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 TRAUMA

Revisiting the ‘bag of bones’


FUNCTIONAL OUTCOME AFTER THE CONSERVATIVE
MANAGEMENT OF A FRACTURE OF THE DISTAL HUMERUS

S. A. Aitken, The best method of managing a fracture of the distal humerus in a frail low-demand patient
P. J. Jenkins, with osteoporotic bone remains controversial. Total elbow arthroplasty (TEA) has been
L. Rymaszewski recommended for patients in whom open reduction and internal fixation (ORIF) is not
possible. Conservative methods of treatment, including the ‘bag of bones’ technique
From Glasgow Royal (acceptance of displacement of the bony fragments and early mobilisation), are now rarely
Infirmary, Glasgow, considered as they are believed to give a poor functional result.
United Kingdom We reviewed 40 elderly and low-demand patients (aged 50 to 93 years, 72% women) with
a fracture of the distal humerus who had been treated conservatively at our hospital
between March 2008 and December 2013, and assessed their short- and medium-term
functional outcome.
In the short-term, the mean Broberg and Morrey score improved from 42 points (poor; 23 to
80) at six weeks after injury to 67 points (fair; 40 to 88) by three months.
In the medium-term, surviving patients (n = 20) had a mean Oxford elbow score of 30
points (7 to 48) at four years and a mean Disabilities of the Arm, Shoulder and Hand score of
38 points (0 to 75): 95% reported a functional range of elbow flexion. The cumulative rate of
fracture union at one year was 53%. The mortality at five years approached 40%.
Conservative management of a fracture of the distal humerus in a low-demand patient
only gives a modest functional result, but avoids the substantial surgical risks associated
with primary ORIF or TEA.
Cite this article: Bone Joint J 2015;97-B:1132–8.

Fractures of the distal humerus account for 1% surgery were substantial. Our reasoning was
 S. A. Aitken, MD, FRCS (Tr &
of fractures sustained by adults: two-thirds of that conservative treatment might give an
Orth), Orthopaedic Registrar, those affected are aged 50 years or older.1 Most acceptable result, thereby avoiding unneces-
Department of Trauma and
Orthopaedics
distal humeral fractures are routinely treated by sary surgery. Furthermore, we took the view
Royal Infirmary of Edinburgh, open reduction and internal fixation (ORIF), that patients who had a poor result from con-
51 Little France Crescent,
Edinburgh, EH16 4SA, UK.
but this is controversial in the frail, elderly and servative treatment could undergo TEA at a
low-demand patient with osteoporotic bone. later date in a virgin joint.
 P. J. Jenkins, MD, FRCSEd
(Tr & Orth), Consultant Total elbow arthroplasty (TEA) has been rec- We are aware of only two reports in the
Orthopaedic Surgeon, ommended in cases in which the fracture is literature which document the functional out-
Department of Trauma and
Orthopaedics often very distal, displaced and comminuted.2 come of conservative management using a
 L. Rymaszewski, MBChB, Conservative methods of treating a fracture of modern validated scoring system.7,8
FRCS, Consultant Orthopaedic
Surgeon, Department of the distal humerus, including the ‘bag of bones’ The aim of this study was to present the
Trauma and Orthopaedics technique in which the position of the displaced short- and medium-term functional outcomes
Glasgow Royal Infirmary, 84
Castle Street, Glasgow, G4 0SF, fragments is accepted and early movement of primary conservative treatment of a fracture
UK. encouraged, are now rarely considered as they of the distal humerus in elderly and low-
Correspondence should be sent are thought to give poor functional results.3 This demand patients.
to Mr S. A. Aitken; e-mail:
stuart.aitken@nhs.net
is, in part, because of selected results, historical
reports and small case series.4,5 There has, how- Patients and Methods
©2015 The British Editorial
Society of Bone & Joint
ever, been little written on the subject since the This study describes the clinical outcomes of a
Surgery early report of 12 conservatively managed cases retrospectively compiled case series of patients
doi:10.1302/0301-620X.97B8.
35410 $2.00
by Eastwood in 1937.6 managed using a standard method of treat-
We present our experience of the conservative ment. Consequently, formal ethics committee
Bone Joint J
2015;97-B:1132–8. management of fractures of the distal humerus approval was not required from the Regional
Received 4 November 2014; in selected elderly and low-demand patients for Ethics Committee. There was no external
Accepted after revision 2 April
2015 whom the inherent risks of anaesthesia and funding for this study.

