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Objective: To develop a brief alcohol and other drug ment (T$55). Sensitivity and specificity rates for pre-
(AOD) screening test for adolescents. dicting a PICS T score of 55 or higher were calculated
from 2 3 2 tables.
Methods: A 9-item test was constructed by combining and
modifying items from several AOD assessments, and ad- Results: Ninety-nine adolescents were tested (70.7% fe-
ministered concurrently with the Personal Involvement male, 36.4% black, 32.3% white, 19.2% Hispanic, mean
With Chemicals Scale (PICS), the criterion standard. age, 16.3 years). The 9 items had good internal consis-
tency (Cronbach a = .79). Stepwise linear regression analy-
Setting: A hospital-based adolescent clinic. sis identified 6 items whose total combined score was
highly correlated with PICS (Pearson r = 0.84, P,.01).
Subjects: Fourteen- to 18-year-old patients consecu- This model correctly classified 86% of subjects accord-
tively arriving for routine medical care who were known ing to the PICS criteria. Two or more yes answers had a
to have used AOD. sensitivity of 92.3% and specificity of 82.1% for inten-
sive AOD treatment need. The 6 items were arranged into
Measures: Internal consistency of the 9 items was cal- a mnemonic (CRAFFT).
culated using the Cronbach a. The relationship be-
tween the brief screen and PICS raw score was deter- Conclusions: Further research must confirm the test’s
mined by stepwise linear regression analysis. The PICS psychometric properties in a general clinic population.
T score has been shown to correctly classify substance However, CRAFFT seems promising as a brief AOD
abuse treatment need as no treatment (T,35), brief of- screening test.
fice intervention (T = 35-40), outpatient or short-term
treatment (T = 41-54), and inpatient or long-term treat- Arch Pediatr Adolesc Med. 1999;153:591-596
S
UBSTANCE USE and abuse has nal and Child Health Bureau’s Bright
been considered the num- Futures: Guidelines for Health Supervision
ber 1 health problem in the of Infants, Children, and Adolescents,8 ev-
United States.1 Recent epide- ery adolescent should be screened for use
miological data indicate drug of alcohol or other drugs (AOD) as part
From the Divisions of General use by students in grades 8 through 12 has of routine health care. A policy statement
Pediatrics (Dr Knight) and risen significantly since 1990, and adoles- recently published by the American Acad-
Adolescent and Young Adult cents are beginning to drink at younger emy of Pediatrics Committee on Sub-
Medicine (Drs Shrier and ages.2,3 Thirty-two percent of high school stance Abuse states that pediatricians
Bravender), Children’s students binge drink ($5 drinks in a row) should be “able to evaluate the nature and
Hospital, and Division on
Addictions, Harvard Medical
and 15.4% drive after drinking.4 Even more extent of . . . alcohol and other drug use
School (Drs Knight and Shaffer alarming, 38.8% of surveyed students in among their patients . . . and make an as-
and Ms Vander Bilt), Boston, grades 9 through 12 reported riding in a sessment as to whether additional coun-
Mass; and Colby College and car with a driver who had been drink- seling or referral may be needed.”9 How-
Harvard BASE Project, ing.4 This is particularly concerning as mo- ever, surveys of practicing pediatricians
Waterville, Me (Ms Farrell). tor vehicle crashes are the leading cause indicate that fewer than half actually per-
A 9-item screening test was constructed by taking indi- A research assistant verbally administered the 9-item screen
vidual questions from the RAFFT, DAP, and POSIT and asked each subject to complete the PICS from the Per-
(Table 1). Specific items were chosen because they had sonal Experience Inventory (PEI).23 The PEI has been well
been found to be sensitive and specific in prior validation validated, and the PICS T score has been shown to cor-
studies, and/or because they were deemed to be clinically rectly classify substance abuse treament need as follows:
relevant and important. Questions were modified to in- no treatment (T,35), brief office intervention (T = 35-
clude the word “drugs” as well as the word “alcohol,” and 40), outpatient/short-term treatment (T = 41-54), and in-
most were qualified by “Have you (or do you) ever. . .”. patient/long-term treatment (T$55).24 The PICS scale was
These modifications provided consistency among items and used as the criterion standard in this study. The sample was
enhanced the sensitivity of the screen. randomized for order of test administration (9-item screen
and then PICS vs PICS and then 9-item screen) and strati-
SUBJECTS fied for sex. Subjects were offered a free movie pass or fast-
food voucher for their participation. Based on the Guide-
The test was administered to a sample of patients consecu- lines for Adolescent Health Research, 25 the Children’s
tively arriving for routine medical care at an adolescent clinic. Hospital investigational review board waived parental con-
Patients aged 14 to 18 years who had a history of AOD use sent for this study.
