Essay Perfume

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artistic elements. It's not merely about expressing personal opinions; it necessitates a delicate balance
between descriptive language and analytical insight.

Describing scents is inherently abstract and subjective, making it a formidable task to convey the
olfactory experience through words. A writer must rely on a rich vocabulary and creative expressions
to capture the essence of different fragrances, considering that readers can't physically smell what is
being described.

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perfume – exploring its impact on emotions, memories, and human connections. Understanding the
cultural and historical contexts of specific fragrances adds another layer of complexity to the writing
process.

Research becomes crucial, as delving into the origins of perfumery, the evolution of scent preferences
over time, and the significance of certain fragrances in various societies adds depth to the narrative.
Incorporating relevant data, anecdotes, and expert opinions enhances the essay's credibility and
provides a well-rounded perspective.

Balancing technical information with artistic appreciation is a delicate dance. The writer must avoid
becoming too technical and alienating readers who might not have a deep understanding of
perfumery, while still maintaining a level of sophistication and depth that reflects the complexity of
the subject.

In conclusion, writing an essay on the topic of "Essay Perfume" demands a unique set of skills – a
mastery of descriptive language, an appreciation for the cultural and historical nuances of perfumery,
and the ability to evoke emotions through words. It's a task that requires both creativity and
precision, making it a formidable challenge for any writer.

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Essay Perfume Essay Perfume
 Assignment ( Hatters ) ( Transthyretin )
B30001 Assignment (Hatters) Transthyretin

Benjamin Andrikopoulos759192

Introduction to TTR:

Transthyretin (TTR) is a protein in the blood (serum) and cerebrospinal fluid of

humans that functions in the transport of the thyroid hormone thyroxine (T4) and
retinol (also known as Vitamin A1). [1] It is secreted by the liver into the blood and
by the choroid plexus into the cerebrospinal fluid. [2] Studies have shown that as less
than 1% of TTR s T4 binding sites (T4BS) in the blood are in use and occupied, new
drug designs can be specialised and optimised to bind to these sites, thus preventing TTR
misfolding, dissociation, and aggregation. [4] Amyloid diseases are associated with the
misfolding and dissociation of the TTR tetramer and ... Show more content on
Helpwriting.net ...
Figure 1.Three dimensional cartoon style structure of transthyretin (TTR) showing two
monomers/one dimer of the dimer of dimers quaternary structure (monomers pink and
orange) at the binding interface. Stick style top view of AG10 (blue) highlighting two
binding sites per tetramer and key binding serine and lysine residues S117 and K15 of
TTR (green). All monomers of TTR contain 1 α helix and an 8 stranded β sheet with
Greek key topology.

Interaction differences AG10 vs. tafamidis:

With AG10 binding to TTR, the dimethyl pyrazole like ring of AG10 sits deep within
the T4BS cavity, forming two H bonds to two Ser117 residues of subunits adjacent to
each other. The CH3 pair of the pyrazole ring are positioned into halogen binding
pocket 3 (HBP 3), which is considered a hydrophobic area. [4] The terminal COOH
group on the benzene ring allows for van der Waals interactions with the side chain
amino groups of the two Lys15 residues directly on different monomers at the edge of the
T4BS, with the F moiety in the para position fitting into HBP 1. These interactions close
to the binding environment surrounding AG10 are protected in part from the surrounding
solvent, leading to high affinity binding of AG10 to TTR. [4]

Contrasting with tafamidis hydrogen bonding is absent at the base of the binding pocket
like with AG10, but the Cl substituents are instead located in HBP 3, where
hydrophobically the subunits are bridged. [4] This absence of additional
 Much Madness Is Divinest Sense By Sherman Alexie
The phrase knowledge is power just so happens to be one of the most commonly uttered
didactic quotes used today. When reading these short stories and poems, I was able to
identify quite a number of claims that were being inferred, and correlate to the topic of
knowledge and individual power. In the short story: Superman and Me by Sherman
Alexie, and the two poems Much Madness is Divinest Sense by Emily Dickinson and
Crazy Courage by Alma Villanueva; the three raconteurs are able to describe their own
intuitive concepts and claims of knowledge and individualpower meanderingly through
these poems and stories. After reading the three works, I was able to notice similarities
in how each writer describes knowledge as individual power, also presenting the similar
ethics. A few claims that mainly stood out to me specifically in these three readings
would be: clarity, individualism, nonconformity, strength and courage.
In the first short story I read Superman and Me , the young boy Alexie, had a passion for
reading, consequential from his love and admiration of his father. ... Show more content
on Helpwriting.net ...
Dickinson uses a resilient voice to express to the readers her anger towards humanity,
due to their lack of clarity, individualism and sovereignty. You can sense her
despondency towards the system and how people just accept something illogical,
solely based on the fact that it is accepted by the majority .While reading further into
the poem, Dickinson states people who are crazy are actually sane and those who claim
to be sane are actually crazy. The poem continues in that direction, informing that the
vast majority of people, only see the madness in the world, convicting all those who
disagree against the mainstream. If you have the audacity to be a nonconformist and
sustain your individuality, regardless of how you are viewed or judged. With clarity,
you will see the world for what it really