1132 THE BONE & JOINT JOURNAL


REVISITING THE ‘BAG OF BONES’ 1133

We reviewed the case notes and radiographs of all ion, pronation and supination (40 points), strength
patients aged 50 years or more with a fracture of the distal (20 points), stability (5 points) and pain (35 points). A total
humerus which had been treated conservatively between of 95 to 100 points is rated excellent; 80 to 94 points, good;
March 2008 and December 2013 at our hospital. Our hos- 60 to 79 points, fair; and less than 60 points, poor. The
pital serves a predominantly urban population, 50% of number and timing of review appointments varied between
whom reside in the most deprived socioeconomic national patients and were pragmatically determined by the clinical
quintile, as measured by the Scottish Index of Multiple and social demands of this vulnerable group. For the pur-
Deprivation.9 The detrimental effect of deprivation on gen- pose of analysis, available data from various time points
eral health is well recognised.10 Many of our patients have were pooled and evaluated at approximately six weeks and
multiple medical co-morbidities and are deemed to be at a three months post injury. Patients with missing data were
higher risk for anaesthesia and surgery. Patients were iden- excluded from the short-term analysis.
tified through the hospital picture archiving and communi- Medium-term functional data. Surviving patients were con-
cation system by performing a search of all radiographs tacted by telephone and invited to participate in the study
taken in our elbow clinic. All patients were managed under by providing medium-term functional data. Patients were
the care of the senior author (LAR). The electronic patient excluded at this point if they were unable or did not wish to
record (EPR) and patient case files were used to obtain respond for any reason. Data were obtained for 20 patients
demographic data (age, gender, Charlson co-morbidity (50%). Of the remainder, 12 (30%) had died, five (12.5%)
index)11 and information about complications and subse- had developed cognitive impairment, one patient could not
quent surgical procedures. talk because of laryngeal cancer and one patient preferred
Fracture classification and radiographic measurements. All not to be interviewed. Contact details were unobtainable
anteroposterior (AP) and lateral radiographs of the for the one remaining patient (Fig. 1).
elbow joint were reviewed and classified by one author Patients were asked to complete the Oxford elbow score
(SAA) according to the Arbeitsgemeinshaft für (OES)14 and Disabilities of the Arm, Shoulder and Hand
Osteosynthesfragen (AO) system.12 Patients were (QuickDASH)15 questionnaires. The OES is a validated,
included if they had a 13-A (extra-articular), 13-B (partial elbow-specific, 12-question outcome measure providing a
articular) or 13-C (complete articular) type of fracture. The score from 0 (poor) to 48 (excellent). It served as our pri-
presence of comminution was noted, as was fracture dis- mary outcome measure for the medium-term time-point.
placement. Any intra-articular step in type B and C frac- The QuickDASH is a validated measure of upper limb dis-
tures was measured on the AP radiograph. Union was ability, but is not specific to the elbow joint. It provides a
defined radiologically by the presence of new bone forma- score from 0 (no disability) to 100 (severe disability).
tion across the fracture site on two views, supplemented by Patients were also asked about their current elbow pain
supporting information provided in the EPR by the exam- from 0 (none) to 10 (worst) while at rest, at night, during
ining clinician. heavy lifting, and during repetitive activities. They were
Treatment protocol. Conservative management of a frac- asked if they could get hand to mouth on the injured side, as
ture of the distal humerus was defined as non-operative a marker of elbow flexion. Finally, patients were asked to
treatment or surgical intervention limited to the early exci- rate their overall satisfaction with their course of treatment
sion of potentially impinging bony fragments. Conservative from 0 (totally unsatisfied) to 10 (entirely satisfied).
management was offered to selected patients after careful Baseline characteristics. A total of 40 patients aged 50
consideration of the injury pattern and the patients’ general years or more with distal humeral fractures were treated
health, medical comorbidities and level of function. The conservatively, of whom 29 (72.5%) were women. The
management options were discussed with the patient and a mean age of the cohort was 73.5 years (50 to 93).
shared decision made. Patients were initially treated in an Statistical analyses. The chi-squared test was used to com-
above-elbow plaster splint, but had this changed to a simple pare differences between proportions. Normally distrib-
sling at the first outpatient elbow clinic appointment uted continuous data were presented as the mean, standard
(within 14 days of injury). Patients were not referred for deviation (SD) and range. Medians with interquartile ranges
physiotherapy, but were encouraged to use and move the (IQR) were used when data were skewed. The Mann–
elbow as discomfort allowed. Notably, there was no pre- Whitney U or t-tests were used to compare continuous data
determined out-patient review protocol: patients were between two groups. Where more than two groups existed
reviewed in the clinic at various time-points until comfort- (e.g. AO fracture types), the Kruskal–Wallis test was used.
able and satisfied, or until surgical intervention was deemed As this was a retrospective observational study, each
necessary (delayed ORIF, TEA, ulnar nerve release). patient had a different period of follow-up and some had
Short-term functional data. The EPR was examined to died. The Kaplan–Meier method was used to estimate the
determine the clinical examination findings at out-patient cumulative proportion of patients achieving union without
review within one year of injury. Patients were evaluated intervention, and the proportion of patients requiring inter-
retrospectively according to the 100-point rating system of vention.16 The cut-off points studied were one and five years
Broberg and Morrey,13 which is based on the arcs of flex- post-injury. The log-rank test was used to compare cumula-

