resin (Cosmos Temp; Yller).
rectly related to the adaptation of interim crowns.10 After printing, the specimens were cleaned with iso­
Printed interim resins have been reported to have better propyl alcohol and had their fixation supports removed with
marginal and internal adaptation11 and better occlusal a double-sided diamond disk (22 mm×0.15 mm; Dhpro) in
accuracy12 than milled crowns or those fabricated with a straight handpiece and a manual benchtop micromotor
the lost wax technique. However, when comparing (500; Kavo). All bars were abraded with 600-, 800-, and
printed resin, milled polymethylmethacrylate (PMMA), 1200-grit abrasive article to the definitive dimensions
and acrylic resin, Mohajeri et al13 reported marginal (25×2×2 mm) specified by the International Organization
misfit values of 91.40, 75.28, and 51.23 µm, respectively, for Standardization (ISO) 4049:2019 standard.34 The bars
with these values being considered clinically acceptable were numbered, and simple randomization was performed
(below 150 µm).14,15 to subdivide the specimens into 9 groups (n=30) according
The mechanical strength11 and dimensional stabi­ to the “postpolymerization” (3 levels) and “time” (3 levels)
16
lity of 3D-printed interim restorations depend on factors (Fig. 1). The information regarding the post­
factors that include resin type,17 printer type,18 post­ polymerization devices and times are specified in Table 1.
polymerization technique,19 and printing parameters, The postpolymerization times for the UV and MW groups
including the angle,20,21 speed,22 orientation,23 and print were based on a pilot study (n=5) and the recommenda­
layer thickness.24 Among these factors, post­ tions of the manufacturer for the UV device.
polymerization is a postprinting step to increase the The specimens were measured with high-precision di­
degree of conversion of the resin through polymerizing gital calipers (Digital Absolute AOS; Mitutoyo) at 11 points:
unreacted monomers.25,26 Postpolymerization of 3D- 5 thickness, 5 height, and 1 length, before and after post­
printed restorations is currently done with devices that polymerization. The mean surface area of each specimen
combine ultraviolet (UV) light and heat. The duration of was calculated, and the dimensional change analyzed by
this exposure to UV light can influence aspects such as calculating the subtracted area of the printed bar in relation
polymerization degree, surface roughness, mechanical to the processed postpolymerized bar.
properties, and the accuracy of printed objects.24–29 All specimens were 3-point flexural strength tested in
Most previous studies24–29 investigated UV light as a universal testing machine (Microtensile OM150;
the postpolymerization method. However, some den­ Odeme Biotechnology) adjusted according to the di­
tists may postpolymerize in a microwave (MW) oven. mensions of the bar in accordance with ISO 4049:201934

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Does postpolymerization type and time influence flexural strength, dimensional


Research question
stability, and microscopic characteristics of 3D-printed interim resin?

I) Postpolymerization type influences flexural strength of 3D-printed resin;


Hypotheses II) Longer postpolymerization time increses flexural strength of 3D-printed resin:
III) Dimensional stability is influenced by postpolymerization type and times.

Specimen 288 3D-printed bars (26 × 2 × 2 mm) using stereolithography (SLA) technique -
preparation Angulation: 30 degrees / Thickness 50 µm.

•Ultraviolet Light (UV): Ultraviolet device (Anycubic Wash & Cure Plus; Anycubic,
450 nm, 40 W) for 15, 20, and 30 minutes;
Postpolymerization •Microwave (MN): Microwave (MRAS21: Midea; 700 W) for 5, 8 and 10 minutes;
protocols
•Microwave + water (MWA): Microwave (MRAS21; Midea; 700 W) for 5, 8, and 10
minutes, immersed in water

Flexural strength Weilbull Dimensional stability Scanning Electron


(n=30) analysis (n=30) Microscopy (n=2)

Figure 1. Flowchart of study design.