were invited to participate by their primary care provider. Pa-
tients who could not speak English or who were judged to DATA ANALYSIS
be medically unstable or in crisis (eg, in need of a pregnancy
test) were not asked to participate. No data were collected The research assistant entered all data into the Statistical
on subjects who were excluded or refused participation. Cli- Program for the Social Sciences (SPSS Inc, Chicago, Ill) for
nicians, however, made an effort to include adolescents whose Microsoft Windows 7.5. Demographic frequencies, means,
current AOD use was thought to be significant, as the goal and SDs were determined. A t test was performed for or-
of the study was to develop a brief test that could determine der of test administration. The PICS T scores were calcu-
which patients need referral to specialty treatment. lated for purposes of standardization. Correlations were ana-
lyzed with Pearson r statistics and internal consistency
SETTING reliability was assessed using Cronbach a. A stepwise lin-
ear regression analysis was performed using the PICS raw
The study was conducted in the Adolescent and Young Adult score as the independent variable. Sensitivity, specificity,
Medical Practice at Children’s Hospital, Boston, Mass. Chil- and positive and negative predictive values were calcu-
dren’s Hospital is a large tertiary care teaching hospital. The lated from frequency tables.
form such a screening.10 The reasons for this low level of felt bad or guilty about your drinking?” “Have you ever
compliance are unknown. Pediatricians may lack suffi- had a drink first thing in the morning to steady your nerves
cient training or be reluctant to initiate screening for a prob- or get rid of a hangover (eye opener)?” The CAGE ques-
lem that they believe is both difficult to treat and time- tions have several advantages that undoubtedly account
consuming to assess. Development of a brief and effective for its popularity among clinicians. It is brief, verbally
method for AOD screening, assessment, and interven- administered, easy to remember, and easy to score (each
tion may therefore substantially improve practices among yes answer = 1). The CAGE questions have been shown
pediatricians. The first step in formalizing a clinical man- to have high sensitivity and specificity in medical set-
agement strategy must be the development of a practical tings, with a score of 2 or greater indicating a high prob-
screening tool. ability of an alcohol-related diagnosis.16 It has not been
Several brief screening tests have been developed for validated among adolescents, however, and some items
use among adults. In recent years, the Alcohol Use Dis- (eg, the “eye opener” question) are not developmentally
orders Identification Test (AUDIT) has become widely appropriate for teenagers.
known and used.11-13 The AUDIT is a 10-item question- Several screening questionnaires have been de-
naire that has been found to be sensitive and specific for signed specifically for use with adolescents. Most re-
predicting current hazardous use of alcohol and, to a cently, the Problem-Oriented Screening Instrument for
slightly lesser extent, lifetime diagnosis of alcohol de- Teenagers (POSIT) has received considerable atten-
pendence.13 Among adolescents, however, AUDIT lacks tion.17 It is a 139-item self-administered yes/no question-
sufficient sensitivity to make its use practical.14 naire that was developed by the National Institute on Drug
The CAGE questions have also achieved wide- Abuse as part of the Adolescent Assessment/Referral Sys-
spread use.15 This instrument’s name is a mnemonic of tem, a comprehensive battery that is designed to screen,
the following 4 yes/no questions: “Have you ever felt that assess, and guide treatment decisions. The POSIT ques-
you should cut down on your drinking?” “Have people tionnaire comes in both English and Spanish versions,
annoyed you by criticizing your drinking?” “Have you ever and a computer-based CD-ROM version is presently un-