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1134 S. A. AITKEN, P. J. JENKINS, L. RYMASZEWSKI

Baseline
X-rays and EPR reviewed

n = 40 (100%)

Short-term review Lost to follow-up


Adequate clinic data n = 8 (20%)
< 40 days

n = 32 (80%)

Exclusions from final follow-up:


Lost to follow-up Died n = 12
Short-term review
n = 8 (20%) Cognitive impairment n = 5
Adequate clinic data
Communication difficulty n = 1
40 to 115 days
Declined to participate n = 1
Unable to contact n = 1
n = 24 (60%)

Final Lost to follow-up


medium-term review n = 4 (10%)
Telephone response

n = 20 (50%)

Fig. 1

Participant flow diagram. The reasons for exclusion at final follow-up are also shown. EPR, electronic patient record.

tive proportions between groups. Bivariate correlation was extension improved from 60° (20° to 85°; SD 18.8) to 49°
performed with age and articular displacement and the (30° to 80°; SD 18.6), (p < 0.001, paired t-test), mean flex-
functional outcomes of OES, QuickDASH and satisfaction. ion from 107° (90° to 140°; SD 8.3) to 120° (95° to 140°; SD
The level of significance was set at p < 0.05. 14.6), (p = 0.075, paired t-test), and mean forearm rotation
from 112° (45° to 170°; SD 28.0) to 141° (90° to 175°; SD
Results 18.0), (p = 0.01, paired t-test). The mean Broberg and Mor-
A Charlson comorbidity index of 2 or more was found in rey score improved by 25 points during short-term out-
22 (55.0%) patients and a history of alcohol abuse noted in patient review: from a “poor” 42.5 points (23 to 80;
16 (40%). A fall from a standing height accounted for 37 SD 12.2) to a “fair” 67.1 points (40 to 88; SD 13.5),
(92.5%) fractures: the remainder were the result of a fall (p < 0.001, paired t-test).
down multiple stairs. One patient sustained an associated Union and surgical intervention. The early excision of
fracture of the ipsilateral olecranon and seven (17.5%) an potentially impinging bony fragments was undertaken as a
injury elsewhere in the same limb. One fracture was open. planned procedure in five patients at a mean of 20 days (5 to
In total 28 fractures (70.0%) were displaced, 15 (37.5%) 49; SD 19.8) from injury. One patient died 20 days after
comminuted and 17 (42.5%) had articular incongruity, fracturing. Of the remaining 34 patients in whom bony
with a mean articular step of 5.2 mm (0 to 17, SD 3.8). As union could be assessed, 19 (55.9%) progressed to union
shown in Table I, 19 (47.5%) fractures were AO type A, and 15 developed nonunion (44.1%). Of those with united
seven (17.5%) type B and 14 (35.0%) type C. fractures, one patient (5.3%) underwent TEA after three
Short-term functional outcome. The first pooled out-patient months for stiffness and poor function in an already
dataset was recorded at a mean of 40 days (5 to 78; SD 31.7) severely eroded rheumatoid elbow. Of the 15 patients with
post-injury and the second at 115 days (23 to 209; SD 88). nonunion, surgery was carried out in five (33.3%): one
After excluding missing information, adequate data were ulnar nerve release at 18 months; two delayed ORIF for
available for 32 (80%) patients at the first review and 24 pain at three and 13 months and two TEA for pain at nine
(60%) at subsequent review. There were 21 (53%) patients and 17 months. There was no statistically significant differ-
with flexion-extension data for both the first and second ence in the incidence of surgical intervention between union
visit, and 13 (33%) with forearm rotation data. Mean and nonunion groups (p = 0.066, Fisher’s exact test). The