The test power was evaluated by using the OpenEpi


Table 1. Postpolymerization groups, model, manufacture, power of website. Data normality and homoscedasticity were
devices, and time of application evaluated by using the Kolmogorov-Smirnov and
Postpolymerization Postpolymerization Times Levene tests, respectively. A comparison among groups
Groups Device
Ultraviolet light (UV) Anycubic Wash & Cure 15 min
was performed by 2-way analysis of variance (ANOVA)
Plus; Anycubic, 40 W 20 min (postpolymerization type, postpolymerization time) and
30 min the Tukey honestly significant difference (HSD) pairwise
Microwave (MW) MRAS21; Midea; 70 W 05 min
08 min comparisons test (α=.05) for the flexural strength data
10 min with a computer program (Statistix v.8.0; Analytical
Microwave with MRAS21; Midea; 70 W 05 min
specimens immersed in 08 min Software). Descriptive analysis was performed for the
water (MWA) 10 min SEM analysis.
The dimensional stability data were analyzed by
using the Kruskal-Wallis test and Dwass-Steel-
with a crosshead speed of 1 mm/min and a 980.6-N load Critchlow-Fligner multiple comparisons in a computer
cell. The flexural strength in MPa was calculated based program (Jamovi v.2.3; The Jamovi project).
on the load at rupture according to the equation: A Weibull analysis was performed to evaluate the
3lF
FS = 2wh2 , where FS is the flexural strength (MPa), l is flexural strength reliability by the Weibull parameter (m)
the distance (mm) between the centers of the lower and the characteristic strength (σo) with a 95% con­
rollers, F the load (N) applied at the rupture moment, h fidence interval, which were calculated by the ln{ln
the thickness (mm), and w the width. Two additional [1/(1 – F(σc)]} versus lnσc being diagram (according to
specimens from each experimental group were made for ENV 843-5): lnln(1/(1 F( c))) = mln c mln o.
analysis with a scanning electron microscope (TM 3000; The characteristic strength is the resistance to a failure
HITACHI) at ×3000 to observe changes in the surface probability of approximately 63.3%, and the Weibull mod­
topography resulting from postpolymerization. ulus (m) was used as a measure of the strength distribution,

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1.e4 Volume xxx Issue xx

which expressed the structural homogeneity of the material. and UV 30-minute (11.47) groups presented the highest
The statistical analysis was performed with a software values for the Weibull modulus.
program (Minitab v.17; Minitab Inc) (α=.05). The dimensional stability data did not present
normal distribution (P<.001). The comparison between
the area variation values was significant for the “post­
polymerization” factor (P<.001). The multiple Dwass-
RESULTS
Steel-Critchlow-Fligner comparisons for the post­
The test power calculated by comparing means was polymerization type revealed that the interaction among
100%. The flexural strength data had a normal and the “MW and MWA” and “MW and UV” groups was
homogeneous distribution (P<.05). Two-way ANOVA significant (P<.001); however, the interaction between
revealed that the “postpolymerization” (P<.001) and the groups “MWA and UV” were not significant
“time” (P<.0001) factors, and the interaction (P<.001) (P=.423). The groups postpolymerized in MW presented
were significant (Table 2). The Tukey test (5%) found the biggest expansions (Fig. 3). Among the groups
that there was no significant difference among all groups submitted to postpolymerization in a microwave oven,
submitted UV for 30 minutes (77.90 ±8.23)A, 15 minutes the MW 8-minute group (0.78 ±0.54) found the greatest
(73.99 ±8.15)A, and 20 minutes (73.80 ±10.18)A, which variation in dimensional stability. Moreover, the MWA
were statistically higher than the other experimental groups presented the lowest expansion values at times
groups (Fig. 2). Among the results of the groups sub­ of 5 minutes (0.14 ±0.18) and 8 minutes (0.14 ±0.18),
mitted to postpolymerization in a microwave oven, the and there was no significant difference between them.
MW 8-min group (45.58 ±3.84)B obtained higher flex­ Regarding the ultraviolet postpolymerized groups, the
ural strength when compared with the other times (with UV 15-minute group found greater variation in its di­
or without water), with no significant difference among mensions (0.37 ±0.37) when compared with the other
them (Table 3). The Weibull analysis data are shown in UV 20-minute (0.19 ±0.21), and UV 30-minute
Table 2. Characteristic strength (P<.001) and Weibull (0.22 ±0.28) groups, and there was no significant dif­
modulus (P<.001) were significantly different. Regarding ference between them (Table 3).
the characteristic strength, the UV 15-minute group The SEM for the fractured surface of 3D-printed resin
presented the highest values. The MW 8-minute (13.71) specimens found that the UV groups (Fig. 4A-C) formed

Table 2. Two-way ANOVA results for flexural strength data


Source GL SQ QM F P
Postpolymerization 2 121 237 60618.5 1373.77 <.001a
Time 2 1367 683.7 15.50 <.001a
Postpolymerizationa Time 4 5291 1322.7 29.98 <.001a
Erro 261 11 517 44.1
Total 269 139 412
DF, degree of freedom; f, F-statistic; QM, mean square; SS, sum of square.
a
Statistically significant (P<.05).

100
90 A A A
Flexural Strength (MPa)

80
70
60
B
50
40 C C C C
C
30
20
10
0
15 min 20 min 30 min 5 min 8 min 10 min 5 min 8 min 10 min
UV MW MWA

Figure 2. Mean 3-point flexural strength (MPa) and standard deviation of groups according to postpolymerization type and time. Different
uppercase letters indicate statistical difference for flexural strength. MW, microwave; MWA, microwave + water; UV, ultraviolet.

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Table 3. Flexural strength (MPa), characteristic strength (σo), Weibull modulus (m), and respective CI for each group
Postpolymerization Time Flexural Characteristic 95% CI for Weibull 95% CI Variation
Strength Strength σo (MPa) Modulus (m) for m (mm)
(MPa) (σo) (MPa)
UV 15 min 73.99 ±8.15A 77.56a 74.79-80.44 10.34ɑ� 7.40-14.44 0.37 ±0.37‡
20 min 73.80 ±10.18A 77.99a 74.59-81.56 8.50ɑ�ɣ 6.70-10.78 0.19 ±0.21╬
30 min 77.90 ±8.23A 81.30a 78.64-84.05 11.47ɑ 9.17-14.36 0.22 ±0.28╬
MW 05 min 26.44 ±6.13C 28.90cd 26.66-31.34 4.66ɣ 3.41-6.35 0.44 ±0.46‡
08 min 45.58 ±3.84B 47.28b 46.00-48.60 13.71ɑ 9.80-19.18 0.78 ±0.54┼
10 min 29.94 ±3.79C 31.43c 30.22-32.68 9.82ɑ� 7.89-12.23 0.59 ±0.37╪
MWA 05 min 28.75 ±6.36C 31.24cd 29.01-33.64 5.09�ɣ 3.78-6.84 0.14 ±0.18╫
08 min 26.11 ±4.43C 27.89d 26.40-29.46 6.88ɑ�ɣ 5.17-9.16 0.14 ±0.18╫
10 min 27.08 ±5.71C 29.46cd 27.32-31.76 5.02�ɣ 3.40-7.41 0.17 ±0.23║
MW, microwave; MWA, microwave + water; UV, ultraviolet.
*Different uppercase letters indicate statistical difference for flexural strength. Different lowercase letters indicate statistical difference for char­
acteristic resistance. Different Greek letters indicate statistical difference for Weibull module. Different symbols indicate statistical difference for
dimensional stability.

The importance of postpolymerization has been well


Variation of Dimensional

2.0 discussed previously, showing evidence that its ability to


promote improvements in the properties of 3D printed
Stability (mm)