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REVISITING THE ‘BAG OF BONES’ 1135

Table I. Demographic data, functional outcomes and the incidence of surgical intervention, arranged by Arbeitsgemeinshaft für
Osteosynthesfragen (AO) fracture type

AO fracture type
A B C p-value
Total number (n, %) 19 (47.5) 7 (17.5) 14 (35.0) -

Age (yrs) (SD, range) 78.9 (9.1, 62 to 93) 62.9 (11.7, 50 to 87) 71.6 (7.6, 52 to 81) 0.001 KW

Gender ratio (male:female) 6:13 2:5 3:11 0.810 CHI

Union without intervention (n, %) 8 of 18 (44.4) 2 of 4 (50.0) 9 of 12 (75.0)

Surgical intervention (n, %)


None 17 (89.4) 2 (28.6) 10 (71.4)
Excision of fragments 0 3 (42.8) 2 (14.3)
Ulnar nerve release 0 1 (14.3) 0
Late ORIF 1 (5.3) 1 (14.3) 0
TEA 1 (5.3) 0 2 (14.3)

Medium-term outcome (n = 20) (IQR) All MWU


OES 19 (14.5 to 34.5) 45 (10.5 to 46.0) 33 (20.3 to 44.3) 0.706
QuickDASH score 61.4 (31.8 to 70.5) 2.3 (2.3 to 70.5) 30.6 (16.0 to 59.7) 0.388
Pain rating
At rest 6 (2 to 7) 0 (0 to 5) 2.5 (0 to 5) 0.250
At night 6 (2.5 to 8) 0 (0 to 5.5) 3 (0.75 to 6.25) 0.217
On heavy lifting 9 (4.5 to 9.5) 2 (1 to 9.5) 5.5 (2.25 to 9) 0.560
On repetitive movement 8 (4.5 to 9) 2 (1 to 8.5) 5 (1.5 to 6.25) 0.283
Satisfaction rating 7 (3.5 to 9.0) 9 (3.5 to 9.5) 7 (5.0 to 9.0) 0.940
SD, standard deviation; KW, Kruskal–Wallis test; CHI, chi-squared test; ORIF, open reduction and internal fixation; TEA, total elbow
arthroplasty; IQR, interquartile range; MWU, Mann–Whitney U test; QuickDASH, Disabilities of the Arm, Shoulder and Hand;
OES, Oxford elbow score

Table II. Fracture union at one and five years post-injury, patient mortality and surgical inter-
vention, constructed according to the Kaplan–Meier method. For union or intervention,
patients were censored from follow-up at death or the end of the study period

One year (%) (95% CI) Five years (%) (95% CI)
Cumulative union 52.6 (34.7 to 67.8) 73.3 (57.7 to 83.9)

Cumulative mortality 10.5 (0.2 to 43.0) 38.8 (16.3 to 61.1)

Cumulative intervention (all)