1.5 parts is essential for mechanical strength, in addition to


also influencing the degree of conversion and surface
1.0 roughness.26 However, studies which have compared
alternative methods to the UV device are lacking. Thus,
0.5 it becomes necessary to standardize a correct protocol
for postpolymerization to achieve the best results for
0.0 3D-printed resin interim restorations.
MW MWA UV The hypothesis that the postpolymerization type
Post-polymerization would influence the flexural strength of the 3D-printed
Figure 3. Variation of the dimensional stability (mm) of groups interim resin specimens was accepted. Postpolymerization
according to postpolymerization factor. MW, microwave; MWA, with an ultraviolet device, regardless of the time variation,
microwave + water; UV, ultraviolet. promoted significantly greater mechanical strength.
However, the mechanical strength of the microwave post­
polymerized printed resin, with and without water, was
a complex pattern that has multiple structures with ir­ lower compared with the UV device, which presented
regular exfoliated layers. It was also possible to observe a higher flexural strength to the other microwave groups. In
flatter surface, with some grooves for the MW 05-minute addition, the characteristic strength results found a similar
group (Fig. 4D), and also with exfoliated layers for the tendency to the flexural strength, so the UV groups found
MW 10-minute group (Fig. 4F). The predominance of a the highest values. The Weibull modulus indicated that the
flatter surface for the material polymerized by MW 08- specimens submitted to UV at all times, MW 8-minute and
minute group (Fig. 4E) and MWA groups (Fig. 4G-I), MW 10-minute groups, and MWA 8-minute group pre­
indicating that the material did not present high sented similar values, indicating that these groups present
strength against the applied load. more reliable behavior of the material.
Factors such as the postpolymerization type as well
as the exposure time have been reported to influence the
DISCUSSION
mechanical properties of 3D-printed resins.24–29 How­
The present study evaluated the influence of different ever, comparisons of different postpolymerization
postpolymerization forms, as well as the time variation of methods with better cost-effectiveness in relation to UV,
each of these methods, on the flexural strength and di­ the method recommended by the manufacturers, are
mensional stability of 3D-printed interim resin specimens. lacking. Previous studies have indicated that the use of
The times presented in this study were based on a previous microwaves can accelerate the polymerization rate and
pilot study and also on the recommendations of the man­ increase the extent of polymerization of the composite
ufacturer of the UV device. It was observed during the resin30 through greater conversion of monomers into
pilot study that increased microwave exposure produced polymeric chains32 thereby, promoting improvements in
considerable damage to the resin specimens. Thus, shorter microhardness, strength, fracture toughness, wear re­
times were used for the microwave groups than the UV sistance and color stability of the printed resin.30,32 In
groups selected for this study. addition, Grazioli et al32 reported a 52% increase in the

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1.e6 Volume xxx Issue xx

A B C

D E F

G H I

Figure 4. Scanning electron micrographs (original magnification ×500). A, UV 15 min. B, UV 20 min. C, UV 30 min. D, MW 05 min. E, MW 08 min. F,
MW 10 min. G, MWA 05 min. H, MWA 08 min. I, MWA 10 min. MW, microwave; MWA, microwave + water; UV, ultraviolet. Red asterisks indicate
grooves. Yellow arrows indicate an irregular layer structure with chips.

surface hardness of composite resins postprocessed with the increase from 10 to 20 minutes did not produce sig­
microwaves. However, despite the similarities between nificant differences in flexural strength.28 Nevertheless, in­
the composite resin and the printed resin, the groups creasing the postpolymerization time from 60 to 90 minutes
postpolymerized in a microwave oven in this study was reported to improve mechanical performance and the
found lower flexural strengths. Likewise, a decrease in conversion degree of 3D printed resins.19 Although the time
the flexural strength of this material was observed when factor did not affect flexural strength in this study, our re­
a microwave oven was used for postpolymerizing the sults highlight the importance of the postpolymerization
PMMA.31 with UV, independent of the time of exposure, because
The hypothesis that a longer postpolymerization time comparable results were not achieved when comparing
would increase the flexural strength of the 3D-printed resin with alternative methods such as microwaves in terms of
was rejected because the postpolymerization time did not the mechanical property of the printed resin for interim
significantly affect the mechanical strength of the specimens restorations.
subjected to UV. The manufacturers recommend a post­ SEM analysis in the present study found that the groups
polymerization UV exposure time of 10 minutes for the submitted to postpolymerization in a UV device presented a
resin tested. Increasing the postpolymerization time with fracture surface with characteristics of a more ductile ma­
UV from 5 minutes to 10 or 20 minutes has been reported to terial. According to Aati et al,28 these characteristics provide
increase the flexural strength of printed resins,29 although the surface of a material with fragile mechanical behavior.

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These findings were also consistent with Kim et al,19 who 4. Kessler A, Reinhard H, Reymus M. 3D Printing in dentistry-state of the art.
Oper Dent. 2020;45:30–40.
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and resin postpolymerization time for 3D-printed interim Transferring art from the laboratories to the clinics. Polymers. 2021;13:157.
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restorations. The hypothesis that dimensional stability microhardness of provisional crown and bridge materials fabricated by
would be influenced by the postpolymerization type and different methods. J Indian Prosthodont. 2016;16:328–334.
times was accepted. Daneu et al9 specified that dimensional 7. Pantea M, Ciocoiu RC, Greabu M, et al. Compressive and flexural strength
of 3D-printed and conventional resins designated for interim fixed dental
stability consists of the ability of a polymer to maintain its prostheses: An in vitro comparison. Materials. 2022;15:3075.
8. Simoneti DM, Pereira-Cenci T, Dos Santos MBF. Comparison of material
dimensions even under different conditions. In the present properties and biofilm formation in interim single crowns obtained by 3D
study, the groups postpolymerized in a microwave oven printing and conventional methods. J Prosthet Dent. 2022;127:
168–172.
found greater expansion after postpolymerization. The ac­ 9. Daneu GD, de B Vasconcelos J, Oltramari PV, et al. Dimensional stability of
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25. Bayarsaikhan E, Lim JH, Shin SH, et al. Effects of postcuring temperature on
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28. Aati S, Akram Z, Shrestha B, et al. Effect of post-curing light exposure time Corresponding author:
on the physico-mechanical properties and cytotoxicity of 3D-printed Dr Rodrigo Othávio Assunção Souza
denture base material. Dent Mater. 2022;38:57–67. Department of Dentistry
29. Soto-Montero J, de Castro EF, Romano B, de C, Nima G, Shimokawa CAK, Federal University of Rio Grande do Norte (UFRN)
Giannini M. Color alterations, flexural strength, and microhardness of 3D Avenida Salgado Filho, 1787
printed resins for fixed provisional restoration using different post-curing Lagoa Nova, Natal, Rio Grande do Norte 59056-000
times. Dent Mater. 2022;38:1271–1282. BRAZIL
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2018;115:88–103. The authors thank Oral Way Laboratory (Natal/RN, Brazil) and the company
31. Ozkir SE, Yilmaz B, Unal SM, Culhaoglu A, Kurkcuoglu I. Effect of heat Yller (Pelotas/RS, Brazil) for the provision of materials used in this study.
polymerization conditions and microwave on the flexural strength of CRediT authorship contribution statement
polymethyl methacrylate. Eur J Dent. 2018;12:116–119. Nathalia Ramos da Silva: Conceptualization, Methodology, Formal analysis, and
32. Grazioli G, Francia A, Cuevas-Suárez CE, Zanchi CH, Moraes RR. Simple Writing — original draft, Fernanda Gurgel de Gois Moreira: Methodology, Formal
and low-cost thermal treatments on direct resin composites for indirect use. analysis, and Writing — original draft, Ana Beatriz de Carvalho Cabral:
Braz Dent J. 2019;30:279–284. Methodology, and Writing — original draft, Marco Antonio Bottino:
33. Costa RMB, Venante HS, Pordeus MD, et al. Does microwave disinfection Conceptualization, Writing — review & editing, Renata Marques de Melo
affect the dimensional stability of denture base acrylic resins? A systematic Marinho: Conceptualization, Writing — review & editing, Rodrigo Othávio de
review. Gerodontology. 2022;39:339–347. assunção e Souza: Conceptualization, Writing — review & editing, Supervision.
34. International Organization for Standardization. ISO 4049.
Dentistry—Polymer-based restorative materials. Geneva: International Copyright © 2023 by the Editorial Council of The Journal of Prosthetic Dentistry.
Organization for Standardization; 2019. https://www.iso.org/standard/ All rights reserved.
67596.html [Accessed April 4 2022]. https://doi.org/10.1016/j.prosdent.2023.07.030

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