All 18.9 (2.9 to 45.4) 28.9 (9.6 to 51.8)
Type A 11.5 (3 to 38.7) 11.5 (3 to 38.7)
Type B 42.9 (16.3 to 82.8) 71.4 (38.8 to 95.9)
Type C 22.1 (7.7 to 54.1) 29.9 (12.4 to 61.5)
Log-rank test p = 0.309

Cumulative intervention (excluding fragment excision)


Type A 11.5 (0 to 46.8) 11.5 (0 to 46.8)
Type B 0 33.3 (1.2 to 76.2)
Type C 7.7 (0 to 69.7) 15.4 (0 to 62.7)
Log-rank test p = 0.966
CI, confidence interval

greatest overall incidence of surgical intervention occurred injury. Of these, eight had fractures which had united, eight
in the AO type B group: three out of five of these proce- had a nonunion and four had an early planned excision of
dures, however, involved the planned removal of fragments fragments. Overall, 19 (95%) patients were able to reach
(Table I). Table II shows the cumulative rates of fracture their mouth with their hand, suggesting a functional range
union, patient mortality, and surgical intervention for the of elbow flexion. The mean satisfaction score was 7.1 (0 to
study cohort. 10; SD 2.7) and 15 (75%) patients provided a score of 7 or
Medium-term functional outcome. A total of 20 patients greater. The mean overall OES was 30.0 points (7 to 48;
provided data at a mean of 46 months (5 to 73; SD 20) from SD 14.3), with a mean QuickDASH of 38.5 (0 to 75;

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1136 S. A. AITKEN, P. J. JENKINS, L. RYMASZEWSKI

Table III. Medium-term function and satisfaction arranged by union status. Data are presented as medians with interquartile ranges
(IQR) unless otherwise stated

Function and satisfaction


Final result OES QuickDASH Satisfaction
Union (n = 12) 39.5 (IQR 20.5 to 45) 28.7 (IQR 2.3 to 58.0) 8 (IQR 4.5 to 9.5)
Nonunion (n = 8) 20.0 (IQR 12.3 to 39) 59.1 (IQR 29.6 to 72.7) 7 (IQR 4.8 to 8.8)
p-value* 0.231 0.069 0.557
* Mann–Whitney U test
OES, Oxford elbow score; QuickDASH, Disabilities of the Arm, Shoulder and Hand

10 in those whose fracture had united (median 3, IQR 0.5


to 6), (p = 0.032, Mann–Whitney U test).
Visual analogue scale (median, IQR)

Discussion
We have described the patient-reported functional out-
comes in a series of low-demand patients with a conserva-
tively managed fracture of the distal humerus. We believe
5 our results support this approach in selected ‘high-risk’
cases if doubt exists as to whether stable fixation can be
achieved. Elbow movement and pain can be expected to
improve in the short-term. At around four years most of
our patients reported a functional range of elbow flexion
and satisfaction with their treatment. We found our cumu-
lative surgical intervention rate to be less than 30% in the
0
Rest pain Night pain Heavy Repetitive five years after injury.
lifting activity The increased risk of ORIF in patients with a commi-
Fig. 2
nuted fracture and osteoporotic bone is well recognised. In
2005, Korner et al reported the results of ORIF in 45
Graph showing the results of the medium-term pain assessment
(n = 20), from 0 = no pain to 10 = worst pain, presented according
patients with a median age of 73 years (IQR 61 to 92).17
to patient activity. The median scores and interquartile ranges Implant failure and/or loosening of the distal screws
(IQR) are shown.
occurred in 12 patients, necessitating revision surgery in
seven. Similarly, TEA for elbow trauma and its sequelae is
not without risk; high re-operation rates have been
reported, even from the most experienced centres.2,3 As the
SD 28.2). There was no difference seen in the distribution of incidence of elective TEA for arthritis has been steadily fall-
functional outcome scores (OES, QuickDASH) between ing over the last 20 years, and implant survivorship is
AO fracture types (Table I) or between those patients with related to surgeon volume,18 it seems appropriate that com-
fractures which united and those which did not (Table III). plex trauma cases requiring TEA should be managed elec-
No difference in outcome between men and women tively by the most appropriate surgeon rather than as a
was noted (OES p = 0.314; QuickDASH p = 0.826; satis- ‘trauma’ procedure.
faction p = 0.586). There was no correlation (Spearman’s The available literature on the outcomes of conserva-
rho) between patient age and OES (p = 0.087, p = 0.715), tively treated fractures of the distal humerus contains a
QuickDASH (p = 0.016, p = 0.945) or satisfaction small number of conflicting reports, published over many
(p = 0.134, p = 0.562). Similarly, fracture displacement decades. During this time, there has been a shift from the
had no association with OES (p = 0.012, p = 0.959), use of surgeon-reported measures to patient-reported out-
QuickDASH (p = -0.183, p = 0.440), or satisfaction come measures and a change in the expectations of patients
(p = -0.034, p = 0.883). as to what constitutes an acceptable outcome following
The medium-term distribution of pain scores provided is injury. In 1937, Eastwood reported a “most satisfactory”
shown in Figure 2. There was no difference in the distribu- result in 14 cases treated by manipulation and temporary
tion of pain scores between patients with united and unu- immobilisation, with 12 of 14 patients able to return to
nited fractures in terms of rest pain (p = 0.080, Mann– their previous employment.6 In 1969, Riseborough and
Whitney U test), night pain (p = 0.182, Mann–Whitney Radin identified 13 good, five fair and four poor results,
U test) or pain on heavy lifting (p = 0.133, Mann–Whitney using a measure primarily based on the range of movement
U test). The pain was greater on repetitive activity in achieved after either manipulation or skeletal traction.19 By
patients with a nonunion (median 8, IQR 5.5 to 8.75) than the 1970s, Brown and Morgan noted five good, four fair

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REVISITING THE ‘BAG OF BONES’ 1137

and one poor result after a regimen of early active elbow to identify predictors of a poor functional result, but was
movement.4 perhaps to be expected given that we were examining an
In 1983, Zagorski et al5 reported mostly unsatisfactory elderly and high-risk cohort whose cumulative five-year
results (one good, three fair and seven poor) after non- mortality approached 40%.
operative treatment using a number of different methods. In conclusion, the conservative management of a fracture
Similarly, Srinivasan et al,8 reporting on a small series of of the distal humerus in a low demand patient gives only a
eight patients in 2005, found 75% unsatisfactory results modest functional result but avoids the potential surgical
(fair or poor) according to the Orthopaedic Trauma Associ- risks associated with ORIF or TEA. The relevant advan-
ation grading system, despite no cases of fracture nonunion. tages and disadvantages of both surgical and non-surgical
In contrast, Pidhorz et al7 have recently (2013) published options should be discussed, before any informed decision
largely successful results from a combined retrospective is made. If there is failure to improve, delayed TEA can still
and prospective series of 56 patients aged 65 years or more be offered at a later date as an elective procedure. While
with a fracture of the distal humerus treated by temporary potentially technically more demanding than acute arthro-
splintage then mobilisation. Remarkably, 75% were pain plasty, a delayed TEA procedure does not necessarily com-
free by 20 months with a mean QuickDASH of 31 and promise functional outcome or confer a greater risk of
75% good or excellent results as measured by the Mayo complications to the patient.25
Elbow Performance Score. Author contributions:
We chose the OES as our primary measure of functional S. A. Aitken: Concept, Data collection, Analysis, Paper writing, Revisions.
P. J. Jenkins: Concept, Analysis, Paper writing.
outcome in the medium-term, as it was not logistically fea- L. Rymaszewski: Concept, Performed operations, Paper writing, Revisions.
sible to recall each patient for a more thorough clinical
No benefits in any form have been received or will be received from a commer-
examination. When measured against a ‘normative’ or cial party related directly or indirectly to the subject of this article.
‘excellent’ score of 47 or 48 in age-matched and uninjured This article was primary edited by P. Page and first proof edited by A. C. Ross.
individuals,20 the median score of 30 identified in our
cohort reflects a ‘fair’ outcome. However, as depicted in References
Tables I and III, the IQRs around the median score values 1. Aitken SA. The epidemiology of upper limb, lower limb and pelvic fractures in adults.
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